Clinical trials: Former Smoker, active
Diabetes Mellitus, Cigarette Smoking
The Effectiveness of Smoking Cessation in Prediabetic Smokers
Existing literature investigating the impact of smoking cessation on new-onset diabetes mellitus (DM) risk is conflicting. Combing the need for smoking cessation and body weight self-management to prevent the progression of…
- Conditions
- Diabetes Mellitus, Cigarette Smoking, Prediabetes
- Trial name
- NCT01926041
- Testing
- Varenicline for tobacco smoking cessation, Individualized counseling about both smoking cessation and weight control techniques
- Where
- Taiwan
- Volunteers
- 589 people
- Sponsor
- National Taiwan University Hospital
Smoking Cessation, Substance-Related Disorders
Easy Access to Smoking Cessation for People Receiving Opioid Agonist Therapy Who Are Smoking Tobacco
Background: About 85% of those receiving opioid agonist therapy (OAT) for opioid dependence are smoking tobacco. Cigarette smoke lead to lunge diseases and cause illness and death within this group.
- Trial name
- BAReNikotin (NCT05290025)
- Testing
- Nicotine patch, Nicotine gum, Nicotine lozenge
- Where
- 2 sites in Norway
- Volunteers
- 266 people
- Sponsor
- Haukeland University Hospital
Lung Carcinoma
Feasibility of Cell-Free DNA Liquid Biopsy in Screening High-Risk Patients for Lung Cancer
This clinical trial investigates how practical and doable (feasibility) cell-free deoxyribonucleic acid (DNA) liquid biopsy is in screening high-risk patients for lung cancer.
- Trial name
- NCT05384769
- Testing
- Liquid Biopsy, Low Dose Computed Tomography of the Chest, Survey Administration
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Smoking, Pain
Pain and Smoking Study 2.0: A Randomized Clinical Trial of Smoking Cessation Among Veterans With Chronic Pain
PASS2 aims to expand upon the recently completed study (PASS intervention), which tested the telephone delivery of a cognitive behavioral intervention (CBI).
- Conditions
- Smoking, Pain, Smoking Cessation
- Trial name
- PASS2 (NCT06442514)
- Testing
- PASS2, Treatment as Usual
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- VA Office of Research and Development
HIV/AIDS, Nicotine Dependence
Optimizing Tobacco Use Treatment for PLWHA
The advent of anti-retroviral therapy (ART) for people living with HIV/AIDS (PLWHA) substantially improved life expectancy but has also led to the critical need to address modifiable risk factors associated with cancer and…
- Trial name
- HTO (NCT04176172)
- Testing
- Varenicline, Nicotine patch, Standard treatment
- Where
- 2 sites in United States
- Volunteers
- 340 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Lung Carcinoma
Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigarette Smokers
This clinical trial studies whether home-based respiratory muscle training (RMT) and aerobic exercise (AE) programs can be used to improve lung health in current and former cigarette smokers.
- Trial name
- NCT07553819
- Testing
- Accelerometry, Aerobic Exercise, Biospecimen Collection
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Smoking Cessation, Pregnancy
Preliminary Effectiveness of Enhanced Text Message + Incentives
This study is a preliminary evaluation of a smoking cessation intervention designed for pregnant women that combines text message support and financial incentives.
- Trial name
- NCT07420621
- Testing
- Text Messages, Incentives
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Kansas Medical Center
Smoking Cessation, Smoking Cessation Counselling
New Smoking Cessation Intervention in Primary Care - a Randomized Controlled Trial
Cigarette smoking remains the leading modifiable risk factor for lung cancer4 and 16 other types of cancer, as well as chronic cardiovascular and pulmonary diseases.
- Trial name
- NCT07900724
- Testing
- WillQuit App, Smoking cessation standard treatment,
- Where
- Norway
- Volunteers
- 620 people
- Sponsor
- Helse Nord-Trøndelag HF
Smoking Cessation, Veterans Health
Veteran Social Support for Enhancing Use of Smoking Cessation Treatment
This study is recruiting Veterans who currently smoke cigarettes and support persons who are nominated by the Veterans. The purpose of this study is to assist Veterans with smoking cessation by asking Veterans to choose a support…
- Trial name
- VAntage (NCT05868421)
- Testing
- Support Person Coaching Call, SP written materials, Written Smoking Cessation Materials
- Where
- United States
- Volunteers
- 2,376 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Tobacco Use Disorder, Mental Disorders
Effectiveness of Smoking Cessation Education
Smoking is an important psychosocial problem that concerns society. It is reported that 1.3 billion people use tobacco products in the world and approximately 6 million people lose their lives due to smoking every year.
