Clinical trials: Frozen Embryos
Clinical Pregnancy
Immediate Versus Delayed Natural Cycle Frozen Embryo Transfers
Introduction: Based on recent studies the suggestion is that natural cycle frozen embryo transfers (NC FET) should preferably be used, with evidence suggesting that artificial cycle FET (AC FET) is subject to increased risks of…
- Trial name
- FET (NCT05215119)
- Testing
- natural cycle endometrial preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 818 people, healthy volunteers welcome
- Sponsor
- Antalya IVF
Infertility, Female Infertility
the Effect of Endometrial Compaction Caused by Progesterone Effect on Pregnancy Outcomes
The purpose of this prospective cohort study is to assess the effect of endometrial compaction caused by progesterone effect on pregnancy outcomes
- Conditions
- Infertility, Female Infertility, Frozen-thawed Embryo Transfer
- Trial name
- NCT04733235
- Testing
- Progesterone
- Where
- Turkey (Türkiye)
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Infertilities, Embryo Transfer
Impact of the Presence of the Corpus Luteum on Pregnancies Obtained Through Frozen Embryo Transfer(FET)
In pregnancies achieved through programmed frozen embryo transfer cycle (PC-FET) and modified natural frozen embryo transfer (mNC-FET), to determine whether there are differences in endothelial and placental function, maternal…
- Trial name
- LUTI (NCT06896617)
- Testing
- Estradiol + Progesterone, Ovitrelle ( Hcg 250 mcg)
- Where
- Spain
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
IVF
Serum Progesterone on the Day of Thawed Embryo Transfer and Pregnancy Rate After an Artificial Endometrial Preparation
To determine if different serum Progesterone levels on FET day are associated with different clinical pregnancy rates (CPR), and if increasing dosage of vaginal Progesterone in cases of lower serum Progesterone level on FET day…
- Trial name
- NCT04278508
- Testing
- Progesterone
- Where
- Israel
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Infertility
A Study:the Different Outcomes Between Natural Cycle and Hormone Replacement Cycle in FET
There are three main cycle regimens used for endometrial preparation for frozen embryo transfer（FET）: natural cycles (NC) with/without ovulation triggering, hormone replacement therapy cycles (HRT) in which the endometrium is…
- Trial name
- NCT01780558
- Testing
- natural cycles, estradiol and progesterone
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Endometrial Preparation, Frozen Embryo Transfer
Effect of Adding Sildenafil to Protocol of Endometrial Preparation in Outcome of Frozen-thawed Embryo Transfer Cycles
The target of this study was an estimate the result of sildenafil on ultrasonographic endometrial thickness, endometrial pattern investigation estrogen level on the day of progesterone administration, Implantation rate and…
- Trial name
- sildenafil (NCT01668446)
- Testing
- Sildenafil, estradiol valerat
- Where
- Iran
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- farzaneh hojjat
Pregnancy, In Vitro Fertilization
The Impact of Early Embryos Incubation on Pregnancy Rate in IVF
Frozen- thawed embryos obtained by IVF treatments are transferred to the uterus immediately following thawing or after incubation for additional 24-72 hours. The two methods are routine in IVF laboratories.
- Trial name
- IVF-2010 (NCT01287273)
- Where
- Israel
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Martha Dirnfeld
Infertility
Evaluation of Blastocyst Morphology and Quality in Patients With Embryo Transfer at the Blastocyst Stage
In this prospective study, the investigators aim to investigate the role of trophectoderm cells and inner cell mass cells on pregnancy outcomes in blastocyst transferred in-vitro fertilization pregnancy.
- Trial name
- NCT05510557
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Primary Infertility, Secondary Infertility
LANDA Embryo Freezing Technique.
The aim of this study is to track the outcome from the patients who had embryo cryopreservation as part of their Advanced Reproductive Technology (ART) treatment at West Coast Fertility Centers.
- Conditions
- Primary Infertility, Secondary Infertility, Genital Diseases, Male, Genital Diseases, Female
- Trial name
- Freezing (NCT01271400)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- West Coast Fertility Centers
Progesterone Supplementation
Optimal Length of Progesterone Supplementation Before the Transfer of Cryopreserved (Frozen)-Thawed Day 3 Embryos in an Artificial Cycle With Exogenous Estrogen and Progesterone
Cryopreserved-thawed embryos are often replaced in an artificial cycle, in which the endometrium is prepared by exogenous estrogen and progesterone with or without the use of GnRH agonist downregulation.
