Clinical trials: Functional Ability
Unilateral Primary Osteoarthritis of Hip
Comparing the Clinical Effects of Posterior Approach Versus Lateral Approach in Osteoarthritis Patients With a THA
The aim of this study is to investigate the clinical outcome of the two different, but widely used, surgical approaches (Posterior approach and Lateral approach) of primary total hip arthroplasty in patients diagnosed with…
- Trial name
- COMPALA (NCT01616667)
- Testing
- Total hip arthroplasty
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
DUAL TASK, DEGLUTİTİON
Cognitive - Motor Dual Task and Swallowing
Swallow and dual-task are a current issue and there are few studies on this subject. These studies have shown that as a result of dual-task interaction, swallowing is affected by attention and cognitive capacity, and dual-task…
- Conditions
- DUAL TASK, DEGLUTİTİON, COGNİTİVE FUNCTİON, ACTİVİTİES OF DAİLY LİVİNG
- Trial name
- NCT05452135
- Testing
- Observation of visual, audotory and motor reaction time
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Atılım University
Electric Impedance, Healthy Volunteers
An Investigation Into an Objective Measure of Muscle Quality, Function and Ability
The assessment of muscular function, quality and ability is of high importance in a diverse range of clinical disciplines from anaesthetics to physiotherapy.
- Trial name
- NCT04269291
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cardiff and Vale University Health Board
Sleep Disordered Breathing, Able Bodied
Central Apnea in Heart Failure: Physiological Mechanisms to Inform Treatment
Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure therapy given the modest efficiency of positive…
- Trial name
- CSA-HF (NCT07210606)
- Testing
- Trazodone + positive airway pressure (PAP) therapy, Oxygen + positive airway pressure (PAP) therapy
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Brain Health, Brain Function
Effect of Fish Oil on Athlete's Executive Function
The goal of this study is to determine the impact of long chain omega-3 PUFA (Polyunsaturated fatty acids) supplementation on executive function in collegiate athletes in a randomized, double-blind, placebo-controlled trial
- Conditions
- Brain Health, Brain Function, Brain Development
- Trial name
- NCT04570995
- Testing
- Fish Oil, Safflower Oil
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Visual Function
Comprehensive Evaluation of Visual Function
The purpose of this study is to assess the level of visual functioning in patients with various eye conditions while wearing different types of eyeglasses.
- Trial name
- NCT00894192
- Testing
- Izon Wavefront-guided lenses, Conventional lenses
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Chicago Lighthouse
Gastro Esophageal Reflux Disorder
GERD and Anti-Reflux Therapy Between Able-bodied and SCI Individuals
Respiratory dysfunction, esophageal dysmotility, and a gastroesophageal reflux disease (GERD) have been demonstrated to be highly prevalent in persons with SCI.
- Trial name
- NCT02584751
- Testing
- Omeprazole, 24 Hour pH Monitor, Pulmonary Function Examination
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Distal Radius Fracture
Impact of Early ADL Participation on Outcomes Post DRF
This study is a randomized controlled trial (RCT). This RCT which will study the effect of performing daily activities early after a distal radius fracture being treated conservatively in a cast. This study will have two groups.
- Trial name
- NCT05650996
- Testing
- ADL/Cast Care instruction, Cast Care Instruction
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- George Washington University
Mild Cognitive Impairment, Mild Dementia
Validation of the German Version of the Amsterdam Instrumental Activities of Daily Living Questionnaire®
Pretest and validation of the German version of the Amsterdam instrumental activities of daily living questionaire short in elderly people with normal cognition, mild cognitive impairment (MCI) or mild dementia in the German…
- Trial name
- NCT04012398
- Testing
- Amsterdam IADL Questionnaire short, German version
- Where
- Switzerland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
Edentulism, Edentulism Complete
Masticatory Efficiency, Bite Force, and Patient-Reported Outcomes in Patients Rehabilitated With Complete and Partial Dentures Supported by Teeth, Mini-Implants, or Conventional Implants
This study aims to evaluate masticatory efficiency, bite force, and patient-reported outcomes in edentulous and partially edentulous patients rehabilitated with different removable prosthodontic treatment modalities.
