Clinical trials: Frailty
Physical Inactivity, Frailty
The 'Outdoor Rehab-Fit' App-based Physical Activity Education Intervention for Frail Older Adults in Hong Kong
In recent years, research teams around the world have developed interventions to educate older adults to use outdoor exercise facilities (OEFs) to improve health outcomes like strength, balance, mobility, PA level, and weight.
- Trial name
- NCT06326710
- Testing
- mHealth, Health Talk
- Where
- Hong Kong
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Locomotor Activity, Functionally-Impaired Elderly
Reliability and Validity of the Elderly Mobility Scale, French Version
This study evaluates the reliability of the French version of the "elderly mobility scale" and its correlation with the "frailty elderly scale "
- Conditions
- Locomotor Activity, Functionally-Impaired Elderly, Frail Elderly
- Trial name
- NCT03008135
- Testing
- Elderly Mobility Scale, Frailty scale
- Where
- 3 sites in France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pole Santé Plouasne Saint Pern Becherel
Sarcopenia, Aging
Effects of Polyphenol Supplementation and Exercise on Physical Performance in Older Adults
After approximately age 40 years, individuals experience a natural loss of muscle mass, strength, and physical function that is linked to higher risks of falls, disability, loss of independence, and mortality.
- Conditions
- Sarcopenia, Aging, Frailty
- Trial name
- NCT07441343
- Testing
- Polyphenol Rich-Extract, Resistance Band-Based & Aerobic Stationary Cycling Exercise
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. Chris McGlory, PhD
Frailty, Length of Stay
Evaluation of Prioritized Assessment for Older Patients Living With Frailty Presenting to the Emergency Department
The older population is getting older and growing in size worldwide. This requires healthcare to adapt to meet the complex medical and nursing needs of the older patient group.
- Conditions
- Frailty, Length of Stay, Emergency Department Visit, Older Patients
- Trial name
- NCT06869148
- Testing
- Prioritized assessment for older patients living with frailty
- Where
- Sweden
- Volunteers
- 1,217 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Frailty, Sarcopenia
Development of Frailty Prevention Clinic in Geriatric Comprehensive Clinic RSCM:
There is an increasing number of elderly population, not only in Indonesia, but also in the world. With increasing of age, there is also an increasing number of elderly with sarcopenia and frailty.
- Conditions
- Frailty, Sarcopenia, Resistance Training
- Trial name
- NCT05511311
- Testing
- Resistance Training, Standard Therapy
- Where
- Indonesia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Stability, Old Age; Debility
The Feasibility of a Dynamic Exercise Intervention. Psychosocial Effects and Process Evaluation of the Experimental Design.
Current balance and stability interventions have been shown to improve balance through targeting balance impairments and retraining effects.
- Conditions
- Stability, Old Age; Debility, Balance; Distorted
- Trial name
- NCT04932408
- Testing
- Evaluation of the feasibility, psychosocial effects, influence and perception of exercise selection an experimental design of exercises performed at the hip and chest region.
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Derby
Age-related Muscle Decline
CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy
This Phase 1/2a, open-label, non-randomized study is designed to evaluate the safety and tolerability of intramuscular AAV9-Follistatin gene therapy administered either as monotherapy or in combination with a VEGF-encoding…
- Trial name
- CALM-AF-AI (NCT07443826)
- Testing
- AAV9-Follistatin gene therapy, VEGF Plasmid
- Where
- Honduras
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Unlimited Biotechnology LLC
Dysphagia, Frailty
Frailty and Dysphagia in Older Adults
The purpose of this research study is to figure out if there are physical factors such as cognition level, nutrition status, walking speed, and handgrip strength that are associated with the development of swallowing problems.
- Trial name
- NCT04975815
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Art, Wellness, Psychological
The Singapore Art-Health Study
The goal of the Singapore Art-Health RCT is to examine the effect of a standardized 12-week museum -based participatory art program on health condition, well-being, and quality of life in older community dweller, one that adheres…
- Conditions
- Art, Wellness, Psychological, Frailty, Quality of Life
- Trial name
- NCT05945589
- Testing
- Singapore A-Health Intervention
- Where
- Singapore
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Aging Disorder, Age Problem
Health Status and Its Socio-economic Covariates of the Older Population in Poland - the Nationwide PolSenior2 Survey.
The PolSenior2 survey is aimed to characterise health status of old and very-old adults in Poland.
- Conditions
- Aging Disorder, Age Problem, Healthy Aging, Immunity Disorders
- Trial name
- PolSenior2 (NCT04026815)
- Testing
- medical history, blood and urine tests
- Where
- Poland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Oral Manifestations
The Oral Biomechanical Functions of Hong Kong Healthy Adults
Hong Kong and Japan are similar in terms of facing the super-ageing society. Maintaining oral function in elderly is particularly important because it affects social, physical and mental health to the people and to the society.
- Trial name
- NCT05549648
- Testing
- Home oral excrise
- Where
- Hong Kong
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Frailty
Application of Frailty Prevention Care Management Program of Community Elderly Adults
This study first explored the relationship between basic demographic variables, frailty and health function of community-based adults and elderly.
- Trial name
- NCT05883423
- Testing
- FPCMP-Old Age
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Frail Elderly
Prevalence of Malnutrition and Frailty Among the Urban Community Elderly in Bandung
The goal of this observational study is to learn prevalence of malnutrition and frailty in elderly in Community in Bandung. The main question it aims to answer: what is the prevalence of malnutrition and frailty in elderly in…
- Trial name
- NCT06701045
- Where
- Indonesia
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Benign Paroxysmal Positional Vertigo
Benign Paroxysmal Positional Vertigo in Older Adults
Despite the growing research on Benign Paroxysmal Positioning Vertigo (BPPV), the impact and treatment efficacy on balance, physical activity (and consequently) frailty in elderly is lacking.
- Trial name
- NCT05013684
- Testing
- Particle Repositioning Maneuver
- Where
- Belgium
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Mild Cognitive Impairment, Old Age; Debility
Dual Task Perturbation Training for OAwMCI
Studies have determined that compared to cognitively intact older adults (CIOA), older adults with mild cognitive impairment (OAwMCI) exhibit more pronounced balance and gait impairments which lead to an increased risk of falls…
- Trial name
- NCT04938349
- Testing
- Dual task perturbation training
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Frailty, Muscle Weakness
Effectiveness of Protein Supplementation on Frailty Improvement, Muscle Strength and Physical Performance Among Pre-Frail Elderly People
The goal of this randomized clinical trial is to study the effectiveness of protein supplements in frailty improvement, muscle strength, physical performance, energy intake and body composition of pre-frail elderly people.
- Conditions
- Frailty, Muscle Weakness, Physical Dependence, Weight Loss
- Trial name
- NCT05648617
- Testing
- SUSTINEX Hydrolyzed Whey Protein
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Ageing
Effect of Strength Training and Protein Supplementation on Muscles in the Very-old
Three months intervention study, investigating the effect of nutrient supplementation (including 20g of milk protein) twice daily with or without additional heavy resistance exercise three times weekly on muscle size, structure…
- Trial name
- 83+ (NCT01997320)
- Testing
- Heavy resistance exercise and nutrition, Nutrition supplement
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Functional Status, Cognitive Impairment
Effects of a Daily Cognition Training in Older Adults Without Cognitive Impairment
To evaluate the effectiveness of a daily cognition training programme versus a traditional cognitive stimulation programme in cognitively unimpaired older adults on cognitive function, emotional state, frailty and functionality.
- Conditions
- Functional Status, Cognitive Impairment, Occupational Therapy
- Trial name
- NCT05688163
- Testing
- programme based on everyday cognition, traditional cognitive stimulation
- Where
- Spain
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Fall, Old Age; Debility
The Turkish Version of the Survey of Activities and Fear of Falling in the Elderly
The Survey of Activities and Fear of Falling in the Elderly (SAFE) was originally developed in English to determine the level of fear of falling and its interactions with activities of daily living.
- Conditions
- Fall, Old Age; Debility, Fear, Activity, Motor
- Trial name
- NCT04139109
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Frailty Syndrome, Geriatric Health
Longitudinal Assessment of Lung Function and Respiratory Muscle Strength Following Training of the Inspiratory Muscles in Frail Older Adults (IMT-3)
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on lung function and respiratory muscle strength in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Geriatric Health, Respiratory Muscle Weakness, Age-Related Frailty
- Trial name
- NCT07556445
- Testing
- Inspiratory Muscle Training
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria