Clinical trials: Full Rotator Cuff Tear
Full-thickness Rotator Cuff Tear
Why Does my Shoulder Hurt? Understanding the Presence of Pain in Individuals With Full-thickness Rotator Cuff Tears
Full-thickness rotator cuff tears (FTRCT), defined as "through-and-through" tears of one of the shoulder tendons, affect up to 32% of the population (mostly individuals older than 50 years) and are one of the most painful and…
- Trial name
- NCT03857009
- Where
- Canada
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Laval University
Full Thickness Rotator Cuff Tear
Rehabilitation of Reconstructed Shoulder Rotator Cuff
The aim of this study to define the optimal rehabilitation for clients with full thickness rotator cuff reconstruction, with two goals: 1.
- Trial name
- NCT01499992
- Testing
- Standard physical therapy program PLUS aquatic physical therapy, standard care
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Rotator Cuff Tear
Elevated Plasma Levels of TIMP-1 in Patients With Rotator Cuff Tear
The aim of the study was to investigate the levels of matrixmetalloproteinases and their inhibitors in blood samples from patients with rotator cuff tears and compare with blood samples from healthy matched controls.
- Trial name
- NCT01562145
- Testing
- Blood sampling
- Where
- Sweden
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Rotator Cuff Syndrome, Rotator Cuff Injury
Allograft Reconstruction of Massive Rotator Cuff Tears vs Partial Repair Alone
The investigators hypothesize that the use of an allograft adjuvant to partial repair will lead to improved shoulder outcome measure scores compared to partial repair alone in massive rotator cuff tears.
- Conditions
- Rotator Cuff Syndrome, Rotator Cuff Injury, Disorder of Rotator Cuff, Full Thickness Rotator Cuff Tear
- Trial name
- NCT01987973
- Testing
- Partial Rotator Cuff Repair, Partial Rotator Cuff Repair with Allograft Augmentation
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Ivan Wong
Rotator Cuff Tear, Acromial Spur
Study Comparing Patient Function and Satisfaction With Arthroscopic Subacromial Decompression Before and After Repair of Complete Rotator Cuff Tears
The investigators aim to establish whether completing a subacromial decompression before or after repair of a complete rotator cuff tear has any clinical significance.
- Trial name
- NCT01430598
- Testing
- Rotator Cuff Repair and Subacromial Decompression, Questionnaire
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Ascension Health
Full Thickness Rotator Cuff Tear
Rehabilitation: Closed-Chain Exercises for Rotator Cuff Tears
A single arm design will be used to assess the feasibility and preliminary efficacy of a closed-chain rehabilitation protocol for patients with full thickness rotator cuff tears of the shoulder.
- Trial name
- CERCT (NCT02750176)
- Testing
- Closed chain exercises
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Southern California
Full Thickness Rotator Cuff Tear
Pilot Study of Augment Rotator Cuff for Surgical Treatment of Full Thickness Rotator Cuff Tears
Study Purpose: To evaluate the safety and performance of Augment Rotator Cuff as a primary surgical treatment for full thickness rotator cuff tears.
- Trial name
- NCT01256242
- Testing
- Augment Rotator Cuff, Standard Suture Repair
- Where
- 4 sites in Canada
- Volunteers
- 31 people
- Sponsor
- BioMimetic Therapeutics
Full-thickness Rotator Cuff Tears
Anatomic and Clinical Long-term Follow-up of Conservatively Treated Rotator Cuff Tears
Study population: Patients who have been treated with physiotherapy for a potentially repairable rotator cuff tear in the period from 2002 to 2005.
- Trial name
- NCT01829633
- Testing
- Physiotherapy
- Where
- Norway
- Volunteers
- 49 people
- Sponsor
- Vestre Viken Hospital Trust
Full-thickness Rotator Cuff Tear
InSpace™ System in Comparison to Best Repair of Massive Rotator Cuff Tear.
This is a post-marketing study to further assess the safety and effectiveness of the InSpace™ device implantation in comparison to surgical repair of full thickness Massive Rotator Cuff Tear .
- Trial name
- NCT02208440
- Testing
- Best Repair of torn Rotator Cuff, InSpace™ system
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- OrthoSpace Ltd.
Full-thickness Rotator Cuff Tear, Rotator Cuff Tendinitis
Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections
The purpose of this study is to compare the functional outcomes of patients with shoulder pathology treated with either ketorolac or corticosteroid injections, in a randomized double-blinded study.
- Trial name
- NCT04895280
- Testing
- Ketorolac, Marcaine, Kenalog
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Michael Khazzam
Rotator Cuff Injuries
A Phase I/III Clinical Study of TPX-114 for the Treatment of Full-Thickness Rotator Cuff Tear
Rotator cuff tear is one of the most common shoulder diseases and retears occur frequently after arthroscopic repair. Therefore, there is a growing need of new therapy to improve structural outcome.
