Clinical trials: For Oncologic Patients, open to volunteers
Oncologic Diseases
Financial Toxicity (FT) for Radiotherapy (RT) Patients in Italy: a yAIRO (Associazione Italiana Radioterapia e Ocologia Clinica) Multicenter Study
Non- profit, multicenter, prospective, observational study. The study aims to assess financial toxicity (FT) in patients undergoing radiotherapy for oncological diseases, assessed with a validated questionnaire (Patient Reported…
- Trial name
- FIT-RT (NCT07175350)
- Testing
- PROFFIT
- Where
- 7 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Valerio Nardone
Cancer
Pre-infusion Aerobic Cycling Exercise for CardioRespiratory Fitness in Cancer Patients
Background to this Research Patients who undergo cancer treatment involving chemotherapy or immunotherapy, can experience considerable reductions in their fitness levels.
- Trial name
- PACE-CRC (NCT07182773)
- Testing
- Exercise
- Where
- Ireland
- Volunteers
- 80 people
- Sponsor
- University of Dublin, Trinity College
Hypotension, Urologic Neoplasms
Skin Conductance for Predicting Spinal Anesthesia-Induced Hypotension in Geriatric Urologic Oncology Patients
Spinal anesthesia-induced hypotension is a common and clinically significant complication in elderly patients undergoing oncologic surgery.
- Conditions
- Hypotension, Urologic Neoplasms, Aged, Spinal Anesthesia
- Trial name
- NCT07481851
- Testing
- Skin Conductance Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Breast Cancer, Metastatic Breast Cancer
Generative AI Patient Education Module for Breast Oncology
This study evaluates the safety, accuracy, and impact of an artificial intelligence (AI) tool designed to support patient education in breast cancer care for breast oncology patients under selected physicians care within the…
- Conditions
- Breast Cancer, Metastatic Breast Cancer, Carcinoma of the Breast
- Trial name
- NCT07512271
- Testing
- Survey (Participant), OpenEvidence CareConnect, Survey (Provider)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Francisco
Non-small Cell Lung Cancer (NSCLC)
Analysis of Whole Exome and Transcriptome Sequencing to Identify Prognostic Biomarkers in Patients With Non-Small Cell Lung Cancer (NSCLC)
This is a non-interventional translational research study aiming to comprehensively characterize the genomic and transcriptomic landscape of patients with non-small cell lung cancer (NSCLC).
- Trial name
- EXPLORE (NCT07900581)
- Where
- 20 sites in Cyprus, Greece
- Volunteers
- 300 people
- Sponsor
- Hellenic Cooperative Oncology Group
Breast Cancer Metastatic
Evaluation of Somatostatin Receptor Expression in PET 68Ga-DOTATOC in Patients Followed for Metastatic Breast Cancer
DOTABREAST: Evaluation of Somatostatin Receptor Expression in PET 68Ga-DOTATOC in Patients Followed for Metastatic Breast Cancer This is a prospective, monocentric, non-controlled, non-randomized, open-label, interventional study.
- Trial name
- DOTABREAST (NCT06611891)
- Testing
- 68Ga-DOTATOC
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Grenoble
Neurological Cancer
Standard Follow-up Program Neuro-oncology Patients (SFP Neuro-Oncology)
Standardised evaluation of baseline data regarding tumor-, patient- and treatment-characteristics as well as follow-up data regarding tumor- and clinical-outcome of neuro-oncology patients treated with radical/curative…
- Trial name
- NCT06528912
- Testing
- Radiotherapy
- Where
- Netherlands
- Volunteers
- 10,000 people
- Sponsor
- University Medical Center Groningen
Localized Pancreatic Ductal Adenocarcinoma, Stage 0 Pancreatic Cancer AJCC v8
A Brief Psychological Intervention to Improve Emotional Well-Being During Neoadjuvant Therapy for Pancreatic Cancer
This clinical trial tests how well a psychosocial oncology intervention during neoadjuvant therapy works for patients with pancreatic cancer that has not spread to other parts of the body (localized).
- Conditions
- Localized Pancreatic Ductal Adenocarcinoma, Stage 0 Pancreatic Cancer AJCC v8, Stage I Pancreatic Cancer AJCC v8, Stage IIA Pancreatic Cancer AJCC v8
- Trial name
- NCT07124611
- Testing
- Interview, Nutritional Therapy, Physical Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Colorectal Carcinoma (CRC)
Patient-led Follow-up from Home After Surgery for Colorectal Carcinoma
The primary goal of the patient-led follow-up from home, is the improvement of quality of life and the reduction of stress in patients, while obtaining a more complete picture of their health status.
- Trial name
- PROMISE (NCT06613581)
- Testing
- Home-based follow-up
- Where
- 5 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- Erasmus Medical Center
Patient Satisfaction, Cancer
Patient Satisfaction Following Multidisciplinary Cancer Care Assessment in Day Hospital.
This study aims to evaluate patient satisfaction following a multidisciplinary "complex assessment" conducted in a Day Hospital setting at the Centre Hospitalier de Martigues.
