Clinical trials: Fractures in the Elderly
Hip Fractures, Anemia
The Effect of Preoperative Ferric Carboxymaltose Administration on Mortality in Geriatric Hip Fractures
Hip fractures (HF) are the most common and serious pathology affecting the hip and are associated with a high mortality risk in elderly patients.
- Conditions
- Hip Fractures, Anemia, Complication,Postoperative
- Trial name
- NCT06080893
- Testing
- Ferric carboxymaltose
- Where
- Turkey (Türkiye)
- Volunteers
- 209 people
- Sponsor
- Istanbul University
Accidental Falls, Fractures
Falls With Fracture : Role of Cognitive Disorders and Comparison With Bone Fragility
The purpose of this study is to determine whether cognitive disorders are a risk factor for a fracture after a fall independently of a bone fragility.
- Trial name
- CFC (NCT02292316)
- Testing
- gait and cognitive assessments, blood sample, osteodensitometry
- Where
- 2 sites in France
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Colles' Fracture, Distal Radius Fracture
Conservative Treatment of Distal Radius Fracture in Elderly in Randomized Controlled Trial
There is no consensus about the best conservative treatment for patients with dorsally displaced distal radius fractures. The previous studies that have examined the most valid method for cast immobilization have lacked uniform…
- Trial name
- NCT02894983
- Testing
- Flexion-ulnar cast, Functional cast
- Where
- 3 sites in Finland
- Volunteers
- 114 people
- Sponsor
- Tampere University Hospital
Postoperative Delirium
The Preventive Effect of Different Doses of Intranasal Insulin on Postoperative Delirium
Postoperative delirium is one of the common complications in the older aldults after surgery, which can lead to longer hospita stay，memory loss and reduced quality of life. There is currently no specific treatment.
- Trial name
- NCT06443957
- Testing
- Intranasal normal saline, Intranasal insulin-20U, Intranasal insulin-40U
- Where
- China
- Volunteers
- 129 people
- Sponsor
- The First Hospital of Jilin University
Osteoporotic Fractures, Osteoporosis
Stop At One Stockholm (SAOS)- Secondary Fracture Prevention Through Active Patient Identification and Staff Education.
This is a study on the effects of education on secondary fracture prevention in primary health care centers (PHCC) and referral from hospitals to these PHCC of patients with recent fragility fractures.
- Conditions
- Osteoporotic Fractures, Osteoporosis, Osteoporosis Risk
- Trial name
- SAOS (NCT04565743)
- Testing
- Support on dentification and treatment of patients with high risk of osteoporotic fractures
- Where
- Sweden
- Volunteers
- 38 people
- Sponsor
- Helena Salminen
Distal Radius Fracture, Colles Fracture
Wrist Injury Strengthening Exercise (WISE) Versus Usual Care Advice for Improving Pain and Function
The goal of this clinical trial is to find out whether a therapist-guided exercise program helps people aged 50 and older recover better, in terms of pain and function, after a wrist fracture, compared to the usual care advice…
- Conditions
- Distal Radius Fracture, Colles Fracture, Wrist Fracture, Wrist Fractures
- Trial name
- WISE-DK (NCT07538323)
- Testing
- Supervised Exercise, Usual Care
- Where
- Denmark
- Volunteers
- 588 people
- Sponsor
- University of Aarhus
Accidental Falls, Fractures
Clinical Evaluation of a Wireless Monitoring Device to Reduce Falls in the Elderly and Others at High Risk of Falling
Falls are a public health problem of significant social and economic significance. No primary intervention devices have been shown to be effective in reducing falls and associated injuries.
- Conditions
- Accidental Falls, Fractures, Injuries
- Trial name
- NCT00249743
- Testing
- FallSaver (formerly called NOCwatch)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NOCwatch International
Proximal Humeral Fractures
Effect of Osteosynthesis, Primary Hemi-arthroplasty, and Non-surgical Management for Fractures of the Proximal Humerus
Displaced four-part fractures are among the most severe injuries of the proximal humerus. The optimal treatment is disputed and published data are inadequate for evidence-based decision making.
- Trial name
- NCT00835562
- Testing
- Non-surgical management, Osteosynthesis, Hemiarthroplasty
- Where
- Denmark
- Volunteers
- 162 people
- Sponsor
- Herlev Hospital
Olecranon Fracture
Scandinavian Olecranon Research in the Elderly
This study is designed to study the difference between operative treatment, either with tension band wiring or plate fixation, and conservative treatment of traumatic, displaced olecranon fractures in elderly population in a…
- Trial name
- NCT04401462
- Testing
- Tension band wiring or plate fixation, Sling or a long-arm plaster
- Where
- 4 sites in Finland, Sweden
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Femoral Neck Fractures
Project JAY HAP Registration Study
This is a prospective, randomized, multicenter clinical study in elderly Chinese subjects to compare the safety and efficacy of the SS Bipolar Head and SL-TWIN Stem with Bipolar Head and SL-PLUS Stem in hemiarthroplasty of the hip
- Trial name
- NCT02347397
- Testing
- SS Bipolar Head + SL-TWIN Stem, Bipolar Head + SL-PLUS Stem
- Where
- 5 sites in China
- Volunteers
- 134 people
- Sponsor
- Smith & Nephew Orthopaedics (Beijing) Limited
Thoracolumbar, Fractures in the Elderly
Monoaxial vs. Polyaxial Percutaneous Hybrid Stabilization
Vertebral body fractures in older adults mostly affect the thoracolumbar junction and are challenging to treat due to osteoporosis and other comorbidities.
- Trial name
- NCT07408726
- Testing
- Monoaxial instrumentation - the M.U.S.T. Monoaxial Pedicle Screw Cannulated (Medacta International SA, Switzerland), Polyaxial instrumentation - the M.U.S.T. LT Pedicle Screw System (Medacta International SA, Switzerland)
- Where
- Austria
- Volunteers
- 44 people
- Sponsor
- Medical University Innsbruck
Femoral Neck Fractures
the Effects of Perioperative Goal Directed and Conventional Fluid Management on the IVC Collapsibility Index
The investigators aimed to compare the effects of targeted fluid management and traditional fluid management on the inferior vena cava collapsibility index in participants who will undergo proximal femoral surgery.
- Trial name
- NCT05154435
- Testing
- mostcare hemodynamic monitor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Femoral Neck Fracture
Influence of the Spatial Distribution of Hollow Screws on the Blood Supply and Prognosis of Femoral Neck Fractures
Femoral neck fracture is a common type of fracture in the elderly. For those without significant displacement (Garden I, II), more hip-preserving treatment strategies are adopted.
- Trial name
- NCT05171140
- Testing
- Triangular Nail Placement of Femoral Neck
- Where
- China
- Volunteers
- 68 people
- Sponsor
- RenJi Hospital
Fragility Fractures of the Pelvis (FFP), Osteoporosis
Robot Assisted Minimally Invasive Treatment Versus Conventional Surgery for FFP3-4 Fragility Fractures of the Pelvis in Elderly Patients
This prospective randomized controlled trial aims to compare the efficacy and safety of robot assisted minimally invasive treatment versus conventional surgery in elderly patients with FFP3-4 fragility fractures of the pelvis.
- Trial name
- NCT07639619
- Testing
- Robot Assisted Minimally Invasive Fixation, Conventional Open Fixation
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Junbo Liang
Cancer Metastatic, Trauma
IlluminOss Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pelvis Fractures
The aim of this project is to assess the effectiveness of the IlluminOss pelvic implants in patients with pelvic metastatic disease presenting with pain, risk of pathologic fracture, non-displaced or minimally displaced…
- Conditions
- Cancer Metastatic, Trauma, Pathologic Fracture
- Trial name
- NCT04842266
- Testing
- IlluminOss pelvic implant for oncologic indication, IlluminOss pelvic implant for geriatric trauma indication
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Cerebrovascular Accident, Hip Fracture
The Relationship Between Pet Therapy and "Well-being" in Geriatric Rehabilitation In-patients
In -patients in a geriatric rehabilitation unit, will participate in structured therapy with guinea-pigs on the assumption that the therapy will reduce anxiety and improve the outcome of their rehabilitation.
- Trial name
- NCT01234844
- Testing
- care of guinea pigs, guinea pigs
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Meir Medical Center
Multiple Rib Fractures, Isolated Blunt Thoracic Trauma
GNRI and PNI for Predicting Short-Term Outcomes in Older Adults With Multiple Rib Fractures
This prospective observational cohort study will evaluate whether the Geriatric Nutritional Risk Index (GNRI) and Prognostic Nutritional Index (PNI) can predict short-term clinical outcomes in adults aged 65 years or older with…
- Trial name
- NCT07823712
- Where
- Turkey (Türkiye)
- Volunteers
- 294 people
- Sponsor
- Ankara Etlik City Hospital
Delirium, Bone Fractures
The DETEcT Study - Delirium in Elderly paTiEnts Admitted to Trauma
Primary objectives are to define incidence and prevalence of Delirium in an elderly population admitted to the Department of Orthopedics and Traumatology and, in the postoperative phase, in the high Dependency Unit as well as to…
- Conditions
- Delirium, Bone Fractures, Multiple Trauma
- Trial name
- DETEcT (NCT02086981)
- Where
- Italy
- Volunteers
- 672 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Pelvic Pain
Treatment of Pelvic Ring Fractures in the Elderly
Pelvic ring fractures in the elderly are associated with high morbidity during standard conservative treatment due to immobility. Furthermore the risk of long term dependence even after the fracture has united is high.
- Trial name
- NCT02590783
- Testing
- experimental intervention surgery, control intervention
- Where
- Switzerland
- Volunteers
- 88 people
- Sponsor
- University Hospital, Basel, Switzerland
Fracture
Surgical Treatment of Low Energy Pelvic Fractures in the Elderly
Since May 2010 the Department of Trauma, Basel University Hospital has performed surgical stabilisation of the posterior pelvic ring on 55 patients.
- Trial name
- PelvicRetro (NCT02591043)
- Testing
- Outcome after surgery
- Where
- Switzerland
- Volunteers
- 79 people
- Sponsor
- University Hospital, Basel, Switzerland