Clinical trials: Food Systems
Celiac Disease, Wheat Hypersensitivity
Changes in Intestinal Permeability 4 Hours After Gluten Challenge
This study evaluates why people with celiac disease and non-celiac gluten/wheat sensitivity develop rapid onset symptoms within hours of gluten exposure. Half of subjects will be given gluten and half will not.
- Conditions
- Celiac Disease, Wheat Hypersensitivity, Gluten Sensitivity, Gluten Enteropathy
- Trial name
- NCT03288831
- Testing
- Gluten
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Chronic Cholecystitis, Biliary Dyskinesia
Food-Effect, Single and Multiple Dose Pharmacokinetics, Safety and Tolerability Study of 4-MUST, 128 mg, Tablets in Healthy Volunteers
This open-label study will evaluate the effect of food on the bioavailability of a single dose of 4-MUST, tablets, 128 mg. Additionally, the study will assess the pharmacokinetics, safety, and tolerability of 4-MUST, tablets, 128…
- Trial name
- NCT07594977
- Testing
- 4-MUST
- Where
- Russia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Dysphagia
The Effect of Food Taste, Temperature, and Viscosity on Swallowing Efficiency
The purpose of this study is to evaluate the effect of taste on swallowing efficiency, to evaluate the effect of temperature on swallowing efficiency, and to evaluate the effect of viscosity on swallowing efficiency.
- Trial name
- NCT01270204
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Empathy, Food Allergy
Prevention and Management of Food Allergies
This pilot study will test the use of visual cues to engage food service workers in protecting patrons with food allergies. Food service workers from Philadelphia quick-service restaurants were recruited to participate in a…
- Trial name
- NCT02377284
- Testing
- Photograph
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Food Allergy, Food Intolerance
Relation Between Adverse Reactions to Food, Physical Performance and Health in a Mediterranean Population
Since the prevalence of adverse reactions to foodstuffs (ARFS) has been steadily increasing and has become an alarming health concern, the general objective of this study is to analyze the prevalence of ARFS in Spanish adults of…
- Conditions
- Food Allergy, Food Intolerance, Adverse Reaction to Food
- Trial name
- NCT05802017
- Testing
- Allergen-specific substitute diet
- Where
- Spain
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Growth & Development, Obesity
Effects of Infant Egg Consumption on Child Health and Cognition Development
The objective of this study is to examine how infant egg consumption (age of introduction and frequency of intake) influences physical growth, obesity, cardio-metabolic health, risk of food allergy, and cognition development in…
- Conditions
- Growth & Development, Obesity, Cardiovascular Risk Factor, Metabolic Syndrome
- Trial name
- NCT04345185
- Testing
- Infant egg consumption (i.e., age of introduction and frequency of intake)
- Where
- United States
- Volunteers
- 5,374 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
IgA Nephropathy
A Food-Effect Study of Budesonide Delayed Release Tablet (D23A) in Healthy Chinese Participants
The goal of this clinical trial is to evaluate the effect of food (a high-fat, high-calorie meal) on the PK of a single oral dose of budesonide delayed release tablet in healthy participants.
- Trial name
- NCT07897240
- Testing
- Budesonide delayed release tablet
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Triastek, lnc.
Contraception
Safety,Effectiveness and Acceptability of Sino-implant II in DR
A study to assess the contraceptive effectiveness of Sino-implant (II).
- Trial name
- NCT01594632
- Testing
- Jadelle, Sino-implant (II)
- Where
- Dominican Republic
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- FHI 360
Aging, Healthy Aging
Biological Effects in Consumers of Resveratrol-enriched Wine
The objective of this clinical trial is to compare the health conditions of the participating population before and after an intervention with Resveratrol enriched wine. The main questions it aims to answer are: 1.
