Clinical trials: Functional Cognitive Disorder
Delirium, Impaired Cognition
Simultaneous Recumbent Cycling and Cognitive Training
Intensive care units (ICU) provide life-saving care for nearly five million people annually. Up to 80% of patients receiving care in an ICU experience at least one episode of delirium.
- Trial name
- NCT04556227
- Testing
- Simultaneous Cycle/Cognitive Training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Missouri, Kansas City
Type 2 Diabetes Mellitus
Enhancement of Cerebral Vasoreactivity and Cognition by Intranasal Insulin in Type 2 Diabetes
Our goal is to determine the acute effects of intranasal insulin on regional perfusion and cognition of older adults. We propose a pilot study to examine the effect of a single dose of intranasal insulin on regional…
- Trial name
- NCT01206322
- Testing
- Intranasal insulin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Mild Cognitive Impairment
Efficiency of CogniPlat on Cognitive Functions in Older Adults
Mild cognitive impairment is a common intermediate stage between normal aging and dementia, affecting memory and other cognitive domains in older adults.
- Trial name
- NCT07130591
- Testing
- Cogniplat game platform, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Stroke
Effect of Sensorimotor Training Versus Dual-task Training
The aim of this study is to determine the comparative effects of sensorimotor training and dual-task training on propriocetion, balance, functional mobility and fall risk in stroke patients.
- Trial name
- NCT07628374
- Testing
- Sensorimotor Training, Dual-Task Training, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Post-acute Sequelae of SARS-CoV-2 Infection
Cognitive-Sensorimotor Function in Long-COVID
Growing evidence indicates that many people who have chronic post-acute sequelae of SARS-CoV-2 infection (PASC) will experience ongoing neurological and musculoskeletal impairment that can affect gait and balance.
- Trial name
- NCT06850350
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anxiety Disorders, Depression
Mindfulness-based Stress Reduction and Cognitive Function in Stress and Aging
The investigators are developing and then testing whether Mindfulness-Based Stress Reduction, a group-based instruction for increasing mindfulness, reduces anxiety and depressive symptoms and improves cognitive functioning in…
- Trial name
- NCT01693874
- Testing
- MBSR, control (health education)
- Where
- 2 sites in United States
- Volunteers
- 103 people
- Sponsor
- Washington University School of Medicine
Mental Health (Depression), Mental Health and General Well-being
Thrive at Home: A Virtual Reality Social Intervention for Older Adults
The goal of this clinical trial is to evaluate whether a virtual reality (VR) based social platform can improve mental health and social connection for older adults who receive in-home care.
- Conditions
- Mental Health (Depression), Mental Health and General Well-being, Loneliness, Well Being
- Trial name
- Thrive at Home (NCT07835568)
- Testing
- Full Virtual Reality Social Intervention, Abbreviated Virtual Reality Social Intervention
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Alzheimer's Disease, MCI Due to AD
Language, Speech and Motor Function in MCI Due to AD and Alzheimer's Disease
The goal of this observational cross-sectional study is to explore the characteristics of language, speech, and motor function in persons with Mild Cognitive Impairment due to Alzheimer's disease ("MCI due to AD") and persons…
- Conditions
- Alzheimer's Disease, MCI Due to AD, Dementia Alzheimers
- Trial name
- NCT06508268
- Testing
- GAITRite walkway system OR 4-meter walking speed test, Jamar hand dynamometer, Picture description task
- Where
- Netherlands
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hanze University of Applied Sciences Groningen
Obstructive Sleep Apnea, Acute Coronary Syndrome
Attentional Capacity and Working Memory in Coronary Artery Disease Patients: Impact of the Presence of a Sleep Apnea Syndrome and Chronic Effects of Treatment With CPAP
The presence of Obstructive Sleep Apnea Syndrome (OSAS) has a high frequency in patients victims of a coronary artery disease (CAD) (myocardial infarction, revascularization).
- Trial name
- CAPCORSAS (NCT02533050)
- Testing
- CPAP treatment
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Schizophrenia
Efficacy of Cognitive Remediation in Patients With Schizophrenia or Schizoaffective Disorder Stabilized on Lurasidone
The investigators hypothesize that cognitive remediation will be superior to the active control group on the change from baseline to study end point of cognitive remediation phase on both co-primary outcome measures (standardized…
- Trial name
- NCT01173874
- Testing
- Cognitive Remediation
- Where
- 16 sites in United States
- Volunteers
- 120 people
- Sponsor
- New York State Psychiatric Institute
Psychotic Disorders
Cognitive Remediation and Supported Education in Psychotic Disorders
This trial aims to assess the added value of cognitive remediation therapy to supported education intervention in young adults with a psychotic disorder.
