Clinical trials: Functional Cognitive Disorder
Gambling
Effectiveness of Exergames on Cognitive, Social Functionamong Chronic Schizophrenia
An experimental study with random assignment will be adopted. The participants from 2 hospitals will be assigned to two groups: experimental group (n=77), and control group (n=77).
- Trial name
- exergames (NCT05933356)
- Testing
- playing exergames, scheduled activities
- Where
- Taiwan
- Volunteers
- 154 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
End Stage Renal Disease
Alterations in Cognitive Function and Cerebral Blood Flow After Conversion From Calcineurin Inhibitors (CNIs) to Everolimus
The purpose of this study is to learn if changing from Tacrolimus to Everolimus will improve cognitive function by having less effect on brain blood flow.
- Trial name
- NCT03413722
- Testing
- Tacrolimus, Everolimus
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Kansas Medical Center
Neurologically Unimpaired Elderly Participants, Subjective Cognitive Decline (SCD)
Italian Adaptation and Validation of Functional and Behavioural Scales for Subjective Cognitive Decline, Mild Cognitive Impairment and Mild Dementia.
The first aim of the observational study is the translation, cross-cultural adaptation and validation of functional and behavioral scales used in the diagnosis of neurodegenerative diseases, for which a formal version in Italian…
- Conditions
- Neurologically Unimpaired Elderly Participants, Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI), Major Neurocognitive Disorder
- Trial name
- ITA-VALI-DEM (NCT06701630)
- Where
- Italy
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Casa di Cura IGEA
Alzheimer's Disease
Deep Cervical Lymphovenous Anastomosis for Moderate Alzheimer's Disease
This is a multicenter, prospective, open-label, endpoint-blinded randomized controlled clinical study. We aim to evaluate the safety and efficacy of deep cervical lymphovenous anastomosis (LVA) combined with routine treatment for…
- Trial name
- LYMVA-AD (NCT07658430)
- Testing
- Deep cervical lymphovenous anastomosis (LVA), Routine Treatment
- Where
- China
- Volunteers
- 296 people
- Sponsor
- Southwest Hospital, China
Breast Cancer
Study of the Effects of Chemotherapy on Memory and Other Mental Functions in Women With Breast Cancer
Many breast cancer patients treated with chemotherapy complain of problems with concentration and memory. This has been referred to as chemo fog.
- Trial name
- NCT00260975
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Alcohol Dependence, Bipolar Disorder
Treatment of Alcohol Dependence and Comorbid Bipolar Disorder
The study will determine if individuals with co-occurring bipolar disorder and alcohol dependence report reduced alcohol consumption, improvement in mood symptoms, and cognitive performance if treated with lamotrigine plus their…
- Conditions
- Alcohol Dependence, Bipolar Disorder, Depression, Mania
- Trial name
- NCT01015586
- Testing
- Lamotrigine
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Medical University of South Carolina
Parkinson's Disease (PD)
The Effects of Ballet-Based Exercise Training on Respiratory Functions, Balance, Cognitive Functions, Peripheral Muscle Strength, Functional Capacity and Quality of Life in Patients With Parkinson's Disease
This study investigates the impact of an 8-week ballet-based dance therapy on people with Parkinson's disease. It aims to assess the effect of ballet on motor and non-motor symptoms, such as balance, cognitive function…
- Trial name
- NCT06986941
- Testing
- Ballet-Based Dance Therapy, Standard Care with Exercise Counseling
- Volunteers
- 24 people
- Sponsor
- Bezmialem Vakif University
Fibromyalgia
A Study To Assess Esreboxetine's Effect On Concentration, Memory, Decision Making And Problem Solving In Patients With Fibromyalgia.
The study is designed to assess if esreboxetine can improve the cognitive function of patients with fibromyalgia. Cognitive function is defined as the ability to concentrate, remember things and make decisions or problem solve.
- Trial name
- NCT00752505
- Testing
- Esreboxetine
- Where
- 7 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Pfizer
Parkinson, Cognitive Impairment
The Effect of Cognitive Functions on Upper Extremity Functionality in Parkinson's Patients
Parkinson's Disease (PD), first described by James Parkinson in 1817, is a progressive movement disorder that develops mainly as a result of the destruction of nigrostriatal dopaminergic neurons.
- Conditions
- Parkinson, Cognitive Impairment, Upper Extremity Problem, Functional Disturbance
- Trial name
- NCT05872646
- Testing
- clinical assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Cognitive Function and Mood, Cerebral Blood Flow
The Effects of Resveratrol Supplementation on Cognition, Cerebral Blood Flow, Microbiota and Systemic Inflammation.
