Clinical trials: Functional Ability
Cognitive Ability, General
Cybercycling for Cognitive Health
Exercise has been linked to cognitive health, but few older adults exercise at recommended levels. Cybercycling may provide additional cognitive benefits due to increased motivation to ride the interactive 3D tours.
- Trial name
- NCT01167400
- Testing
- Cybercycling, Traditional exercise
- Where
- 8 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Union College, New York
MCI, MCI-AD, Early Stage Alzheimer's Disease
Efficacy and Safety of Dimethyl Fumarate Among Patients with Mild Cognitive Impairment and Dementia Due to Alzheimer's Disease
The goal of this clinical trial is to assess the degree of improvement in cognitive functions, including memory, attention, thinking, executive and language functions in diagnosed patients MCI and AD taking dimethyl fumarate 480…
- Conditions
- MCI, MCI-AD, Early Stage Alzheimer's Disease, Alzheimer's Disease
- Trial name
- NCT06850597
- Testing
- dimethyl fumarate
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Performance Enhancement
CAF & Firefighters Performance
The aim of the study being to investigate chewing caffeine-containing gum could effectively improve firefighters' balance under conditions of brain fatigue.
- Trial name
- CAF & FFT (NCT07570030)
- Testing
- Caffeine (300 mg)
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Chih-Hui Chiu
Heat Stress, Physiological Stress
Suitability of the 26 °C Indoor Temperature Upper Limit for Older Adults: Impacts of Clothing and Daily Activity
While an upper limit of 26°C has been shown to be protective for heat-vulnerable older occupants (DOI: 10.1289/EHP11651), this recommendation did not consider the added heat burden associated with increases in internal heat…
- Trial name
- NCT07189507
- Testing
- Simulated indoor temperature upper limit
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Chronic Cough (CC), Healthy Adult Participants
Impact of Refractory Chronic Cough on Activities of Daily Living and Response to Acute High-intensity Exercise
Chronic cough is a common and debilitating condition that affects up to 10% of the global population. The health impact of chronic cough is multifaceted and manifests both physical and psychological symptoms including syncope…
- Trial name
- NCT06766175
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Physical Inactivity, Aging
Motivating Activity Through Text Communications - Helping Adults Increase Movement
The goal of this clinical trial is to compare the effect of different types of text messages on physical activity levels of middle-aged and older adults and to determine whether these messages are effective in adults age 40 and…
- Conditions
- Physical Inactivity, Aging, Cognitive Ability, Behavior Change
- Trial name
- MATCH AIM (NCT07593677)
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Obstructive Pulmonary Disease
The Differences of Muscle Activity Between Patients With COPD and Healthy Adults
The purpose of this study attempts to investigate the differences and relationships of respiratory parameters, muscle activity, and dyspnea during ADL between patients with COPD and age-matched healthy participants.
- Trial name
- NCT04146948
- Testing
- no intervention
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Socioemotional Development, Cognitive Ability
Early Institutionalization Intervention Impact Project
The purpose of this study is to determine the effects of early intervention (placement into foster care, and a caregiving training) on physical, cognitive, social and brain development and psychiatric symptomatology in children…
- Conditions
- Socioemotional Development, Cognitive Ability, Behavioral and Neural Patterns of Attention, Brain Function
- Trial name
- EI-3 (NCT04165746)
- Testing
- Foster Care, Caregiving Intervention
- Where
- Brazil
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Electric Impedance, Healthy Volunteers
An Investigation Into an Objective Measure of Muscle Quality, Function and Ability
The assessment of muscular function, quality and ability is of high importance in a diverse range of clinical disciplines from anaesthetics to physiotherapy.
- Trial name
- NCT04269291
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cardiff and Vale University Health Board
Chronic Ankle Instability, Ankle Sprain
Impact of Chronic Ankle Instability on Jumping and Agility in Athletes
This study investigated how chronic ankle instability (CAI) affects functional performance in athletes compared with healthy controls.
- Conditions
- Chronic Ankle Instability, Ankle Sprain, Functional Performance Deficit, Athletic Performance
- Trial name
- NCT07171398
- Testing
- Functional Performance Testing Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Obesity, Childhood, Obesity, Adolescent
Reading Ability in Childhood Obesity
There is some evidence about the negative impact of overweight and obesity on reading ability, with negative consequences on quality of life and school success.
- Trial name
- Lettura_evOB (NCT06295406)
- Testing
- Neuropsychological assessment
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Parkinson's Disease
Executive, Activities of Daily Living, and Cholinergic Functions in Parkinson's Disease
This research study will evaluate functions of memory, thinking, behavior, and daily life activities and how these relate to the measurement of certain chemicals (acetylcholine and dopamine) in the brain using an imaging…
- Trial name
- NCT00737217
- Testing
- Behavioral assessment/questionnaire
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Desire to Exercise, Exercise Training
Guayusa Extract on Exercise Training
Guayusa extract is a caffeinated Amazonian 'super-leaf' belonging to the holly species that contains a very unique blend of polyphenol antioxidants and caffeine (~20% caffeine, 30% chlorogenic acids, 5% catechins).
- Conditions
- Desire to Exercise, Exercise Training, Physical Exertion
- Trial name
- NCT05820399
- Testing
- Organic Guayusa Extract
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Nathaniel Jenkins
Edentulism, Edentulism Complete
Masticatory Efficiency, Bite Force, and Patient-Reported Outcomes in Patients Rehabilitated With Complete and Partial Dentures Supported by Teeth, Mini-Implants, or Conventional Implants
This study aims to evaluate masticatory efficiency, bite force, and patient-reported outcomes in edentulous and partially edentulous patients rehabilitated with different removable prosthodontic treatment modalities.
- Conditions
- Edentulism, Edentulism Complete, Partial Edentulism, Complete Dentures
- Trial name
- IMPROSTREHAB (NCT07639112)
- Where
- 2 sites in Croatia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Body Mass Index, Body Mass Index 25 or Greater
Activities of Daily Living and Upper Extremity Exercise Capacity of Individuals with High Body Mass Index
Individuals with high and normal body mass index will be included in this study.
- Conditions
- Body Mass Index, Body Mass Index 25 or Greater, Body Mass Index, Normal
- Trial name
- NCT06745310
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Obesity, Cognitive Ability, General
Physical Activity and Intermittent Exercise Training for Cardiovascular and Cognitive Gain in Obese Women
One hundred participants from a combination of (a) local advertisements and/or (b) those whose details are held on a research database (of previous volunteers indicating willingness to be contacted about future studies) will be…
- Conditions
- Obesity, Cognitive Ability, General, Cardiovascular Disease
- Trial name
- NCT02853279
- Testing
- Interval exercise training, Continuous exercise training (CON)
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Dry Eye Syndromes
Impairment of Reading Ability in Dry Eye Patients
To assess the reading function impairment in patients with dry eye and to assess the effects of reading on the ocular surface.
- Trial name
- NCT01826812
- Testing
- 30 minutes sustained reading, Dry eye exam
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cervical Myelopathy
Proprioceptive Deficits in Degenerative Cervical Myelopathy
Proprioceptive deficits in degenerative cervical myelopathy (DCM) is a progressive neurological deficits in somatosensory and motor function which affects the body balance and motor control.
- Trial name
- NCT05183971
- Testing
- Proprioceptive Functional Analysis System
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Hemodialysis Complication
The Effect of Patient Education Based on Nursing Model on Life Activities and Self-Care of Hemodialysis Patients
Chronic Renal Failure (CRF); The result of a decrease in the glomerular filtration value is defined as a chronic and progressive deterioration in the fluid-solute balance of the kidney and metabolic-endocrine functions.
- Trial name
- NCT04797234
- Testing
- Control, Experiment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University