Clinical trials: Functional Capacity
Frail Elderly Syndrome
Effects of WBV Associated With IMT on Functionality
The pre-frail elderly are a population more vulnerable to diminished functionality and future disabilities. Thus, interventions focused on the prevention of sarcopenia are indicated to prevent dysfunction in this population.
- Trial name
- NCT03688932
- Testing
- WBV + IMT
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Health, Subjective, Gastrointestinal Dysfunction
Personal Lifestyle Engine (PLX) - Personal Lifestyle Medicine Center (PLMC)
It has been suggested that the best medicine should include four principles (4P) - Medicine should be personalized, predictive, preventative and participatory.
- Conditions
- Health, Subjective, Gastrointestinal Dysfunction, Cardiovascular Risk Factor, Autoimmune Diseases
- Trial name
- NCT04007939
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
MRI, MRI Image Enhancement
Optimizing Liver MRI Using Breath-Holding With and Without Oxygen
The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy…
- Trial name
- NCT07135401
- Testing
- Breath-hold conditions
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Multiple Sclerosis
EFFECTS OF AEROBIC AND RESISTANCE TRAINING ON IMMUNE FUNCTION IN MULTIPLE SCLEROSIS
Background: Multiple Sclerosis (MS) is a chronic immune-mediated, inflammatory, and neurodegenerative central nervous system disorder characterized by axonal damage.
- Trial name
- ABIF-MS (NCT07640100)
- Testing
- Aerobic and Progressive Resistance Exercise Program, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Seda Saka
Atrial Fibrillation
Effects of Exercise Training in Patients With Permanent Atrial Fibrillation
Atrial fibrillation (AF) is a common arrhythmia. The proposed patholophysiological mechanisms of AF include abnormal electrical conduction in atrium and sympathovagal imbalance with increased vagal tone.
- Trial name
- NCT01721863
- Testing
- Exercise training
- Where
- Taiwan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Overweight , Obesity
Immediate Effect of Whole-Body Vibration on Cardiovascular Response and Functional Capacity in Overweight/Obese Young Women
Obesity has become a major global public health issue, defined by an excessive accumulation of body fat that presents substantial health risks.
- Trial name
- NCT07263243
- Testing
- Whole-body vibration device
- Where
- Saudi Arabia
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oxidative Stress, Inflammation
Effects of Magnesium and Spinning Training on Echocardiographic, Inflammatory, and Aerobic Outcomes
Regular aerobic exercise may improve cardiorespiratory fitness while modulating systemic inflammation and oxidative stress. Spinning, as a structured indoor cycling modality, provides a practical aerobic exercise model with…
- Conditions
- Oxidative Stress, Inflammation, Physical Fitness, Echocardiography
- Trial name
- NCT07662954
- Testing
- Spinning Training, Magnesium Supplementation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Respiratory Function
Effect of a Respiratory Training Program on Woodwind and Brass Players
This project will study the effect of a respiratory training program on woodwind and brass players, using an inspiratory muscle training equipment.
- Trial name
- NCT06175286
- Testing
- POWERBreath Plus Medium Resistance training device
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Hypertension
Unilateral and Bilateral Resistance Training in Hypertension
Hypertension is associated with autonomic nervous system dysfunction, reduced muscle strength, and impaired functional capacity, all of which contribute to increased cardiovascular risk and decreased quality of life.
- Trial name
- NCT07751445
- Testing
- Unilateral Resistance Training, Bilateral Resistance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Myocardial Ischemia, Heart Diseases
Cardiac Rehabilitation: Optimisation of the Functional Capacity of Patients Hospitalized With Cardiac Disease
The World Health Organization [WHO] (2021) states that Cardiovascular Diseases [CVD] are the leading cause of death in the world, and in 2019 around 17.9 million deaths were caused by CVD and the national picture is no different.
- Trial name
- NCT06546878
- Testing
- Cardiac Rehabilitation (Phase I) - nurse intervention
- Where
- Portugal
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- José Manuel Afonso Moreira
Multiple Sclerosis
Cognitive Functions in Patients With Multiple Sclerosis
Approximately 65% of multiple sclerosis (MS) patients appear to have problems in their cognitive function. Long-term memory is one of the most frequently affected functions in MS patients.