- Conditions
- Edentulism, Edentulism Complete, Partial Edentulism, Complete Dentures
- Trial name
- IMPROSTREHAB (NCT07639112)
- Where
- 2 sites in Croatia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Heat Stress, Physiological Stress
Suitability of the 26 °C Indoor Temperature Upper Limit for Older Adults: Impacts of Clothing and Daily Activity
While an upper limit of 26°C has been shown to be protective for heat-vulnerable older occupants (DOI: 10.1289/EHP11651), this recommendation did not consider the added heat burden associated with increases in internal heat…
- Trial name
- NCT07189507
- Testing
- Simulated indoor temperature upper limit
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Performance Enhancement
CAF & Firefighters Performance
The aim of the study being to investigate chewing caffeine-containing gum could effectively improve firefighters' balance under conditions of brain fatigue.
- Trial name
- CAF & FFT (NCT07570030)
- Testing
- Caffeine (300 mg)
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Chih-Hui Chiu
Chemokine Receptor 2 (CXCR2) Antagonist
AZD5069 Neutrophil Function Study
Study in healthy volunteer to see effect of AZD5069 and placebo on neutrophil number and function (phagocytosis and oxidative burst) in the circulation, following a burst of strenuous exercise and following subcutaneous injection…
- Trial name
- NCT01480739
- Testing
- 100 mg (50 mg x 2) AZD5069
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Alzheimer's Disease, Mild Cognitive Impairment
System-IGF-1 Pathway and Alzheimer's Disease
The aim is to assess the relationship between levels of IGF-I system components and cognitive status in patients with Alzheimer's disease (AD), in elderly subjects with normal cognitive function, and in patients with mild…
- Conditions
- Alzheimer's Disease, Mild Cognitive Impairment, Cognitive Function 1, Social, Control With Normal Activities of Daily Living
- Trial name
- SIGAL (NCT00647478)
- Where
- France
- Volunteers
- 693 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Multitasking Behavior and Neural Representations Associated With Multitasking Ability, Healthy Volunteers
Cognitive Control & the Functional Organization of the Frontal Cortex
The goal of this basic experimental clinical trial is to understand the effect of multitasking practice on the structure of neural representations of tasks in the human lateral prefrontal cortex and control brain regions.
- Conditions
- Multitasking Behavior and Neural Representations Associated With Multitasking Ability, Healthy Volunteers, Executive Function
- Trial name
- NCT06436209
- Testing
- Multitask Practice Intervention (MPI), Single-task Practice Intervention (SPI)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brown University
Scoliosis Idiopathic, Vestibular Function Disorder
Evaluation of Vestibular Dysfunction or Visuospatial Perception in Individuals With Idiopathic Scoliosis
This study was planned to investigate whether there is a visual-spatial perception disorder in individuals with idiopathic scoliosis and also to reveal its dependent/independent relationship with vestibular dysfunction.
- Conditions
- Scoliosis Idiopathic, Vestibular Function Disorder, Visuospatial/Perceptual Abilities
- Trial name
- NCT05045014
- Testing
- Balance assessment, Unterberger test, Corsi Block Tapping (mobıl app)
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Inonu University
Stroke, Knowledge, Attitudes, Practice
Effects of an Educational Intervention on Rehabilitation Clinicians' Practices for Health-related Outcomes After Stroke
The overall aim of this pilot study is to evaluate the feasibility of a study protocol for a future stepped wedge cluster randomized clinical trial (c-RCT) that will investigate the effects of an innovative KT intervention on 1)…
- Conditions
- Stroke, Knowledge, Attitudes, Practice, Physical Disability, Motor Skills Disorders
- Trial name
- NCT03807115
- Testing
- Implementation of stroke mobility guidelines
- Where
- 6 sites in Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- McGill University
Sarcopenia, Osteoporosis, Osteopenia
Osteosarcopenia and Exercise
The purpose of this study is to assess the efficacy of combination of aerobic and resistive exercise on activities of daily living and risk of fall in osteosarcopenic patients
- Trial name
- NCT04526327
- Testing
- exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
COVID-19 Pandemic
Investigation of Physical and Emotional Status the Elderly Infected and Non-Infected With COVID-19
The aim of this observational study is to evaluate individuals in terms of balance, functional mobility, influences in activities of daily living, fear of COVID-19, moods, quality of life parameters in order to investigate the…
- Trial name
- NCT05905211
- Testing
- Observational Tests
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Tarsus University