Previous research shows that a diet high in fat has harmful effects on gut health. This increases the chance of developing obesity-related diseases (such as type 2 diabetes) and disrupts cognition and mood.
- Conditions
- Cognitive Function and Mood, Cerebral Blood Flow, Systemic Inflammation, Gut Microbiota
- Trial name
- NCT03448094
- Testing
- Resveratrol
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Psychotic Disorders
Short-term Working Memory and Executive Training
Cognitive remediation (CR) therapies refer to a number of recent developments to use behavioural strategies to improve neurocognitive abilities and improve everyday functioning in mental disorders such as schizophrenia, bipolar…
- Trial name
- STExFx (NCT02168166)
- Testing
- Executive Function Training
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Queen's University
Clinical High Risk for Psychosis
Targeted Cognitive Training in Clinical High Risk (CHR) for Psychosis
This project is a randomized-controlled trial to test the efficacy of computer-based targeted cognitive training (TCT) versus a placebo intervention of commercial computer games in adolescent/young adults at clinical high risk…
- Trial name
- NCT02404194
- Testing
- Targeted Cognitive Training, Computer Games
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Rush University Medical Center
Cognitive Function Assessment, Mild Cognitive Impairment
Prediction of Cognitive Test Performance Using AI-Based Analysis of Narrative Speech
This study aims to evaluate a new artificial intelligence (AI)-based method for measuring cognitive function using speech recordings.
- Conditions
- Cognitive Function Assessment, Mild Cognitive Impairment, Subjective Cognitive Decline
- Trial name
- NCT07511270
- Testing
- AI-Based Storytelling Speech Assessment
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Parkinson Disease, Gait
Computer-based Cognitive Training for Parkinson Disease
Parkinson's Disease (PD) is a neurodegenerative, progressive illness. It is a multi-system disease that influences not only the motor but also the cognitive and autonomic systems.
- Trial name
- NCT01121627
- Testing
- Computerized cognitive training
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Clalit Health Services
Cognitive Decline, Healthy
The Effects of Attentional Filter Training on Working Memory
The investigators are interested in how attentional filter training/ distractor inhibition training could influence cognitive functions like working memory, executive control, problem solving, decision making and attentional…
- Conditions
- Cognitive Decline, Healthy, Age-related Cognitive Decline
- Trial name
- DIIN (NCT03228446)
- Testing
- filter training, memory training, no training (control)
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- German Center for Neurodegenerative Diseases (DZNE)
Post-Concussion Syndrome, Concussion, Brain
Personalized Brain Stimulation to Treat Chronic Concussive Symptoms
The goal of this study is to investigate a new treatment for chronic symptoms after concussion or mild traumatic brain injury in people aged 18-65 years old.
- Conditions
- Post-Concussion Syndrome, Concussion, Brain, Mild Traumatic Brain Injury, Head Injury
- Trial name
- NCT06073886
- Testing
- Active cTBS, Imaginal exposure
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Los Angeles
Cognitive/Functional Effects, Metastatic Cancer
Sunitinib Malate After Stereotactic Radiosurgery in Treating Patients With Newly Diagnosed Brain Metastases
RATIONALE: Sunitinib malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Conditions
- Cognitive/Functional Effects, Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00910039
- Testing
- sunitinib malate, cognitive assessment
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- Case Comprehensive Cancer Center
Alzheimer Disease, Parkinson Disease
Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies
The role of disorders of socio-emotional processes in cerebral diseases such as Alzheimer's disease, frontal temporal dementia, Parkinson's disease, Huntington's disease, traumatic brain injury, stroke, focal lesions, has been…
- Conditions
- Alzheimer Disease, Parkinson Disease, Frontal Dementia, Huntington Disease
- Trial name
- GREFEXII (NCT03052712)
- Testing
- social cognition
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cognitive Impairment
Cognitive Sensorimotor Training With Whole Body Vibration for Cognitive Impairment
Aging is associated with cognitive decline, ranging from normal to mild cognitive impairment or dementia. This leads to physical and cognitive impairment, which are risk factors for loss of autonomy therefore physical and…
- Trial name
- NCT06927492
- Testing
- Cognitive Sensorimotor training along with whole body vibration, Cognitive Sensorimotor training
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
ICU Delirium
Modified Hospital Elder Life Program at Intensive Care Unit
Delirium, a form of acute brain dysfunction, occurs in up to 81% of patients receiving mechanical ventilation in the intensive care unit (ICU).
- Trial name
- mHelp@ICU (NCT06054828)
- Testing
- mHELP@ICU
- Where
- Taiwan
- Volunteers
- 266 people
- Sponsor
- National Taiwan University Hospital