Clinical trials: Functional Aging
HIV, Inflammation
Exercise for Healthy Aging: The Impact of HIV and Aging on Physical Function and the Somatopause
The primary objective of this proposal is to compare a moderate or high intensity exercise intervention to improve physical function in persons aging with Human Immunodeficiency Virus (HIV).
- Conditions
- HIV, Inflammation, Obesity, Aging, Biological
- Trial name
- NCT02404792
- Testing
- High-intensity cardiovascular and resistance exercise, Moderate-intensity cardiovascular and resistance exercise
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Aging
Fatty Acid Modulation of Brain Function in Older Adults
In this crossover study, the investigtors will administer two experimental diets in a random order for one week, and each experimental diet will be preceded by a one-week, low fat control diet for a total four-week study period.
- Trial name
- NCT06192407
- Testing
- High Oleic Acid Diet, High Palmitic Acid Diet
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Cardiovascular Disease, Diabetes
Taste Perception and Chronic Disease Risk
The purpose of the Taste Perception Study is to assess variations in the ability to taste and perceive sensations from various stimuli in younger (18-49 years) and older (50-85 years) volunteers.
- Conditions
- Cardiovascular Disease, Diabetes, Obesity, Metabolic Syndrome
- Trial name
- NCT01023906
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tufts University
Healthy
Diet and the Aging Brain
We investigate whether a change in diet could provide positive effects on general brain functions in healthy elderly people.
- Trial name
- NCT00463255
- Testing
- diet
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Healthy Aging, Vascular Dilation
Effects of a Supplement to Target Ageing Mechanisms on Vascular Function (STAMINA)
In the ageing society, extending the healthy lifespan is a major challenge and a healthy diet may play an import role in maintaining health throughout life.
- Trial name
- STAMINA (NCT06145087)
- Testing
- "NOVOS Core" supplement
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Healthy, Aging
Effects of Whole Body Vibration on Autonomic Function in Healthy Young and Elderly
Aging causes anatomical and physiological changes in the cardiovascular system and autonomic function with decline in its maximum function.
- Trial name
- NCT03180814
- Testing
- Whole Body Vibration
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Aging
Comparison of an Easy to Read Advance Directive Versus a Standard Advance Directive
The purpose of this study is to compare the acceptability, usefulness, self-efficacy and comprehension of an easy-to-read advance directive form versus a standard advance directive form written at a post graduate reading level.
- Trial name
- NCT00328055
- Testing
- AD-Easy (Advance Directive-Easy), AD-Standard (Advance Directive-Standard)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Aging
Metabolic and Functional Consequences of Aging in Health and Disease
Considerable heterogeneity in the aging population has been observed. The exceptional longevity of individuals reaching 100 years old, so-called centenarians may be an example of life-long healthy aging, or added years may be…
- Trial name
- NCT05240885
- Testing
- Stable tracer infusion in a postabsorptive state
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Aging, Fatigue
Description of Physical Activity Effect on Neuromuscular Fatigue of Older People
There is a decrease in cardiovascular and neuromuscular functions, which leads to reduced performance with advancing age. Physical activity provides health benefits, prevents and treats cardiovascular and neuromuscular disease.
- Trial name
- ACTIFS-AGE (NCT05413590)
- Testing
- Questionnaires completion, Isometric forces, Energy cost
- Where
- France
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Aging, Muscle Atrophy or Weakness
C-Protein in Fatigue and Aging
This study is investigating changes to the proteins in skeletal muscle that contribute to reduced muscle size and muscle function that occurs with aging.
- Conditions
- Aging, Muscle Atrophy or Weakness, Sarcopenia in Elderly, Sarcopenia
- Trial name
- NCT05926219
- Testing
- Fatiguing Exercise
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Cardiovascular Disease
Fitness and Daily Function in Adults
The purpose of this study is to examine the impact of aerobic fitness on the ability of able and disabled older adults to perform daily functional activities.
- Trial name
- NCT00018265
- Testing
- Task specific endurance training, Tai Chi
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Aging
Preliminary Testing of Cafe Move for Primary Prevention of Physical Frailty
This project explores a novel means of health promotion and prevention of age-related physical frailty, which is designed to overcome barriers to access and promote autonomy in managing physical health.
- Trial name
- NCT05720507
- Testing
- Cafe Move
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Montana
Aging, Cognitive Decline
Omega-3 Fatty Acids and Exercise on Mobility and Cognition in Older Women
The study will provide insight into how lifestyle-related interventions, specifically nutrition and exercise can impact the health of older women.
- Trial name
- MOBILE (NCT03228550)
- Testing
- Efamol Active 50+, Aerobic exercise
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Healthy
Japan Central Aortic Pressure Prospective Study
Purpose of the study 1. The predictive value of central aortic pressure and aortic pulse wave velocity (PWV) in a Japanese population is not known.
- Trial name
- J-CARP (NCT01243840)
- Where
- Japan
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Yoshio Matsui
Diastolic Dysfunction
Effect of Exercise on Heart Function in Healthy Elderly People
The purpose of this study is to determine the effect of aerobic interval training on left- and right ventricular diastolic- and systolic function on healthy, sedate people over 70 years.
- Trial name
- NCT00804518
- Testing
- Aerobic interval training
- Where
- Norway
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Age-related Cognitive Decline
Cognitive Engagement and Aging Mind
The purpose of this research is to examine whether and to what extent training of different types of cognitive engagement will improve performance on fluid cognitive abilities that typically decline with age.
- Trial name
- NCT05924490
- Testing
- Real-time strategy-based videogame training, Semantic Knowledge training
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Aging, Hospitalization
An ESD Model of Care for Older Adults Admitted to Hospital: a Protocol for a Descriptive Cohort Study
The MidWest multidisciplinary Community Intervention Teams (MD-CIT) comprise of specialist, healthcare teams that provide a rapid and integrated response to a patient with an acute episode of illness who requires enhanced…
- Conditions
- Aging, Hospitalization, Function
- Trial name
- NCT05731362
- Testing
- MDCIT Intervention
- Where
- Ireland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Limerick
Community-Dwelling Older Adults, Aging
The Efficacy of a Technology-Assisted Block Training Program on Cognitive Function, Hand Dexterity, and Grip Strength in Community-Dwelling Older Adults: A Mixed-Methods Research
Block-building activities represent a promising tool for enhancing cognitive and hand function in older adults. When integrated with technological support, they offer personalized training advantages; however, their comprehensive…
- Conditions
- Community-Dwelling Older Adults, Aging, Cognitive Decline, Hand Dexterity
- Trial name
- NCT07315724
- Testing
- Technology-Assisted Block Training Program
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Physiological Processes, Aging
Age-Related Changes in Stress Hormone Regulation
Studies investigating physiological processes involved in aging-related deficits in regulation of stress hormone systems.
- Trial name
- NCT00018369
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Aging
The Effects of 12 Weeks Pilates-inspired Exercise Training on Functional Performance in Older Women
The purpose of the present study was to investigate the effects of 12-week Pilates-inspired exercise on functional performance in community-dwelling older women.
- Trial name
- NCT02636296
- Testing
- Pilates, Control
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo