Clinical trials: Foot
Intermetatarsal Bursitis, Morton Neuroma
US and MRI of the Forefoot: Intermetatarsal Bursitis or Morton's Neuroma
The aim of this study is to investigate the incidence of intermetatarsal bursitis and Morton's neuroma in patients with metatarsalgia (i.e. pain in the forefoot) and control subjects by diagnostic imaging with ultrasound and MRI.
- Conditions
- Intermetatarsal Bursitis, Morton Neuroma, Intermetatarsal Neuroma
- Trial name
- NCT05685160
- Testing
- MRI with contrast, Ultrasound
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis
Lateral Wedge Insole With Subtalar Strapping for Knee Osteoarthritis
This is a clinical study to evaluate the efficacy of a lateral wedge insole with subtalar strapping in knee osteoarthritis treatment.
- Trial name
- NCT01739296
- Testing
- Lateral wedge insole with subtalar strapping
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Hand, Foot and Mouth Disease (HFMD)
The Phase IVd of Inactivated Enterovirus 71 Vaccine
Enterovirus 71 (EV71), a major pathogen causing hand-foot-and-mouth disease (HFMD) worldwide, is a member of the Human Enterovirus species A, family Picornaviridae.
- Trial name
- NCT03296410
- Testing
- EV71 and two measles attenuated live vaccine, EV71 and attenuated Japanese encephalitis vaccine, two measles attenuated live vaccine
- Where
- China
- Volunteers
- 1,220 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Diabetic Foot, Peripheral Neuropathy With Type 2 Diabetes
The Effects of Different Exercises on Tissue Mechanics, Strength and Neuropathy Symptoms in Type 2 Diabetes Patients
To examine the effects of aerobic exercise and foot exercises in addition to aerobic exercise on lower extremity distal tissue mechanics, muscle strength and neuropathy symptoms in type 2 diabetics with peripheral neuropathy.
- Trial name
- NCT05422235
- Testing
- Routine Medical Treatment, Aerobic Exercise, Aerobic Exercise+ Foot-Related Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Critical Limb Ischemia
Validation of OxyVu for Assessing Level of Amputation With Comparison to Other Modalities
Correlation of(OxyVu) values to to ABI, TBP, and TCOM in patients scheduled for foot level amputation because of critical limb ischemia, infection, or tissue necrosis.
- Trial name
- LOA (NCT00767923)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- HyperMed
Diabetic Foot Ulcer, Diabetic Foot
A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot
The purpose of this clinical investigation is to assess performance of the Medaxis Debritom+™ and to collect subject outcome data in the treatment of diabetic foot ulcers (DFU) vs Standard sharp debridement.
- Trial name
- NCT04564443
- Testing
- Medaxis Debritom+, Sharp Surgical Debridement, Additional Outer Dressing Application
- Where
- 6 sites in United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Medaxis, LLC
Pain in Leg, Unspecified, Knee Sprain
Efficacy of Instrumental Chiropractic Treatment Using Activator Methods for Pain and Dysfunction in Juvenile Athletes
The goal of the study is to prove efficacy of instrumental chiropractic treatment for leg pain in juvenile athletes. A randomized placebo controlled clinical trial including juvenile athletes with functional impairment and pain…
- Trial name
- NCT01449994
- Testing
- Activator IV (Activator Methods Int. Phoenix, Arizona)
- Where
- Austria
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Foot Diseases, Myofascial Pain
Myofascial Induction Effects on Stabilometry Versus Sham Laser
The objective is to determine the effectiveness of myofascial induction effects on stabilometric variables. Forty healthy subjects will be recruited for a single blind clinical trial.
- Trial name
- NCT04628286
- Testing
- Myofascial Induction
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Aged
The Foot Posture and Falling Risk in Older People
This research will be conducted to examine the relationship between the foot postures and fall risks of elderly individuals living in nursing homes, to identify the factors that most affect the risk of falling, and to inform…
- Trial name
- NCT06153732
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Bahar Anaforoglu Külünkoglu
Lipedema, Hypermobility Syndrome (Disorder)
Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema
Lipedema is a chronic adipose tissue disorder that commonly leads to joint laxity, hypermobility, and functional limitations, yet its impact on foot morphology has not been systematically examined.
- Conditions
- Lipedema, Hypermobility Syndrome (Disorder), Pes Planus, Joint Hypermobility
- Trial name
- NCT07294014
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Marmara University
Crow's Feet Lines
A Phase 1/3 Clinical Trial to Evaluate the Safety and Efficacy of HUTOX Compared to Botox® in Subjects With Moderate to Severe Crow's Feet Lines
A Phase 1/3 Clinical Trial to Evaluate the Safety and Efficacy of HUTOX Compared to Botox® in Subjects With Moderate to Severe Crow's Feet Lines
- Trial name
- NCT04081402
- Testing
- HU-014, Botox Inj
- Where
- South Korea
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Huons Co., Ltd.
Hallux Valgus
Prospective, Multi-Center Clinical Evaluation of the Open Wedge Osteotomy and Low Profile Plate & Screw (LPS) System Compared to the Proximal Chevron Osteotomy for the Treatment of Hallux Valgus With an Increased Intermetatarsal Angle
Is there a difference in clinical outcome measures as assessed by the AOFAS, SF-36 and Visual Analogue Scale of adult patients with moderate to severe hallux valgus with increased intermetatarsal angles treated with a proximal…
- Trial name
- Hallux valgus (NCT01791634)
- Testing
- proximal chevron osteotomy, proximal open wedge osteotomy with LPS system
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Healthy, Ankle Foot Orthosis (AFO)
Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff
The primary purpose of this research study is to determine if forces within carbon fiber custom dynamic orthoses (CDOs) can be reliability assessed using Loadpad and Loadsol force measuring sensors (Novel GMBH, St. Paul, MN).
- Conditions
- Healthy, Ankle Foot Orthosis (AFO), Peripheral Neuropathy
- Trial name
- CuffForce (NCT06127264)
- Testing
- Carbon Fiber Custom Dynamic Orthosis (CDO)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Hallux Valgus
The Toe-spread-out Exercise in Patients With Hallux Valgus and Without the Deformity
The effectiveness of conservative treatment of hallux valgus deformity has not been sufficiently explored yet. The aim of this study was to assess the effect of the toe-spread-out exercise on the amplitude and frequency pattern…
- Trial name
- NCT03423498
- Testing
- toe-spread-out exercise
- Where
- Poland
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Nursing Education
Effects of Education With Jigsaw Technique on Diabetic Foot Risk Knowledge and Self-Efficacy in Nursing Students
The aim of this study is to evaluate the effects of education given with the jigsaw technique on the diabetic foot risk knowledge and self-efficacy in nursing students
- Trial name
- NCT06987006
- Testing
- Jigsaw education, Classical Education Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Foot Diseases, Myofascial Pain
Effects of the Myofascial Induction Technique Versus a Control Laser
The objective is to determine the effectiveness of myofascial Induction effects on plantar pressures variables. Forty healthy subjects will be recruited for a simple blind clinical trial.
- Trial name
- NCT04628299
- Testing
- Myofascial Induction
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Plantar Fasciosis, Achilles Tendinosis
Clinical Evaluation of Placement of Radiofrequency-based Plasma Microdebridement in the Treatment Algorithm for Foot and Ankle Tendinosis and Plantar Fasciosis
To determine the magnitude of improvement for pain and function symptoms over a two year period after enrollment into the registry study in patients presenting with chronic heel pain and receiving standard of care treatment.
- Trial name
- TOPAZ Registry (NCT00420875)
- Testing
- TOPAZ MicroDebrider
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- ArthroCare Corporation
Foot Ulcer Chronic, Skin Ulcer Venous Stasis Chronic
Effectiveness of Autologous Platelet Rich Plasma in the Treatment of Chronic Non-Healing Wounds
This investigation plans to initiate the healing of chronic wounds by providing a concentrated platelet and growth factor therapy directly to the wound site by topical delivery.
- Conditions
- Foot Ulcer Chronic, Skin Ulcer Venous Stasis Chronic, Pressure Ulcer
- Trial name
- NCT02307448
- Testing
- Platelet Rich Plasma, Standard of Care
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ACR Biologics, LLC
Healthy
Sex Differences in Morton's Extension Application on Plantar Pressure Distribution in Different Foot Regions in Female and Male Patients Without Deformities: A Pre-Post Test Study
The aim of this study is to simulate the orthopedic treatment called Morton's extension on non-deformed patients to check the different effects producted by sex in footprint.
- Trial name
- NCT06715904
- Testing
- Womens with Morton´s Extension
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Lower Extremity, Photoacoustic
Photoacoustic Tomography in Assessment of Lower Extremity Artery Disease
Lower extremity artery disease (LEAD) is characterized by low awareness rate and high missed diagnosis rate, leading to low treatment rate and high disabling mortality rate.
- Trial name
- NCT06579326
- Testing
- Photoacoustic imaging
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University