Clinical trials: Foot & Ankle
Flat Foot [Pes Planus] (Acquired), Unspecified Foot
Comparison of Exercise Effects in Individuals With Flatfoot
Flexible flatfoot deformity, also known as flexible pes planus, is a common pathological condition characterized by decreased medial longitudinal arch height, eversion of the calcaneus and abduction of the forefoot, especially…
- Trial name
- NCT06313125
- Testing
- 3-dimensional foot-ankle extension exercises, Clam exercise, Short-foot exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Cerebral Palsy, Ankle Foot Orthosis (AFO)
3D Printed Orthotics in Children Adolescents
PRINT is a prospective mixed methods study exploring the feasibility and acceptability of providing 3-D printed orthotics specifically an ankle foot orthosis (AFO) to children and adolescents with cerebral palsy.
- Trial name
- PRINT (NCT03770949)
- Testing
- 3-D Printed Orthotic (Ankle Foot Orthosis)
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- Barts & The London NHS Trust
Stroke, Foot Drop
Ankle Robot to Reduce Foot Drop in Stroke
Deficits in ankle control after stroke can lead to foot drop, resulting in inefficient, aberrant gait and an elevated falls risk.
- Trial name
- NCT02483676
- Testing
- Treadmill plus anklebot, Treadmill only
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- VA Office of Research and Development
Negative Pressure Wound Therapy, Vacuum Therapy
Negative Pressure Wound Therapy for Surgical Wounds of the Foot and Ankle
Prophylactic use of Negative Pressure Wound Therapy (NPWT) on surgical wounds following lower extremity orthopedic trauma to prevent infectious complications.
- Conditions
- Negative Pressure Wound Therapy, Vacuum Therapy, Closed Incisions
- Trial name
- NEWTON (NCT02739191)
- Testing
- PICO, Smith & Nephew
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- J.C. Goslings
Foot Injury, Foot Deformity
Comparing Clinical Outcomes Using Two Insole Manufacture Techniques
The main purpose of this study is to find out if scanning the foot using a 3D scanner influences the effectiveness of custom made insoles, compared to the more traditional approach of taking a foam-box impression cast of the…
- Conditions
- Foot Injury, Foot Deformity, Foot Sprain, Feet, Flat
- Trial name
- NCT05444192
- Testing
- CAD/CAM insoles
- Where
- United Kingdom
- Volunteers
- 114 people
- Sponsor
- NHS Greater Glasgow and Clyde
Adult ALL, Healthy
Effects of Malleo-Lok Stiffness on Lower Limb Mechanics
The primary purpose of this research study is to determine if the stiffness of a commercially available ankle foot orthosis (Malleo-Lok, Bio-Mechanical Composites, Des Moines IA) impacts gait biomechanics and overall joint level…
- Trial name
- MalleoLokStiff (NCT04806100)
- Testing
- Malleo-Lok
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Osteoarthritis of Multiple Joints of Ankle or Foot, Healthy
Effects of Opioids and NSAIDs on Sympathetic Nervous System and Vascular Function
Evaluation of the effect of different analgesic treatments (Tramadol, Paracetamol, Diclofenac) on sympathetic nerve activity, blood pressure, heart rate, heart rate, and vascular function in osteoarthritis patients and healthy…
- Trial name
- OPIOVASC (NCT03781544)
- Testing
- Tramadol, Paracetamol, Diclofenac
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Ankle Injuries, Foot Injuries
Ankle Trauma: an Emergency Nurse Assessment Study
The ankle and/or foot injuries incidence is high. Lateral ankle sprains are most common diagnosis, while fractures represent less than 15% of final diagnosis.
- Conditions
- Ankle Injuries, Foot Injuries, Diagnosis, Treatment
- Trial name
- ATENA (NCT04126837)
- Testing
- Diagnosis and treatment
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Grenoble
Ankle Fracture, Ankle Arthrodesis
Compression Therapy for Swelling Management Following Ankle Injury
After an injury or undergoing foot/ankle surgery, patients often experience swelling in the injured area. Under current standard of care, plaster casts are removed at six weeks and patients are put in a walking boot.
- Trial name
- NCT06772649
- Testing
- Compression sleeve
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Diabetic Neuropathy With Loss of Sensation, Foot and Ankle Muscle Weakness
Influence of Physical Therapy for Foot and Ankle in the Gait of Individuals With Diabetic Neuropathy
The hypothesis is that a physical therapy intervention for foot and ankle of diabetic neuropathic individuals would affect positively the way they walk, lowering the harmful forces that these segments receive, that are associated…
- Conditions
- Diabetic Neuropathy With Loss of Sensation, Foot and Ankle Muscle Weakness, Foot and Ankle Range of Movement Restriction
- Trial name
- NCT01207284
- Testing
- Physical Therapy
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- University of Sao Paulo General Hospital
Accidental Falls, Fall Due to Loss of Equilibrium
OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO
The investigators propose a randomized control trial to evaluate long term effects and effectiveness of Moore Balance Brace (MBB) ankle foot orthoses (AFO) in reducing risk of falling in older adults.
