Clinical trials: Foot Pathology
Colorectal Cancer, Metastases
S-1 Versus Capecitabine in the First Line Treatment of MCC Patients.
The study is a two-arm randomised phase III trial. Patients will be randomised to receive capecitabine (arm A) or S-1 (arm B). Bevacizumab may be added according to the choice of the investigator.
- Trial name
- SALTO (NCT01918852)
- Testing
- Capecitabine, Teysuno, Bevacizumab
- Where
- 24 sites in Netherlands
- Volunteers
- 161 people
- Sponsor
- Dutch Colorectal Cancer Group
Hemiplegic Patients
The Effectiveness of Radial Extracorporeal Shock Wave Therapy as Additional Treatment Modality for Spastic Equinus Deformity in Chronic Hemiplegic Patients
This is a prospective, double blinded randomized, placebo-controlled study that will be conducted on 112 adult ischemic or hemorrhagic hemiplegic stroke patients with calf muscles spasticity so as to evaluate the effectiveness of…
- Trial name
- NCT05615493
- Testing
- radial extracorporeal shock wave therapy
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Doaa Waseem Nada
Tinea Pedis, Athlete's Foot
A Study of Econazole Foam 1% in Athlete's Foot
This is a 6-week clinical study (4 weeks of treatment, once per day, plus a 2-week follow-up period) of a topical foam to treat athlete's foot.
- Trial name
- NCT00768599
- Testing
- Econazole Nitrate Cream 1%, Econazole Nitrate Foam 1%, Vehicle Foam
- Where
- 6 sites in United States
- Volunteers
- 135 people
- Sponsor
- AmDerma
Myocardial Infarction (MI)
Can Wearable Technology be Used to Predict Exercise Intensity
There is a knowledge gap in the literature around using watts to measure exercise intensity in walking and running, this is largely due to new technological developments.
- Trial name
- (CWTPEI) (NCT06871943)
- Testing
- Incremental Shuttle Walk Tests
- Volunteers
- 24 people
- Sponsor
- Keele University
Foot Injuries and Disorders
Nutritional Supplements and Foot Surgery
This is a prospective randomized trial wherein participants will be assigned to NutraHeal™, NutraHeal Plus™, or standard of care for 1 week prior to foot surgery and 3 weeks after surgery.
- Trial name
- NCT05522179
- Testing
- NutraHeal, NutraHeal Plus
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- NutraHeal
Critical Limb Ischemia, Peripheral Vascular Disease
Study of Remodulin in Patients With Critical Limb Ischemia With No Planned Revascularization Procedures
The purpose of this study is to assess and compare the safety of continuous and daily subcutaneous Remodulin therapy in patients with critical limb ischemia (CLI) with no planned vascular interventional procedures; and to…
- Conditions
- Critical Limb Ischemia, Peripheral Vascular Disease, Foot Ulcers, Rest Leg Pain
- Trial name
- NCT00060996
- Testing
- Remodulin® (treprostinil sodium) Injection
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- United Therapeutics
Plantar Fasciitis of Both Feet
Effect of Dry Needling Versus Kinesiology Taping in Patient With Plantar Fasciitis
A single-blinded randomized controlled trial was conducted at hamza hospital Lahore ,Lahore poly clinic over 9 months. A total of 60 participants aged 20-45 years with clinically diagnosed plantar fasciitis and identifiable…
- Trial name
- NCT07118397
- Testing
- dry needling, kinesiology taping
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Peripheral Vascular Disease, Ischemia
A Clinical Study Using Autologous Bone Marrow Stem Cell for Diabetes Related Vascular Complications
Stem cell therapy has been a new and effective therapy in recent years for diabetic foot.This study intends to establish an optimal clinical research program, and attempts to break the technical bottleneck in the stem cell…
- Conditions
- Peripheral Vascular Disease, Ischemia, Diabetic Foot
- Trial name
- NCT02796079
- Testing
- mesenchymal stem cells, saline
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Jie Shen
Fungal Infections, Tinea Pedis
Evaluate the Efficacy and Safety of Tolnaftate Cream in the Treatment of Patients With Fungal Infections
This is a study clinical, multicenter, Phase III trial, to evaluate the efficacy and safety of tolnaftate cream in the treatment of patients with fungal infections such as Tinea foot, Tinea and Tinea crural body.
- Conditions
- Fungal Infections, Tinea Pedis, Tinea Cruris, Tinea Corporis
- Trial name
- Tonaftato (NCT01105013)
- Testing
- Clotrimazole
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Laboratório Teuto Brasileiro S/A
Surgery
The Effect of Foot Reflexology on Patient Satisfaction, Pain, and Vital Signs After Abdominal Surgery
Reflexology practice is an effective method in pain control by stimulating the release of endorphins. The study was conducted to determine the effect of foot reflexology applied to patients undergoing abdominal surgery on pain…
- Trial name
- NCT05103163
- Testing
- Foot Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Gurkan Kapikiran
Diabetic Foot Ulcer (DFU), Diabetic Symmetrical Polyneuropathy
Comparative Study of Combination Treatment of Bionerv E+ Versus Vitamin B Complex in Treatment of Diabetic Polyneuropathy in Type 2 Diabetic Patients and Its Effect on Wound Healing
Diabetic symmetrical polyneuropathy (DSPN) is a common complication of diabetes that affects the nerves, especially in the legs and feet. It can cause pain, numbness, tingling, weakness, and loss of sensation.
- Trial name
- NCT07877948
- Testing
- Alpha-Lipoic Acid, Vitamin B1, Vitamin B6, Vitamin B12, Vitamin E, Vitamin B1, Vitamin B6, Vitamin B12
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- BREGO Life Sciences
Postoperative Pain, Foot Numbness
Ultrasound Guidance Versus Electrical Stimulation for Continuous Popliteal-Sciatic Nerve Blocks
Research study to determine if pain relief following foot and/or ankle surgery is influenced by the technique used to place perineural catheter.
- Trial name
- NCT00876681
- Testing
- Popliteal catheter placed via ultrasound or electrical stimulation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, San Diego
Tinea Pedis
Clinical Study to Evaluate the Therapeutic Equivalence of Ketoconazole Cream 2% in the Treatment of Tinea Pedis
Clinical Study to Evaluate the Therapeutic Equivalence of Ketoconazole Cream 2% in the Treatment of Tinea Pedis
- Trial name
- NCT03824912
- Testing
- Ketoconazole Cream 2%, Ketoconazole Cream 2% (G&W Laboratories Inc.)
- Where
- 9 sites in United States, Belize and 1 more
- Volunteers
- 831 people
- Sponsor
- Encube Ethicals Pvt. Ltd.
Rheumatoid Arthritis, Lymph Node Mass
Relationship Between the Activity of Rheumatoid Arthritis and Lymph Node Morphology and Lymphatics Drainage
To observe the relationship between the activity of rheumatoid arthritis and popliteal/epitrochlear lymph node morphology and the drainage of hand/foot superficial lymphatic vessels
- Conditions
- Rheumatoid Arthritis, Lymph Node Mass, Lymphatic Vessel; Dilatation
- Trial name
- NCT02876874
- Testing
- indocyanine green(ICG)
- Where
- 2 sites in China
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Post Hallux Valgus Repair Pain
TRAUMEEL S in Reducing Pain After Correction of Hallux Valgus-Clinical Trial
Hallux valgus is a common deformity of the big toe, defined as medial deflection of the first metatarsal bone along with lateral deflection of the first toe.
- Trial name
- NCT00279513
- Testing
- Traumeel S
- Where
- Israel
- Sponsor
- Shaare Zedek Medical Center
Stroke, Pain
MRP Verses PNF on Pain, Foot Drop, Gait and Functional Mobility in Hemiplegic Patients.
This single blinded randomized control study aimed to determine the comparative effectiveness of two rehabilitation approaches for improving pain, foot drop, gait, and functional mobility in patients with hemiplegia.
- Conditions
- Stroke, Pain, Gait, Drop Foot, Foot Drop
- Trial name
- CEMRA-PNF (NCT06539247)
- Testing
- Motor Relearning Program with Electrical Muscle Stimulation (MRA + EMS), Proprioceptive Neuromuscular Facilitation Technique with Electrical Muscle Stimulation (PNF + EMS)
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- University of Lahore
Surgical Wound, Diabetes
EO2 Oxygen Delivery To Study Success Rate of Surgically Closed Wounds
The investigators will test the efficacy of the novel oxygen diffusion dressing allows delivery tissue oxygenation via TransCu O2® Oxygen Delivery System for use in caring for patients with surgically closed wounds.
- Conditions
- Surgical Wound, Diabetes, Amputation Wound, Incision Wound
- Trial name
- NCT03960463
- Testing
- Transcu O2®
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Baylor College of Medicine
Diabetic Foot, Peripheral Arterial Disease
TEsting for Arterial Disease in Diabetes (TrEAD) Study
This study will focus on determining; How accurate the test is in detecting poor circulation How it's accuracy compares to other commonly used tests, and Whether test results are linked to the chance of ulcer healing or…
- Conditions
- Diabetic Foot, Peripheral Arterial Disease, Diabetic Foot Ulcer, Peripheral Vascular Diseases
- Trial name
- NCT04058626
- Testing
- Transcutaneous pressure of oxygen (TcPO2), Toe Brachial Pressure Index (TBPI), Podiatry Ankle Duplex scan (PAD-scan)
- Where
- 2 sites in United Kingdom
- Volunteers
- 305 people
- Sponsor
- Imperial College Healthcare NHS Trust
Gait, Hemiplegic
Implanted Drop Foot Stimulator for Hemiparetic Patients
The aim of this study is to investigate the effects of the implantable drop foot stimulator "ActiGait" (Ottobock Health Care, Duderstadt, Germany) on gait in hemiparetic patients.
- Trial name
- NCT03447717
- Testing
- ActiGait
- Volunteers
- 10 people
- Sponsor
- Medical University of Vienna
Neonatal Hyperbilirubinemia
Foot Reflexology and Massage in Neonates Receiving Phototherapy
Neonatal hyperbilirubinemia is a common condition in newborns and is frequently treated with phototherapy. In addition to standard treatment, non-pharmacological interventions such as massage and foot reflexology may help reduce…
- Trial name
- NCT07610811
- Testing
- Foot Reflexology, Body Massage, Phototherapy Device
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Aydin Adnan Menderes University