Clinical trials: For Oncologic Patients
Cancer
The National Oncologic PET Registry
The Centers for Medicare \& Medicaid Services (CMS), as the Federal agency that administers the Medicare program, only pays for positron emission tomography (PET) scans in patients with cancer for certain reasons and for certain…
- Trial name
- NOPR (NCT00868582)
- Testing
- PET scanning in cancer
- Where
- United States
- Volunteers
- 333,000 people
- Sponsor
- American College of Radiology Imaging Network
Amputation
Target Muscle Re-innervation and Regenerative Peripheral Nerve Interfaces Alone and in Combination for the Treatment of Residual and Phantom Limb Pain in Cancer Patients Who Have Received an Amputation
This clinical trial evaluates two surgical techniques (targeted muscle re-innervation [TMR] and regenerative peripheral nerve interfaces [RPNI]) alone and in combination for the alleviation of chronic residual limb and phantom…
- Trial name
- NCT06840262
- Testing
- Questionnaire Administration, Regenerative Peripheral Nerve Interface Surgery, Targeted Muscle Reinnervation
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- M.D. Anderson Cancer Center
Confort, Older Adults With Cancer
Enhancing Patient Experience in Geriatric Oncology
Approximately 60% of new cancer diagnoses and 70% of cancer-related deaths occur in adults aged 65 years and older, a population frequently affected by multimorbidity, frailty, sensory impairment, and treatment-related symptom…
- Trial name
- NCT07671586
- Testing
- Comfort menu and cart implemented
- Where
- Brazil
- Volunteers
- 264 people
- Sponsor
- Hospital Sirio-Libanes
Head and Neck Cancer (H&N)
Screening Psychosocial Distress in Head and Neck Cancer
This prospective, multicenter study aims to assess the presence of psychosocial distress using the Distress Thermometer in patients treated for head and neck cancer at the initiation of their speech-language therapy.
- Trial name
- DEP-VADS-ORTHO (NCT07851818)
- Testing
- Psychosocial distress screening using the Distress Thermometer
- Volunteers
- 80 people
- Sponsor
- Hôpital NOVO
Oral Mucositis, Stomatitis
A Phase II Controlled Trial of Velafermin for Prevention of Oral Mucositis
CG53135-05 (velafermin), a recombinant human fibroblast growth factor-20 (rhFGF-20) protein, is under investigation for the prevention of oral mucositis.
- Trial name
- NCT00323518
- Testing
- velafermin
- Where
- 33 sites in United States
- Volunteers
- 390 people
- Sponsor
- CuraGen Corporation
Prostate Cancer
Pemetrexed as Second-Line Therapy in Treating Patients With Hormone Refractory Prostate Cancer
Docetaxel-based therapy has been shown to prolong survival as first-line therapy for patients with hormone refractory prostate cancer (HRPC), and has become the standard of care.
- Trial name
- NCT00216099
- Testing
- Pemetrexed, Folic Acid, Vitamin B12
- Where
- 15 sites in United States
- Volunteers
- 49 people
- Sponsor
- Christopher Sweeney, MBBS
Clostridium Difficile Infection, Hematologic Diseases
Vancomycin for C Difficile NAAT+/EIA- Hematology Oncology Patients
This study will randomized hematology oncology patients with active diarrhea and a NAAT positive/toxin EIA negative to either 14 days of oral vancomycin capsules or placebo.
- Conditions
- Clostridium Difficile Infection, Hematologic Diseases, Bone Marrow Transplant, Oncologic Disorders
- Trial name
- NCT03030248
- Testing
- Vancomycin Oral Capsule
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Medical College of Wisconsin
Digestive Cancer, Metastatic Colorectal Cancer
TARGETed Therapy Drug MONITOring in DIGestive Oncology
Targeted therapy drug monitoring in digestive oncology: Dosage of plasma levels of various multikinase inhibitors (MKI) in patients treated for advanced digestive cancer (gastrointestinal stromal tumor (GIST), metastatic…
- Conditions
- Digestive Cancer, Metastatic Colorectal Cancer, Hepatocellular Carcinoma, GIST
- Trial name
- TARGETMONITO (NCT05443087)
- Testing
- Blood sampling to build population pharmacokinetics model
- Where
- 29 sites in France
- Volunteers
- 330 people
- Sponsor
- UNICANCER
Cancer, Oncology
A Psycho-educational Intervention for Symptom Cluster Management
The purpose of this study is to develop, implement and undertake a preliminary evaluation of a psychoeducational intervention for managing a cancer-related symptom cluster including pain, fatigue and sleep disturbance experienced…
- Trial name
- NCT03332199
- Testing
- Psycho-educational intervention
- Where
- Vietnam
- Volunteers
- 102 people
- Sponsor
- Hanoi Medical University
Breast Neoplasms, Lung Neoplasms
Benchmarking Large Language Models Against Tumour Boards for Oncology Treatment Recommendations
BEACON (Benchmarking AI for Clinical Oncology decisioNmaking) is a prospective, multicentre, comparative, blinded, non-interventional benchmark comparing the treatment recommendations of six frontier large language models (LLMs)…
- Conditions
- Breast Neoplasms, Lung Neoplasms, Urologic Neoplasms, Prostatic Neoplasms
- Trial name
- BEACON (NCT07739121)
- Testing
- Multidisciplinary tumour boards, Frontier large language models
- Where
- 5 sites in France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer, Cardiotoxicity
Understanding CARdiac Events in Breast Cancer
In Ireland, over 3,000 patients are diagnosed with breast cancer annually, and 1 in 9 Irish women will be diagnosed with breast cancer in their lifetime.
- Conditions
- Breast Cancer, Cardiotoxicity, Cardiomyopathies, Chemotherapeutic Toxicity
- Trial name
- UCARE (NCT05921279)
- Where
- 4 sites in Ireland
- Volunteers
- 100 people
- Sponsor
- National University of Ireland, Galway, Ireland
Cancer
Evaluation of the Therapeutic Approach of Aromatherapy by Olfaction of Essential Oils in Association With Hypnosis in the Management of Patients Followed for Cancer
Patients having the following gestures (blood test, change of dressing for cancerous lesion and complete toilet in bed) will be identified by the team of the medical oncology department.
- Trial name
- HYPNO-AROMA (NCT05714995)
- Testing
- hypnosis, Hypnosis with aromatherapy
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Chemotherapy-induced Peripheral Neuropathy
A Study of Topical Pirenzepine or Placebo in Oncology Patients With Chemotherapy Induced Peripheral Neuropathy
This is a randomized, double-blind, placebo-controlled adaptive study of the safety, tolerability, and exploratory efficacy of once-daily topical WST-057 administered for up to 19 weeks (or up to 24 weeks for subjects who…
- Trial name
- NCT05488873
- Testing
- WST-057 Active
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- WinSanTor, Inc
Cancer
Geriatric and Oncologic Assessment Before Treatment
In a randomized controlled trial, the investigators wish to investigate, if oncologic treatment decision based on G8 screening followed by geriatric assessment and subsequent MDT, if needed, in older frail patients with…
- Trial name
- GOAT (NCT02671994)
- Testing
- G8 screening, Geriatric assessment
- Where
- Denmark
- Volunteers
- 114 people
- Sponsor
- Odense University Hospital
Cancer, Breast, Sports Physical Therapy
Physical Exercise Benefits for Cancer Patients
The purpose of the study was to analyze the effect of a synchronous-supervised online home-based group during a 6-month exercise program on physical fitness, body composition and adherence compared to an exercise recommendation…
- Trial name
- NCT06275321
- Testing
- Synchronous-supervised online home-based group, Exercise recommendation group
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universitat Jaume I
Uveal Melanoma
Early Integration of Supportive Care for Metastatic Uveal Melanoma Patients (EarlyTogether)
The study main objective is to assess whether the early introduction of supportive care demonstrates a benefit on patients' psychological care needs at 6 months (M6), versus oncological standard of care in patients with…
- Trial name
- EARLY TOGETHER (NCT04728113)
- Testing
- Supportive care visit with questionnaires, Oncological standard visit
- Where
- 2 sites in France
- Volunteers
- 162 people
- Sponsor
- Institut Curie
Clostridium Difficile, Hematologic Diseases
Oligosaccharide for Cdiff(+) Heme-onc Patients
Clostridium difficile causes ~453,000 infections and ~29,300 deaths per year in the US, making it the most common hospital acquired infection in the country. C.
- Trial name
- NCT03778606
- Testing
- Potato starch
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Medical College of Wisconsin
Prostatic Neoplasm
Active Surveillance or Radical Treatment for Newly Diagnosed Patients With a Localized, Low Risk, Prostate Cancer START
The purpose of the START project is to evaluate the acceptability, the safety and the cost-effectiveness of a population based program of active surveillance for patients newly diagnosed with a localized, low risk, prostate…
- Trial name
- START (NCT03348722)
- Testing
- Active surveillance, Radical prostatectomy, Radiotherapy
- Where
- Italy
- Volunteers
- 850 people
- Sponsor
- Rete Oncologica Piemonte, Valle d'Aosta
Wound Complication, Surgical Site Infection (SSI)
Prophylactic Subcutaneous Drainage After Gynecologic Oncology Midline Laparotomy
The goal of this clinical trial is to learn whether placing a small drain under the skin can help prevent wound problems after gynecologic oncology surgery in adult women with a thick layer of tissue under the skin.
- Conditions
- Wound Complication, Surgical Site Infection (SSI), Gynecologic Cancers
- Trial name
- SCDRAIN-GO (NCT07735962)
- Testing
- Prophylactic subcutaneous closed-suction drainage, Standard closure without subcutaneous drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 334 people
- Sponsor
- Mahmut Yassa
Metastatic Colorectal Cancer
PRIME: Panitumumab Randomized Trial In Combination With Chemotherapy for Metastatic Colorectal Cancer to Determine Efficacy
The purpose of this study is to determine the treatment effect of panitumumab in combination with FOLFOX compared to FOLFOX alone as first line therapy for metastatic colorectal cancer
- Trial name
- NCT00364013
- Testing
- Panitumumab, FOLFOX regimen
- Volunteers
- 1,183 people
- Sponsor
- Amgen