Clinical trials: Fractures, Compression
Vertebral Compression Fracture, Facet Joint Pain
Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures
The purpose of this study is to test the efficacy of radiofrequency ablation of the medial branch nerves (RFA-MBN) in relieving pain and improving physical function in patients with subacute and chronic vertebral compression…
- Trial name
- NCT03651804
- Testing
- Radiofrequency ablation of the medial branch nerves, Non-steroidal anti-inflammatory drugs, Bisphosphonates
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Postoperative Pain, Carpal Tunnel Release
Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries
The purpose of this study is to determine the efficacy of intra-operative administration of IV tylenol and/or IV toradol in minimizing post-operative pain for carpal tunnel patients and distal radius fracture patients.
- Conditions
- Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
- Trial name
- NCT02313675
- Testing
- Acetaminophen, Ketorolac Tromethamine, Saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- John Fowler
Transverse Fracture of Shaft of Tibia
Comparison of Interlock Nailing Versus Dynamic Compression Plating in Transverse Fractures of Tibia
Study aims to compare two treatment modalities for treatment of transverse fractures of tibia. One is Intramedullary interlocking nail and the other is dynamic compression plate.
- Trial name
- NCT04958564
- Testing
- DCP
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- District Headquarters Teaching Hospital Sahiwal
Osteoporosis, Fractures, Compression
Dynamic Magnetic Resonance (MR) Study in Evaluating the Vertebral Bone Marrow Perfusion and Its Related Research
The etiology and pathogenesis of osteoporosis has been extensively discussed. The relationship between bone blood circulation and the formation of bony trabeculae has been less understood.
- Trial name
- NCT00172224
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Posture, Vertebral Compression Fracture
The Spine Kinematics and Center of Pressure Excursion During Functional Task Vertebral Compression Fractures Subjects
This study aimed to assess the sensory and kinematic components of the limits of stability (LOS) test in patients with vertebral compression fracture (VCF) .
- Trial name
- NCT04135755
- Testing
- no drug intervention
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Anterior Mandibular Fracture
Evaluation of Condylar Position After Anterior Mandibular Fracture Fixation Using Plates Versus Headless Compression Screws
This study compares two methods for fixing fractures of the front part of the lower jaw: Conventional plates and screws Headless compression screws Patients are randomly assigned to one of the two treatment groups.
- Trial name
- fracture (NCT07826403)
- Testing
- headless compression screw, conventional plates
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sternal Fracture, Sternal Wound Infection
Sternal Wound Infection in Patients Undergone Sternal Fixation Using Locking Compression Plates
Sternal Wound Infection (SWI) in open heart surgery is one of the most annoying and avoidable complications that one encounters during work.
- Conditions
- Sternal Fracture, Sternal Wound Infection, Surgical Site Infection
- Trial name
- NCT05040399
- Testing
- Locking Compression Plates, Sternal Wires
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Assiut University
Denosumab vs Zoledronate
Denosumab vs Zoledronic Acid and Osteoporotic Compression Fracture
Bone mineral density and function at 1 year after screw fixation with denosumab vs zoledronic acid for osteoporotic vertebral compression fractures: a parallel double-blind randomized controlled clinical trial
- Trial name
- NCT05106517
- Testing
- Denosumab, Zoledronic acid
- Where
- China
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Shenzhen People's Hospital
Spinal Fractures
A Safety and Efficacy Study for Treatment of Painful Vertebral Compression Fractures Caused by Osteoporosis
Doctors are studying an investigational treatment to be used during the vertebroplasty procedure when treating vertebral compression fractures (spine fractures) that may help to reduce pain and restore mobility.
- Trial name
- NCT00290862
- Testing
- Percutaneous Vertebral Augmentation of compression fractures
- Where
- 18 sites in United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Orthovita d/b/a Stryker
Tibial Shaft Fracture
Study of Tibial Shaft Fracture Fixation: Intramedullary Nailing Comparing With Dynamic Compression Plate
The purpose of this study is to determine which surgical approach is better for treatment of tibial shaft fracture
- Trial name
- NCT01190709
- Testing
- Dynamic Compression Plate, Unreamed intramedullary nailing
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Vertebral Compression Fractures
OsseoFix™ Spinal Fracture Reduction System in Treating Spinal Compression Fracture
The OsseoFix Spinal Fracture Reduction System facilitates the treatment of spinal fractures by providing internal fixation and stabilization using a titanium implant in conjunction with OsseoFix+™ polymethylmethacrylate (PMMA)…
- Trial name
- OsseoFix (NCT00961714)
- Testing
- OsseoFix Spinal Fracture Reduction System
- Where
- 11 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Alphatec Spine, Inc.
Osteoporosis, Postmenopausal
The Prevalence of Osteoporotic Vertebral Compression Fractures (OVCF) in Korean Post Menopausal Women
This is an observational study to investigate the prevalence of osteoporotic fractures in post menopausal patients. Post menopausal patients who visit OS(orthopedic surgery) including GHs(general hospitals) and clinics will be…
- Trial name
- TOP (NCT01381588)
- Testing
- Fracture evaluation
- Where
- South Korea
- Volunteers
- 1,136 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Back Pain Lower Back Chronic
The Impact of an Instructional Web-based Healthcare App for Relieving Back Pain From Spinal Compression Fractures
With the expected rise of patients with osteoporosis-induced fractures, it has become increasingly urgent to design and use specialized health education materials aimed at easing pain and improving bodily functions
- Trial name
- NCT05386212
- Testing
- web app healthcare instructions for relieving back pain
- Where
- 3 sites in Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Vertebral Compression Fracture, Kyphoplasty
Anesthesia for Percutaneous Kyphoplasty
The aim of this study was to compare ESP with conventional local infiltration anesthesia (CLIA) and extrapedicular infiltration anesthesia (EPIA) with respect to analgesic efficacy in patients underwent elective PKP for VCF.
- Trial name
- Kyphoplasty (NCT07091513)
- Testing
- group ESP
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Compression Fracture
QOCA®-Image Medical Platform - Smart VCF Risk Management System
This project aims to develop and validate an automatic detection and classification system for vertebral compression fractures on computer tomography (CT) images using an artificial intelligence (AI) system (named Smart Bone) by…
- Trial name
- NCT04384211
- Testing
- Computer Assisted Detection Software For Vertebral Fractures
- Where
- Taiwan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
OVCF Database, Cohort Study
Osteoporotic Vertebral Compression Fracture Cohort Study
The study aims to construct an early warning model for Osteoporotic Vertebral Compression Fracture (OVCF) by integrating TCM syndrome patterns with modern risk factors.
- Trial name
- NCT07321795
- Where
- 4 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wangjing Hospital, China Academy of Chinese Medical Sciences
Surgical Complication, Paresthesia
Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw.
- Conditions
- Surgical Complication, Paresthesia, Fracture, Nerve Injury
- Trial name
- NCT05205616
- Testing
- Sonopet ultrasonic saw, Reciprocating saw
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Osteoporotic Vertebral Compression Fracture
Denosumab and Osteoporotic Vertebral Compression Fracture
This study aimed to investigate the effect of denosumab on bone mineral density(BMD), bone turnover markers(BTMs), functional status, secondary fracture rate, and adverse effects in osteoporotic vertebral compression fracture…
- Trial name
- NCT05058443
- Testing
- Denosumab 60 mg/ml [Prolia]
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shenzhen People's Hospital
Denosumab Allergy
Denosumab and Screw Fixation for Osteoporotic Compression Fracture
Evaluation of bone mineral density and function at 1 year after screw internal fixation of osteoporotic vertebral compression fractures with desuzumab: a parallel double-blind randomized controlled clinical trial
- Trial name
- NCT05065164
- Testing
- Denosumab Only Product
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shenzhen People's Hospital