Clinical trials: Foot/Ankle
Lower Limb Amputation at Ankle (Injury)
Comparing New Prothesis PROPRIO-FOOT® Versus Usual Prothesis Tasks Tibial Amputees
Evaluate a new porosthetic device in lower limb amputees.
- Trial name
- PROPRIO-FOOT (NCT02501408)
- Testing
- propriofoot prosthesis
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Popliteal Nerve Block, Foot Surgery
Effect of Ropivacaine During Popliteal Nerve Block in Foot and Ankle Surgery
With the increasing rise of outpatient surgery in orthopaedic procedures, the management of immediate postoperative pain has been a major topic investigated, with the use of a peripheral nerve block in combination with general…
- Conditions
- Popliteal Nerve Block, Foot Surgery, Ankle Surgery
- Trial name
- NCT04872322
- Testing
- Ropivacaine 0.5% Injectable Solution, Ropivacaine 0.25% Injectable Solution, Percocet Pill
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Ankle Arthritis, Arthritis Foot
The Use of a Dynamic Sustained Compression Intramedullary Nail for Tibiotalocalcaneal Arthrodesis
The purpose of this study is to determine the clinical efficacy of a novel sustained dynamic compression intramedullary nail for tibiotalocalcaneal (TTC) arthrodesis utilizing longitudinal weight-bearing computed tomographic…
- Trial name
- NCT04831645
- Testing
- DynaNail, Tibiotalocalcaneal Arthrodesis
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- MedShape, Inc
Aging Problems
Effects of Feet and Ankle Mobilization on Balance of Older Adults
This study aims to assess whether mobilization of the ankle and foot produces significant improvements in the balance of the elderly.
- Trial name
- FEET_BALANCE (NCT03092869)
- Testing
- Feet and Ankle Mobilization, Proprioceptive Training
- Where
- 2 sites in Spain
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Motion Capture, Foot and Ankle Joint
Markerless Motion Capture in Foot and Ankle Surgery
Proof of Concept: ROM measured by the markerless system compared to clinical examination using a goniometer and motion capture analysis.
- Conditions
- Motion Capture, Foot and Ankle Joint, AI
- Trial name
- ROM OpenCap (NCT07848282)
- Testing
- Markerless motion capture in foot and ankle surgery
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Menopause, Musculoskeletal Function
Foot and Ankle Strengthening Program to Improve Physical Function in Menopausal Women (FAMEX)
This randomized controlled trial will evaluate the effects of a 12-week foot and ankle strengthening program on physical function and health-related quality of life in menopausal women.
- Conditions
- Menopause, Musculoskeletal Function, Physical Function
- Trial name
- (FAMEX) (NCT07472205)
- Testing
- Foot and ankle exercise program
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Ankle Osteoarthritis, Flat Foot or Pes Planus
Orthotic Dose Response Study
This study will investigate the effect of foot orthoses on two common conditions (ankle osteoarthritis and symptomatic adult onset flat feet) by using a custom biplane X-ray system the group has developed to very accurately and…
- Trial name
- ODRS (NCT02629731)
- Testing
- custom orthoses with varying degrees of hindfoot posting
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Adult ALL, Healthy
Effects of Malleo-Lok Stiffness on Lower Limb Mechanics
The primary purpose of this research study is to determine if the stiffness of a commercially available ankle foot orthosis (Malleo-Lok, Bio-Mechanical Composites, Des Moines IA) impacts gait biomechanics and overall joint level…
- Trial name
- MalleoLokStiff (NCT04806100)
- Testing
- Malleo-Lok
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Healthy
Effect of a Newly Developed Brace on Foot Biomechanics.
For this interventional study the investigators will recruit a number of healthy volunteers with no symptoms in their lower limbs in the past 6 months and without history of foot and/or ankle conditions and/or surgery.
- Trial name
- NCT05819567
- Testing
- Newly Developed Ankle Brace
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Stress Fracture Foot, Stress Fracture Ankle
Intravenous Bisphosphonate in Stress Fracture Treatment -A Randomised Controlled Double Blinded Multicenter Trial
The effect of an intravenous bisphosphonate (zoledronic acid) on healing and symptoms of stress fractures that do not respond to conservative/conventional treatment within 6 months, will be investigated.
- Trial name
- NCT03576599
- Testing
- Zoledronic Acid Injectable Product
- Where
- Norway
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Plantar Fasciitis, Flatfoot
Foot and Ankle Range of Motion (Stretching) Apparatus
Range of motion at ankle joint and subtalar joint will be assessed before and after utilization of ARM device. The changes in range of motion will be recorded and compared to literature.
- Conditions
- Plantar Fasciitis, Flatfoot, Calcaneus Fractures
- Trial name
- NCT00527748
- Testing
- Non-Measuring Ankle Exerciser
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Missouri-Columbia
Defect of Articular Cartilage, Degenerative Joint Disease of Ankle and/or Foot
Efficacy and Safety of Chondron (Autologus Chondrocyte) in Patients With Cartilage Defects in Their Ankle
The objective of this study is to evaluate the efficacy and safety of Chondron (Autologus Chondrocyte) in patients with cartilage defects in their ankle for 18 months
- Conditions
- Defect of Articular Cartilage, Degenerative Joint Disease of Ankle and/or Foot, Ankle (Ligaments); Instability, Familial
- Trial name
- NCT02537067
- Testing
- CHONDRON
- Where
- 2 sites in South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Spastic Cerebral Palsy (sCP), Acquired Brain Injury
Impact of AFOs on the GMF of Children With CP or ABI
Children with cerebral palsy (CP) or an acquired brain injury (ABI) are often prescribed ankle-foot orthoses (AFOs) to correct impairments of muscles and/or to prevent contractures and bony deformities.
- Trial name
- NCT06930963
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke
Smart Ankle-Foot Orthosis to Improve Stroke Outcomes: Smart AFO
The Smart Ankle-Foot Orthosis (Smart AFO) system is an investigational system that combines a diagnostic ankle-foot orthosis with a mobile application to assist clinicians in optimizing an AFO user's gait by adjusting AFO…
- Trial name
- NCT05619484
- Testing
- Smart AFO
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Orthocare Innovations, LLC
Arthrosis, Unspecified, Ankle and Foot
Protracted Effect of the Ultrasound-guided Saphenous Block
This study focuses on optimizing the postoperative pain treatment after major foot and ankle surgery by prolonging the duration of the ultrasound-guided saphenous block.
- Trial name
- PEUSB (NCT02346110)
- Testing
- Bupivacaine-adrenaline, Dexamethasone, Sodium chloride
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Healthy
The Effect of Wearing the 'Nike Free'Shoe on Isokinetic Muscle Strength of Foot and Ankle and on Proprioception.
To evaluate the effect of wearing the 'Nike Free'Shoe on isokinetic muscle strength of foot and ankle and on proprioception the following protocol will be used.
- Trial name
- NCT00389662
- Testing
- Wearing the "Nike Free" shoe
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Ghent
Transtibial Amputation - Unilateral
Comparison of Various Prosthetic Foot-Ankle Mechanisms
In summary, subjects will be asked to wear a number of sensors and use different ankle-foot prostheses in place of their customary prosthesis.
- Trial name
- NCT05964855
- Testing
- MIT Variable Stiffness Prosthesis v1, MIT Variable Equilibrium Angle Prosthesis v1, MIT Sliding Beam Passive Prosthesis
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts Institute of Technology
Orthopedic Procedures
Minimum Anaesthesia Concentration of Lidocaine Required for Sciatic Popliteal Block
using a biased-coin design up-down sequential method, different concentration of lidocaine will be used for popliteal block After 45 successful block (positive response), the data will be used to calculate the minimum lidocaine…
- Trial name
- NCT03613974
- Testing
- Lidocaine
- Volunteers
- 50 people
- Sponsor
- Healthpoint Hospital
Foot Drop, Acute Lymphoblastic Leukemia
The Effects of Ankle Foot Orthoses on Gait Efficiency in Children With Acute Lymphoblastic Leukemia and Foot Drop
This study is designed to see if children with acute lymphoblastic leukemia who have developed foot drop during treatment for their leukemia consume less oxygen when walking with or without an ankle brace designed to support…
- Trial name
- NCT01001390
- Testing
- AFO Device
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- St. Jude Children's Research Hospital
Flexible Flatfoot
The Effect of Different Exercises on Lower Extremity Performance in Flexible Flatfoot
In the study, the effects of two different strengthening exercises combined with short foot exercise on lower extremity functional performance and muscle strength will be examined and compared in adults aged 18-45 years with…
- Trial name
- NCT06482580
- Testing
- PNF exercise, Clam exercise, Short-foot exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University