Clinical trials: Food Sensitivity
Food Hypersensitivity
Epidemiological Investigation and Cohort Study on Food Allergy in Children Aged 3 to 6 Years in Wenzhou and Taizhou Urban Areas
Objective 1. To investigate the status of food allergy among children aged 3 to 6 in Wenzhou and Taizhou urban areas. 2. To obtain the self-reported rate of parents or guardians of food allergy among children aged 3 to 6 in…
- Trial name
- NCT03974555
- Where
- China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Allergy;Food, Food Allergy Peanut
TRANS-FOODS: Preventing Peanut Allergy Through Improved Understanding of the Transcutaneous Sensitisation Route, Novel Food Processing and Skin Care Adaptations
This project aims to study the immune responses to peanut allergen in those with a skin barrier defect with and without skin massage, specifically it aims to: 1.
- Conditions
- Allergy;Food, Food Allergy Peanut, Pathways and Sources of Exposure
- Trial name
- TRANS-FOODS (NCT05407012)
- Testing
- Application of the barrier enhancing preparation.
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King's College London
Chronic Spontaneous Urticaria (CSU), Healthy Volunteers
Phase Ib, Randomized, Double-blind, Placebo-Controlled, Dose-Escalation Study of Alpha-0261 Tablets to Assess Safety and Tolerability in Patients With Chronic Spontaneous Urcaria (Part 1) and Food Effect in Healthy Adults (Part 2).
This is a randomized, double-blind, placebo-controlled phase 1b clinical study to evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of Alpha-0261 Tablets in healthy Chinese adults and in patients with…
- Trial name
- NCT07684560
- Testing
- Alpha-0261
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AlphaMol Science Ltd. (Shanghai)
Eosinophilic Esophagitis, Gastroesophageal Reflux Disease
Morphological Markers of Gastroesophageal Reflux Disease (GERD)
The purpose of this project is to learn more about a new and promising way to diagnose acid reflux disease using a very high-powered microscope.
- Trial name
- NCT01921686
- Testing
- Sample collection and Questionnaire
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Functional Bowel Disorder, Irritable Bowel Syndrome
The 5Ad Diet for Functional Bowel Disorders
The goal of this randomised controlled trial (RCT) is to compare the efficacy of the newly developed 5Ad diet against the widely researched low fermentable oligo-, di-, monosaccharide and polyols (FODMAP) diet in reducing…
- Conditions
- Functional Bowel Disorder, Irritable Bowel Syndrome, Food Intolerance, Food Intolerance Syndromes
- Trial name
- NCT06338189
- Testing
- The 5Ad Diet, The Low FODMAP Diet
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Suffolk
The Quality of Life of Parents of Children With Food Allergy
Online Mindfulness-based Cognitive Therapy for Parents of Children With Food Allergies
This study aims to conduct an initial evaluation of adapted, live online, mindfulness-based cognitive therapy for parents and carers of children with food allergies (MBCT-PCCFA).
- Trial name
- NCT04738890
- Testing
- Mindfulness-based cognitive therapy, Treatment as usual
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Sucrase Isomaltase Deficiency
Genetic Carbohydrate Maldigestion As Model to Study Food Hypersensitivity Mechanism (WORK PACKAGE 2)
Irritable bowel syndrome (IBS) affects one in seven people with gastrointestinal (GI) symptoms that are detected without an established underlying organic cause.
- Trial name
- GenMalCarb2 (NCT06770907)
- Testing
- Blood, stool and saliva collection, Questionnaire completion, Magnetic Resonance Imaging (MRI) and Breath test
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Food Allergy, Quality of Life
The Feasibility of Systemic Reaction After Contact Exposure to the Allergenic Food in Children With Known Food Allergy
The prevalence of food allergy in the western world is a growing health problem. The majority of reactions are caused due to oral exposure to the known food allergen.
- Trial name
- NCT05080127
- Testing
- application of the allergenic food
- Where
- 2 sites in Israel
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Seasonal Allergic Rhinitis
A Single and Multiple Dose Study to Explore the Safety of JNJ-38224342 in Healthy Patients and Patients With Seasonal Allergies
A single and multiple dose study to assess the safety of JNJ 38224342 compared to placebo in healthy volunteers and in volunteers with seasonal allergies.
- Trial name
- NCT01054352
- Testing
- JNJ38224342
- Where
- Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Food Allergy
Endomicroscopy in Patients With Food Allergy: a New Diagnostic Option
The purpose of this study is to evaluate the endoscopic diagnostic options of the endomicroscopy in patients with food intolerance.
