Clinical trials: For Oncologic Patients
Glioma, Recurrent Glioma
A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma, GHoST Trial
This clinical trial tests how well a digital treatment platform using a mobile application works for the delivery of home-based sequential therapy in patients with glioma.
- Conditions
- Glioma, Recurrent Glioma, Recurrent Glioblastoma
- Trial name
- NCT07074756
- Testing
- Chemotherapy, Computed Tomography, Internet-Based Intervention
- Where
- 2 sites in United States
- Volunteers
- 202 people
- Sponsor
- Mayo Clinic
Oncology
Phase I Prognostic Online (PIPO) Tool
Clinical trials are studies that test new treatments to see if they work and are safe for people with certain illnesses. Phase I clinical trials are the earliest stage of testing, where researchers give a new treatment to a small…
- Trial name
- PIPO (NCT07593053)
- Testing
- Immune checkpoint inhibitor, targeted agents
- Where
- Spain
- Volunteers
- 586 people
- Sponsor
- Vall d'Hebron Institute of Oncology
Cancer, Oncology
Intelligent Electric Bicycle for Health (VELIS) to Optimize the Return to Physical Activity for Oncology Patients
The purpose of this pilot study is to encourage oncology patients to continue effort retraining after their release from rehabilitation and recuperative care facilities with physical activity sessions and therapeutic education…
- Trial name
- NCT03340857
- Testing
- Intelligent electric bicycle (VELIS) sessions
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Fondation Audavie
Cancer, Dyspnea
Effects of a Specific Programme for the Recovery of Autonomy Plus Multimodal Physical Exercise in Oncology Patients With Dyspnoea
In recent years the survival of cancer patients has increased exponentially. But together with that survival, and due to the different oncological treatments, side effects have also increased significantly.
- Trial name
- NCT04766593
- Testing
- Oncological functional reeducation program
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Advanced Non-small Cell Lung Cancer (NSCLC), Recurrent or Metastatic Lung Cancer
Efficacy and Safety of Vorolanib Monotherapy As Third-line or Later Treatment for Advanced Non-small Cell Lung Cancer Patients: a Single-arm, Prospective, Open-label Phase II Clinical Study
This study evaluates the efficacy and safety of Vorolanib as monotherapy for advanced non-small cell lung cancer (NSCLC) patients receiving third-line or higher treatments.
- Conditions
- Advanced Non-small Cell Lung Cancer (NSCLC), Recurrent or Metastatic Lung Cancer, Third-line and Beyond Therapy, Angiogenesis Inhibition in Oncology
- Trial name
- Vigor (NCT06728852)
- Testing
- Administration of Vorolanib
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Li-kun Chen
Non-Hodgkin Lymphoma
PEARL Study: Improvement of Non-Hodgkin's Lymphoma Care
The main objective of the proposed study is to assess the effectiveness, feasibility and costs of a tailored strategy (developed in accordance with the barriers found and current practice) to improve care for patients with…
- Trial name
- NCT01562509
- Testing
- Implementation tools, Standard intervention
- Where
- Netherlands
- Volunteers
- 418 people
- Sponsor
- Radboud University Medical Center
Pediatric Cancer, Growth, Posttraumatic
Expressive Storytelling to Share Adolescents/Young Adults Cancer Stories
The purpose of this study is to test the feasibility, acceptability, and preliminary efficacy of an online expressive storytelling intervention for adolescents and young adults (AYA) with cancer. Specific Aim 1.
- Conditions
- Pediatric Cancer, Growth, Posttraumatic, Nurse-Patient Relations, Narrative Medicine
- Trial name
- ESSAY (NCT04855487)
- Testing
- Nurse-patient dyadic storytelling intervention
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Vanderbilt University
NSCLC (Advanced Non-small Cell Lung Cancer), NSCLC Stage IIIB~IV
Immune-Marker Platform for Patients With Advanced Lung Cancer
The goal of this observational study is to better understand how the immune system and certain tumor markers are linked to treatment response in patients with advanced non-small cell lung cancer (NSCLC) who receive…
- Conditions
- NSCLC (Advanced Non-small Cell Lung Cancer), NSCLC Stage IIIB~IV, NSCLC Non-small Cell Lung Cancer
- Trial name
- IMPALUX (NCT07150598)
- Where
- 2 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Technische Universität Dresden
Hematologic Diseases, Oncology Problem
Clinical Validation of a Dried Blood Spot Method for Analysis of Immunosuppressives and Antifungals in Pediatrics
This is a clincial validation study of a dried blood spot (DBS) method for the analysis of immunosuppressive and antifungal agents currently subject of therapeutic drug monitoring (TDM) in a pediatric population.
- Conditions
- Hematologic Diseases, Oncology Problem, Kidney Diseases, Transplantation Infection
- Trial name
- PROTECT (NCT02329808)
- Testing
- blood drawing
- Where
- Netherlands
- Volunteers
- 93 people
- Sponsor
- Radboud University Medical Center
Caregiver, Lobectomy Patient
Physical Activity Intervention Before and After Surgery in Older Adults With Lung Cancer and Their Family Caregivers
This trial studies whether a telephone-based physical activity intervention before and after lung cancer surgery can be provided to older patients and their caregivers.
- Conditions
- Caregiver, Lobectomy Patient, Lung Carcinoid Tumor, Lung Non-Small Cell Carcinoma
- Trial name
- NCT04085081
- Testing
- E-mail, Exercise Intervention, Quality-of-Life Assessment
- Volunteers
- healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Depression, Anxiety, Quality of Life
Investigating Whether Digital Acceptance Commitment Therapy Can Improve Mental Health for Hong Kong Cancer Patients Suffering From Depressive and Anxiety Symptoms.
The goal of this clinical trial is to validate the use of digital Acceptance and Commitment Therapy (Digi-ACT) in Hong Kong curative cancer patients with depressive and anxiety symptoms.
- Conditions
- Depression, Anxiety, Quality of Life, Cancer
- Trial name
- Digi-ACT (NCT05583851)
- Testing
- Acceptance and Commitment Therapy, Psychoeducation Active Control
- Volunteers
- 50 people
- Sponsor
- Hollo
Prostate Cancer
Feasibility of a Chemotherapy With Docetaxel-Prednisone for Castration-resistant Metastatic Prostate Cancer Elderly Patients
The objective of this study is to evaluate the feasibility of two different chemotherapy protocols with adjusted doses for patients aged 75 and over who often have medical problems other than prostate cancer.
- Trial name
- GERICO10 (NCT01254513)
- Testing
- Docetaxel every 3 weeks + Prednisone, Docetaxel weekly+ Prednisone
- Where
- 31 sites in France
- Volunteers
- 66 people
- Sponsor
- UNICANCER
Oncology, End Stage Cancer
VR for Symptom Control and Wellbeing
To investigate the effect that a Virtual Reality experience can have on patient symptoms and wellbeing for palliative care and oncology inpatients
- Conditions
- Oncology, End Stage Cancer, Palliative Care, Hematologic Malignancy
- Trial name
- NCT04821466
- Testing
- Virtual Reality Headset to provide a Virtual Reality Experience
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Royal Cornwall Hospitals Trust
Advanced Lung Cancer, Lung Metastasis
mRNA Vaccine for Advanced Lung Cancer and Pulmonary Metastases of Solid Tumors
BMD006 is an off-the-shelf antitumor mRNA vaccine targeting lung cancer and lung metastatic solid tumors. This is a single-center, open-label, dose-escalation clinical trial.
- Trial name
- NCT06928922
- Testing
- BMD006 monotherapy, BMD006 in combination with Immuno-Oncology (IO) therapy (Dose Escalation), BMD006 in combination with Immuno-Oncology (IO) therapy (Dose Expansion)
- Where
- China
- Volunteers
- 83 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Metastatic Colorectal Cancer
PRIME: Panitumumab Randomized Trial In Combination With Chemotherapy for Metastatic Colorectal Cancer to Determine Efficacy
The purpose of this study is to determine the treatment effect of panitumumab in combination with FOLFOX compared to FOLFOX alone as first line therapy for metastatic colorectal cancer
- Trial name
- NCT00364013
- Testing
- Panitumumab, FOLFOX regimen
- Volunteers
- 1,183 people
- Sponsor
- Amgen
Renal Cell Carcinoma
Transplantation of Reconstructed Renal Allografts Following Ex-Vivo Partial Nephrectomy
This study is designed to investigate a novel approach to offer more ESRD participants the benefits associated with renal transplantation by increasing the supply of available allografts
- Trial name
- NCT05725421
- Testing
- Donor Radical and Partial Nephrectomy, Kidney Transplantation, Laparoscopic Radical Nephrectomy
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Case Comprehensive Cancer Center
Oncology
Comparative Effectiveness of AKYNZEO® and Standard of Care (Including EMEND®) for the Prevention of Nausea and Vomiting (CINV) in Cancer Patients
This pragmatic trial addresses the clinical gap through the generation of evidence on the comparative effectiveness between AKYNZEO® and Standard of Care (SoC, including EMEND®) in the real-life setting
- Trial name
- NCT03831633
- Testing
- Akynzeo, Standard of Care
- Where
- France
- Volunteers
- 426 people
- Sponsor
- VIFORFRANCE
Serious Adverse Events, Patient Safety
Chemokeyp: A Feasibility Study for Realtime Safety Data-Capture for Potential Serious Adverse Drug Events
Chemokeyp is a feasibility study testing a secure ED-Oncology interface for patients receiving chemotherapy who may present to unscheduled care with possible treatment-related complications.
- Conditions
- Serious Adverse Events, Patient Safety, Pharmacovigilance, Oncology
- Trial name
- NCT07592234
- Where
- Ireland
- Volunteers
- 100 people
- Sponsor
- St Vincent's University Hospital, Ireland
Postoperative Delirium
The Role of Remazolam in Reducing the Incidence of Postoperative Delirium in Elderly Patients
This study is a prospective, randomized, controlled trial.The selected patients were randomly divided into remazolam general anesthesia group and propofol + midazolam general anesthesia control group according to computer…
- Trial name
- NCT05466279
- Testing
- remazolam, Propofol, Midazolam
- Where
- China
- Volunteers
- 131 people
- Sponsor
- Fang Jun
Inappropriate Prescribing, Clinical Oncology
Enhancement of the Prediction of Chemotherapy Prescribing Errors for Oncology Patients
It is a cross-sectional study examining a random sample of in- and out-patients, with proven malignant disease receiving chemotherapy, over a period of 6 months from the start of the study who visit the Oncology department, Ain…
- Trial name
- NCT02435290
- Testing
- determine the incidence , type , and severity of prescribing errors in the oncology department
- Volunteers
- 500 people
- Sponsor
- hadeer ehab