Clinical trials: Fracture, Ankle
Ankle Fractures
Combined Randomised and Observational Study of Surgery for Type B Ankle Fracture Treatment
This study will determine whether operative management confers improved short and long-term outcomes for patients with isolated AO type 44-B1 distal fibula fractures when compared with non-operative management.
- Trial name
- CROSSBAT 5Y (NCT03083028)
- Testing
- Non Operative, Open reduction internal fixation of the ankl
- Volunteers
- 160 people
- Sponsor
- The University of New South Wales
Lateral Ankle Sprain
Lateral Ankle Sprain Study
The purpose of this study is to compare the short term treatment outcome measures of the standard of care air cell stirrup brace to that of a high tide fracture boot in patients with lateral ankle sprains.
- Trial name
- NCT00761865
- Testing
- Air Cast Stirrup Brace & High Tide Fracture Boot
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Rochester
Stress Fracture Foot, Stress Fracture Ankle
Intravenous Bisphosphonate in Stress Fracture Treatment -A Randomised Controlled Double Blinded Multicenter Trial
The effect of an intravenous bisphosphonate (zoledronic acid) on healing and symptoms of stress fractures that do not respond to conservative/conventional treatment within 6 months, will be investigated.
- Trial name
- NCT03576599
- Testing
- Zoledronic Acid Injectable Product
- Where
- Norway
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Plantar Fasciitis, Flatfoot
Foot and Ankle Range of Motion (Stretching) Apparatus
Range of motion at ankle joint and subtalar joint will be assessed before and after utilization of ARM device. The changes in range of motion will be recorded and compared to literature.
- Conditions
- Plantar Fasciitis, Flatfoot, Calcaneus Fractures
- Trial name
- NCT00527748
- Testing
- Non-Measuring Ankle Exerciser
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Missouri-Columbia
Ankle Fractures, Fracture
Outcome of Rehabilitation Following Internally Fixed Ankle Fractures
The purpose of this study is to examine the effect of variations in practice, ranging from early functional rehabilitation to complete immobilsation in post operative patients with ankle fixation following fractures.
- Trial name
- NCT02160197
- Testing
- Aircast XP Walker boot, Plaster Immobilisation
- Where
- United Kingdom
- Volunteers
- 105 people
- Sponsor
- Countess of Chester NHS Foundation Trust
Ankle Fractures, Ankle Fracture - Lateral Malleolus
Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery
This study aims to 1) characterize skeletal muscle pH during/after tourniquet use and 2) investigate any relationship between intraoperative tourniquet use and postoperative functional measures and patient-reported outcomes.
- Conditions
- Ankle Fractures, Ankle Fracture - Lateral Malleolus, Ankle Fracture, Bimalleolar, Ankle Fracture, Trimalleolar
- Trial name
- NCT05445960
- Testing
- Tourniquet
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Oregon Health and Science University
Ankle Fractures, Joint Stiffness
Virtual Reality-Integrated Rehabilitation Versus Conventional Balance Therapy Following Ankle Fracture
This study compares virtual reality-based balance training with conventional balance therapy in adults recovering from an ankle fracture after a period of immobilization.
- Conditions
- Ankle Fractures, Joint Stiffness, Postural Balance, Proprioception, Postural Balance
- Trial name
- NCT07906002
- Testing
- Virtual Reality Balance System (VR-Training), Standard Physical Therapy (Conventional Exercise)
- Where
- 2 sites in Pakistan
- Volunteers
- 22 people
- Sponsor
- Dr Aneeqa Sultan
Fracture Dislocation of Ankle Joint, Fracture Leg
Single Shot Exparel vs Catheters in Lower Extremity Trauma
This study will compare the use of single-shot Exparel, a long-acting local anesthestic, with the use of catheters that deliver a continuous flow of the short-acting local anesthetic ropivacaine.
- Conditions
- Fracture Dislocation of Ankle Joint, Fracture Leg, Fracture Femur, Fracture Lower Leg
- Trial name
- NCT07221019
- Testing
- Bupivacaine, Exparel + Bupivacaine
- Where
- United States
- Sponsor
- George Washington University
Ankle Fracture, Calcaneus Fracture
Manual Therapy After Ankle/Hindfoot Fractures
The aim of this randomized controlled trial is to assess if manual therapy improves mobility, gait, and balance more than a control group for patients who have undergone open reduction internal fixation (ORIF) after an…
- Conditions
- Ankle Fracture, Calcaneus Fracture, Talus Fracture, Pilon Fracture
- Trial name
- NCT02609347
- Testing
- Manual Therapy Group, Control Group
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Intermountain Health Care, Inc.
Rotator Cuff Tears, Shoulder Injuries
Randomized Study of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery
Postoperative pain remains undertreated with inadequate analgesic options. Opioids have well-known limitations for both individuals and society; single-injection and continuous peripheral nerve blocks provide intense analgesia…
- Conditions
- Rotator Cuff Tears, Shoulder Injuries, Hallux Valgus, Ankle Arthropathy
- Trial name
- NCT07052721
- Testing
- Experimental Treatment
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of California, San Diego
Foot Ankle Injuries, Anticoagulants and Bleeding Disorders
A Prospective Study in Chinese Patients With Lower Extremity Ankle Fracture of Oral Anticoagulants to Prevent Venous Thromboembolism (VTE)
Deep vein Thrombosis (Deep Venous Thrombosis, DVT) and Pulmonary Embolism, Pulmonary Embolism, PE) both collectively known as Venous thromboembolism (VTE) (Venous Thrombus Embolism, VTE), is a common clinical disease, and…
- Conditions
- Foot Ankle Injuries, Anticoagulants and Bleeding Disorders, Venous Thromboembolism
- Trial name
- NCT04128254
- Testing
- Apixaban Oral Tablet
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Immobilization, Muscle Disuse Atrophy
Neuromuscular Electrical Stimulation During Immobilization Due to Ankle Fractures
Rationale: Situations such as fractures of the lower extremity can necessitate a prolonged period of immobilization in otherwise healthy individuals.
- Trial name
- ANKL-ES (NCT02469506)
- Testing
- Neuromuscular Electrical Stimulation (NMES)
- Where
- Netherlands
- Volunteers
- 1 people
- Sponsor
- Maastricht University Medical Center
Equinus Contracture
The Effect of Botulinum Toxin A Injections on Ankle Dorsiflexion Following Internal Fixation of Tibial Pilon Fractures
The purpose of this study is to determine if botulinum toxin type A (Botox) injections, at the time of surgery for pilon fractures, will improve ankle range-of-motion and functionality.
- Trial name
- Botox (NCT02051933)
- Testing
- Botulinum toxin type A, sodium chloride
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Tibial Fracture
Transitional Ankle Fracture Management Using a New Joystick Technique
To investigate the feasibility and short-term clinical efficacy of the arthrography-assisted joystick technique for the treatment of adolescent transitional ankle fracture.
- Trial name
- Transitional (NCT05012449)
- Testing
- Arthrography-assisted joystick technology.
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Fuzhou No 2 Hospital
Bimalleolar Ankle Fracture
Fibula Plating vs Intramedullary K-Wire in Bimalleolar Ankle Fractures
This study was conducted to compare the functional outcomes of two commonly used fixation techniques for bimalleolar ankle fractures: fibula plating and intramedullary K-wire fixation with medial malleolar screw.
- Trial name
- FP-KW (NCT07511478)
- Testing
- Fibula Plating Intervention Arm
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Shaikh Zayed Hospital, Lahore
Ankle Fractures
Randomized Controlled Trial for Ankle Fracture Pain Control
This project is a multicenter, three armed, prospective randomized control trial studying the effectiveness of a long-acting local anesthetic "cocktail" in patients undergoing operative fixation of ankle fractures.
- Trial name
- NCT03696199
- Testing
- Long-Acting Local Anesthesia, Regional Anesthesia
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Lahey Clinic
Pain, Postoperative, Pain, Acute Postoperative
Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery
Liposomal Bupivacaine (Exparel) has been recently studied as the active agent utilized in various nerve block. Due to its liposomal form allowing for extended delivery, Exparel has been used in various peri-operative nerve blocks…
- Conditions
- Pain, Postoperative, Pain, Acute Postoperative, Ankle Fractures, Ankle Injuries and Disorders
- Trial name
- NCT05494645
- Testing
- Exparel, Peripheral Nerve Block
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- St. Luke's Hospital, Pennsylvania
Ankle Fractures, Pilon Fracture
Simplified Post Op Rehabilitation for Ankle and Pilon Fractures
The aim of this study is to compare standard post operative rehabilitation with a simplified wooden block stretching protocol that will yield similar results.
- Trial name
- NCT05280639
- Testing
- Wooden block, Formal physical therapy or Home Exercise Program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Virginia
Distal Fibular Fracture, Bimalleolar Fracture
Comparison of Biodegradable & Metal Plates for Fixing Ankle Fracture
A randomised, prospective clinical investigation to compare post-operative fracture healing and complication rate after the fixation of ankle fractures using the Inion OTPS FreedomPlateTM Biodegradable Fixation System versus…
- Conditions
- Distal Fibular Fracture, Bimalleolar Fracture, Trimalleolar Fracture
- Trial name
- NCT00864877
- Testing
- biodegradable fixation system (Inion OTPS FreedomPlateTM)
- Where
- United Kingdom
- Sponsor
- Inion Oy
Blister, Abrasion
Assessing Foot Injuries in Infantry Recruits Wearing Different Boots
One hundred infantry recruits will be randomly assigned to two groups. Injuries will be monitored.
- Conditions
- Blister, Abrasion, Stress Fracture, Ankle Sprain
- Trial name
- NCT02810002
- Testing
- Experimental infantry boot - DEFINITE-REGULATOR, Control infantry boot
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force