Clinical trials: For Oncologic Patients
Leukemia, Myelocytic, Acute
Comparison of Two Treatments in Intermediate and High-risk Acute Promyelocytic Leukemia (APL) Patients to Assess Efficacy in 1st Hematological Complete Remission and Molecular Remission
The study will compare the efficacy of the 2 treatments in intermediate and high-risk APL patients in achieving first hematological complete remission and molecular remission.
- Trial name
- NCT00962767
- Testing
- gemtuzumab ozogamicin, ATRA plus 6-MP and MTX
- Volunteers
- 168 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Leukemia, Leukemia, Chronic
Total Body Irradiation Treatments for Patients Treated at European Institute of Oncology
Patients eligible undergoing total body irradiation as candidates for bone marrow or peripheral stem cell transplant.
- Conditions
- Leukemia, Leukemia, Chronic, Leukemia, Acute, Lymphoma
- Trial name
- NCT06335277
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- European Institute of Oncology
Childhood Infratentorial Ependymoma, Childhood Supratentorial Ependymoma
Study of Tumor Samples From Patients With Ependymoma Treated on the Children's Oncology Group ACNS0121 Trial
This research trial studies tumor samples from patients with ependymoma treated on the Children Oncology Group ACNS0121 trial. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn…
- Conditions
- Childhood Infratentorial Ependymoma, Childhood Supratentorial Ependymoma, Newly Diagnosed Childhood Ependymoma
- Trial name
- NCT01407744
- Testing
- laboratory biomarker analysis
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Children's Oncology Group
PORTs/Peripheral IVs Complication Rates
Post-Marketing Study to Assess Complication Rates of Oncology Patients With Ports and Peripheral IVs
This study is to collect current information on complications rates of subjects undergoing chemotherapy administration through Ports and peripheral IVs.
- Trial name
- VEINSFORLIFE (NCT02792764)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- C. R. Bard
Stomatitis
Safety and Efficacy of CG53135-05 in the Prevention of Oral Mucositis in Patients Receiving Bone Marrow Transplant
CG53135-05, a recombinant human fibroblast growth factor-20 (rhFGF-20) protein, is under investigation for the prevention of oral mucositis.
- Trial name
- NCT00104065
- Testing
- CG53135-05, velafermin
- Where
- 9 sites in United States
- Sponsor
- CuraGen Corporation
Cancer, Pediatric Cancer
Massage Impact on Sleep in Pediatric Oncology
This study aims to determine the impact of massage therapy for pediatric patients receiving intensive chemotherapy or stem cell transplant (SCT).
- Conditions
- Cancer, Pediatric Cancer, Chemotherapy Effect, Acute Myeloid Leukemia
- Trial name
- NCT06892158
- Testing
- Massage therapy, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Children's Hospital of Philadelphia
Cancer Pain Self-management
Praxis Evaluation of a Pain Self-management Support Intervention for Oncology Patients: A Stepped Wedge Design Study
Background: Significant barriers to cancer pain management are patient-related. So far, cancer pain self-management support interventions have only been tested in strictly controlled settings of randomized controlled trials (RCT)…
- Trial name
- EvANtiPain (NCT02891785)
- Testing
- ANtiPain
- Where
- 3 sites in Austria
- Volunteers
- 153 people
- Sponsor
- University of Vienna
Neoplams, Physician-Patient Relations
One-Page Truth-Telling Aid for Cancer Disclosure
The goal of this clinical trial is to learn whether a one-page communication aid can improve communication between physicians and patients with cancer during cancer-related truth-telling consultations.
- Conditions
- Neoplams, Physician-Patient Relations, Communication Research, Disclosure
- Trial name
- NCT07730164
- Testing
- One-Page Truth-Telling Aid, Blank Sheet
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Chang Gung University
Cancer
A Prospective Registry to Enable Collection of Standardized Routine Care Oncology Patient Data
This is an observational registry for patients at participating oncology centers. The data collection includes but is not limited to baseline variables, treatments given and outcome data. Patient surveys are also included.
- Trial name
- NCT06877884
- Where
- 7 sites in United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- N-Power Medicine
Early-Stage Breast Cancer, Neoadjuvant Therapy
COGNITION: Genomics-Guided Precision Oncology in Early High-Risk Breast Cancer
The COGNITION diagnostic platform elucidates the biomarker profile of neoadjuvant chemotherapy-resistant residual bulk tumors in high risk early breast cancer patients.
- Trial name
- COGNITION (NCT05906407)
- Testing
- Genomic Profiling / Sequencing
- Where
- 12 sites in Germany
- Volunteers
- 2,000 people
- Sponsor
- German Cancer Research Center
Radiodermatitis, Breast Cancer
Photobiomodulation Therapy for the Prevention of Acute Radiodermatitis in Breast Cancer Patients Undergoing Radiotherapy
Radiodermatitis (RD), an inflammatory skin reaction, occurs in more than 90 percent of cancer patients treated with radiotherapy (RT). This is the result of the radiation causing damage to the epidermal basal skin stem cells.
- Trial name
- LABRA (NCT03924011)
- Testing
- Photobiomodulation therapy (PBMT)
- Where
- 2 sites in Belgium
- Volunteers
- 71 people
- Sponsor
- Hasselt University
Pediatric Oncology Patients With Risk for Infections
Swiss 2024 Continous Fever Monitoring in Pediatric Oncology Patients
In children and adolescents undergoing chemotherapy for cancer, fever in neutropenia (FN) is the most frequent potentially lethal complication of chemotherapy for cancer.
- Trial name
- NCT05940766
- Testing
- Automated fever alerts
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Prostate Cancer Patients, Sexual Dysfunctions
Dyadic STEP-SexPCare for Sexual Health in Chinese Prostate Cancer Survivors and Their Female Partners
This pilot feasibility randomized controlled trial will evaluate the feasibility, acceptability, safety, and preliminary effects of Dyadic STEP-SexPCare, a culturally tailored, nurse-led psychosexual programme for Hong Kong…
- Trial name
- STEP-SexPCare (NCT07829367)
- Testing
- Dyadic STEP-SexPCare, Standard Survivorship Care
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma
A Study of Bempegaldesleukin (NKTR-214: BEMPEG) in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib or Cabozantinib Monotherapy) for Advanced Metastatic Renal Cell Carcinoma (RCC)
The main purpose of this study is to compare the objective response rate (ORR) and overall survival (OS) of bempegaldesleukin (NKTR-214: BEMPEG) combined with nivolumab to that of tyrosine kinase inhibitor (TKI) monotherapy…
- Trial name
- NCT03729245
- Testing
- bempegaldesleukin, sunitinib, nivolumab
- Where
- 96 sites in United States, Argentina and 8 more
- Volunteers
- 623 people
- Sponsor
- Nektar Therapeutics
Breast Neoplasms, Colorectal Neoplasms
The Canadian/US Integrative Oncology Study
This study describes the survival outcomes of advanced stage breast, colorectal, ovarian and pancreatic cancer patients receiving advanced integrative oncology (AIO) treatment at participating North American integrative oncology…
- Conditions
- Breast Neoplasms, Colorectal Neoplasms, Pancreatic Neoplasms, Ovarian Neoplasms
- Trial name
- CUSIOS (NCT02494037)
- Where
- 12 sites in United States, Canada
- Volunteers
- 400 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Oncology
Automatized "Semi-Whole-Body"-MRI Protocol for Cancer Staging
The aims of this study are to evaluate the image quality and robustness of a whole-body MRI protocol by using an innovative partially automatic algorithm (DOT engine), that automatically optimizes protocol parameters depending on…
- Trial name
- NCT03648619
- Testing
- Semi whole-body MRI
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Kantonsspital Baden
Cancer Therapy-Related Cardiac Dysfunction, Cardio-oncology
Structured Cardio-Oncology Rehabilitation for Cardiovascular Outcomes in Cancer Survivors
Cancer therapy-related cardiac dysfunction (CTRCD) has become a major cause of morbidity and mortality among cancer survivors. Although cardiac rehabilitation is recommended for cardiovascular disease prevention and management…
- Conditions
- Cancer Therapy-Related Cardiac Dysfunction, Cardio-oncology, Cancer Survivorship, Cardiovascular Risk
- Trial name
- CORE-CTRCD (NCT07622394)
- Testing
- Structured Cardio-Oncology Rehabilitation, Usual Care
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Xinjiang Medical University
Ovarian Cancer, Breast Cancer
Comprehensive Outcomes for After Cancer Health
This study intends to explore feasibility, acceptability, and outcomes related to the use of a digital health coaching intervention for individuals who have completed primary therapy for cancer.
- Conditions
- Ovarian Cancer, Breast Cancer, Lung Cancer, Gastric Cancer
- Trial name
- COACH (NCT05349227)
- Testing
- Digital Health Coaching Program, Fitbit
- Where
- 7 sites in United States
- Volunteers
- 625 people, healthy volunteers welcome
- Sponsor
- Pack Health
Cancer
Effects of Pet Therapy on Pain in Cancer Patients
This study will examine how animal-assisted therapy (AAT) affects aspects of pain. It will explore the possible benefits of the National Institutes of Health's AAT program on distress in cancer patients receiving pain and…
- Trial name
- NCT00431639
- Testing
- Animal Assisted Therapy
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
COVID-19, Cancer
Impact of the COVID-19 Infectious Epidemic on the Management of Oncology and Onco-hematology Patients and on the Psychological Consequences for Patients and Caregivers
This original study will assess the impact of the coronavirus health crisis on the management of patients undergoing medical treatment for cancer, in particularly on the modification of the hospital organization.
- Trial name
- COVIPACT (NCT04366154)
- Testing
- Questionnaire
- Where
- 2 sites in France
- Volunteers
- 809 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse