Clinical trials: For Intervention
Hypertension, Non-Adherence, Patient
Telehealth Intervention for Improved Blood Pressure Control With Targeted Incentives
Hypertension is the leading risk factor for cardiovascular disease, global mortality, and ranks third among the causes of disability.
- Trial name
- NCT04075045
- Testing
- Wellth Smartphone App, Targeted Incentives, Non-Restricted Incentives
- Where
- 3 sites in United States
- Volunteers
- 97 people
- Sponsor
- Wellth Inc.
Peripheral Arterial Disease
Robotic-Assisted Peripheral Intervention for Peripheral Arterial Disease II
The purpose of this study is to evaluate the safety and performance of the CorPath 200 System in the remote delivery and manipulation of guidewires and rapid exchange catheters for use in percutaneous vascular interventions.
- Trial name
- RAPID II (NCT02742077)
- Testing
- Robotic-assisted peripheral vascular intervention
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Siemens Healthineers Endovascular Robotics, Inc.
Healthspan Improvement, Aging
Combination Gerotherapeutic Interventions for Healthspan Improvement
This study is a 90-day interventional, randomized, controlled pilot trial exploring multi-modal gerotherapies and their impact on longevity-related outcomes.
- Conditions
- Healthspan Improvement, Aging, Longevity
- Trial name
- NCT07475546
- Testing
- Rapamycin, Naltrexone, Metformin
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- AgelessRx
Colo-rectal Cancer
Therascreen® KRAS RGQ PCR Kit
An interventional, prospective IVD device study for the testing of DNA extracted from tumor tissue biopsy samples from patients with Colorectal Cancer (CRC) who have previously tested positive for the KRAS G12C mutation for…
- Trial name
- NCT05347745
- Testing
- therascreen® KRAS RGQ PCR Kit
- Where
- United Kingdom
- Volunteers
- 219 people
- Sponsor
- QIAGEN Gaithersburg, Inc
Risk Behavior, Cognitive Decline
Intervention on Modifiable Lifestyle Risk Factors for Dementia Prevention
The overarching aim is to develop and deploy a multidomain intervention delivered on a mobile application to help older adults reduce their risk for dementia by improving a set of modifiable lifestyle risk factors associated with…
- Trial name
- NCT04616794
- Testing
- Cognitive Engagement Group, Physical Activity Group, Diet Group
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- LuciLab
Nasal Airway Obstruction
Vivaer® Procedure for Treatment of Nasal Airway Obstruction Study
The purpose of this study is to compare the Vivaer procedure with radiofrequency (RF) energy to sham procedure for treatment of nasal airway obstruction (NAO).
- Trial name
- VATRAC (NCT04549545)
- Testing
- Vivaer ARC Stylus
- Where
- 12 sites in United States
- Volunteers
- 119 people
- Sponsor
- Aerin Medical
Atrial Fibrillation
Exploring the Efficacy of Once Daily Oral Rivaroxaban for Treatment of Thrombus in Left Atrial/Left Atrial Appendage in Subjects With Nonvalvular Atrial Fibrillation or Atrial Flutter
A study for subjects with atrial fibrillation (AF) or atrial flutter who are diagnosed with left atrial (LA) or left atrial appendage (LAA) thrombus. The study will assign subjects to rivaroxaban for treatment of thrombi.
- Trial name
- X-TRA (NCT01839357)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939)
- Where
- 31 sites in Bulgaria, France and 5 more
- Volunteers
- 60 people
- Sponsor
- Bayer
Coronary Artery Disease
PRECISION GRX Registry
To collect data on the routine patterns of use, safety and effectiveness, including the clinical and technical performance of the CorPath GRX System, in the delivery and manipulation of coronary guidewires and stent/balloon…
- Trial name
- NCT03278301
- Testing
- Robotic-assisted PCI
- Where
- 20 sites in United States, Brazil and 2 more
- Volunteers
- 952 people
- Sponsor
- Siemens Healthineers Endovascular Robotics, Inc.
Toe Joint Deformity
Observational Plan to Obtain Clinical Experience and Follow up Data on the Use of the ProxiFuse Hammer Toe Device
This is a multi-center, non-randomized, observational study to further evaluate the effectiveness and safety of the Proxifuse Hammer Toe Device when utilized for bone fixation. Approximately 4 US sites will participate.
- Trial name
- NCT02452671
- Where
- 5 sites in United States
- Volunteers
- 15 people
- Sponsor
- Cartiva, Inc.
Myocardial Infarction
A Trial Evaluating the Efficacy and Safety of Tenecteplase Together With Unfractionated Heparin Prior to Early Percutaneous Coronary Intervention (PCI) as Compared to Standard Primary PCI in Patients With Acute Myocardial Infarction (ASSENT 4 PCI)
To show whether addition of thrombolytic treatment by a single bolus injection of tenecteplase prior to early standard PCI (percutaneous coronary intervention) will improve the clinical outcome in patients with large acute…
- Trial name
- NCT00168792
- Testing
- Tenecteplase, PCI
- Where
- 176 sites in United States, Austria and 16 more
- Volunteers
- 1,671 people
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus
BLADE-PCI Trial (BLADE); PHASE IIB LIPOSOMAL ALENDRONATE STUDY
The main objective of this study is to assess the safety, efficacy and dose response of LABR-312 administered intravenously at the time of percutaneous coronary intervention (PCI) with a drug eluting stent in reducing restenosis…
- Trial name
- BLADE (NCT02645799)
- Testing
- LABR-312
- Where
- Israel
- Volunteers
- 270 people
- Sponsor
- BIOrest Ltd.
Clinical Competence, Medical Education
Intervention for Medical Student to Promote Cervical Cancer Screening Among Latinx Transmasculine Individuals
The team aims to test the effectiveness of an intervention to increase gender-affirming cervical cancer prevention behaviors targeted at medical students studying in Puerto Rico and Florida.
- Conditions
- Clinical Competence, Medical Education, Cervical Cancer Screening
- Trial name
- CC-Trained (NCT06844097)
- Testing
- Cervical Cancer Trans Inclusive Education (CC-TRAINED) Module, Disaster Preparedness Course
- Volunteers
- 60 people
- Sponsor
- Ponce Medical School Foundation, Inc.
Anxiety
Examining the Effectiveness of Wysa for Worry Program
The goal of this randomized controlled trial is to test for the effectiveness of Wysa's Worry computerized cognitive behaviour therapy (cCBT) program (a digital mental health intervention) in comparison to a digital app that…
- Trial name
- NCT05943418
- Testing
- Wysa for Worry, App-based Psychoeducation
- Volunteers
- 500 people
- Sponsor
- Wysa
Acute Ischemic Stroke
A Randomized, Controlled Trial to Evaluate the Safety and Effectiveness of the Route 92 Medical Reperfusion System (SUMMIT MAX)
The SUMMIT MAX study is a prospective, randomized, controlled, interventional clinical trial to evaluate the safety and effectiveness of the Route 92 Medical MonoPoint® Reperfusion System with the Hi Point 88 and HiPoint 70…
- Trial name
- NCT05018650
- Testing
- Route 92 Medical Reperfusion System
- Where
- 30 sites in United States, New Zealand
- Volunteers
- 250 people
- Sponsor
- Route 92 Medical, Inc.
Diabete Mellitus
FSL2 Post Approval Study for Pediatric and Young Adults Patients
This is a prospective, multi-center, non-randomized, single-arm study intended to characterize the safety of the FreeStyle Libre 2 Flash Glucose Monitoring System when used to manage diabetes in pediatric and young adult patient…
- Trial name
- NCT04959552
- Testing
- FreeStyle Libre 2
- Where
- 3 sites in United States
- Volunteers
- 550 people
- Sponsor
- Abbott Diabetes Care
Acute Anterior Myocardial Infarction
Rapid Intravascular Cooling in Myocardial Infarction as Adjunctive to Percutaneous Coronary Intervention
Rapid MI-ICE-Pilot is designed to demonstrate the safety and efficacy of the Celsius Control™ System (CCS) endovascular catheter to reduce the infarct size resulting from acute anterior myocardial infarction when used in…
- Trial name
- NCT00417638
- Testing
- Endovascular cooling by the Celsius Control System, Standard of care
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- ZOLL Circulation, Inc., USA
Presence of High Intracranial Pressure
An Evaluation of Non-invasive ICP Monitoring in Patients Undergoing Invasive ICP Monitoring Via an External Ventricular Drainage (EVD) Device
Invasive intracranial pressure (ICP) monitoring is highly effective, but involves risks. HS-1000 measures ICP non-invasively by assessing the acoustic properties of the patient's head.
- Trial name
- NCT02284217
- Testing
- EVD
- Where
- 7 sites in United States, Germany
- Volunteers
- 100 people
- Sponsor
- HeadSense Medical
Candidemia, Candidiasis, Invasive
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called Fosmanogepix) for the potential treatment of candidemia and/or invasive candidiasis, a life-threatening fungal infection…
- Trial name
- NCT05421858
- Testing
- Fosmanogepix, Caspofungin, Fluconazole
- Where
- 146 sites in United States, Argentina and 18 more
- Volunteers
- 450 people
- Sponsor
- Basilea Pharmaceutica
Renal Transplantation, Chronic Renal Allograft Failure
Tacrolimus as Secondary Intervention vs. Continuation of Cyclosporine in Renal Transplant Patients With Chronic Renal Allograft Failure (CRAF)
The purpose of this study is to compare renal transplant recipients on cyclosporine maintenance therapy vs. those converted to tacrolimus-based immunosuppression with respect to renal outcomes.
- Trial name
- NCT00637143
- Testing
- Tacrolimus, Cyclosporine
- Where
- 13 sites in Canada
- Volunteers
- 107 people
- Sponsor
- Astellas Pharma Inc
Oncology, Interventional Radiology
Clinical Evaluation of an Augmented Reality Intraprocedural Needle Guidance Platform for Soft Tissue Biopsy
This clinical feasibility evaluation is intended to further characterize and quantify the potential benefits of the FDA-cleared XR90 Augmented Reality (AR )imaging and guidance platform utilization in percutaneous soft tissue…
- Conditions
- Oncology, Interventional Radiology, Liver Carcinoma, Renal Carcinoma
- Trial name
- NCT07046832
- Testing
- Augmented Reality Guided Biopsy, Ultrasound Guided Biopsy
- Where
- 3 sites in United States
- Volunteers
- 104 people
- Sponsor
- MediView XR, Inc.
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