- Trial name
- REUSSIR (NCT04040829)
- Testing
- Cognitive remediation therapy (CR), Supported education (SE), Treatment as usual (TAU)
- Where
- 3 sites in Canada
- Volunteers
- 9 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire en Santé Mentale de Québec
Mild Cognitive Impairment
Effects of Cognitive-motor Training on Cognition, Depression and Daily Functioning in Patients With Mild Cognitive Impairment (MCI)
This randomized controlled trial evaluated the effectiveness of an immersive virtual reality (IVR) application (focused on a daily activity) to train cognitive functions and its impact on depression and the ability to perform…
- Trial name
- NCT06313931
- Testing
- cognitive training via immersive virtual reality, cognitive training via paper and pencil, motor stimulation
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Universidad de Zaragoza
Schizophrenia
Effects of Weekly Dosing of D-cycloserine on Cognitive Function in Individuals With Schizophrenia
The study aims to assess the effects of single dose and repeated weekly dosing of 50mg d-cycloserine versus placebo on cognitive and memory functioning in schizophrenia patients.
- Trial name
- NCT00455702
- Testing
- d-cycloserine
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Massachusetts General Hospital
Stroke
Smart Technologies in Early Post-Stroke Rehabilitation
The goal of this interventional study is to evaluate the impact of applying different smart technologies during early rehabilitation after stroke.
- Trial name
- SMART-Stroke (NCT07171073)
- Testing
- RecoveriX, Gloreha Aria, E-Link System
- Where
- 2 sites in Lithuania
- Volunteers
- 200 people
- Sponsor
- Erika Endzelyte
Bipolar I Disorder, Cognitive Impairment
Assessing the Role of Cariprazine in Improving Cognition in Euthymic Bipolar Patients
Some patients with bipolar disorder show broad cognitive impairments (e.g. difficulty with concentration, problem solving, memory etc.) that persist during euthymia (no symptoms of depression or mania) despite remission of mood…
- Trial name
- CARPZ-01 (NCT04771299)
- Testing
- Cariprazine
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Lakshmi N Yatham
ADHD - Attention Deficit Disorder With Hyperactivity, Autism Spectrum Disorder
Virtual Reality-assisted Cognitive Rehabilitation in Autistic Youth With ADHD
This study aims to evaluate the effectiveness of a virtual reality-based intervention using the Virtual Reality Rehabilitation System (VRRS) to improve executive functions in autistic and ADHD youth aged 8 to 18 years.
- Trial name
- NCT07426302
- Testing
- VRRS Cognitive Training, Treatment as Usual (TAU)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
PARKINSON DISEASE (Disorder)
Effect of Hand Rehabilitation on Cognitive Function in Patients With PD
Evidence suggests the association between fine motor skills of the hand and cognitive function, as well as the positive effects of hand rehabilitation on hand function and the effectiveness of cognitive rehabilitation on…
- Trial name
- NCT07702929
- Testing
- Hand Sensorimotor Rehabilitation, Cognitive Remediation
- Where
- Iran
- Volunteers
- 48 people
- Sponsor
- Isfahan University of Medical Sciences
Migraine Disorders
Cognitive Function and Autonomic Regulation in Patients With Migraine
Individuals with migraine have impaired cognitive function and worse autonomic function compared to individuals without migraine.
- Trial name
- NCT04272229
- Testing
- Cognition, Sympathetic Nervous System, Concentratio and Attention
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fortaleza University
Coronary Syndrome
Determinants of Cognitive Impairment After Acute Coronary Syndrome
The general purpose of the present pathophysiological study is to investigate the relation between cognitive impairment observed after an acute coronary syndrome and the presence of cerebral anatomo-functional abnormalities.
- Trial name
- COSCA (NCT00982176)
- Testing
- Brain MRI and cerebral perfusion scintigraphy
- Where
- 2 sites in France
- Volunteers
- 49 people
- Sponsor
- University Hospital, Bordeaux
Brain Injury, Chronic
Treatment of Traumatic Brain Injury With Hyperbaric Oxygen Therapy
The purpose of this study is to determine if hyperbaric oxygen therapy (HBOT) improves the cognitive function of OIF/OEF individuals who have chronic mild to moderate traumatic brain injury (TBI).
- Trial name
- NCT00810615
- Testing
- Hyperbaric oxygen @ 2.4 ATA
- Volunteers
- 50 people
- Sponsor
- San Antonio Military Medical Center
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