Clinical trials: Frailty at Older Adults
Age Problem, Old Age; Debility
Swedish Palliative Care Guide (S-PCG) at Nursing Homes
Palliative care aims to improve the quality of life for patients and families who are affected life-threatening, incurable disease. The care should be person-centred, but it is not entirely clear how this is best achieved.
- Conditions
- Age Problem, Old Age; Debility, Dementia
- Trial name
- NCT06431659
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Region Skane
Hip Fracture Surgeries, Geriatric Assessment
ASA or CFS for ICU Prediction in Geriatric Hip Fracture
The aim of this retrospective study is to compare the efficacy of the American Society of Anesthesiologists (ASA) physical status classification and the Clinical Frailty Scale (CFS) in predicting postoperative intensive care unit…
- Conditions
- Hip Fracture Surgeries, Geriatric Assessment, Frailty at Older Adults, Intensive Care
- Trial name
- NCT07522541
- Testing
- Routine Surgical and Anesthetic Mnagement.
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Frailty, Emergency Department Visit
Association Between Geriatric Frailty and Medication Related Problems in the Emergency Department to Help Clinical Pharmacists Prioritise Patients
The healthcare systems are under increasing pressure due to a rise in emergency consultations, staff shortages, an ageing population and rising costs.
- Conditions
- Frailty, Emergency Department Visit, Elderly, Drug Drug Interaction
- Trial name
- DISARMED (NCT07282379)
- Testing
- Pharmaceutical analysis based on the Electronic Patient Record
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Pharmacie des Hopitaux de l'Est Lemanique
Postoperative Delirium (POD), Frailty at Older Adults
Preoperative Lymphocyte-to-Monocyte Ratio and Postoperative Delirium by Frailty Status in Older Surgical Patients
Both frailty and a reduced preoperative lymphocyte-to-monocyte ratio (LMR) are known risk factors for postoperative delirium (POD). However, whether the relationship between LMR and POD varies by frailty status remains unclear.
- Conditions
- Postoperative Delirium (POD), Frailty at Older Adults, Lymphocyte
- Trial name
- NCT07322744
- Where
- China
- Volunteers
- 6,475 people
- Sponsor
- Chinese PLA General Hospital
Old Age; Debility, Loneliness
The Effect of Home Visit Supported Nursing Education Program on Some Parameters in Elderly People Living Alone at Home
It is aimed to develop healthy lifestyle behaviors of elderly people living alone at home, reduce their loneliness levels and increase their social support capacity.The research was planned as a quasi-experimental research.
- Conditions
- Old Age; Debility, Loneliness, Healthy Lifestyle
- Trial name
- NCT06517615
- Testing
- Home Visit Supported Nursing Training Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Protein Metabolism
Peanut Sip Feeding Protocol
Peanuts are considered a functional food and regular consumption is associated with positive health effects. Protein is the second most common nutrient in peanuts after fat.
- Trial name
- NCT06693544
- Testing
- Peanut protein
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Frailty at Older Adults
Enhancing Physical Reserve to Promote Resilience in Physically Frail Older Adults
The goal of this clinical trial is to assess the efficacy of combined aerobic and resistance training in enhancing physical reserve in older adults with physical frailty.
- Trial name
- MRI exercise (NCT07513701)
- Testing
- Aerobic and resistance training, Usual Care
- Where
- Hong Kong
- Volunteers
- 224 people
- Sponsor
- The Hong Kong Polytechnic University
Frailty at Older Adults, Ovarian Cancer
The Better, Harder, Faster, Stronger Study
The purpose of this study is to evaluate changes in the electronic Frailty Index (eFI) score following 3-4 cycles of neoadjuvant chemotherapy (NACT) in participants with advanced ovarian and endometrial cancer.
- Conditions
- Frailty at Older Adults, Ovarian Cancer, Endometrial Cancer, Cognitive Dysfunction
- Trial name
- NCT07220512
- Testing
- data collection
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Wake Forest University Health Sciences
Coronary Heart Disease
Improving Frailty in Patients With Stable Ischemic Heart Disease
The goal of this clinical trial is to improve the frailty in old patients who have a cardiac disease . Researchers will determine the improvement in the instability and the strength along twelve sessions based on guided exercises…
- Trial name
- FRAGICOR (NCT07373119)
- Testing
- physiotherapy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Frailty, Fall
Nicotinamide Supplementation Improves Physical Performance in Older Adults at Risk of Falls
Falls are unplanned events resulting in contact with a lower surface. They are common in older adults, affecting one in three individuals over 65 years old.
- Conditions
- Frailty, Fall, Frailty Syndrome, Falls
- Trial name
- NICE-FIT (NCT06465602)
- Testing
- Nicotinamide
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
Frail Elderly Syndrome
Frailty Assessment and Treatment Strategies in the Elderly at Risk of Functional Decline in the Community
This study aims to design a patient -centered program to prevent or delay frailty , functional decline and adverse events, and evaluates the effectiveness of the program with a randomized clinical trial.
- Trial name
- NCT03591055
- Testing
- CGA, medication review, exercise and cognitive stimulation
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Frailty, Geriatrics
Combating Hospital-related Function Decline Among Prefrail Older Adults: A Pilot Study
This study focuses on the "Strength-based Tailored-Exercise Program at Home (STEP@Home)" aimed at improving health outcomes for geriatric patients at risk of hospitalization-associated functional decline.
- Trial name
- STEP@Home (NCT06191276)
- Testing
- STEP@Home Intervention, Usual care
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong
Balance Impairment, Sarcopenia in Elderly
Multicomponent Exercise and Frailty in Nursing Home Residents
Frailty is common among older adults living in nursing homes and increases the risk of falls, disability, and loss of independence.
- Conditions
- Balance Impairment, Sarcopenia in Elderly, Frailty at Older Adults, Functional Decline
- Trial name
- BASE-Frail (NCT07686146)
- Testing
- Multicomponent Exercise Program (BASE), Usual Care
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Escoles Universitaries Gimbernat
Frail Elderly Persons
SUPPORT FOR FRAIL ELDERLY PERSONS - From Prevention to Palliation
The present study "Elderly person in the risk zone" form part of the research programme "Support for frail elderly persons - from prevention to palliation" (www.
- Trial name
- NCT00877058
- Testing
- preventive home visit, senior meetings
- Where
- Sweden
- Volunteers
- 459 people
- Sponsor
- Vardalinstitutet The Swedish Institute for Health Sciences
Postoperative Mortality, Frailty at Older Adults
Predictive Value of Frailty Scores and Admission Laboratory Markers for Postoperative ICU Mortality
This prospective observational study aims to evaluate the predictive value of the Clinical Frailty Scale (CFS), the Katz Activities of Daily Living (ADL) scale, and admission laboratory markers for postoperative mortality among…
- Conditions
- Postoperative Mortality, Frailty at Older Adults, Activities of Daily Living, Postoperative Complications
- Trial name
- GERI-MORTAL (NCT07279519)
- Where
- Turkey (Türkiye)
- Volunteers
- 393 people
- Sponsor
- Malatya Egitim Ve Arastirma Hastanesi
Dance, Older Adults
Dose-response Effect of Community Dance Programme
The goal of this interventional study is to examine the dose-response effect of Community Dance Programme (CDP) on the physical, cognitive and psychological health of pre-frail and mildly frail community-dwelling older adults.
- Conditions
- Dance, Older Adults, Frailty at Older Adults, Active Ageing
- Trial name
- NCT07081191
- Testing
- Dance, Active Control
- Where
- Singapore
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Frailty
Prevalence of Frailty Among People Aged 75 and Over Living at Home
The aging of population lead to study ways to prevent dependence. Frailty is a precursor to dependence which can be reversible. In the literature, estimate of prevalence of frailty is highly variable depending on the frailty…
- Trial name
- FRAIL-DOM (NCT05163457)
- Testing
- Data collection
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Université de Reims Champagne-Ardenne
Arthritis, Cancer
MoveStrong at Home: A Feasibility Study of a Model for Remote Delivery of Functional Strength and Balance Training Combined With Nutrition Education for Older Pre-frail Adults.
Sufficient muscle strength helps to get out of a chair and can prevent falls. Up to 30% of older adults experience age-related loss of muscle strength, which can lead to frailty and health instability.
- Conditions
- Arthritis, Cancer, Cardiovascular Diseases, Chronic Lung Disease
- Trial name
- NCT04663685
- Testing
- Exercise program, Nutrition education
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
Frailty at Older Adults, Post-Traumatic Stress Disorder in Old Age
Multimodal Intervention for Older Adults After an Earthquake
This randomized controlled study was conducted among older adults (≥65 years) living in temporary container housing in Kahramanmaraş after the February 2023 earthquakes.
- Conditions
- Frailty at Older Adults, Post-Traumatic Stress Disorder in Old Age, Depression in Adults, Malnutrition Elderly
- Trial name
- NCT07273253
- Testing
- Multimodal intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Postoperative Delirium (POD), Frailty at Older Adults
Associations of Postoperative Delirium With Perioperative Frailty Worsening and Their Combined Effect on 1-Year Mortality in Older Surgical Patients
Postoperative delirium (POD) is a frequent complication in older surgical patients and is associated with adverse outcomes, while frailty is also highly prevalent during the perioperative period.
- Conditions
- Postoperative Delirium (POD), Frailty at Older Adults, Mortality, Recovery of Function
- Trial name
- NCT07259850
- Where
- China
- Volunteers
- 6,196 people
- Sponsor
- Chinese PLA General Hospital