Clinical trials: Functional Disabilities
Down Syndrome, Trisomy 21
Executive Function Play Opportunities for Children With Down Syndrome
The Executive Function Play Opportunities (EXPO) study is a sequential, multiple assignment, randomized trial (SMART) evaluating adaptive caregiver-mediated intervention pathways for improving executive function (EF) in children…
- Trial name
- EXPO (NCT07792382)
- Testing
- EXPO, EXPO Extended, EXPO Foundations
- Where
- 2 sites in United States, Italy
- Volunteers
- 150 people
- Sponsor
- Colorado State University
Down Syndrome
Hippotherapy Versus Balance Therapy on Funvtional Mobility in Down Syndrome
Down Syndrome is a genetic condition caused by having an extra copy of chromosome 21 and 47 chromosomes instead of 46. A complete or partial extra copy of chromosome 21 is responsible for the anomaly and related structural and…
- Trial name
- NCT06502652
- Testing
- hippotherapy, balance training
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Neurodevelopmental Disorders, Attention Deficit Hyperactivity Disorder
Videoconferencing-based Focused Acceptance and Commitment Therapy for Parents of SHCN Children
The purpose of the proposed non-randomized waitlist-controlled design study is to evaluate the feasibility, acceptability, and potential effectiveness of using a Videoconferencing-based Individual Focused Acceptance and…
- Conditions
- Neurodevelopmental Disorders, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Development Delay
- Trial name
- NCT05803252
- Testing
- Focused Acceptance and Commitment Therapy, Waitlist Control
- Where
- 5 sites in Hong Kong
- Volunteers
- 104 people
- Sponsor
- Chinese University of Hong Kong
Upper Crossed Syndrome
Comparative Effect of Janda's Approach and Mckenzie Exercises in Patients With Upper Cross Syndrome
This study was conducted compare the effect Janda's Approach and Mckenzie Excercises in patients with Upper Crossed Syndrome
- Trial name
- JAM-USC (NCT07841639)
- Testing
- McKenzie Treatment, Janda's Approach, Baseline Treatment
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Burns
Russian Current and Muscle Energy Techniques on Circumferential Upper Arm Burn
Burn injuries, particularly circumferential upper arm burns, present significant challenges in rehabilitation due to their impact on pain management, muscle strength, and overall functional abilities.
- Trial name
- NCT07174232
- Testing
- Russian current and muscle energy techniques, Russian Current
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- MTI University
Low Back Pain
Disease Perception and Recovery From Low Back Pain
The main purpose of the study is to investigate the importance of patients' beliefs regarding staying active despite low back pain, among patients referred from general practice to secondary care treatment in Denmark.
- Trial name
- NCT03058315
- Where
- Denmark
- Volunteers
- 828 people
- Sponsor
- Central Jutland Regional Hospital
Physical Disability
Patient-Centered, Interprofessional Approach to Improve Functional Outcomes in a Skilled Nursing Facility
During a hospital stay, older adults often become physically deconditioned and lose their ability to perform activities of daily living.
- Trial name
- NCT04300413
- Testing
- High-Intensity Rehabilitation plus Mobility (HeRo)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Colorado, Denver
Stroke, Physical Disability
Concomitant Sensory Stimulation During Therapy to Enhance Hand Functional Recovery Post Stroke
The objective of this study is to determine if combining vibration with hand task practice is superior to hand task practice alone.
- Trial name
- NCT04569123
- Testing
- real stimulation, No stimulation
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Medical University of South Carolina
Low Back Pain
The Back Exercises to Neutralize Disability Study
A pilot randomized control trial (RCT) to generate effect sizes on the effects of blood flow restricted exercise on trunk extensor cross-sectional area (primary outcome), strength and endurance, whole body and regional lean mass…
- Trial name
- BEND (NCT02308189)
- Testing
- Exercise with blood flow restriction, Exercise
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Ohio University
Neck Pain
Muscle Energy Technique and Static Stretching on Pain Intensity and Functional Disability in Patients With Mechanical Neck Pain
Neck pain is becoming increasingly common throughout the world with a considerable impact on individuals, communities, health-care systems and businesses (Hoy et al, 2011).Neck pain is a common problem within our society…
- Trial name
- MET&SSinNckp (NCT04350918)
- Testing
- Muscle Enery Techniques, Static Stretching
- Where
- Nigeria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University
Perinatal Condition, Neurodevelopmental Disorders
Perinatal and Psychological Correlates of Neurodevelopmental Disorders in Children.
The goal of this observational study is to investigate perinatal, cognitive and social-emotional correlates of neurodevelopmental disorders and educational difficulties in children and adolescents.
- Conditions
- Perinatal Condition, Neurodevelopmental Disorders, Social Functioning, Child Development
- Trial name
- NCT06215092
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Tennis Elbow, Lateral Epicondylitis
Comparative Effects of Sustained Stretch and Mobilization With Movement in Patient With Tennis Elbow
Tennis elbow, clinically known as lateral epicondylitis, is a prevalent musculoskeletal issue marked by pain and tenderness on the outer part of the elbow.
- Trial name
- NCT06674434
- Testing
- Mobilization with Movement, Sustained Stretch
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Visual Acuity at Near, Accuracy of Accommodation
The Effect of Bifocals in Children With Down Syndrome
Visual acuity at near improves in children with Down syndrome using bifocals
- Conditions
- Visual Acuity at Near, Accuracy of Accommodation, Prevention of Strabismus, Task Readiness
- Trial name
- NCT02241356
- Testing
- bifocals, single vision glasses
- Where
- Netherlands
- Volunteers
- 120 people
- Sponsor
- Radboud University Medical Center
Periodontal Disease, Chronic Neck Pain
Association Between Periodontal Disease and Chronic Neck Pain
This study investigates whether there is an association between periodontal disease (gum disease) and chronic neck pain and related functional disability.
- Trial name
- NCT07711431
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Back Pain
Comparative Effects of Soft Tissue Mobilization and Pressure Therapy With and Without Dynamic Cupping on on Pain and Disability in Patients With Thoracic Back Pain.
This study aims to compare the sequential effects of Instrument-Assisted Soft Tissue Mobilization (IASTM) and Transverse Oscillatory Pressure (TOP), with and without Directional Dynamic Cupping, in patients with thoracic back…
- Trial name
- NCT07892066
- Testing
- Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP), Instrument assisted soft tissue (IASTM), Transvers oscillatory pressure (TOP) and Directional dynamic cupping
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- University of Management and Technology Lahore
Distress, PTSD
Scaling-up Psychological Interventions With Syrian Refugees in Switzerland (STRENGTHS_CH): RCT
The current refugee crisis across the Middle East and Europe has large effects on individual refugees' psychological well-being, as well as on the healthcare systems of countries hosting refugees.
- Conditions
- Distress, PTSD, Anxiety, Depression
- Trial name
- NCT04574466
- Testing
- Problem Management Plus
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- University of Zurich
Aging, Cognitive Decline
Blood Flow Restriction and High-intense Resistance Training in Aging: Interactions Between Neuroplasticity and Muscle
BRAIN-M is a randomized controlled trial designed to examine the effects of a single bout or 12 weeks of blood-flow restriction training or high-intensity resistance training on cognitive function, brain health, muscular…
- Conditions
- Aging, Cognitive Decline, Sarcopenia, Frailty
- Trial name
- BRAIN-M (NCT05744167)
- Testing
- BFRT, MDRT
- Where
- Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Down Syndrome
Effect of Neuro Developmental Therapy in Infants With Down Syndrome
Neurodevelopmental treatments are a progressive therapeutic method experienced thru qualified therapists for the improvement in affected ones.
- Trial name
- NCT04816409
- Testing
- conventional therapy, Neurodevelopmental therapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Trapezitis
Effects of Myofascial Release Versus Dry Cupping on Pain, Muscle Length, and Functional Disability in IT Professionals With Trapezitis.
This study aims to evaluate the effectiveness of two physiotherapy techniques-Myofascial Release and Dry Cupping-in improving pain, muscle length, and functional disability in IT professionals with trapezitis.
- Trial name
- NCT07731763
- Testing
- Myofascial Release, Dry Cupping
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Aging, Mortality
Longevity Metrics AI/ML Development Study
This study builds AI models that score diagnostic screening tests, and that predict screening results, clinical judgment, and life expectancy.
- Conditions
- Aging, Mortality, Cardiovascular Disease Prevention, Metabolic Syndrome
- Trial name
- NCT07808619
- Testing
- AIML scored health screening battery
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.