Clinical trials: Free Fibular Flap
Skin Graft Complications
Factors Affecting Split Thickness Skin Graft Success Rates in Patients Who Underwent a Radial Forearm or Fibula Free Flap
Fibula free flaps (FFF) and radial forearm free flaps (RFFF) are necessary to reconstruct parts of the face after cancer surgery, traumas, or debilitating infections.
- Trial name
- NCT04648267
- Testing
- Cast and bolster placement duration, Standard of care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Southern California
Carcinomatous Resections, Violent Trauma
Evaluation of the PICO® Negative Pressure Dressing System on the Fibula Free Flap Donor Site's Skin Graft.
A fibula free flap can be used for the reconstruction of a mandible or a maxillar when the lack of bonne exceeds 3cm. This flap is made of the fibula bone, some muscle around, the fibular vascular pedicle and a skin paddle to…
- Trial name
- PICOFLAP (NCT04628416)
- Testing
- PICO dressing, Conventional dressing
- Where
- France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Montpellier
Head and Neck Cancer, Pain, Musculoskeletal
Continous Popliteal Block for Microvascular Free Flap Reconstruction in Ear, Nose and Throat Surgery
The aim of the study is to assess the effects of a continuous popliteal block on postoperative pain and recovery after major ear, nose and throat surgery with microvascular free flap reconstruction using a fibula graft.
- Trial name
- NCT03607227
- Testing
- Levobupivacaine, Saline Solution
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Region Skane
Mandibular Reconstruction
Evaluation of an Universal Surgical Device for Mandibular Reconstruction.
Fibula free flap is the gold standard for mandibular reconstruction. The shape of the fibula requires osteotomy that can be performed with a custom surgical guide.
- Trial name
- FIBUMAND (NCT06238076)
- Testing
- Universal surgical device FIBUMAND
- Where
- France
- Volunteers
- 19 people
- Sponsor
- University Hospital, Toulouse
Tibial Fractures
Results of Cross-leg Free Vascularized Fibular Graft
This study aims to evaluate the new technique of cross-leg vascularized fibular graft for reconstruction of post-traumatic long tibial bone defects in terms of restoring normal anatomy and function of the traumatized limb in a…
- Trial name
- NCT06491316
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Assiut University
Mandible Reconstruction
Comparaison of the Accuracy of Immediate Fibula Reconstruction With Implants in Fresh Versus Delayed Cases
The goal of this clinical trial is to learn if mandibular reconstruction with immediate dental implants is as accurate in fresh cases and delayed cases The accuracy of the fibular segments and dental implants will be compared in…
- Trial name
- NCT07452315
- Testing
- fibula free flap
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Head and Neck Cancer
Survival Analysis of Oral Cancer Patients
This study aims to assess the survival rate of oral squamous cell carcinoma (OSCC) patients following immediate mandibular reconstruction with vascularized fibula flap (VFF) and to identify risk factors influencing the overall…
- Trial name
- NCT04967638
- Testing
- tumor resection and mandible reconstruction
- Where
- Belgium
- Volunteers
- 74 people
- Sponsor
- KU Leuven
Head and Neck Cancer
Functional and Aesthetic Outcomes After Mandible Reconstruction With Fibula Osteomyocutaneous Free Flaps
The purpose of this study is to assess the functional and esthetic outcomes in patients who had removal of a part of the lower jaw bone due to mouth cancer and reconstruction of the jaw bone with a bone ( fibula) from the leg at…
- Trial name
- NCT02572869
- Testing
- physical exam, questionnaires
- Where
- 3 sites in United States
- Volunteers
- 26 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Mandible Reconstruction
Assessment of Facial Symmetry Following Fibula Free Flap Fixated in a Prosthetically Favorable Position Versus the Inferior Border Position for Mandibular Reconstruction
The study aims to evaluate facial symmetry outcomes after mandibular reconstruction using fibula free flaps, comparing two fixation techniques: the prosthetically favorable position (alveolar level) and the conventional position…
- Trial name
- NCT06790628
- Testing
- Fibula free flap
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Cairo University
Bone Reconstruction by Free Fibula Flap
Functional Impact of Reconstructive Surgery by Harvesting a Vascularized Free Fibula Flap Postoperatively.
The fibula is a leg bone that can be used in complex bone reconstruction by reconstructive surgery. This innovative surgical procedure is increasingly used in complex facial (mandibular) reconstructions following cancer and…
- Trial name
- FIBULAM (NCT05641597)
- Testing
- Actimetric measurement, Evaluation of plantar flexion, dorsal flexion and ankle eversion forces, Assessment of static and dynamic balance and quality of life
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Operation Time, Complication of Surgical Procedure
CAS Versus Traditional Freehand Technique for Mandibular Reconstruction With Free Vascularized Fibular Flap
A total of 153 patients who underwent mandibular reconstruction by VFF were included from Jan 1999 to Dec 2019. The mandibular resection and reconstruction were performed by four experienced oral and maxillofacial surgeons.
- Trial name
- NCT04965441
- Testing
- Computer-assisted surgery
- Where
- Belgium
- Volunteers
- 153 people
- Sponsor
- KU Leuven
Microvascular Free Flap Transfer, Fibula Flap
Artificial Intelligence-Enabled Skin Perforator Segmentation
Computer-assisted surgery has revolutionized reconstruction with more efficient, accurate, and predictable surgery, as reported in our previous studies.
- Trial name
- NCT06634472
- Testing
- artificial intelligence
- Where
- Hong Kong
- Volunteers
- 49 people
- Sponsor
- The University of Hong Kong
Mandibular Tumors
Aesthetic Reconstruction of Onco-surgical Mandibular Defects Using FFF With and Without CAD/CAM Customized Cutting Guide
The purpose of this study is to compare Aesthetic results and operation time of free fibular flap with and without CAD/CAM customized osteotomy guide for reconstruction of mandibular defects.
- Trial name
- NCT03757273
- Testing
- FFF with CAD/CAM customized cutting guide, FFF without customized cutting guide
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
3d Printing, Facial Symmetry
Whole vs Segmented 3D Models for Mandibular Reconstruction
Three-dimensional (3D) printing is increasingly used in surgery to help doctors plan and perform complex operations with greater accuracy.
- Conditions
- 3d Printing, Facial Symmetry, Free Fibular Flap, 3d Model
- Trial name
- NCT07365085
- Testing
- 3D-printed surgical guide - segmented model, 3D-printed surgical guide - whole mandible model
- Where
- Indonesia
- Volunteers
- 36 people
- Sponsor
- Universitas Indonesia
Bone and Joint Infection
Infection After Free Fibula Flap Reconstruction of the Mandible: a Retrospective Cohort Study
Mandibular osteitis after flap reconstruction is rare but is a serious infection with significant sequelae. The aim of this study is to describe this type of infection
- Trial name
- FibFlapI (NCT04373278)
- Testing
- failure of reconstruction of the mandibule by free fibula flap
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Reconstructed Jaws, Free Fibula Flaps
Assessment of the Stability of Immediately Loaded All-on-four Dental Implants in FFF Used for Reconstruction of the Jaws
The use of free vascularized fibula flaps for bony reconstruction has proved its success as a substitution for the resected bone and in some instances, the surrounding soft tissues The aim of this case series study is to evaluate…
- Conditions
- Reconstructed Jaws, Free Fibula Flaps, All on Four Technique
- Trial name
- NCT03950284
- Testing
- immediate loading with all on four technique in FFF
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Anesthesia, Local, Surgery
Regional Anesthesia Block in Fibula Free Flap Reconstruction
Despite many recent advances in pain management, post-operative pain is widely considered to be poorly managed. Furthermore, the mainstay of current pain management is opioids, for which there is strong evidence of ill effects…
- Conditions
- Anesthesia, Local, Surgery, Opioid Use, Pain, Postoperative
- Trial name
- NCT03906838
- Testing
- Ropivacaine injection
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Mandibular Neoplasms
Virtual Surgical Planning Systems in Mandibular Reconstruction
The purpose of this study was to evaluate the accuracy of virtual planning using customized surgical devices (VP3D) in fibula free flap mandibular reconstruction.
- Trial name
- VP3D (NCT03869723)
- Testing
- Virtual planning using customized surgical devices, Conventional surgery
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Fibula / Surgery, Surgical Flaps
Novel Application of a Low-cost Alternative to Patient Specific Implants (PSI) in Mandibular Free Fibula Flap Reconstruction by Reverse Engineering of Stock Plates: A Pilot Validation Study
Stock reconstruction plates have been used for decades and represent a tried-and-true alternative to custom plating. Stock plates are readily available, are cost effective, and can be accurately bent before surgery, particularly…
- Conditions
- Fibula / Surgery, Surgical Flaps, Computer-Aided Design, Mandibular Reconstruction* / Methods
- Trial name
- NCT05672056
- Testing
- Computer guided placement of a stock plate pre-bent on a 3D printed model
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Tumor
Vascularized Free Fibula Flap and Computer-guided Implant Surgery
The rehabilitation of patients affected by defects of the jaws after tumor resection is still very challenging. Resection can lead to significant facial deformity, impaired oral functions such as speech, swallowing, saliva…
- Trial name
- NCT01561534
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University of Bari