Clinical trials: For Intervention
Post Traumatic Stress Disorder, Problem Drinking
Tools for Health and Resilience Implemented After Violence Exposure (Project THRIVE)
Sexual assault victimization is a common and particularly harmful form of trauma that is associated with increased risk for high-risk drinking and other conditions of public health concern, such as PTSD.
- Trial name
- NCT03703258
- Testing
- App-based intervention
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Washington
Hemorrhoids
Comparison Study of Surgical Staplers for the Treatment of Hemorrhoids
The purpose of this study is to demonstrate that the Covidien EEA™ Hemorrhoid and Prolapse Stapling Set for the treatment of hemorrhoids is non-inferior to the competitor device based on the primary endpoint.
- Trial name
- HEMOSTASIS (NCT01306877)
- Testing
- EEA Hemorrhoid and Prolapse Stapling Set, Endosurgery Proximate PPH03 Stapling Set
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Medtronic - MITG
HIV Infections, Pre-exposure Prophylaxis
PrEP Readiness Interventions for Supporting Motivation
The overarching goal of this formative research is to examine whether, and in what combination, contingency management (CM) and motivational interviewing (MI) can facilitate entry of stimulant-using men who have sex with men…
- Conditions
- HIV Infections, Pre-exposure Prophylaxis, Substance Use Disorders
- Trial name
- PRISM (NCT04205487)
- Testing
- Motivational Interviewing (MI), Contingency Management (CM)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Florida International University
Suicide, Psychosis
Cognitive Behavioral Suicide Prevention for Psychosis: Aim 2
Investigators will evaluate the feasibility and preliminary effectiveness of modified Cognitive Behavioral Suicide Prevention for psychosis (CBSPp) in comparison to services-as-usual (SAU) in a randomized controlled trial.
- Trial name
- NCT05345184
- Testing
- Cognitive Behavioral Suicide Prevention for psychosis (CBSPp), Services as Usual (SAU)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Michigan
Chronic Rhinitis
A Study of RhinAer ARC Stylus for Treating Chronic Rhinitis (RELIEF)
Post-market study to continue to evaluate the effectiveness of the RhinAer ARC Stylus for chronic rhinitis.
- Trial name
- RELIEF (NCT04614324)
- Testing
- RhinAer ARC Stylus
- Where
- 15 sites in United States, Germany
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Aerin Medical
Tinnitus
A CBT-based Internet Intervention for Adults With Tinnitus in the United Kingdom
The purpose of this study is to determine the feasibility and effectiveness of a CBT-based internet intervention for adults with tinnitus in the United Kingdom
- Trial name
- NCT02370810
- Testing
- CBT-based internet-intervention for tinnitus
- Where
- United Kingdom
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Interventional Vascular Conditions
Clinical Evaluation of the OEC Elite MD for Vascular Procedures at Hamilton General Hospital
The purpose of this study is to collect feedback on imaging guidance adequacy from physicians who use the OEC™ Elite CFD Mobile Fluoroscopy System-Motorized Configuration to perform surgical procedures for which the use of mobile…
- Trial name
- NCT03417713
- Testing
- Fluoroscopic imaging with the OEC Elite Device
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- GE Healthcare
Lung Cancer
Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer
This research study is evaluating a behavioral intervention designed to help people with advanced lung cancer manage dyspnea (i.e., breathlessness or shortness-of-breath).
- Trial name
- NCT03089125
- Testing
- Dyspnea Intervention, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 247 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer, Mammographic Density
Karolinska Interventional Study of Mammograhic Density (Karisma-1)
A feasibility study, randomising to either 10 or 20 mg of tamoxifen. The primary aim is to identify the time to mammographic density change and piloting the procedures.
- Trial name
- Karisma-1 (NCT04079517)
- Testing
- Tamoxifen
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Cancer
Building Family Caregiver Skills Using a Simulation-Based Intervention for Care of Cancer Patients
The purpose of this study is to learn whether an education and support program can help caregivers feel more confident in technical and communication skills needed to care for a person with cancer.
- Trial name
- NCT04055948
- Testing
- One-on-one support/educational sessions, Telephone booster contact
- Where
- 2 sites in United States
- Volunteers
- 484 people
- Sponsor
- Case Comprehensive Cancer Center
Retinopathy of Prematurity
Synergistic Pharmacologic Intervention for Prevention of ROP (SPIPROP Study)
Phase 2, open-label, randomized, multi-center studies in infants and premature infants are necessary to determine treatment and preventative strategies for ROP.
- Trial name
- SPIPROP (NCT02344225)
- Testing
- Caffeine citrate, Ibuprofen, Ketorolac
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- State University of New York - Downstate Medical Center
Opioid Use, Stimulant Use
THRIVE: Culturally AdapTed Harm Reduction Intervention
The goal of this study is to develop and test a culturally adapted harm reduction intervention among Black adults who misuse opioids and/or stimulants.
- Trial name
- NCT06609278
- Testing
- harm reduction intervention
- Where
- 3 sites in United States
- Volunteers
- 63 people
- Sponsor
- Brittany Miller-Roenigk
Lower Extremity Amputation
Weight Loss Intervention for Individuals With Lower Extremity Amputation
The purpose of this study is to pilot test a program to help overweight and obese individuals with a lower extremity amputation (LEA) lose weight and become more physically active.
- Trial name
- MOVE-LEAP (NCT02085785)
- Testing
- Coached group, Self-directed control group, Screened only
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- VA Office of Research and Development
Caregiver Distress, Job Stress
Caregiver Self-Management of Stress
Unpaid informal caregivers (CGs), such as family and friends, who are also employed may be at significant risk of experiencing burden and stress.
- Trial name
- Caregiver SOS (NCT04337021)
- Testing
- Caregiver SOS
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Psychotic Disorders
Mobile After-Care Intervention to Support Post-Hospital Transition (MACS)
This study examines the feasibility and acceptability of a mobile device-delivered app, called Mobile After-Care Support (MACS), to improve patients' coping and treatment adherence following a hospitalization related to their…
- Trial name
- MACS (NCT03769493)
- Testing
- Mobile After-Care Support (MACS) app
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Butler Hospital
Dementia, Alzheimer Disease
Efficacy Study of Kinto Care Coaching for Dementia Family Caregivers
The goal of this clinical trial is to evaluate Kinto's Care Coaching intervention for dementia caregivers. The main questions it aims to answer are: Does the intervention help caregivers to address their general caregiving goals…
- Conditions
- Dementia, Alzheimer Disease, Lewy Body Disease, Vascular Dementia
- Trial name
- NCT05916664
- Testing
- Kinto Care Coaching
- Where
- United States
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Kinto
Maternal Sepsis, Neonatal Sepsis
Smart Discharges for Mom & Baby
This study aims to build a predictive algorithm that identifies mother-newborn dyads most at risk of death or complications in the 6 weeks after birth.
- Trial name
- NCT05730387
- Testing
- Observational only
- Where
- Canada
- Volunteers
- 7,182 people
- Sponsor
- University of British Columbia
Malignant Neoplasm, Oral Pain
MOM's PAIN (Methylene Blue for Oral Mucositis' PAIN)
This phase II trial studies how well methylene blue works in treating patients with cancer and pain associated with oral mucositis. Methylene blue may relieve pain associated with oral mucositis.
- Conditions
- Malignant Neoplasm, Oral Pain, Stomatitis
- Trial name
- NCT03469284
- Testing
- Best Practice, Methylene Blue
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- M.D. Anderson Cancer Center
Weight Loss, Weight, Body
Sleep Goal-focused Online Access to Lifestyle Support
The overall goal of the study is to develop a novel weight loss intervention for postpartum people by providing strategies to improve sleep, diet, and physical activity behaviors.
- Trial name
- SGOALS (NCT05942326)
- Testing
- Sleep GOALS, Education
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Opioid-use Disorder, Opioid Use
PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Primary Care Providers
The objective of this research is to assess the effects of electronic health record (EHR)-based decision support tools on primary care provider (PCP) decision-making around pain treatment and opioid prescribing.
- Conditions
- Opioid-use Disorder, Opioid Use, Opioid Abuse
- Trial name
- PRINCE (NCT04601506)
- Testing
- Choice Architecture Nudge, PMP Integration & Nudge
- Where
- United States
- Volunteers
- 472 people
- Sponsor
- University of Minnesota
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