- Conditions
- Aging, Healthy Aging, Sarcopenia, Obesity
- Trial name
- NCT05981053
- Testing
- Wine enriched with Resveratrol
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PINER Pastor Manfredi Winery
Diabetes Mellitus, Type 2
A Clinical Study to Assess the Effect of Food and Gender on the Pharmacokinetics of SRT2104 Administered as an Oral Suspension or Capsule Formulation to Normal Healthy Volunteers
The primary objective of this study is to assess the pharmacokinetic profile of a single 500 mg dose of SRT2104 administered as an oral suspension and a capsule formulation to normal healthy male and female volunteers in both the…
- Trial name
- NCT00938275
- Testing
- 0.5g SRT2104
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sirtris, a GSK Company
Alzheimer Disease
Phase 1 Study of OLX-07010 in Healthy Adult and Elderly Participants
This First-in-human (FIH) study will evaluate the safety, tolerability, and pharmacokinetics of the tau self-association inhibitor, OLX-07010 in single ascending doses (SAD) and multiple ascending doses (MAD) in healthy adults…
- Trial name
- NCT05696483
- Testing
- OLX-07010 Active
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Oligomerix, Inc
Military Operational Stress Reaction, Malnutrition (Calorie)
Physiological Response to Protein and Energy-enhanced Food Products During Winter Military Training
Soldiers commonly lose muscle mass during training and combat operations that produce large energy deficits (i.e., calories burned > calories consumed).
- Conditions
- Military Operational Stress Reaction, Malnutrition (Calorie), Weight Loss, Muscle Wasting
- Trial name
- NCT05210205
- Testing
- EAA, Energy Dense, Control
- Where
- Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Food Allergy
Early Introduction and Sustained Ingestion (EISI) Using Two Educational Opportunities in Infants
The objective of the study is to see whether early feeding of potentially allergic foods can be increased with educational materials alone or with educational materials and additional in-person support opportunities.
- Trial name
- NCT07321522
- Testing
- Education and Opportunities on Early Introduction, Clinician Supervised Feeding of Known Allergenic Food
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Stanford University
Nutrition, Food Selection
Front-of-Package Nutrition Labels
The goal of this study is to determine whether certain front-of-package food labeling systems improve the healthfulness of consumers' grocery selections.
- Conditions
- Nutrition, Food Selection, Food Preferences, Dietary Habits
- Trial name
- NCT06516627
- Testing
- Positive Labels, Spectrum Labels, FDA High In Labels
- Where
- United States
- Volunteers
- 6,002 people, healthy volunteers welcome
- Sponsor
- Harvard Pilgrim Health Care
Child Allergy, Food Allergy
Impact of an Educational Tool on Quality of Life and Anxiety in Parents of Children With Nut Allergy
The number of young children with food allergy, in particular with nut allergy, is increasing worldwide. A diagnosis of nut allergy can cause much anxiety in parents.
- Trial name
- NCT05458882
- Testing
- "living with food allergy" educational booklet
- Where
- Ireland
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Children's Health Ireland
Type 2 Diabetes
Blood Glucose Response to Highly Viscous Polysaccharide Enriched Biscuits in Healthy and Diabetic Subjects
Our objective was to test whether the highly viscous polysaccharide incorporated into the biscuit formulation would reduce the postprandial blood glucose response equally in healthy subjects and individuals with type 2 diabetes.
- Trial name
- NCT00728143
- Testing
- Highly viscous polysaccharide enriched biscuits
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Huntington Disease, Tardive Dyskinesia
Effect of Food on the Pharmacokinetics of LPM3770164 Sustained-release Tablets
This is a A single-center, randomized, open-label, two-dose, two-period, crossover trial was conducted to evaluate the effect of food on the Pharmacokinetic characteristics and safety of oral administration of LPM3770164…
- Trial name
- NCT06474650
- Testing
- LPM3770164 sustained release tablet
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Vasomotor System; Labile, Healthy Volunteer
A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Dose Escalation of GS1-144 Tablets and the Effects of Food on the Pharmacokinetics of GS1-144 in a Chinese Population
A Phase I clinical study evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple oral dose escalation of GS1-144 tablets and the effects of food on the pharmacokinetics of GS1-144 in a…
- Trial name
- NCT06385158
- Testing
- GS1-144 tablet
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Obesity, Diabetes
Effect of Yellow Pea Protein and Fibre Added to a High-carb Meal on Glycemic Response and Food Intake
The investigators hypothesized that consuming isolated yellow pea fibre or protein, alone to together, as part of a high-carbohydrate pasta meal, would reduce the blood glucose response to the meal compared to a meal without…
- Trial name
- NCT02015429
- Testing
- Pasta meal with added fractions or control with no fractions
- Where
- 2 sites in Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Food Allergy in Children
CBT Group Intervention for Children With Food Allergy and Anxiety
The research will design and evaluate a CBT based intervention to support children aged 11-17 with food allergies. The research on this population has shown that they can experience high levels of anxiety in management of their…
- Trial name
- NCT04770727
- Testing
- CBT workshop
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Surrey