- Conditions
- Patient Satisfaction, Cancer, Quality of Health Care
- Trial name
- EVAQSAP-HDJ-BC (NCT07560423)
- Testing
- Multidisciplinary Complex Assessment
- Where
- France
- Volunteers
- 309 people
- Sponsor
- Centre Hospitalier de Martigues
Non-small Cell Lung Cancer
Study of Pembrolizumab and Single Agent Chemotherapy as First Line Treatment for Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer With Eastern Cooperative Oncology Group (ECOG) Performance Status of 2
The purpose of this study is to understand if treatment with one chemotherapy medication combined with immune therapy (pembrolizumab) is tolerable and effective for patients with lung cancer and performance status of 2 (PS2)…
- Trial name
- NCT04297605
- Testing
- Pembrolizumab, Pemetrexed (Chemotherapy), Nab-paclitaxel (Chemotherapy)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Rochester
Primary Brain Tumor, Metastatic Brain Tumor
Belvarafenib for CNS Efficacy in Patients With BRAF-Altered Solid Tumors
This is a Phase 2, open-label, single-arm clinical study designed to evaluate the efficacy and safety of Belvarafenib in patients with BRAF-altered primary brain tumors (Cohort 1) and metastatic brain tumors (Cohort 2).
- Trial name
- NCT07688356
- Testing
- Belvarafenib
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Pediatric Cancer, Cancer-related Fatigue
Wearable Technology-Supported Exercise Program for Fatigue and Quality of Life in Pediatric Cancer Patients (WE-EX PedsCa)
Children and adolescents receiving cancer treatment often experience fatigue, reduced physical activity, and decreased quality of life.
- Conditions
- Pediatric Cancer, Cancer-related Fatigue, Quality of Life, Exercise
- Trial name
- WE-EX PedsCa (NCT07337681)
- Testing
- standart care, Wearable Technology-Supported Exercise Program
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Head and Neck Cancer (H&N), Cancer of the Head and Neck
Online Perioperative Education Program on Patient Satisfaction and Clinical Outcomes for Head and Neck Surgery
CareOrbit is a digital perioperative patient-education and care navigation platform developed by the St. Louis-based venture Total Orbit in collaboration with Washington University's CORTEX Business Incubator.
- Trial name
- NCT07848841
- Testing
- CareOrbit, Standard perioperative education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Cancer, NGS
Performance Indicators and Impact on the Care Pathway of Sequencing on the SeqOIA and AURAGEN (Seqogen) Platforms for Oncology Patients
As part of the French Genomic Medicine Plan 2025 (FGM), the SeqOIA and AURAGEN platforms were selected to perform high-throughput genomic sequencing.
- Conditions
- Cancer, NGS, Tumor, RARE DISEASE
- Trial name
- SONCO (NCT07147465)
- Where
- 3 sites in France
- Volunteers
- 3,149 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Nursing, Gynecological Cancers
Effects of a Self-Regulation Based E-MOTE Program Delivered Via an AI-Assisted Robot and Supported by Mobile Platforms for Newly Diagnosed Gynecologic Cancer Patients
To evaluate the effectiveness of the E-MOTE Emotional Care Program, delivered through the Kebbi robot and the LINE Official Account, for patients newly diagnosed with gynecologic cancer undergoing surgery.
- Conditions
- Nursing, Gynecological Cancers, Psycho-Oncology
- Trial name
- NCT07745478
- Testing
- E-MOTE group
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cancer, Emergencies
Pro-active Monitoring of Vital Signs in Oncology Patients Using a Smartwatch
The goal of this single center prospective observational study is to determine the effect of chemotherapy on (the change in) vital parameters.
- Trial name
- PROGRESS (NCT06680778)
- Testing
- Proactive Monitoring
- Where
- Netherlands
- Volunteers
- 175 people
- Sponsor
- Erasmus Medical Center
Colo-rectal Cancer
NURSE-led Geriatric Assessment in Older Colorectal Cancer Patients
Older colorectal cancer patients frequently present with frailty, comorbidity, and other age-related vulnerabilities that may affect treatment tolerance and outcomes.
- Trial name
- NURSE-GA (NCT07872787)
- Testing
- Nurse-led Geriatric Assessment
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Helse Stavanger HF
Solid Tumor, Solid Tumor, Adult
Adapting for Latinx Populations an Intervention That Involves Discussing and Sharing Patients' Health-Related Values
The purpose of this study is to translate and tailor for Latinx participants a program called Communicating with Oncology Nurses about Values from the Outset (CONVO).
- Conditions
- Solid Tumor, Solid Tumor, Adult, Solid Tumor, Unspecified, Adult
- Trial name
- NCT04942717
- Testing
- CONVO intervention
- Where
- 5 sites in United States
- Volunteers
- 234 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Oncologic Disease, Hematologic Diseases
Molecular Characterizazion and Biological Samples Centralisation of Patients Affected by Oncoematolofic Pathology
Currently, the molecular characterization of onco-hematological, onco-immunological and hematological diseases, at onset or in relapse, of patients with suspected diagnosis afferent to the CROP centers, is done through…
- Trial name
- NCT06304194
- Testing
- Analysis of biological samples
- Where
- 3 sites in Italy
- Volunteers
- 340 people
- Sponsor
- Meyer Children's Hospital IRCCS