- Trial name
- PROFETA-3 (NCT01940653)
- Testing
- Progesterone
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle
Effects of Trophectoderm (TE) Biopsy on the Health and Development of Children Born After Preimplantation Genetic Testing (PGT) Cycles.
This study aims to investigate the effects of trophectoderm (TE) biopsy on the health and development of children born after preimplantation genetic testing (PGT) cycles.
- Conditions
- Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle, Assisted Reproduction Technologies, Postnatal Health
- Trial name
- NCT07349966
- Testing
- Questionnaire
- Where
- Italy
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Assisted Reproductive Technology, Freezing/Thawing Procedure
Study of the Impact of Freezing-thawing Procedures and the Prolonged Culture of Embryos on Epigenetic Regulation in Humans
For this project, 4 groups of 38 infants have been created so as to evaluate the impact of Assisted-Reproduction Technology (ART) and more particularly the two procedures classically used in ART: the freezing/thawing of embryos…
- Conditions
- Assisted Reproductive Technology, Freezing/Thawing Procedure, Prolonged Culture Procedure
- Trial name
- NCT02171884
- Testing
- Sample of cord blood, Sample of placenta
- Where
- 2 sites in France
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Pregnancy
Down-regulated Hormonally Controlled Cycles for Vitrification-warmed Blastocyst Transfers
Currently all patients that have freeze-all ICSI treatment cycles have the start of their FET cycle scheduled with the use of OCP.
- Trial name
- NCT02238431
- Testing
- Lucrin depot, OCP, Natural
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Antalya IVF
Infertility, Female, Infertility of Uterine Origin
Progesterone Levels and Endometrial Compaction in Frozen-Thawed Embryo Transfer Cycles
This study is intended to determine whether there is a correlation between endometrial compaction and serum progesterone levels on the day of frozen embryo transfers by using transvaginal sonography for the endometrial assessment.
- Conditions
- Infertility, Female, Infertility of Uterine Origin, Implantation; Placenta
- Trial name
- NCT04554654
- Testing
- transvaginal ultrasound,
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cem Demirel
Female Infertility
Extended Culture of Day 3 to Day 5 Frozen Thawed Day 3 Embryos Versus Day 5 Frozen-Thawed Embryos
Cryopreservation of embryos and oocytes has become routine in assisted reproduction technology (ART). Live birth rates following frozen embryo transfers have increased significantly.
- Trial name
- NCT05858333
- Testing
- Extended culture for Group 2: (day 3-5 group)
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
ART, IVF
Health in Childhood Following Assisted Reproductive Technology
The purpose of this trial is to investigate the metabolic and cardiovascular health in children aged 6-8 years born after in-vitro fertilization with frozen embryo transfer
- Conditions
- ART, IVF, Cardiovascular Risk Factor, Hypertension
- Trial name
- HiCART (NCT03719703)
- Where
- Denmark
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Anja Bisgaard Pinborg
Infertility, Endometriosis
Comparison Elagolix vs Depot Leuprolide Prior to Frozen Embryo Transfers in Patients With Endometriosis
Patients who have been previously surgically diagnosed with endometriosis and have embryos predicted to be euploid after in vitro fertilization will be divided into 2 groups via randomization.
- Trial name
- NCT04445025
- Testing
- Elagolix 200 MG, Leuprolide Acetate 3.75 MG/ML, Lab work
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Colorado Center for Reproductive Medicine
Infertility
Assesment of Embryo Viability and Re-expansion After Thawing in Blastocyst Stage Embryos
In this prospective study, the possible effects of embryo viability and degree of blastocele re-expansion on pregnancy outcomes before vitrified/thawed blastocyst transfer will be evaluated.
- Trial name
- NCT05474833
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
IVF
Comparative Study Between Fresh and Frozen Embryo Transfer in PCOS Patients Undergoing IVF Treatment
The objective of our study is to compare in vitro fertilization (IVF) outcomes between fresh embryo transfer (ET) and frozen-thawed ET in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT05167838
- Testing
- fresh embryo transfer, Frozen embryo transfer
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infertility
Graduated Embryo Score (GES) in the Fresh Cycle Predicts Outcome From Frozen Embryo Transfer
Evaluation of embryo quality in the fresh cycle as a predictor of outcome from frozen embryo transfer.
- Trial name
- GES/FET (NCT00694434)
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Sher Institute for Reproductive Medicine, Las Vegas