- Trial name
- NCT03668028
- Testing
- TPX-114, Arthroscopic surgery
- Where
- 2 sites in South Korea
- Volunteers
- 93 people
- Sponsor
- Tego Science, Inc.
Full- Thickness Massive RCT (MRCT) of at Least 5 cm in Diameter Including Fatty Infiltration Grade III or IV
InSpace™ System in Comparison to Best Repair of Massive Rotator Cuff Tear.
This is a post-marketing study to further assess the safety and effectiveness of the InSpace™ device implantation in comparison to surgical repair of full thickness Massive Rotator Cuff Tear .
- Trial name
- NCT01890733
- Testing
- Best Repair of torn Rotator Cuff, InSpace™ system
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- OrthoSpace Ltd.
Rotator Cuff Tears
InSpace Accelerated Rehabilitation Study
This is a prospective, parallel group, open-label, multi- center, randomized study to assess two accelerated rehabilitation programs for use with the InSpace device in the treatment of full thickness Massive, Irreparable Rotator…
- Trial name
- iAccelerate (NCT05329584)
- Testing
- InSpace Subacromial Tissue Spacer
- Where
- 11 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Stryker Endoscopy
Rotator Cuff Tears, Rotator Cuff Tear Arthropathy
Bioinductive Patch for Full-Thickness Rotator Cuff Tears
The purpose of this randomized-controlled study is to compare outcomes of arthroscopic rotator cuff repair augmented with a Bioinductive Implant (study group) to standard arthroscopic rotator cuff repair (control group).
- Trial name
- NCT05439850
- Testing
- arthroscopic rotator cuff repair, Bioinductive implant, Ultrasound Imaging
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Henry Ford Health System
Full Thickness Rotator Cuff Tear
Latissimus Dorsi Tendon Transfer or Partial Arthroscopic Repair of Massive Rotator Cuff Tears
A massive tear of the rotator cuff is a debilitating condition that causes pain, significant impairments in strength, and resultant loss of activity of the affected arm.
- Trial name
- NCT01481480
- Testing
- Latissimus dorsi tendon transfer, Arthroscopic repair
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Unity Health Toronto
Rotator Cuff Injuries
REGENETEN™ Bioinductive Implant System in Full-thickness Tears
The study is designed to assess the safety and efficacy of Arthroscopic rotator cuff repair (ARCR) augmented with REGENETEN in subjects requiring full-thickness rotator cuff tear repair or revision repair versus Arthroscopic…
- Trial name
- REGENETEN (NCT04450342)
- Testing
- Arthroscopic rotator cuff repair with REGENETEN™ Bioinductive Implant augmentation, Arthroscopic rotator cuff repair, Arthroscopic rotator cuff repair for revision surgery
- Where
- 30 sites in United States, Australia and 6 more
- Volunteers
- 119 people
- Sponsor
- Smith & Nephew, Inc.
Full Rotator Cuff Tear, Microfracture Procedure
Combined Microfracture Procedure Promotes Tendon Healing
This study is a prospective randomized controlled study of Combined microfracture procedure promotes tendon healing during double raw repair for full tear rotator cuff.
- Conditions
- Full Rotator Cuff Tear, Microfracture Procedure, Double Raw Repair
- Trial name
- NCT05792202
- Testing
- microfracture procedure, only double raw repair
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Jishuitan Hospital
Rotator Cuff Tears, Microfractures
Microfracture Combined With Suture Bridge Technique Versus Greenhouse Technique in Treating of Rotator Cuff Injuries
Several biological augmentation procedures have recently been suggested to enhance tendon healing after Arthroscopic rotator cuff repair, such as marrow-stimulating technique with microfractures of the greater tuberosity.
- Trial name
- NCT04686968
- Testing
- Greenhouse Technique, Microfracture Combined With Suture Bridge Technique
- Volunteers
- 48 people
- Sponsor
- Beijing Jishuitan Hospital
Rotator Cuff Syndrome
A Pivotal Study to Assess the InSpace™ Device for Treatment of Full Thickness Massive Rotator Cuff Tears
A pivotal study to assess the safety and effectiveness of the InSpace™ device implantation in comparison to surgical partial repair of full thickness Massive Rotator Cuff Tear (MRCT).
- Trial name
- NCT02493660
- Testing
- InSpace sub-acromial tissue spacer system, Partial repair of rotator cuff
- Where
- 21 sites in United States, Canada
- Volunteers
- 184 people
- Sponsor
- OrthoSpace Ltd.
Full Rotator Cuff Tear, Microfracture Procedure
Does Medial Raw Anchor Necessary During Tendon Repair Combined With Microfracture
This study is a prospective randomized controlled study of rotator cuff repair with lateral raw or double raw combined with microfracture procedure.
- Conditions
- Full Rotator Cuff Tear, Microfracture Procedure, Double Raw Repair, Lateral Raw Repair
- Trial name
- NCT06431191
- Testing
- lateral raw, double raw
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Jishuitan Hospital