Clinical trials: Frozen Thawed Embryo Transfer
Embryo Transfer
Natural Versus Artificial Cycle for Frozen-Thawed Embryo Transfer
This study evaluates clinical pregnancy rates, obstetrical outcome parameters, costs and patient preferences in natural cycle versus artificial cycle frozen embryo transfers (FET).
- Trial name
- NAFT (NCT03642665)
- Testing
- Natural cycle, Estradiol Valerate, Micronized progesterone
- Where
- Belgium
- Volunteers
- 554 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Infertility
Comparison of Frozen-thawed Embryo Transfers and Fresh Embryo Transfers With Whole Chromosome Analysis Using Next Generation Sequencing
The investigators propose to perform a clinical randomized trial to evaluate the effect of a frozen-thawed embryo transfer and a fresh embryo transfer on pregnancy and implantation rates; with the added benefit of a blastocyst…
- Trial name
- NCT02000349
- Testing
- PGD
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Reprogenetics
In Vitro Fertilization, Subfertility
Hyaluronan-enriched Embryo Transfer Medium for Frozen-thawed Embryo Transfer
This is a randomized-controlled trial evaluating the effect of the use of hyaluronan (HA)-enriched embryo transfer medium on the live birth rate in women undergoing frozen-thawed embryo transfer.
- Trial name
- NCT02725827
- Testing
- EmbryoGlue (Vitrolife), Control medium
- Where
- 2 sites in Hong Kong
- Volunteers
- 550 people
- Sponsor
- The University of Hong Kong
Implantation; Placenta, Pregnancy Loss
Luteal Support in Frozen-Thawed Embryo Transfer Cycles
This study evaluates the clinical efficacy of 3 different luteal phase support in patients undergoing frozen-thawed embryo transfer cycles. Endometrium preparation will be hormone replacement in all cycles.
- Conditions
- Implantation; Placenta, Pregnancy Loss, Frozen Embryo, Luteal Support
- Trial name
- NCT03948022
- Testing
- Dydrogesterone 10Mg Tablet (duphaston), Progesterone 50Mg/mL Oil, Crinone 8% Vaginal Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Centrum Clinic IVF Center
Letrozole, Infertility, Female
The Effectiveness of the Letrozole-induced Endometrial Preparation Protocol in Frozen-thawed Embryo Transfer (FET)
The goal of this single center, non-blinded, randomized controlled clinical trial to comparison of pregnancy outcomes and perinatal outcomes in patients undergoing IVF treatment (including ICSI) with FET with letrozole-induce…
- Trial name
- NCT06006091
- Testing
- Letrozole
- Where
- China
- Volunteers
- 858 people
- Sponsor
- International Peace Maternity and Child Health Hospital
IVF
Serum Progesterone on the Day of Thawed Embryo Transfer and Pregnancy Rate After an Artificial Endometrial Preparation
To determine if different serum Progesterone levels on FET day are associated with different clinical pregnancy rates (CPR), and if increasing dosage of vaginal Progesterone in cases of lower serum Progesterone level on FET day…
- Trial name
- NCT04278508
- Testing
- Progesterone
- Where
- Israel
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Infertility
Availability of Poor Quality Embryos
The purpose of this study is to explore a method to identify the viability of day-3 poor quality embryos
- Trial name
- Availability (NCT01715545)
- Where
- China
- Volunteers
- 481 people
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Frozen Embryo Transfer
Assessment of Endometrial and Sub-endometrial Vascularity Before and After PRP Infusion in Frozen Embryo Transfer Cycles
A good quality embryo and receptive endometrium are important aspects in achieving optimal outcomes in assisted reproductive treatment (ART). Endometrial thickness is an important marker of uterine receptivity.
- Trial name
- NCT04247204
- Testing
- Platelet-rich plasma intrauterine infusion
- Volunteers
- 30 people
- Sponsor
- Hatem AbuHashim
In Vitro Fertilization
Replacement of Fresh Embryo Transfers (ETs) by Frozen Embryo Transfers (FETs) Using Vitrification
Cryopreservation of all embryos and transferring them subsequently in assisted reproductive technology (ART) cycles to improve outcome.
- Trial name
- NCT00823121
- Testing
- freezing embryos by vitrification, fresh embryo transfers, buserelin
- Where
- Iran
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yazd Research & Clinical Center for Infertility
Infertility, Female
Personal FET in RIF Patients According to Histological Dating of Endometrial of Natural/ Hormone Replacement Cycle
At present, the evaluation criterion of endometrial receptivity is controversial. The development of a molecular diagnostic tool, the endometrial receptivity array (ERA) for diagnosis of endometrial receptivity .