- Conditions
- Tobacco Use Disorder, Mental Disorders, Smoking Cessation
- Trial name
- NCT06930547
- Testing
- Experimental
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzurum Technical University
Smoking
Evaluation of Lung Cancer CT Screening Performance Among Former and Current Smokers
Diagnostic performance of low-dose chest CT scan combined with lung-RADS classification (version 1.1) for lung cancer screening among former and current smokers.
- Trial name
- NCT05486455
- Testing
- Low-dose chest CT scan
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Hospital St. Joseph, Marseille, France
High-risk Lung Nodules
Immunoprevention for High-risk Lung Lesions
The main purpose of this study is to assess nadunolimab as an immunoprevention strategy for high-risk lung nodules in participants who are current or former tobacco smokers. The study may last up to 5 years for each participant.
- Trial name
- NCT07284485
- Testing
- Nadunolimab
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Robert Samstein
Cigarette Smoking-Related Carcinoma
A Smartphone Application (QuitBot) for the Improvement of Smoking Cessation Among American Indians and Alaska Natives, NAITIVE Trial
This clinical trial develops a chatbot smartphone application (app), QuitBot, and text messaging to help American Indians (AI) and Alaska Natives (AN) to quit smoking commercial tobacco (smoking cessation), and evaluates two…
- Trial name
- NCT06697496
- Testing
- QuitBot Smoking Cessation Chatbot Program, QuitBot Smoking Cessation Text Messaging Program, Survey Administration
- Where
- United States
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Pulmonary Disease, Chronic Obstructive
A Study to Assess the Efficacy and Safety of Co-administration of GSK3862995B With GSK5784283 in Adult Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
This study is for adult participants with moderate to severe Chronic Obstructive Pulmonary Disease (COPD) who continue to experience exacerbations despite standard of care triple therapy treatment.
- Trial name
- ALARMONY (NCT07915791)
- Testing
- GSK3862995B, GSK5784283
- Volunteers
- 279 people
- Sponsor
- GlaxoSmithKline
Lung Carcinoma
MUC1 Vaccine in Preventing Lung Cancer in Current and Former Smokers at High Risk for Lung Cancer
This pilot phase I trial studies the side effects and how well MUC1 peptide-Poly-ICLC vaccine works in preventing lung cancer in current and former smokers at high risk for lung cancer.
- Trial name
- NCT03300817
- Testing
- Laboratory Biomarker Analysis, MUC1 Peptide-Poly-ICLC Vaccine
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- National Cancer Institute (NCI)
Lung Diseases, Lung Cancer, Protection Against
Phase II Trial to Modulate Intermediate Endpoint Biomarkers in Former and Current Smokers
The purpose of this study is to find out if an investigational combination drug called Lovaza (made with fish oils)+Curcumin C3 Complex (made from a root called curcumin) can help reduce the size of lung nodules.
- Trial name
- NCT03598309
- Testing
- Curcumin C3 complex®, Lovaza®
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Smoking ( Cigarette)
Effectiveness of Brief Smoking Cessation Counselling in Pre-Anaesthesia Assessment Clinic
The goal of this clinical trial is to evaluate whether a brief, nurse-delivered smoking cessation intervention can increase pre-operative smoking abstinence and improve perioperative outcomes among adult elective surgical…
- Trial name
- NCT07505147
- Testing
- Nurse-led AWARD brief smoking cessation counselling with active referral and tailored perioperative booklet in the pre-anaesthetic assessment clinic, Usual pre-anaesthetic care without structured smoking cessation
- Where
- Hong Kong
- Volunteers
- 125 people
- Sponsor
- Pok Oi Hospital
Bronchial Dysplasia, Tobacco Smoking
Nivolumab for the Reversal of Squamous Dysplasia in High Risk Current and Former Smokers
The goal of this clinical research study is to determine whether the PD-1 inhibitor (Programmed cell death protein 1) nivolumab improves premalignant bronchial dysplastic lesions in subjects that are at high risk for the…
- Conditions
- Bronchial Dysplasia, Tobacco Smoking, History of Non-Small Cell Lung Cancer, History of Head and Neck Cancer
- Trial name
- NCT03347838
- Testing
- Nivolumab
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Colorado, Denver
Smoking Cessation
Smoking Cessation Intervention During Low Dose CT (LDCT) Screening for Lung Cancer
The goal of this clinical research study is to offer lung cancer screenings to smokers who want to change their smoking behaviors.
- Trial name
- NCT03059940
- Testing
- Questionnaires, Low Dose Computed Tomography Scan, Shared Decision Making + Video
- Where
- United States
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Former Smoker, Non-Smoker
Vaped Phenanthrene
Some people who used to smoke cigarettes continue to be at higher risk of developing lung cancer, even years after quitting. This study will look to see if a specific chemical, phenanthrene, is broken down in the lungs of former…
- Trial name
- NCT07134426
- Testing
- D10-phenanthrene
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota