Clinical trials: Food Sensitivity
Digestive Health, Gastrointestinal Health
The Effects of Oral Fructanase Administration on Gastrointestinal Symptoms After Inulin Challenge in Healthy Adults
The carbohydrate inulin (from chicory root) is a healthy prebiotic ingredient found in dietary supplements and fortified foods (Nagy et al).
- Conditions
- Digestive Health, Gastrointestinal Health, FODMAP Intolerance, Food Sensitivity
- Trial name
- NCT06628869
- Testing
- Fructanase
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BIO-CAT, Inc.
Prediabetes, Brain Insulin Sensitivity
Long-term Effects of Avocado Consumption on Health in Pre-diabetic Individuals
Primary aim of the study is to assess the effect of 12-week daily avocado consumption on cerebral blood flow and markers of cardio- and vascular health in both, the periphery and the brain, in pre-diabetic individuals with…
- Conditions
- Prediabetes, Brain Insulin Sensitivity, Cerebral Blood Flow, Satiety and Food Intake
- Trial name
- NCT07752225
- Testing
- Avocados
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Maastricht University Medical Center
Healthy, Brain Insulin Sensitivity
Long-Term Effects of Walnut Consumption on Brain Function
Rationale: Healthy foods, including mixed nuts, may improve brain function, which is essential for cognitive and metabolic health, and may contribute to improved food intake regulation.
- Conditions
- Healthy, Brain Insulin Sensitivity, Cerebral Blood Flow, Brain Vascular Function
- Trial name
- WalBrain (NCT07422220)
- Testing
- Walnuts
- Where
- Netherlands
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Irritable Bowel Syndrome, Food Sensitivity
Brachyspira and Intestinal Allergy-like Immune Reactions in Patients With Irritable Bowel Syndrome (IBS)
The aim of this study is to define local immune responses in the GI tract to food antigens in IBS patients, with and without Brachyspira infection, using advanced imaging.
- Trial name
- NCT06413004
- Testing
- Elimination and re-introduction of CLE or COLAP positive food item(s)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Magnus Simrén
Allergic Contact Dermatitis, Metal Allergy
Environmental Exposure to Heavy Metals, Nanoparticles, and Emergent Contaminants and Risk of Allergic Diseases
The goal of this clinical trial is to collect environmental, bio-humoral, and clinical data derived from patients with allergic contact dermatitis (ACD) and systemic metal allergic syndromes related to the exposure to heavy…
- Conditions
- Allergic Contact Dermatitis, Metal Allergy, Food Allergy, Nickel Sensitivity
- Trial name
- MATRIOSKA (NCT06529913)
- Testing
- Collection of environmental, biological, and clinical data
- Where
- 2 sites in Italy
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Taste Sensitivity, Umami Taste Perception
Umami Taste Intensity and Meal Intake
Sweet and salty tastes can influence food intake. Increased intensity of these tastes has been shown to decrease food intake and increase satiation compared to the less intense taste, independent of palatability.
- Conditions
- Taste Sensitivity, Umami Taste Perception, Food Intake Regulation, Hedonic Function
- Trial name
- OptUmami (NCT07421466)
- Testing
- Hedonic mapping, Ad libitum risotto test meal
- Where
- Netherlands
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Taste Sensitivity, Umami Taste Perception
Umami Taste Intensity and ad Libitum Meal Intake
Background Sweet and salty tastes can influence food intake {Sørensen, 2003 #40}. Increased intensity of these tastes has been shown to decrease food intake and increase satiation compared to the less intense taste, independent…
- Conditions
- Taste Sensitivity, Umami Taste Perception, Food Intake Regulation, Hedonic Function
- Trial name
- RiceSort (NCT07059117)
- Testing
- Hedonic mapping, Ad libitum risotto test meal
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Food Hypersensitivity, Anaphylaxis
A Registry for the Food Allergy Community
The FARE Patient Registry will serve as a prospective, observational food allergy reporting system that stores detailed health and other basic information about patients' real-world experiences with food allergies, to encourage…
- Conditions
- Food Hypersensitivity, Anaphylaxis, Eosinophilic Esophagitis, Food Sensitivity
- Trial name
- FPR (NCT04653324)
- Where
- United States
- Volunteers
- 23,000 people
- Sponsor
- Food Allergy Research & Education
Irritable Bowel Syndrome, Food Sensitivity
Confocal Laser Endomicroscopy to Determine Influence of Food Antigens on Mucosal Integrity
Irritable bowel syndrome (IBS) is mainly associated with food intolerance and presents a particular challenge in gastrointestinal practice.
- Conditions
- Irritable Bowel Syndrome, Food Sensitivity, Healthy Controls
- Trial name
- RDS_CLE (NCT05056610)
- Testing
- food antigens on duodenal mucosa
- Where
- Germany
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Food Sensitivity
Effect of Personalized Elimination Diet on Food Sensitivity Related Symptoms
The goal is to identify food sensitivity in patients and assess whether the avoidance of the reaction-inducing foods via an 'elimination diet' leads to improvement in patient symptoms and overall well-being.
- Trial name
- NCT05389683
- Testing
- Elimination Diet
- Where
- 9 sites in United States
- Volunteers
- 80 people
- Sponsor
- Vibrant America Clinical Lab
Food Sensitivity
Effects of Different Polyphenol-containing Beverages on the Immune System and on Muscular Growth Factors
In this research project, the effect of different polyphenol-containing beverages with varying alcohol content of < 0.4 vol% on immune function as well as muscular growth factors will be investigated
- Trial name
- NCT04983420
- Testing
- non-alcoholic Pilsner, non-alcoholic wheat beer, apple spritzer
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Food Allergy, Food Hypersensitivity
Hydroponic Cultivation in Systemic Nickel Allergy Syndrome
Oral intake of nickel (Ni) is capable of causing the onset of systemic disorders in patients with Systemic Allergy to Nickel Syndrome (SNAS), an emerging allergic condition.
- Conditions
- Food Allergy, Food Hypersensitivity, Nickel Sensitivity
- Trial name
- DATTERINO (NCT05232890)
- Testing
- Datterino tomato purée from hydroponic technology, Datterino tomato puree from conventional cultivation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Catholic University of the Sacred Heart
Individual Difference, Food Sensitivity
Modifying Whey Protein Fortified Drinks and Foods
This study aims to investigate whether consumers differ in mouthdrying sensitivity and if mouthdrying can be modulated.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT04869722
- Testing
- Liquid Model, Solid Model
- Where
- United Kingdom
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Reading
Individual Difference, Food Sensitivity
Investigating the Influence of Age and Saliva Flow on the Perception of Protein Fortified Foods and Beverages
Brief Summary: This study aims to investigate whether protein fortification of foods and beverages causes mouthdrying and mucoadhesion and whether this is influenced by age and saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT04302779
- Testing
- Solid Model, Liquid Model
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Reading
Individual Difference, Food Sensitivity
Investigating Consumers Perception and Acceptance of Whey Beverages
Brief Summary: This study aims to investigate whether protein fortification of beverages causes mouthdrying and mucoadhesion and whether this is influenced by saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT04507399
- Testing
- Liquid Model
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Appetitive Behavior, Individual Difference
The Influence of Fat Perception on Satiety From Consumption of Reduced Fat Snacks
The present study aims to investigate the effect of fat level and fat type of a snack on self-reported satiety and associated biomarkers. The relevant individual differences will also be investigated.
- Conditions
- Appetitive Behavior, Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT03585920
- Testing
- Expanded Corn Snack
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Individual Difference, Food Sensitivity
Investigation of the Perception of Protein Fortified Foods and Beverages
This study aims to investigate whether protein fortification of foods and beverages causes mouthdrying and mucoadhesion and whether this is influenced by age and saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT03798730
- Testing
- Solid Model, Liquid Model
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Reading
Non-coeliac Gluten Sensitivity
Effect of AN-PEP Enzyme on Gluten Digestion in Gluten Sensitive Individuals
In this trial, the effect of a low and a high dose AN-PEP will be investigated in gluten sensitive individuals. Volunteers receive a breakfast with background (0.5 g) gluten.
- Trial name
- AN-PEP-03 (NCT02060864)
- Testing
- AN-PEP
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- DSM Food Specialties
Milk Hypersensitivity, Food Sensitivity
Evaluation of the Efficacy of a New Formula in Infants With Cow's Milk Protein Allergy
The aim of the study is to show the efficacy, tolerance and nutritional adequacy of a newly developed hydrolyzed rice formula in infants with a proven cow's milk protein allergy.
- Conditions
- Milk Hypersensitivity, Food Sensitivity, Protein Allergy
- Trial name
- Paradice (NCT01998074)
- Testing
- extensively hydrolyzed rice protein formula
- Where
- Belgium
- Sponsor
- United Pharmaceuticals
Food Sensitivities, Headache
NAET Screening for Food Allergy, Sensitivity and Intolerances Using IgE-Specific Antigen Test and NST- NAET®
Food allergy reactions cause various health disorders in sensitive people. These reactions may be IgE-mediated,cell-mediated, energy disturbance-mediated, or a combination of the three.
- Conditions
- Food Sensitivities, Headache, Backache, Indigestion
- Trial name
- NCT00275795
- Testing
- NAET Procedures
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nambudripad's Allergy Research Foundation