- Trial name
- NCT01072084
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Healthy
Drug-drug Interaction and Food-effect Study With GLPG4716 and Midazolam in Healthy Subjects
The purpose of this study is to determine the effect of the administration of multiple doses of GLPG4716 on the amount of midazolam (MDZ) that gets into the blood when the two drugs are administered together compared to when…
- Trial name
- NCT05030857
- Testing
- GLPG4716, Midazolam
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Lakefront Biotherapeutics NV
Immunoglobulin E-Mediated Food Allergy, Immunoglobulin G4-Related Disease
Immunoglobulin G4 and Immunoglobulin E Antibodies in a Population With Adverse Reactions to Foodstuffs-related Symptoms
The aim of this study is to analyze a population with symptoms associated with adverse reactions to foodstuffs (ARFS). To determine the levels of food-specific immunoglobulin G4 (IgG4) and immunoglobulin E (IgE) antibody…
- Conditions
- Immunoglobulin E-Mediated Food Allergy, Immunoglobulin G4-Related Disease, Symptoms and Signs, Adverse Reaction to Food
- Trial name
- NCT05681975
- Testing
- Food-specific Immunoglobulin G4 and/or Immunoglobulin E antibody reactions
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Inflammatory Bowel Diseases, Quality of Life
Effect of Probiotic Administration on Patients With Inflammatory Bowel Disease
The study is a single-center, randomized, single-blinded, controlled trial conducted at ZHUMC's endoscopy unit. It aims to assess the short-term effects of probiotic administration on disease course, quality of life, and…
- Conditions
- Inflammatory Bowel Diseases, Quality of Life, Food Intolerance, Flare Up
- Trial name
- NCT06392061
- Testing
- Trilac
- Where
- Lebanon
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lebanese University
Atopic Dermatitis
A Clinical Study of HRS-8797 in Healthy Participants
The purpose of this phase I study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of HRS-8797 in healthy participants.
- Trial name
- NCT07698756
- Testing
- HRS-8797
- Where
- China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Chengdu Suncadia Medicine Co., Ltd.
Food Allergy
Therapeutic Effect of Chinese Herbal Medicine on Food Allergy
The increasing prevalence of allergic diseases in westernized countries poses a significant health problem and a tremendous burden on quality of life and healthcare expenditure.
- Trial name
- FAHF-2 (NCT00602160)
- Testing
- FAHF-2 (TM)
- Where
- 2 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Li, Xiu-Min, M.D.
Perimenopause, Cognitive Function in Perimenopause
Cognitive Task Sensitivity in Perimenopause and Nutritional Status
Perimenopause is when you have symptoms of menopause but your periods have not stopped. Brain-related changes are just one of the many symptoms that occur, and changes to memory and concentration ("brain fog") are frequently…
- Trial name
- NCT07648667
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Cow Milk Allergy
Growth of Infants With Cow's Milk Allergy Fed an Amino Acid-based Formula Containing Two Human Milk Oligosaccharides
The main aim of this study is to provide longitudinal growth data in infants with moderate-to-severe cow's milk allergy fed an amino acid-based formula with two added human milk oligosaccharides.
- Trial name
- PLATYPUS (NCT03661736)
- Testing
- Food for Specific Medical Purpose
- Where
- Australia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Tree Nut Allergy, Food Allergy
Thresholds In Food Allergy evaluaTion And predictioN
Thresholds In food allergy evaluaTion And predictioN, a prospective, observational registry. The aim is to quantify food allergy thresholds in Canada and their clinical predictors.
- Trial name
- TITAN (NCT06038019)
- Testing
- Oral food challenge
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Healthy, Gastrointestinal Cancer
Dietary Nitrate and Nitrite Intake and Phosphate Biomarkers and Risk of Chronic Diseases
Nitrate, nitrite, and phosphate (NO3, NO2, P) are at all age stages ubiquitous in our everyday foods, including naturally occurring and as food additives, and in our drinking water.
- Conditions
- Healthy, Gastrointestinal Cancer, Cardiovascular Diseases, Chronic Obstructive Airway Disease
- Trial name
- NCT07746310
- Where
- Sweden
- Volunteers
- 86,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Cow's Milk Allergy
Oral Tolerance in Cow's Milk Allergy in the Infant
This study aims to determine if there is a link between cow's milk allergy in infants and regulatory T cells dysfunction that should be transient in infant acquiring oral tolerance after 12 month avoiding food and persistent in…
- Trial name
- NCT00298376
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon