Clinical trials: Frozen Embryos
Infertility, Female, Anxiety State
Women's Quality of Life, Sexual Life and Psychological State in Patients Undergoing Embryo Transfers
Women's quality of life, sexual life and psychological state would affect the success of embryo transfer. The primary purpose of the study is to compare women's quality of life, sexual life and psychological state using validated…
- Conditions
- Infertility, Female, Anxiety State, Depression, Quality of Life
- Trial name
- NCT04131452
- Testing
- Filling out the forms including IDAS-II, BAI, SF-36 and FSFI
- Where
- Turkey (Türkiye)
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Bahceci Health Group
Pregnancy Related, Infertility, Female
Comparison of Live Birth Rate in Natural Cycle Single Euploid FET Versus Without Luteal Phase Support
To evaluate whether single euploid embryo transfer in NC without routinely administered LPS is non-inferior to NC with routinely administered LPS.
- Trial name
- NCT05969795
- Testing
- Transvaginal ultrasound, Serial serum LH, E2, P4, Progesterone 100 Mg Vaginal Insert
- Where
- 3 sites in United Arab Emirates
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility
Intrauterine Injection of Human Chorionic Gonadotropin Injection (hCG) Before Embryo Transfer on Pregnancy Outcomes in Frozen Embryo Transfer Cycles.
The present study is designed as a pilot study with 50 patients in each group. Data collection form will be filled by the researcher who does not know the type of intervention in each group
- Trial name
- NCT02825108
- Testing
- Intra uterine injection of tissue culture medium containing HCG+ET, Intra uterine injection of tissue culture medium +ET, ET
- Where
- Iran
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Luteal Phase Defect
Progesterone Levels and Clinical Outcomes Using a Single Pessary of 400 mg of Vaginal Progesterone in Substitutive Cycles for Embryo Transfer.
This study aims to compare the efficacy, in terms of progesterone levels and clinical outcomes, of two different presentations of micronized vaginal progesterone (400 mg vs.
- Trial name
- CycloCT (NCT04722471)
- Testing
- Vaginally administered progesterone
- Where
- Spain
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Obesity, Maternal
The Application of HCG in Luteal Support for Frozen Embryo Transfer in Ovulation Cycle of Obese Women
This study aims to explore whether the application of low-dose HCG in luteal support can improve the pregnancy outcomes of natural cycle frozen embryo transfer in obese patients
- Trial name
- NCT07633002
- Testing
- Human Chorionic Gonadotropin
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Shandong University
ART, IVF
Cardiometabolic Function in Offspring, Mother and Placenta After Assisted Reproductive Technology
The overall objective is to establish the first-of-its-kind longitudinal cohort of pregnant women, biological fathers/partners and offspring from pregnancies achieved by frozen embryo transfer (FET), fresh-embryo transfer (fresh…
- Conditions
- ART, IVF, Children, Only, Cardiovascular Disease Other
- Trial name
- COMPART (NCT06334003)
- Where
- 3 sites in Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
ART
Oral Dydrogesterone vs. Vaginal Micronized Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer
The current trial is intended to assess the efficacy of oral versus vaginal progesterone for luteal support in frozen IVF cycles.
- Trial name
- NCT03832699
- Testing
- Dydrogesterone 10 MG, Endometrin 100Mg Vaginal Insert
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Recurrent Implantation Failure in Setting of Artifically Prepared Endometrium
Trial of Endometrial Scratch Prior to Frozen Embryo Transfer in Patients With Recurrent Implantation Failure
Patients with a history of recurrent implantation failure who are planning a frozen embryo transfer (FET) are enrolled into the program.
- Trial name
- NCT03157765
- Testing
- endometrial biopsy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brown Fertility
Infertility, Female, Polycystic Ovary Syndrome
Letrozole for Frozen Embryo Transfer (FET) in Patients With Polycystic Ovary Syndrome (PCOS)
To offer patients with oligomenorrhoea or amenorrhoea an alternative to frozen embryo transfer in an artificial cycle, endometrial preparation using letrozole may be a valuable option.
- Conditions
- Infertility, Female, Polycystic Ovary Syndrome, IVF, Ovulation Disorder
- Trial name
- LEFT (NCT04002635)
- Testing
- Letrozole, estradiol valerate
- Volunteers
- healthy volunteers welcome
- Sponsor
- CRG UZ Brussel
Cleavage Stage, Ovum
Vitrification Versus Slow Freezing of Human Day 3 Embryos
In assisted reproduction technology (ART), cryopreservation of embryos maximizes the potential of IVF cycles. Currently different cryopreservation methods are used, the conventional slow freezing method and vitrification.
- Trial name
- NCT00710723
- Testing
- vitrification
- Where
- Belgium
- Volunteers
- 901 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
IVF, Frozen Embryo Transfer (FET)
Maternal Cardiovascular Adaption to Pregnancy in IVF Patients Following Frozen Embryo Transfer (FET)
Aim of the study is to explore the effect of a lacking corpus luteum on maternal cardiovascular and metabolic adaption to pregnancy by the use of magnetic resonance imaging (MRI).
- Conditions
- IVF, Frozen Embryo Transfer (FET), Cardiovascular Adaption, Magnetic Resonance Imaging (MRI)
- Trial name
- NCT06471140
- Testing
- magnetic resonance imaging (MRI)
- Where
- Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Infertility
Frozen Embryo Donation Study
The purpose of this study is to improve patient understanding of and interest in donating frozen embryos resulting from in vitro fertilization (IVF) to others undergoing infertility treatment.
- Trial name
- FREDS (NCT01883934)
- Testing
- Enhanced clinic-based support/counseling, Control
- Where
- United States
- Volunteers
- 3,568 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Pregnancy Loss, Frozen Embryo Transfer
Substituted Frozen Embryo Transfer Cycles With GnRH-agonist Supplementation
The aim of this study is to compare two FET protocols by modifying the substituted FET cycle in order to maintain a higher ongoing positive pregnancy rate and thus reduce the early pregnancy loss.
- Trial name
- NCT01943812
- Testing
- Estradiol and progeterone
- Where
- 2 sites in Denmark
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Infertility, Female
Effect of Oxytocin Antagonists on Implantation Success Rates of Frozen-thawed Embryo Transfer
Uterine contraction has a negative impact on implantation and pregnancy rates. Inhibition of oxytocin receptors decreases uterine contraction frequency both on pregnant and non-pregnant women.
- Trial name
- NCT03904745
- Testing
- Atosiban
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Infertility
Frozen Embryo Transfer (FET) in Natural Cycles or in Natural Cycles Controlled by Human Chorionic Gonadotropin (hCG) Administration
The rational of the study is to assess the implantation, pregnancy and live birth rates after the transfer of frozen- thawed embryos in natural cycles with spontaneous Luteinizing Hormone (LH)/Progesterone rise or in natural…
- Trial name
- FRET (NCT00809107)
- Testing
- HCG
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, Female Infertility
What is the Optimal Cycle Regimen for Frozen- Thawed Embryo Transfer Cycles
Investigators will be comparing artificial (HRT) frozen-thawed embryo transfer cycles to correctly conducted spontaneous natural cycles after the transfer of a chromosomally normal embryo.
- Conditions
- Infertility, Female Infertility, Pregnancy Early
- Trial name
- NCT03954587
- Where
- United Arab Emirates
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility, Female
Impact of Endometrial Compaction in Euploid Frozen Embryo Transfers
The purpose of this pilot study is to evaluate whether a decrease in endometrial thickness (compaction) prior to progesterone exposure (endogenous or exogenous) to the day before a single frozen embryo transfer has an impact on…
- Trial name
- NCT04330066
- Testing
- Abdominal ultrasound measurement of the endometrial lining
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Infertility, IVF
Health of Frozen Transferred Versus Fresh Transferred Children
In order to give strong recommendation on the efficacy and safety of fresh versus frozen embryo transfer, we conduct this study in order to investigate the physical and mental development of children from fresh versus frozen…
- Trial name
- NCT04099784
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Endometrium
The Effect of Tamoxifen on Clinical Outcome in Women With Thin Endometrium Undergoing Frozen Thawed Cycle.
Cryopreservation of embryos created during fresh IVF cycles provides a less expensive and time-intensive opportunity for pregnancy. Ideal endometrium thickness is the key point to optimization FET cycle.
- Trial name
- NCT03060304
- Testing
- Tamoxifen, estradiol valerate
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Pregnancy
Idealizing Pregnancy Outcome With Single Blastocyst Transfer in a FET Cycle
Single embryo transfer (SET) has been advocated as a means of reducing the risk of multiple pregnancies, but has meant a reduction in pregnancy risk per embryo transfer.
- Trial name
- NCT01987856
- Testing
- Blastocyst morphology
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Antalya IVF