Clinical trials: Frailty, completed
Chronic Pain, Frailty
Assessing the Relationship Between Chronic Pain and Frailty in Older Adults
Pain is an unpleasant emotional sensation related to one's past experiences, originating from a certain part of the body, due to tissue damage or not. Pain is the most commonly reported symptom in the elderly.
- Trial name
- NCT06672003
- Testing
- 4 meter walking speed and hand grip strength
- Where
- Turkey (Türkiye)
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Frailty, Well-Being, Psychological
Home-based Psychoeducation for Older Adults With Frailty: A Feasibility Trial
This study aims to test the feasibility and acceptability of home-based psychoeducation in older adults with frailty in the community. The main questions it aims to answer are 1.
- Trial name
- NCT06415617
- Testing
- Psychoeducation, Attention control
- Where
- Hong Kong
- Volunteers
- 24 people
- Sponsor
- TAO An
Gastric (Stomach) Cancer, Frailty
Skeletal Muscle Mass Used to Assess Frailty in Older Gastric Cancer Patients
The primary aim of this study was to quantify the diagnosis of pre-surgical skeletal muscle mass in elderly gastric cancer patients and to analyse its correlation with frailty.
- Conditions
- Gastric (Stomach) Cancer, Frailty, Sarcopenia, Malnutrition Elderly
- Trial name
- NCT06763068
- Testing
- Skeletal muscle mass and frailty
- Where
- China
- Volunteers
- 575 people
- Sponsor
- Nanjing Medical University
Frail Elderly Syndrome
No Association Between Vitamin C and E Supplementation, Frailty, and Grip Strength Over Five Years: The CoLaus Study
To assess the cross-sectional and 5-year prospective association between self-reported vitamin C+E dietary supplementation and markers of grip strength and frailty in community-dwelling Swiss adults.
- Trial name
- CoLaus (NCT03258970)
- Testing
- Observational cohort study
- Where
- Switzerland
- Volunteers
- 2,711 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Geriatrics
Efficacy of Samsung GEMS-H Device Training in Older Adults
The purpose of this study is to evaluate the feasibility of using Samsung robotic hip assist-based mobility intervention for older adults with frailty.
- Trial name
- NCT05197127
- Testing
- exoskeleton-based gait training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Frail Elderly Syndrome
GrandMove Project to Promote Elders' Robustness Against Frailty
This is a single-blind, cluster randomized, cross-over trial to investigate the effectiveness of (1) a 6-month aerobic exercise program, (2) a 6-month resistance exercise program, versus (3) a 6-month psychoeducation program on…
- Trial name
- GrandMove (NCT05397288)
- Testing
- Resistance exercise (R), Aerobic exercise (A), Healthy lifestyle education (E)
- Where
- Hong Kong
- Volunteers
- 390 people
- Sponsor
- The University of Hong Kong
Symptomatic Aortic Stenosis
Geriatric Evaluation to Predict Mortality and Functional Recovery After Trans Aortic Valve Implantation
Transcutaneous trans-aortic valve replacement (TAVR) is now a common procedure to treat symptomatic aortic stenosis. Although as effective and safe as surgical aortic valve replacement, it is still restricted to high surgical…
- Trial name
- EVA-G-TAVI (NCT02424370)
- Testing
- TAVR
- Where
- France
- Volunteers
- 515 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Acute, Malnutrition
The Effect of Nutrition Counseling on Nutritional Status in Stroke Patients
The purpose of this study is to investigate the effect of intensive nutrition counseling on nutritional status and functional recovery in stroke patients over the age of 65, compared to standard nutrition counseling.
- Conditions
- Stroke, Acute, Malnutrition, Old Age; Debility
- Trial name
- NCT06208969
- Testing
- intensive nutrition counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Ege University
Malnutrition Elderly, Primary Care
Brief Training Program for General Practitioners on Malnutrition and Adapted Physical Activity
This randomized, parallel-group interventional study evaluated the impact of brief targeted training on general practitioners' knowledge and professional practices regarding malnutrition and adapted physical activity (APA).
- Conditions
- Malnutrition Elderly, Primary Care, General Practitioner Education, Older Adults (65 Years and Older)
- Trial name
- NCT07794657
- Testing
- Malnutrition training, Adapted physical activity training
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Nantes University Hospital
Frailty, Older People
Sense of Control in Frail Older Persons
The proposed study seeks to explore the lived experience of control and wellbeing of older people diagnosed with frailty within the care service provision in southern England.
- Conditions
- Frailty, Older People, Sense of Control
- Trial name
- CONtrol (NCT04503811)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Bournemouth University
Older People, Frailty
A Technology-based Intervention to Support Older Adults in Living Independently
The general objective of this study is to test the usability and efficiency of the SAVE prototype, a technology-based support for enabling older adults to keep their independent and active lives in their homes and maintain their…
- Trial name
- SAVE (NCT05626556)
- Testing
- SAVE system
- Where
- 3 sites in Hungary, Italy and 1 more
- Volunteers
- 80 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Pulmonary Arterial Hypertension, Frailty
Safety and Impact of Low Resistance Exercise Training on Quality of Life in Pulmonary Arterial Hypertension
The purpose of the study is to learn more about how low-resistance training impacts frailty and the quality of life of people with pulmonary arterial hypertension (PAH).
- Trial name
- RESIST-PH (NCT06543745)
- Testing
- Low-Resistance Training
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Pennsylvania
Frailty in Older Adults, All Cause Mortality
Postoperative Frailty Trajectories and One-Year Mortality in Older Surgical Patients
Frailty is a key predictor of adverse outcomes in older surgical patients, yet its longitudinal evolution and potentially reversible nature remain underexplored in perioperative settings.
- Conditions
- Frailty in Older Adults, All Cause Mortality, Trajectory
- Trial name
- NCT07322809
- Where
- China
- Volunteers
- 4,417 people
- Sponsor
- Chinese PLA General Hospital
Aging
Trial of the Impact of the Electronic Frailty Integrated With Social Needs
Participants in Electronic Frailty Integrated with Social Needs (eFRIEND) will randomize to receive regularly scheduled in-person and telehealth contacts with a community health worker (CHW) or continue to receive standard of…
- Trial name
- NCT05293730
- Testing
- eFRIEND, Usual Care
- Where
- United States
- Volunteers
- 2,050 people
- Sponsor
- Wake Forest University Health Sciences
Sarcopenia
Exercise Intervention for Patients With Sarcopenia or Frailty in Long-term Care Institutions
Sarcopenia is a geriatric syndrome of decreased muscle volume with muscular function decline. There is more tendency for sarcopenic elderly to be frail, disabled, or have cardiovascular disease.
- Trial name
- NCT03650907
- Testing
- Group exercise program, Self exercise program
- Where
- Taiwan
- Volunteers
- 52 people
- Sponsor
- Chang Gung Memorial Hospital
Cardiac Arrest, Frailty
The Impact of Frailty on Cardiopulmonary Resuscitation Adverse Outcomes in Patients Requiring Code Blue Activation
The aim of this study was to determine the independent association of frailty with cardiopulmonary resuscitation and predictive factors in patients triggering code blue response
- Conditions
- Cardiac Arrest, Frailty, Respiratory Arrest
- Trial name
- NCT06405581
- Testing
- Edmonton frailty scale calculation
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Umraniye Education and Research Hospital
Cognitive Frailty
Chair Exercise and Intergenerational Activities in Older Adults With Physio-Cognitive Decline Syndrome
The goal of this clinical trial is to investigate the effects of chair exercise followed by intergenerational activity in frailty syndrome and changes in serum mBDN levels among older adults with Physio-Cognitive Decline Syndrome…
- Trial name
- PCDS (NCT07335978)
- Testing
- Intervention 1
- Where
- Indonesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Atma Jaya Catholic University of Indonesia
Coronavirus Infection, Sars-CoV2
Outcomes in Hospitalized Older Patients With COVID-19
In December 2019, the first patients infected with the 2019 novel coronavirus (2019-nCoV) were diagnosed in Wuhan. The clinical presentation and course of Severe Acute Respiratory Syndrome-CoV-2 (SARS-CoV-2) infection is poorly…
- Conditions
- Coronavirus Infection, Sars-CoV2, Elderly Infection, Old Age; Debility
- Trial name
- NCT04385212
- Where
- Switzerland
- Volunteers
- 230 people
- Sponsor
- University Hospital, Geneva
CGA, Comprehensive Geriatric Assessment
Exploring the User Experience of CGA-Q
As people become older they may start to have more than one health issue at one time. Geriatricians are doctors who specialise in looking after older people.
- Conditions
- CGA, Comprehensive Geriatric Assessment, Person Centred Care, Frailty
- Trial name
- NCT06646575
- Testing
- Qualitative data, no intervention
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Frailty, Aging
Phase I: Safety and Efficacy of an Injectable Follistatin Plasmid Gene Therapy in Humans
This study examines the safety and effects of an injectable plasmid gene therapy. Plasmids are circular pieces of DNA which have been widely studied as a non-permanent \& non-heritable method for transferring genes and inducing…
- Trial name
- NCT06411366
- Testing
- Follistatin plasmid
- Where
- Honduras
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Minicircle