- Conditions
- Accidental Falls, Fall Due to Loss of Equilibrium, High Risk of Falls Due to Mobility Limitation, Diabetes
- Trial name
- NCT02819011
- Testing
- MBB AFO, Control
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Bijan Najafi, PhD
Lumbar Spine Instability, Balance
Relationship Between Foot-ankle Characteristics and Lumbopelvic Control, Balance and Physical Performance
It has been shown that foot and ankle postural disorders can alter the biomechanic of lower extremity and pelvis. This situation can affects balance, postural control and phsical performance of individual adversely.
- Conditions
- Lumbar Spine Instability, Balance, Physical Performance, Foot
- Trial name
- NCT03359083
- Testing
- Correlation
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Ankle Injuries, Foot Injuries and Disorders
Weight Change With Controlled Ankle Movement (CAM) Boot Use
The purpose of the study is to determine if patients wearing a CAM boot have a change in weight compared to patients who wear a CAM boot and are provided nutritional guidelines and perform upper body exercises.
- Conditions
- Ankle Injuries, Foot Injuries and Disorders, Body Weight Changes
- Trial name
- CAM (NCT05692401)
- Testing
- Nutrition and Exercise Instruction
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nell Blake, DPM
Osteoarthritis of Multiple Joints of Ankle or Foot
Agili-CTM Implant Performance Evaluation in the Treatment of Osteoarthritis of the Great Toe
The purpose of this study is to evaluate the performance of the Agili-CTM implant in the treatment of osteoarthritis of the Great Toe.
- Trial name
- NCT02831244
- Testing
- Agili-CTM
- Where
- 4 sites in Israel, Italy and 2 more
- Volunteers
- 20 people
- Sponsor
- Smith & Nephew, Inc.
Rheumatoid Arthritis
Can Musculoskeletal Ultrasound Predict Fall Risk in Rheumatoid Arthritis Patients?
Rheumatoid patients have higher fall risk than normal population. Several fall risk factors were studied. No previous study investigated the role of musculoskeletal ultrasound as a predictor of fall risk in rheumatoid arthritis.
- Trial name
- NCT04464096
- Testing
- non
- Where
- Egypt
- Volunteers
- 101 people
- Sponsor
- Assiut University
Ankle Disease, Ankle Injuries and Disorders
Dexmedetomidine Vs Dexamethasone in Popliteal Nerve Block
Effect of Perineural Dexmedetomidine vs. Dexamethasone on the duration of popliteal nerve block for Anesthesia After Pediatric ankle/foot surgery.
- Conditions
- Ankle Disease, Ankle Injuries and Disorders, Foot Injury, Foot Diseases
- Trial name
- NCT06304324
- Testing
- 0.9% Sodium chloride, 0.1mg/kg Dexamethasone, 0.05ug/kg Dexmedetomidine
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Fracture of Foot
The Role of Blood Flow Restriction Therapy in Postop Rehabilitation of Foot and Ankle Injuries
The purpose of the study is to determine the role of blood flow restriction (BFR) + neuromuscular electrical stimulation (NMES) in improving post-operative physical therapy and recovery after ankle fracture surgery.
- Trial name
- NCT05844280
- Testing
- BFR+NMES at therapeutic level, BFR+NMES at sub therapeutic level
- Sponsor
- University of Alabama at Birmingham
Arthrosis, Unspecified, Ankle and Foot
Protracted Effect of the Ultrasound-guided Saphenous Block
This study focuses on optimizing the postoperative pain treatment after major foot and ankle surgery by prolonging the duration of the ultrasound-guided saphenous block.
- Trial name
- PEUSB (NCT02346110)
- Testing
- Bupivacaine-adrenaline, Dexamethasone, Sodium chloride
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- University of Aarhus
Cerebral Palsy
Tuned Versus Untuned Ankle-foot Orthoses in Children and Adolescents With Cerebral Palsy
Cerebral palsy (CP) in children and adolescents is frequently accompanied by gait abnormalities. Ankle-foot orthoses (AFO) have been suggested to improve the gait pattern.
- Trial name
- AFO (NCT03547674)
- Testing
- barefoot, shoes only, untuned AFO with shoes
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University Hospital, Basel, Switzerland
Bone Marrow Edema
Subchondroplasty for Treatment of Bone Marrow Edema in the Foot and Ankle
The subchondroplasty procedure has been used to treat bone marrow edema mostly located in the periarticular region of the knee. In the past few years, it has expanded its use in the foot and ankle.
- Trial name
- NCT03921489
- Testing
- Subchondroplasty
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ellianne M. Nasser