Clinical trials: Functional Chest Pain
Lumbosacral Radiculopathy
Effect of Thoracic Mobilization on Lumbar Radiculopathy
The purpose of the study will be to: To investigate the effect of thoracic mobilization on back and leg pain in patients with lumbosacral radiculopathy.
- Trial name
- NCT06167044
- Testing
- thoracic mobilization
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Erectile Disfunction, Coronary Artery Disease (CAD)
"Erectile Function After PCI in MI and Non-MI Patients"
The goal of this observational study is to assess changes in patients' erectile function after percutaneous coronary intervention (PCI) using a standard IIEF (International Index of Erectile Function) questionnaire at 1, 3, and 6…
- Conditions
- Erectile Disfunction, Coronary Artery Disease (CAD), Diabete Mellitus, Anxiety
- Trial name
- ERECT-PCI (NCT07444697)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Myocardial Infarction, Angina, Unstable
Using Magnetic Resonance Imaging to Evaluate Heart Vessel Function After Angioplasty or Stent Placement Procedures
Coronary artery disease (CAD) is caused by a narrowing of the blood vessels that supply blood and oxygen to the heart. Balloon angioplasty and stent placement are two treatment options for people with reduced heart function…
- Conditions
- Myocardial Infarction, Angina, Unstable, Cardiomyopathy, Hypertrophic
- Trial name
- NCT00692991
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Johns Hopkins University
Aging, Mild Cognitive Impairment
A Study of Characterizing Cognitive Decline and Functional Cardiac Senescence in Healthy Korean Volunteers
Although aging process appears to be generally characterized, investigators have been paid much attention to the specific target molecules, which leads to discover the clinical markers of the senescence.
- Conditions
- Aging, Mild Cognitive Impairment, Angina Pectoris
- Trial name
- NCT01590706
- Where
- South Korea
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Korea Institute of Oriental Medicine
Rib Fractures
Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture Ribs
In our study, we assess the diaphragmatic function, pain quality and anti-inflammatory properties between low dose infusion of dexmedetomidine normal saline in patients with multiple fracture ribs on conservative treatment.
- Trial name
- NCT04928300
- Testing
- Dexmedetomidine, 0.9% saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Back Pain
Comparative Effects of Soft Tissue Mobilization and Pressure Therapy With and Without Dynamic Cupping on on Pain and Disability in Patients With Thoracic Back Pain.
This study aims to compare the sequential effects of Instrument-Assisted Soft Tissue Mobilization (IASTM) and Transverse Oscillatory Pressure (TOP), with and without Directional Dynamic Cupping, in patients with thoracic back…
- Trial name
- NCT07892066
- Testing
- Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP), Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP) and Directional dynamic cupping
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- University of Management and Technology Lahore
Pain, Inadequate or Impaired Respiratory Function
Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder Pain
The purpose of the study is to examine if the hyposthesis of the preventive analgestic characteristic of diclofenac given preoperatively has any effect on postoperative thoracic wall and shoulder pain sensation.
- Trial name
- NCT02445599
- Testing
- Diclofenac, Midazolam, Atropine
- Where
- Hungary
- Volunteers
- 3 people
- Sponsor
- University of Debrecen
Cardiovascular Diseases
NITRATE-OCT-CIN (Sub-Study of NITRATE-OCT)
The NITRATE-OCT:- Contrast Nephropathy Sub-study is a proof-of concept single center, randomized, clinical trial designed to ascertain whether a dietary NO3- approach might prove useful adjunctive therapy improving renal function…
- Trial name
- NIT-OCT-CIN (NCT05544981)
- Testing
- Beetroot Juice
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Queen Mary University of London
Back Pain
Effects of Cervicothoracic Mobility Program on Low Back Pain
The study will be a randomized control trial to determine the effects of the cervicothoracic mobility program on pain, range of motion, and function in patients with chronic back pain.
- Trial name
- NCT05347251
- Testing
- Cervicothoracic mobility program, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras
Chest Pain, CAD
Comparing a Diagnostic and Treatment Strategy of Upfront CTCA With SOC in Patients With Chest Pain and Suspected CAD
Rationale: Patients with chest pain usually undergo multiple diagnostic examinations to demonstrate or rule out atherosclerotic coronary artery disease (CAD).
- Trial name
- CLEAR-CAD (NCT05344612)
- Testing
- CT Coronary Angiography
- Where
- Netherlands
- Volunteers
- 6,444 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Refractory Angina, Raised Lipoprotein(a)>50mg/dL or >500mg/L
Lipoprotein Apheresis in Refractory Angina Study
The goal of this study is to determine the impact of apheresis on clinical parameters and symptoms of patients with refractory angina and raised Lp(a).
- Trial name
- NCT01796912
- Testing
- Lipoprotein Apheresis
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Imperial College London
Chest Tube Removal, Heart; Surgery, Heart, Functional Disturbance as Result
Foot Reflexology to Reduce Pain and Anxiety Before Chest Tube Removal
In open heart surgeries, patients experience severe pain due to tissue trauma, damage to intercostal nerves, and muscle spasm due to pulling tubes from the mediastinal space and between the pleural leaves pull during chet tube…
- Conditions
- Chest Tube Removal, Heart; Surgery, Heart, Functional Disturbance as Result, Pain, Anxiety
- Trial name
- NCT05032469
- Testing
- Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Baskent University
Fracture Rib
Rhomboid Intercostal and Sub-Serratus Block for Improving Pulmonary Function and Pain in Patients With Fracture Ribs
Rib fractures are seen in more than 50% of patient spresenting with blunt chest trauma and are associated with significant morbidity, long-term disability and mortality .
- Trial name
- NCT05898958
- Testing
- thoracic paravertebral block, rhomboid intercostal and subserratus block
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Cardiovascular Diseases
Investigating the Effects of Dietary Nitrate on Vascular Function, Platelet Reactivity and Restenosis in Stable Angina
The mainstay treatment for reducing the symptoms of angina and long-term risk of heart attacks in patients with heart disease is stent implantation in the diseased coronary artery.
- Trial name
- NITRATE-OCT (NCT02529189)
- Testing
- Beetroot Juice
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Queen Mary University of London
Acute Coronary Syndromes
Study to Learn When Platelets Return to Normal After One Loading Dose of Anti-platelet Drugs in Patients With Symptoms of Acute Coronary Syndromes
To investigate how platelets recover to normal function in subjects who have symptoms of a heart attack or unstable angina and who get a loading dose of prasugrel or clopidogrel for planned coronary angiography.
- Trial name
- NCT01107899
- Testing
- clopidogrel, prasugrel
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- Eli Lilly and Company
Myocardial Infarction, Death
Association of Endothelial Function and Clinical Outcomes in Subjects Admitted to Chest Pain Unit
It is recognized that endothelial dysfunction is a major factor contributing to the atherogenic process. Abnormal function of the endothelium is detectable prior to obvious intimal lesions in patients with risk factors for…
- Conditions
- Myocardial Infarction, Death, Cerebrovascular Accident, Congestive Heart Failure
- Trial name
- NCT01618123
- Where
- 2 sites in United States, Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Acute Pain, Chronic Pain
The Role of Cognitive Function and Electroencephalography on Acute and Chronic Pain After Surgery
The project will apply the methods of clinical observation experiment, (1) to collect the cognitive function data preoperatively and early postoperatively, as well as the pain score data at multiple time points pre- and…
- Conditions
- Acute Pain, Chronic Pain, Thoracic Surgery, Electroencephalography
- Trial name
- NCT03761576
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yi Feng, MD
Angina, Unstable, Myocardial Infarction
Heart Function and Exercise Capacity in Patients With Hypertrophic Cardiomyopathy
This study will examine the relationship between certain measures of heart function and exercise capacity in patients with hypertrophic cardiomyopathy (HCM).
- Conditions
- Angina, Unstable, Myocardial Infarction, Ischemic Heart Disease
- Trial name
- NCT00354328
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Percutaneous Coronary Intervention, Myocardial Ischemia
Analysis of Myocardial Layer Specific Systolic and Diastolic Function During and After PCI
Investigators will analyzed systolic and diastolic function during and after ischemia induced by percutaneous coronary intervention.Also will be analyzed a local work index during acute ischemia induced by percutaneous coronary…
- Conditions
- Percutaneous Coronary Intervention, Myocardial Ischemia, Anginal Pain
- Trial name
- PCI-Strain (NCT02004483)
- Testing
- Percutaneous Coronary Intervention
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- RWTH Aachen University