Clinical trials: Fortification
Iron Deficiency (Without Anemia), B12 Deficiency Vitamin
Hydroponic Fortification and Dietary App Effect on Nutrients Level (Harvest)
Veganism and vegetarianism have clear benefits where they have a lower risk of many health issues. However, they also have a higher risk of nutrients and vitamin deficiency such as iron and vitamin B12.
- Trial name
- NCT05740462
- Testing
- Recipes consumption, Hydroponic unit
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Neurodevelopmental Disorders, Lactation
Iron Supplement Effect on Child Development
Objective: To evaluate the effect of Iron supplement with two different amounts (one in the higher limit and another in the lower limit of the suggested amount) according to the presence of mutations in the HFE gene in the…
- Trial name
- NCT02690675
- Testing
- Iron fortified formula milk
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Preterm, Very Low Birth Weight Infant
Weight Gain in Extremely Premature Infant With Targeted Versus Adjusted Fortification
Investigation about the effect on weight gain in extremely low birth weight preterm with individualized fortification, according to human milk analysis versus fortification adjusted according to urea serum concentration.
- Conditions
- Preterm, Very Low Birth Weight Infant, Feeding, Breast, Food, Fortified
- Trial name
- FORTIN (NCT04982133)
- Testing
- Protein supplementation based on plasma urea concentration every other week or human milk analysis on experiment
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Paz
Iron Deficiency Anemia
Assessment of the Bioavailability of Iron in Iron Fortified Bouillon Cubes in Healthy Nigerian Women
The prevalence of iron deficiency anemia is a wide spread problem in Africa and iron fortification can be an effective strategy to decrease this.
- Trial name
- NCT02815449
- Testing
- Meals prepared with iron fortified cube with Low stabilizer level, Meals prepared with iron fortified cube with Medium stabilizer level, Meals prepared with iron fortified cube with High stabilizer level
- Where
- Nigeria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Vitamin D Deficiency
The Effect of Vitamin D on Bone Accretion and Turn-Over in Young Girls
Objectives To evaluate the effect of increased vitamin D intake on vitamin D status, bone mass and bone turnover in young girls aged 12-13.
- Trial name
- NCT00267540
- Testing
- cholecalciferol (D3) (vitamin)
- Where
- Denmark
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Anemia
Reducing Anemia Through Food Fortification at Scale
Anemia is the most common form of malnutrition, affecting approximately 1.6 billion people world-wide. Most commonly caused by iron deficiency, its adverse effects include increased mortality (especially during childbirth)…
- Trial name
- NCT03573570
- Testing
- Fortified rice kernels
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Folate Deficiency, Iodine Deficiency
Acceptability and Nutritional Impact of Double-fortified Salt Containing Iodine and Folic Acid
The overarching objective of this two-phase project is to assess the effects of fortifying iodized salt with folic acid on improving women's folate status.
- Conditions
- Folate Deficiency, Iodine Deficiency, Anemia Macrocytic, Anemia Deficiency
- Trial name
- DFS-IoFA-2 (NCT06223854)
- Testing
- Iodized salt, Experimental: Iodized salt with lower-dose folic acid fortification, Experimental: Iodized salt with higher-dose folic acid fortification
- Where
- Ethiopia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Vitamin D Biofortification, Vitamin D Fortification
Vitamin D (Bio)Fortified Shopping Baskets to Improve Vitamin D Status
Vitamin D is essential for healthy bones, muscles, and immune function. It comes from food, supplements, and sunlight. There are two main forms; vitamin D2, found mainly in plant foods, and vitamin D3, which comes from animal…
- Conditions
- Vitamin D Biofortification, Vitamin D Fortification, Vitamin D Status
- Trial name
- NCT07349290
- Testing
- Vitamin D (bio)fortified food basket, Control food basket
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Zinc Deficiency
Water-based Zinc Efficacy Trial in Beninese Shool Children
The general objective of this study is to determine the effect of the daily consumption of zinc-fortified water provided by the LSF-filter on zinc status and diarrhea rates in school age children from rural areas characterized by…
- Trial name
- NCT01790321
- Testing
- LSF-filtering device
- Where
- Benin
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Prof. Michael B. Zimmermann
Periodontitis, Inflammation
Calcium-vitamin D & Periodontal Therapy for Improving Metabolic and Inflammatory Profile Among Pregnant Women
The improvement of maternal and child health remains a key issue in global health. Production and improved accessibility of healthy and nutrient-rich milk-based products could potentially tackle health and nutrition inequalities…
- Trial name
- IMPROVE (NCT03148483)
- Testing
- Early PT, Delayed PT, Fortified Milk
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Westminster
Older Adults
The Effects of Texture Modified Diets on Dietary Intake and Appetite Responses in Older Adults
This study aims to investigate the effects of equicaloric texture modified and regular meals that are either fortified with protein or not on dietary intake and satiety in older adults (65+) living in the United Kingdom (UK).
- Trial name
- NCT04521374
- Testing
- Preload meals that are solid or texture modified and are fortified with protein or not fortified with protein
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Reading
Healthy
Effect of Lutein in S-26 Gold On Growth And Safety
Study to determine if the addition of lutein to infant formula supports healthy growth and development in healthy full term infants.
- Trial name
- S-26 Gold L (NCT00913406)
- Testing
- Lutein fortification, Standard formula
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Iron Absorption
Iron Absorption From Iron Enriched Aspergillus Oryzae in Females Using Stable Isotope Methodology
The objective of this study was to compare the iron absorption from ferric pyrophosphate enriched Aspergillus oryzae (ASP-p) to commonly used ferric pyrophosphate (FePP) and ferrous sulfate (FeSO4) when fortified in chicken…
- Trial name
- NCT03586245
- Testing
- Ferric pyrophosphate, Aspiron, Ferrous sulfate
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Vitamin D Deficiency
Food-based Solutions for Optimal Vitamin D Nutrition and Health
This project aims at proving the efficacy and safety of food based solutions to prevent vitamin D deficiency in high risk populations of Caucasian and South Asian origin living in Denmark.
- Trial name
- ODIN_FOOD (NCT02631629)
- Testing
- Non-fortified foods, Fortified foods
- Where
- Denmark
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Technical University of Denmark
Iron-deficiency
Iron Absorption From Encapsulated Iron Sulphate in Microspheres
Food fortification has shown to be efficacious to alleviate the burden of micronutrient deficiencies. Ensuring the bioavailability of iron and maintaining the sensory quality and stability of the fortified food and other added…
- Trial name
- NCT03332602
- Testing
- free FeSO4, free FeSO4 and empty microspheres, free FeSO4 and hylauronic acid
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy
The Effect of Vitamin D Fortification of Bread and Milk in Danish Families
Approximately 200 families corresponding to 800 persons are included in the study. The study investigate the efficacy of vitamin D fortification of bread and milk on vitamin D status in serum.
- Trial name
- VitMaD (NCT01184716)
- Testing
- Vitamin D fortification
- Where
- Denmark
- Volunteers
- 782 people, healthy volunteers welcome
- Sponsor
- Technical University of Denmark
Anemia, Low Iron Stores
Improving Iron Status Through Consumption Of Iron Fortified Cowpea: An Intervention Study
Rationale: Iron deficiency and zinc deficiency, are of public health significance in sub-Saharan Africa. An estimated 50% of children (5-14 years) in developing countries suffer from anaemia, half of which is estimated iron…
- Trial name
- NCT01208363
- Testing
- Cowpea fortified with NaFeEDTA, in form of Toubani.
- Where
- Ghana
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Anemia, Iron Deficiency
Effectiveness of Iron-Fortified Milk on Iron Status and Anemia in Young Children in Mexico
Iron deficiency and anemia in infants and young children impair neurodevelopment. Efficacious interventions for reducing the prevalences of iron deficiency and anemia, under controlled conditions, are available.
- Conditions
- Anemia, Iron Deficiency, Stunting
- Trial name
- NCT00508131
- Testing
- Whole Cows Milk
- Where
- Mexico
- Volunteers
- 798 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Hyperglycemia, Glucose Metabolism Disorders
Effect of Lysine and Phosphorus Fortification on Glycemic Index and Postprandial Glycemia in Double Fortified Bread
The goal of this clinical trial is to investigate the effect of lysine and phosphorous on the glycemic index (GI) of white bread and postprandial glycemia.
- Conditions
- Hyperglycemia, Glucose Metabolism Disorders, Metabolic Disease, Glycemic Index
- Trial name
- LP-DFB-GI-PG (NCT05903625)
- Testing
- Control Group - Standard White Bread, Lysine Group - Lysine-Fortified Bread, Phosphorus Group - Phosphorus-Fortified Bread
- Where
- Pakistan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Stunting, Underweight
Spirulina Supplementation and Infant Growth, Morbidity and Motor Development
Background: In developing countries, micronutrient deficiency in infants is associated with growth faltering, morbidity, and delayed motor development.
- Conditions
- Stunting, Underweight, Pneumonia, Pneumocystis, Cough
- Trial name
- NCT03523182
- Testing
- Spirulina, Control
- Where
- Zambia
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Programme Against Malnutrition