Clinical trials: Foot
Joint Instability
Gait Adaptations to Passive Dynamic Ankle-Foot Orthosis Use
This study will collect information on the different ways that people walk, that is, their gait, when they use ankle braces. Patients will visit NIH on at least three and as many as nine separate occasions.
- Trial name
- NCT00115401
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Hallux Valgus
Diagnosis of Hallux Valgus by Using a Foot Pressure Platform as an Alternative to Radiological Images
Hallux Vagus is a common deformity which affects the first metatarsalphalangeal joint. The current diagnostic tool is using X-ray which is expensive and includes radiation exposure.
- Trial name
- NCT02676037
- Testing
- foot pressure plate form
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Dundee
Healthy
Influence of Foot Types on Collegiate Athletes
The purpose of the study is to assess whether high or low arch foot types influence the overall performance of the athlete.
- Trial name
- NCT05992129
- Testing
- foot exercise
- Where
- Colombia
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Universidad del Magdalena
Haemophilia, Arthropathy
Biomechanical Determinants and Patterns Associated to the Pathophysiological Cascade of Ankle Arthropathy in Children With Haemophilia: Non-invasive In-vivo Measurement of Foot Joints in Children With Haemophilia During Gait.
Haemophilia is a rare X chromosome-linked coagulation disorder resulting from a congenital deficiency or absence of circulating factor VIII (Haemophilia A) or factor IX (Haemophilia B).As a consequence, patients with haemophilia…
- Trial name
- 3DMKFM (NCT02229331)
- Testing
- Gait analysis
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hand, Foot and Mouth Disease (HFMD)
The Phase IVc of Inactivated Enterovirus 71 Vaccine (Human Diploid Cell)
Enterovirus 71 (EV71), a major pathogen causing hand-foot-and-mouth disease (HFMD) worldwide, is a member of the Human Enterovirus species A, family Picornaviridae.
- Trial name
- NCT03240744
- Testing
- Inactivated EV71 vaccine (human diploid cell, KMB-17)
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Spinal Cord Injury
Can Vibration Stimulation of the Foot Sole Activate Leg Muscles?
Participants will be asked to complete three different tests (standing, stepping and assisted walking) and will experience three different experimental conditions during each test.
- Trial name
- NCT02043106
- Testing
- plantar vibration
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Wilfrid Laurier University
Hand, Foot and Mouth Disease
Immunity and Safety of Inactivated Enterovirus 71 Vaccine Post-marketing Among Children Aged 6-35 Months in China
This study evaluates three batches consistency, immunity duration and safety of inactivated Enterovirus 71(EV-A71) vaccine(vero cell) post-marketing among children aged 6-35months in China.3000 subjects will be recruited in this…
- Trial name
- NCT03893747
- Testing
- The first batch of inactivated EV-A71 vaccine (vero cell) producted by 40 L reactor, The second batch of inactivated EV-A71 vaccine (vero cell) producted by 40 L reactor, The third batch of inactivated EV-A71 vaccine (vero cell) producted by 40 L reactor
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Healthy
Peak Impact Forces and Metabolic Cost During Mid-Forefoot Striking in Shod Versus Barefoot Runners
This experimental study will compare impact forces and metabolic cost in runners (N=20; ages 18-45 years, who already use a forefoot strike running gait) in two treadmill running test sessions (shod vs barefoot running)
- Trial name
- NCT01536171
- Testing
- running with normal running shoes and barefoot
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Lipedema, Hypermobility Syndrome (Disorder)
Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema
Lipedema is a chronic adipose tissue disorder that commonly leads to joint laxity, hypermobility, and functional limitations, yet its impact on foot morphology has not been systematically examined.
- Conditions
- Lipedema, Hypermobility Syndrome (Disorder), Pes Planus, Joint Hypermobility
- Trial name
- NCT07294014
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Marmara University
Patellofemoral Pain Syndrome
A Clinical Study in the Use of Orthotics in Treating Pain in the Front of the Knee
Musculoskeletal conditions account for the third leading cause of health systems expenditure in Australia. Patellofemoral pain syndrome or pain about the knee cap is such a condition often treated in primary care.
- Trial name
- NCT00118521
- Testing
- Foot Orthotics, Physiotherapy
- Where
- Australia
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Hallux Valgus, Pain
Effects of Hallux Valgus Deformity on Rear Foot Position, Pain, Function, and Quality of Life in Women
To investigate relationship between HV deformity and position of rearfoot joints, and its effects on the quality of life, pain, and related functional status in women with bilateral hallux valgus (HV).
- Trial name
- NCT01989338
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Hand, Foot and Mouth Disease
An Immunity Persistence Study of Enterovirus 71 Inactivated Vaccine (Vero Cell)
This is an open，observational and follow-up clinical trial based on the clinical trial of EV71 vaccine extended age group.The purpose of this study is to evaluate the immunity persistence of EV71 vaccine developed by Sinovac…
- Trial name
- NCT05397587
- Testing
- Experimental Vaccine, Control Vaccine
- Where
- China
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Hand, Foot and Mouth Disease
Study to Evaluate the Tolerance and Pharmacokinetics of Suramin Sodium
This is a randomized, double-blind, placebo-controlled, single-dose with three incremental doses, Phase 1 study to evaluate the tolerance and pharmacokinetics of suramin sodium for injection in Chinese healthy adults.
- Trial name
- NCT03804749
- Testing
- suramin sodium
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Healthy, Adults
Strength Measurement in Intrinsic Foot Muscles With Break and Make Tests
The human foot is a complex structure, which serves functions such as support and mobility. These functions are accomplished through the deformation of the arch, which is controlled by intrinsic and extrinsic foot muscles.
- Trial name
- NCT04307758
- Testing
- Muscle Strength Assesment-Make Test, Muscle Strength Assesment-Break Test
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Gazi University
Foot Ulcer, Diabetic
Pressure Alternating Shoes
The project is designed to develop and test Pressure Alternating Shoes (PAS), which will periodically off-load certain regions of the foot in order to prevent foot ulcers.
- Trial name
- PAS (NCT06026813)
- Testing
- test pressure alternating shoes
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hallux Valgus and Bunion
Epidemiology of Bunion and Risk Factors
Analysis of the collected data to determine: Prevalence. Risk factors. Radiological and clinical patterns and their association with specific risk factors Of Hallux Valgus
- Trial name
- NCT06335459
- Testing
- epidemiology
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Assiut University
Plantar Fasciitis of Both Feet
Customized Shoe-padding Orthotics for Plantar Fasciitis
While human body receives large external force or motions, minor injuries to the soft tissues will be produced and will lead to acute or chronic inflammation reactions.
- Trial name
- NCT03226288
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Operative Incision
Effect of Intraoperative Ankle Nerve Blocks on Postoperative Discharge in Patients Undergoing Orthopaedic Foot Surgery
Postoperative pain is an important clinical issue which negatively affects patient's satisfaction, delays discharge and repeated admission after discharge in orthopedic surgery.
- Trial name
- NCT03550677
- Testing
- general anesthesia, ankle block
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
Pregnant Women
Classic Foot Massage Applied to Preeclamptic Pregnants and Insomnia and Anxiety
Preeclampsia affects the sleep quality of pregnant women. With this study, it is expected that the sleep quality will be regulated by applying massage to pregnant women.
- Trial name
- NCT05231811
- Testing
- massage
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Firat University