- Trial name
- NCT03594357
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Gazi University
Frailty Syndrome, Sarcopenia
Design and Validation of FEXO: A Playful Exercise Program for Institutionalized Frail Older Adults
This multicenter randomized controlled trial aims to evaluate the effectiveness of a playful multicomponent exercise intervention (FEXO - Fun Exercise for Older Adults) on intrinsic capacity, frailty, and functional health in…
- Trial name
- FEXO-FRAIL (NCT07133581)
- Testing
- FEXO (Fun Exercise for Older Adults)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Coronary Artery Disease, Coronary Heart Disease
Impact of Cardiac Rehabilitation on Patient Outcomes
Objective: This study aimed to retrospectively evaluate the impact of cardiac rehabilitation (CR) on functional capacity, depressive symptoms, health-related quality of life, and sleep quality in patients with heart disease.
- Trial name
- NCT07468955
- Testing
- Exercise Based Cardiac Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Heart Failure
Effects of Inspiratory Muscle Training on Functional Capacity in Patients With Heart Failure.
Heart failure is a complex clinical syndrome manifesting as inability to supply adequate blood flow throughout the body due to any structural or functional cardiac abnormality.
- Trial name
- NCT05005702
- Testing
- Inspiratory Muscle training
- Where
- Pakistan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Early Mobilization, Physiotherapy
Rehabilitation of Patients From the ICU to the Post-hospital Phase
Introduction: Advances in knowledge have contributed to the increase in the number of patients who survive prolonged hospitalization in an Intensive Care Unit (ICU), and, among them, critically ill patients who develop acute…
- Conditions
- Early Mobilization, Physiotherapy, Rehabilitation
- Trial name
- NCT06405529
- Testing
- Early and intensive mobilization protocol at the ICU and Rehabilitation post-hospital discharge
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Veteran Aged 65 and Older
Promoting Cognitive Resilience and Reducing Frailty in Older Veterans With Bright Light Therapy
Frailty is a multifactorial syndrome characterized by vulnerability to stressors that is intricately linked to cognitive impairment and mortality risk.
- Trial name
- Brite-VET (NCT05631236)
- Testing
- Bright Light Therapy (AYO Glasses)
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cancer, Cancer-Related Syndrome
Effects of a Multimodal Physical Exercise and Functional Rehabilitation Program on Fatigue, Pain, Functional Capacity and Quality of Life in Cancer Patients With Tumor Asthenia.
Tumor asthenia is the most common symptom associated with cancer and its treatment. Although the estimated prevalence varies between 60-90%, and it is considered the longest-lasting symptom in cancer patients, having the greatest…
- Conditions
- Cancer, Cancer-Related Syndrome, Fatigue
- Trial name
- NCT04761289
- Testing
- Multimodal Exercise and Functional Rehabilitation Program
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Coronary Artery Disease
Fear of Activity and Functional Capacity in Patients With Coronary Artery Disease
To identify whether coronary artery disease (CAD) patients have fear of activity, and to assess the relationship between fear of activity and exercise capacity in CAD patients.
- Trial name
- NCT04335760
- Testing
- Modified Bruce protocol on treadmill
- Where
- Turkey (Türkiye)
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Tuğba Atan
Chronic Obstructive Pulmonary Disease
Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPD
Chronic obstructive pulmonary disease (COPD) is a condition characterized by airway obstruction. Patients with COPD experience significant shortness of breath on exertion.
- Trial name
- NCT05061368
- Testing
- Sildenafil Citrate
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cardiovascular Disease
Cardiovascular Prophylaxis for Postmenopausal Women
The purpose of this study was to examine the effect of 6 months moderate intensity exercise training completed three times per week upon traditional and emerging cardiovascular disease risk factors in postmenopausal women both…
- Trial name
- NCT01219725
- Testing
- Exercise training
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Leeds