Clinical trials: Food Systems
Multiple Sclerosis
Phase I Study Evaluating Safety and Tolerability of Escalating Single and Multiple Doses of of PIPE-307 and Food Effect in Healthy Volunteers
This is a randomized, double-blind study of PIPE-307 or placebo in normal healthy subjects. The study will be conducted in three parts: Part 1 will be a Single Ascending Dose (SAD) study enrolling approximately 48 subjects for a…
- Trial name
- NCT04725175
- Testing
- PIPE-307
- Where
- Australia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Contineum Therapeutics
Food Allergy
Can Vitamin D Supplementation in the First Year of Life Prevent Food Allergy in Infants? The VITALITY Trial: Parts 1&2
We report that Australia has the highest prevalence of Immunoglobulin(Ig)E-mediated food allergy in the world, with 10% of infants having challenge-proven food allergy in Melbourne.
- Trial name
- VITALITY (NCT02112734)
- Testing
- Vitamin D
- Where
- Australia
- Volunteers
- 2,739 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Obesity, Diabetes
The Effects of Carbohydrate Source on Food Intake, Blood Glucose and Gut Hormone Response in Healthy Children
This study will compare the effects of commonly consumed carbohydrate sources such as potatoes, pasta and rice along with a fixed portion of meat on blood glucose, satiety and insulin levels among healthy body weight children.
- Trial name
- NCT02499107
- Testing
- Rice treatment, Pasta treatment, Boiled and mashed potato treatment
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes (T2DM), Obesity & Overweight
Optimizing Lifestyles Through Increased Vegetable-rich Eating Pilot Study
The goal of this pilot clinical trial is to examine how receipt of ingredients for a Mediterranean diet (with or without nutrition classes) impacts Type 2 Diabetes Mellitus risk factors among adults in the US South.
- Trial name
- OLIVE Pilot (NCT07509502)
- Testing
- Dietary Intervention Teaching Kitchen (TK) Classes, Food is Medicine Grocery Provision (FiM)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Vitamin D Deficiency, Diabetes Mellitus
Vitamin D Supplementation on Metabolic Syndrome Indicators Among Older Adults, Alborz Province, Iran
General objective: To assess the effect of vitamin D supplementation on metabolic syndrome among food insecure and vitamin D deficient older adults in Karaj city, Alborz province in Iran.
- Conditions
- Vitamin D Deficiency, Diabetes Mellitus, Hypertension, Lipid Metabolism Disorders
- Trial name
- NCT03193944
- Testing
- D-vitin, soft gelatin capsule (vitamin D3,50000 IU)
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alborz Medical University
Food Allergy, Food Allergy in Children
Effect of Omalizumab in the Skin of Food Allergy Patients
The goal of this interventional study is to evaluate whether skin barrier abnormalities occur in subjects with a food allergy, as determined by positive oral food challenge (OFC).
- Trial name
- NCT06618963
- Testing
- Omalizumab Injection
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
GERD (Gastroesophageal Reflux Disease)
Study to Evaluate the Effect of Food on the Pharmacokinetics and Pharmacodynamics Characteristics in Healthy Adult Volunteers
A Randomized, Open-label, Oral in healthy volunteers
- Trial name
- NCT07364838
- Testing
- DW4421
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
The Study Goal is to Assess the Introduction of Sustainable Family Planning/Reproductive Health Information and Services Through, Land O' Lakes-supported Dairy Cooperatives
Family Planning Through Dairy Cooperatives
This observational study will assess a model for providing family planning through quarterly events organized by dairy cooperatives supported by Land O'Lakes in Kenya.
- Trial name
- NCT01226433
- Where
- Kenya
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- FHI 360
Food Intolerance, Celiac Disease
"Gluten Friendly" Treatment in Celiac Disease
A PROSPECTIVE, double blind, placebo-controlled trial
- Trial name
- GLUFR (NCT03137862)
- Testing
- Gluten free bread, Gluten friendly bread 3g/day, Gluten friendly bread 6g/day
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Cystic Fibrosis
A Phase 1 Study to Investigate the Food Effect of Lumacaftor in Combination With Ivacaftor
This study is designed to investigate the effect of food on the relative bioavailability of 2 different strengths of fixed-dose combinations of lumacaftor and ivacaftor tablet formulations.
- Trial name
- NCT01899105
- Testing
- lumacaftor, ivacaftor
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Vertex Pharmaceuticals Incorporated
Adherence, Food Allergy
Encouraging Allergic Young Adults to Carry Epinephrine
Fifteen million Americans suffer from food allergies. Food allergies can be life threatening; the only known life-saving treatment is epinephrine.
- Trial name
- NCT02354729
- Testing
- Behavioral Economics
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Pain, Neuropathic Pain
A Clinical Study in Healthy Women Which Aims to Explore the Intestinal Uptake of Two Different Tablets of GRTA9906 Into the Body and the Effect of Food on it
The aim of this clinical study in healthy women is to explore the intestinal uptake (bioavailability) of two different tablets of GRTA9906 (formulations) into the body and the effect of food on it.
- Conditions
- Pain, Neuropathic Pain, Chronic Pain, Visceral Pain
- Trial name
- NCT03765801
- Testing
- GRTA9906 60 mg PR tablet, GRTA9906 60 mg IR capsule
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Diabetes, Obesity
The Effect of Dairy and Non-dairy Alternatives on Satiety and Post-meal Glycemia in Healthy Young Adults
This study investigates the effects of commercially-available dairy (1% cow's milk and yogurt beverage) and non-dairy alternatives (almond and soy beverages) on satiety and post-meal blood glucose.
- Trial name
- NCT02491814
- Testing
- 1% M.F. Milk, Yogurt Beverage, Soy Beverage
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Behavior, Eating
Menu to Meal (M2M) Menu Labeling Intervention Study
This study evaluates the impact of culturally tailored menu labeling interventions on psychosocial factors and ordering behavior among customers in two independently owned Hispanic restaurants in East-Central Texas.
- Trial name
- NCT07329452
- Testing
- Paper menu, Digital menu condition
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Ketosis, Diabetic
Exogenous Ketones in People With Type 1 Diabetes
The aim of this pilot study is to investigate the metabolic effects of exogenous ketone ester food supplements, by assessing the change in blood acid-base balance, and the level of blood beta-hydroxy-butyrate in people with type…
- Trial name
- NCT04487678
- Testing
- Ketone ester supplement
- Volunteers
- healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Food (Shrimp) Allergy
The Utility of Serum Tryptase in the Diagnosis of Shrimp- Induced Anaphylaxis
The purpose of this study was to investigate the utility of serum tryptase for the confirmation of shrimp-induced anaphylaxis.
- Trial name
- NCT01619605
- Testing
- shrimp challenge
- Where
- Thailand
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Allergy;Food, Allergy Wheat
Food Challenge With Barley Starch as Active Comparator
Aim of the present study is to verify in a double-blind placebo controlled food challenge (DBPCFC) test that highly purified barley starch ingredient do not cause allergic reaction in subjects most potential to get allergic…
- Trial name
- BALA (NCT03352856)
- Testing
- Barley starch, Maize starch
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lyckeby Starch AB
Irritable Bowel Disease
Effects of Fasting and Hydro Colon Therapy Plus Probiotics on GI Microbiota in Intolerances and Irritable Bowel Syndrome
Consequences of Colon Hydrotherapy plus probiotic intervention on composition of GI microbiota and well being are analysed in subjects claiming GI inconveniences due to Irritable Bowel Syndrome or food intolerances.
- Trial name
- MicFFGAH2013 (NCT02372201)
- Testing
- Hydro Colon Therapy plus probiotic
- Where
- Austria
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Food Allergy, Food Allergy in Infants
The Egg Up Trial - Testing a New Treatment Pathway for Infants With Newly Diagnosed Egg Allergy
The goal of this study is to test the safety and feasibility of a change in management approach for infants with newly diagnosed egg allergy.
- Trial name
- NCT06273605
- Testing
- Egg Ladder
- Where
- Australia
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Food Allergy, Early Allergen Introduction
Food Introduction for Risk Reduction, Support Tolerance: Behavioral Intervention for Toddler Eating Success
The goal of this clinical trial is to evaluate the feasibility, acceptability, perceived safety, and adherence outcomes of FIRST BITES (Food Introduction for Risk Reduction, Support Tolerance: Behavioral Intervention for Toddler…
- Trial name
- FIRST BITES (NCT07857057)
- Testing
- Education and Reminders/Supportive Communication, Education
- Where
- 3 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center