Clinical trials: Frail
Cancer, Frail
Resilience Enhancement Using Electronic Frailty Index-Directed Care Pathway
The study purpose is to gain a better understanding of the needs of adults aged 65 and older while they are receiving chemotherapy by measuring their resilience and tailor care plans based on their individual needs.
- Conditions
- Cancer, Frail, Chemotherapy
- Trial name
- NCT07175376
- Testing
- Supportive Care
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Wake Forest University Health Sciences
Older Adults (65 Years and Older), Outpatient Treatment
Feasibility of Virtual Reality-assisted Ergometer Cycling in Addition to Regular Rehabilitation During Municipality-based Inpatient Rehabilitation Care
VR-C-REHAB is a single-group pilot and feasibility study examining the practicality of implementing virtual-reality-assisted ergometer cycling as an adjunct to usual municipal inpatient rehabilitation for older adults (≥65…
- Conditions
- Older Adults (65 Years and Older), Outpatient Treatment, Rehabilitation Frail Elderly Subjects
- Trial name
- VR-C-REHAB (NCT07459439)
- Testing
- VR cycling
- Where
- 2 sites in Denmark
- Volunteers
- 12 people
- Sponsor
- Horsholm Municipality
Frailty Syndrome, Prefrail Elderly
Comparıson of the Effıcacy of Conventıonal Exercıse and Pılates ın Pre-fraıl and Fraıl Older Adults
Brief Summary This clinical study aims to compare the effects of a conventional exercise program and a Pilates exercise program in prefrail and frail older adults.
- Conditions
- Frailty Syndrome, Prefrail Elderly, Frail Elderly, Geriatric
- Trial name
- NCT07458048
- Testing
- PILATES EXERCISES GROUP, CONVENTIONAL EXERCISES GROUP
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Elderly, Frail
Implementation of a Personalised Health Plan (PHP) on Patient Quality of Life Score at 2-year Follow-up
"Healthy ageing" is not limited to the absence of disease, but implies the "development and maintenance of the functional skills that enable the elderly to enjoy a state of well-being": (for example : the ability to walk, go out…
- Trial name
- FRAPA (NCT06560723)
- Testing
- Quality of life test
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Rouen
Frail Elderly, Elderly
Fine-tuned Physical Training to Improve Quality of Life in Older Individuals
The overall aim of this project, which is based upon the interdisciplinary expertise of four research groups within the University of Rome Foro Italico, in the macro-areas of psychology, bioengineering, physiology, and internal…
- Conditions
- Frail Elderly, Elderly, Aging, Aging Frailty
- Trial name
- NCT07546734
- Testing
- Resistance Training (RT), Resistance training + CORE (RT+CORE), CMDT training
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- University of Rome Foro Italico
Cognitive Dysfunction, Mobility Limitation
Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults
Declines in cognitive function and walking function are highly intertwined in older adults. A therapeutic approach that combines complex (cognitively engaging) aerobic walking exercise with non-invasive electrical brain…
- Conditions
- Cognitive Dysfunction, Mobility Limitation, Frail Elderly
- Trial name
- NCT05830942
- Testing
- Walking Exercise, Prefrontal Active tDCS
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Florida
Pre-Frail Older Adults
Pharyngeal Exercise (Plus Protein)
The swallowing muscles are prone to decreased strength and function as part of the natural aging process which can lead to difficulty swallowing, malnutrition, and frailty.
- Trial name
- PE(PP) (NCT05963113)
- Testing
- Pharyngeal Swallowing Exercises, Protein Supplementation, MRI
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Type2diabetes, Frail Elderly Syndrome
The Impact of Geriatric Assessment on the Treatment Plan of Elderly Patients With T2DM
Introduction: With the aging of the world population and the increasing incidence of type 2 diabetes mellitus (T2DM) with age, the number of elderly individuals living with diabetes has been considerably rising.
- Conditions
- Type2diabetes, Frail Elderly Syndrome, Frailty, Geriatric Assessment
- Trial name
- NCT06469437
- Testing
- Providing the physicians with a proposed glycated hemoglobin target
- Where
- Brazil
- Volunteers
- 220 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Frail Elderly Syndrome
Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Adults
This is a pilot study to test the efficacy of the anti-inflammatory drug (Fisetin) in reducing inflammatory factors in blood in elderly adults and to test the efficacy of the drug (Fisetin) in reducing frailty and markers of…
- Trial name
- AFFIRM-LITE (NCT03675724)
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Pre-frail, Pre-Frail Older Adults
The Impact of Whey Protein on Frailty in Older Adults Classified as Pre-frail
This pilot study aims to determine the impact of whey protein supplementation on brain antioxidant levels and to assess the effects of whey protein supplementation on physical function, body composition, and cognition in…
- Conditions
- Pre-frail, Pre-Frail Older Adults, Cognition, Physical Function
- Trial name
- NCT07167277
- Testing
- Whey Protein
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center
Frail Elderly Patients, Geriatric Syndromes
Improving Care for Frail Older Adults Using a Digital Needs Assessment Tool
The goal of this trial is to evaluate whether a digital needs-assessment tool can improve care planning and outcomes for frail older adults (aged 60 years and above) hospitalized in Singapore.
- Conditions
- Frail Elderly Patients, Geriatric Syndromes, Frail Older Adults
- Trial name
- Frailty (NCT07580690)
- Testing
- Core: SST-informed care planning, Additional telephone calls
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- Duke-NUS Graduate Medical School
Frail Elderly Syndrome
Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women
This is a pilot study to evaluate whether targeting inflammation will help reduce markers of insulin resistance inflammation, bone resorption and physical dysfunction in elderly women with gait disturbance.
- Trial name
- AFFIRM (NCT03430037)
- Testing
- Fisetin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Heart Failure, Prefrail Elderly
High-technology TeleRehabilitation for the Treatment of the FRAgile Patient
The aim of this randomized controlled clinical trial is to evaluate the efficacy of an 8-week sensorimotor and cognitive telerehabilitation program in frail and pre-frail older adults with stable chronic heart failure.
- Conditions
- Heart Failure, Prefrail Elderly, Frail Elderly Syndrome
- Trial name
- TeleRiab4Fra (NCT07561021)
- Testing
- Telerehabilitation, Caregiver-Supervised Home Exercise Program
- Volunteers
- 70 people
- Sponsor
- University of Salerno
Frail Elderly Patients, Hypogonadal Males
Effect of Testosterone on Elderly Frail Men With Testosterone Deficiency
The purpose of this study is to increase the functional level of the elderly to thereby reduce fall risk, improve motor skills, and increase psychological well-being, as well as to assess whether the restoration of a normal…
- Conditions
- Frail Elderly Patients, Hypogonadal Males, Testosterone Replacement Therapy, Falls (Accidents) in Old Age
- Trial name
- NCT07512323
- Testing
- Nebido (Testosterone Undecanoate)
- Where
- Denmark
- Volunteers
- 96 people
- Sponsor
- Rune Skovgaard Rasmussen
Frail Elderly
High Intensity Interval Training Versus Moderate Intensity Continuous Training in Frail Elderly
The assessment and systematic integration of physical activity into the care pathway of frail elderly people is essential to prevent loss of independence and improve the quality of life of this population.
- Trial name
- EPAF (NCT07211334)
- Testing
- Exercise Training
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Grenoble
Frail Elderly
Cognitive Function and Prevalence of Amyloid Marker in Frail Older Adults
The current study seeks to examine the prevalence of amyloid pathology, among patients referred to the Toulouse Geriatric Frailty Clinic presenting objective memory impairment.
- Trial name
- COGFRAIL (NCT03129269)
- Testing
- MRI and PET scan
- Where
- France
- Volunteers
- 344 people
- Sponsor
- University Hospital, Toulouse
Frail Elderly
Comparison of the Effects of Different Exercise Protocols in Frail Elderly Individuals
The aim of this research is to investigate and compare the effects of two different exercise programs developed for frail geriatric individuals on fall risk, fear of falling, and physical performance.
- Trial name
- NCT07564076
- Testing
- Vivifrail Exercise Program, Otago Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Frail Elderly Syndrome
Assessing a New Tool to Assess Frailty in Frail Hospitalized Elderly
The major purpose of this study is to establish the use of daily step counts as inexpensive, easy to measure marker for frailty and sarcopenia in an inpatient population of older adults.
- Trial name
- NCT04366388
- Testing
- ActivPAL3 VT (PAL Technologies Ltd).
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of British Columbia
Aging, Frail Elderly
EFFECT OF ANIMATION-BASED DIGITAL EDUCATION ON RISK KNOWLEDGE AND FRAILTY IN OLDER ADULTS
With the global aging trend, the management of geriatric risks faced by older adults and the effectiveness of health education for this population are gaining increasing importance.
- Conditions
- Aging, Frail Elderly, Geriatric Syndromes
- Trial name
- NCT07547358
- Testing
- Branching Scenario Animation Education
- Volunteers
- 66 people
- Sponsor
- Saglik Bilimleri Universitesi
Frail Patient, Cardiac Surgical Procedures (Postoperative Population)
Individualized Nursing Care and Frailty Outcomes in Cardiac Surgery
This study is a randomized controlled trial aiming to compare targeted individualized nursing care with standard care in frail elderly patients undergoing cardiac surgery.
- Conditions
- Frail Patient, Cardiac Surgical Procedures (Postoperative Population), Patient-centered Care, Clinical Outcomes
- Trial name
- NCT07471945
- Testing
- Experimental
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- SELDA MERT