- Trial name
- NCT03312309
- Testing
- personal embryo transfer
- Where
- China
- Volunteers
- 155 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Infertility
Effect of Vaginal Sildenafil Citrate on Endometrial Preparation and Outcome in Frozen Thawed Embryo Transfer Cycles
A total of 80 Patients who meet these conditions will enter the study and be divided into two groups based on randomized tables.
- Trial name
- NCT03854175
- Testing
- sildenafil citrate, Estradiol Valerate 2 MG
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Frozen Embryo Transfer
Frozen-thawed Embryo Transfers and Hormone Substitution on Thrombotic Risk Markers
The study focus on the impact of estrogen/progesterone substitution during artificial cycle frozen embryo transfer (AC-FET) in women undertaking assisted reproductive technology treatment (ART).
- Trial name
- TromboFET (NCT04359576)
- Testing
- Primary and secondary hemostasis
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Horsens Hospital
ART
Oral Dydrogesterone vs. Vaginal Micronized Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer
The current trial is intended to assess the efficacy of oral versus vaginal progesterone for luteal support in frozen IVF cycles.
- Trial name
- NCT03832699
- Testing
- Dydrogesterone 10 MG, Endometrin 100Mg Vaginal Insert
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Fertility Agents, Female
hCG Supplementation in Frozen-Thawed Embryo Transfer Cycle
The implantation rate after frozen-thawed embryo transfer cycles depends mostly on the receptivity of the endometrium and the embryo quality.The effects of human chorionic gonadotropins (hCG) on the endometrium have been…
- Trial name
- NCT00398229
- Testing
- s.c. human chorionic gonadotropin (Ovitrelle)
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
Embryo Transfer, IVF
Effect of Pentoxyfilline on Endometrial Thickness and Frozen Embryo Transfer Outcomes
The aim of this work was to investigate the effect of different vasodilators as pentoxifylline in women with unexplained infertility using IVF
- Conditions
- Embryo Transfer, IVF, Infertility
- Trial name
- NCT07499817
- Testing
- pentoxifylline 400 mg, (control)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Polycystic Ovary Syndrome, Infertility
Live Birth After Fresh Embryo Transfer Vs Frozen-thawed Embryo Transfer in Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of childbearing age. However, the optimal infertility treatment for PCOS patients is still a matter of controversy.
- Trial name
- FreFro-PCOS (NCT01841528)
- Testing
- fresh embryo transfer, frozen-thawed embryo transfer
- Where
- 14 sites in China
- Volunteers
- 1,180 people
- Sponsor
- Zi-jiang Chen
Hormone Replacement Therapy, Estrogen
Estrogen Supplementation Mode in HRT-FET Cycle: a RCT
A systematic review and meta-analysis concluded that there is insufficient evidence to recommend one particular protocol for HRT with regard to pregnancy rates after frozen embryo transfer, and no comparison of estrogen dose or…
- Conditions
- Hormone Replacement Therapy, Estrogen, Live Birth Rate
- Trial name
- NCT04503915
- Testing
- different estrogen supplementation modes
- Volunteers
- 784 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Ovarian Hyperstimulation Syndrome, Infertility Drugs
Transfer of Fresh Versus Frozen/Thawed Embryos in IVF Cycles Where GnRH Agonist is Utilized for Oocyte Maturation.
It has been suggested that in IVF cycles where GNRH agonist is utilized for final oocyte maturation in patients at risk of ovarian hyperstimulation, pregnancy rates are reduced.
- Conditions
- Ovarian Hyperstimulation Syndrome, Infertility Drugs, Female
- Trial name
- NCT00365027
- Testing
- Delayed embryo transfer
- Sponsor
- HaEmek Medical Center, Israel
Thin Endometrium
a-PRP Intrauterine Instillation in Women With Thin Endometrium
This study sought to compare the endometrial thickness among infertile women with a history of thin endometrium together with previous cancellation from IVF/ICSI inspection of intrauterine instillation of autologous-PRP or no…
- Trial name
- PRP(a-PRP) (NCT06234540)
- Testing
- PRP, Standard treatment
- Where
- Thailand
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Infertility, Female
Personalized FET in RIF Patients With Displaced Dating
The endometrium becomes receptive as a result of a series of timed hormonal events during the menstrual cycle. The exposure of the endometrium to progesterone after ovulation initiates morphological and functional alterations…
- Trial name
- NCT03910582
- Testing
- personalized frozen-thawed embryo transfer, routine frozen-thawed embryo transfer
- Volunteers
- 117 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya