Clinical trials: Functional Disability, open to volunteers
Anterior Cruciate Ligament Injuries
Perturbation Training vs Functional Activities on Pain, ROM, Balance, and Function Post-ACL
Anterior cruciate ligament (ACL) injuries are among the most common and functionally disabling knee injuries, particularly in physically active individuals.
- Trial name
- NCT07642752
- Testing
- Perturbation Training Group, Task-Oriented Functional Activities Group, Control Group (Standard Rehabilitation Protocol)
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Pubic Symphysis Diastasis
Effects of Pelvic Floor Exercises and Pelvic Support Belt in Symphysis Pubis Dysfunction
Symphysis Pubis Dysfunction (SPD) is a medical condition that affects the pelvic region, particularly the joint that joins the two pubic bones at the front of the pelvis, the pubic symphysis.
- Trial name
- NCT07440862
- Testing
- pelvic floor excercises, pelvic support belt
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Quality of Life, Depression
CAPABLE Transplant
The purpose of this mixed methods study is to adapt CAPABLE as CAPABLE Transplant to accomplish two things: 1) To resolve barriers to being classified as active on the Kidney Transplant (KT) waitlist, 2) as a surgical…
- Conditions
- Quality of Life, Depression, End Stage Renal Disease, Disability Physical
- Trial name
- NCT06326905
- Testing
- CAPABLE Transplant- Open Label Pilot, CAPABLE Transplant- Randomized Control Trial
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Johns Hopkins University
Sacroiliac Joint Dysfunction
Combined Effects of Mulligan's Mobilization With Movement and Kinetic Control Training on Pain, Range of Motion, Gait and Functional Disability Among Patients With Sacroiliac Joint Dysfunction
Sacroiliac joint dysfunction (SIJD) is a frequent source of low back and pelvic pain and contributes significantly to movement restriction, altered gait patterns, and functional disability in adults.
- Trial name
- MWM KCT SIJD (NCT07529093)
- Testing
- Kinetic Control + Mobilization with Movement, Mobilization with Movement
- Where
- 2 sites in Pakistan
- Volunteers
- 55 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Intensive Care Unit Syndrome, Intensive Care Neuropathy
Recovery From ICUAW Following Severe Respiratory and Cardiac Failure
To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO).
- Conditions
- Intensive Care Unit Syndrome, Intensive Care Neuropathy, Intensive Care (ICU) Myopathy, Acute Respiratory Distress Syndrome
- Trial name
- CLEVERER (NCT03753412)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Barts & The London NHS Trust
Down Syndrome
Nordic Walk on Balance and Functional Strength in Children With Down Syndrome
Down syndrome (DS) is one of the more commonly occurring genetic disorders, where mental retardation is combined with nutritional diseases.
- Trial name
- NCT06943508
- Testing
- Conventional Therapy, Nordic Walk
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Developmental Delay
Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental Disorder
Background: People show changes in brain activity when they watch other people do actions. This may be part of early social and communication skills.
- Trial name
- NCT03307317
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
STROKE, Rehabilitation Outcome
Prospective Evaluation of Atrial Fibrillation-Related Stroke Patients in Rehabilitation Program (PEARL), an Observational Cohort Study
The goal of this observational study is to determine if rehabilitation program intensity impacts functional recovery and specific needs in adult ischemic stroke patients who require inpatient rehabilitation.
- Conditions
- STROKE, Rehabilitation Outcome, Brain Disease, Cardiovascular Disease Acute
- Trial name
- PEARL (NCT07253974)
- Testing
- Rehabilitation program based on Physiotherapy, occupational therapy and swallow and language therapy
- Where
- Spain
- Volunteers
- 213 people
- Sponsor
- Parc de Salut Mar
Lumbar Disc Herniation
Evaluation of the Effectiveness of Focused Radiofrequency (TECAR) Therapy on Pain, Disability, Function, and Quality of Life in Patients With Lumbar Disc Herniation
Low back pain is a very common health problem in societies, regardless of the underlying cause. Its lifetime prevalence has been reported to be as high as 75-80%.
- Trial name
- TECAR THERAPY (NCT07335718)
- Testing
- TECAR THERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara City Hospital Bilkent
Nonspecific Neck Pain
Effects of Cailliet and Kendall Exercises in Nonspecific Neck Pain
Objective of study will be to compare effects of Cailliet and Kendall exercises on pain, functional movement and disability in non-specific neck pain.This randomized clinical trial will be conducted at Good Hands Physiotherapy…
- Trial name
- NCT06875856
- Testing
- Kendall exercises, Cailliet exercises
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Obstructive Sleep Apnea, Down Syndrome (Trisomy 21)
Effects of a Pacifier on Obstructive Sleep Apnea and Its Repercussions in Infants With Down Syndrome
Obstructive Sleep Apnea (OSA) is characterised by repetitive collapse of the upper airway during sleep, inducing breathing disturbances that can result in oxygen desaturation and frequent arousals.
- Trial name
- TET21 (NCT07658053)
- Testing
- CURAPROX pacifier use, Pacifier diary, Polysomnography (PSG) to explore OSA
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Down Syndrome, Autonomic Dysfunction
Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome
Down syndrome (DS), the most common genetic cause of intellectual disability, is associated with widespread organ dysfunction, including abnormalities in the autonomic nervous system (ANS).
- Trial name
- DIVE (NCT07238465)
- Testing
- Cold Stress, Maximal Dynamic Exercise, Isometric Handgrip Exercise with Post-Exercise Muscle Ischemia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Non Specific Chronic Neck Pain
Effects of Active Release Technique Versus Stecco Facial Manipulation in Patient With Chronic Non-specific Neck Pain
Non-specific pain that originates from the superior nuchal line and extends to the first thoracic vertebrae. It is exacerbated by sustained neck postures, neck movements or cervical muscle palpation.
- Trial name
- NCT07724600
- Testing
- Active Release Technique, STECCO Method
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Periodontal Disease, Chronic Neck Pain
Association Between Periodontal Disease and Chronic Neck Pain
This study investigates whether there is an association between periodontal disease (gum disease) and chronic neck pain and related functional disability.
- Trial name
- NCT07711431
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Down Syndrome, Trisomy 21
Executive Function Play Opportunities for Children With Down Syndrome
The Executive Function Play Opportunities (EXPO) study is a sequential, multiple assignment, randomized trial (SMART) evaluating adaptive caregiver-mediated intervention pathways for improving executive function (EF) in children…
- Trial name
- EXPO (NCT07792382)
- Testing
- EXPO, EXPO Extended, EXPO Foundations
- Where
- 2 sites in United States, Italy
- Volunteers
- 150 people
- Sponsor
- Colorado State University
Episodic Migraine, Chronic Migraine
CGRP Inhibition, Autonomic Function, and Migraine
The purpose of this clinical study is to better understand the function of the autonomic nervous system in patients with migraine. We aim to understand whether the autonomic functions change depending on the migraine status (i.e.
- Trial name
- CGRP-1 (NCT04628429)
- Testing
- Erenumab, Galcanezumab, Fremanezumab
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Trapezitis
Effects of Myofascial Release Versus Dry Cupping on Pain, Muscle Length, and Functional Disability in IT Professionals With Trapezitis.
This study aims to evaluate the effectiveness of two physiotherapy techniques-Myofascial Release and Dry Cupping-in improving pain, muscle length, and functional disability in IT professionals with trapezitis.
- Trial name
- NCT07731763
- Testing
- Myofascial Release, Dry Cupping
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Rounded Shoulder Posture
Comparative Effects of Eloda With/Without Muscle Energy Technique in Patient With Quadratus Lumborum Syndrome
The aim of the study is to compare effects Comparison of Pilate exercises with and without whole body vibration on posture, disability and pain in patients with upper cross syndrome.
- Trial name
- NCT06732765
- Testing
- Pilates exercise program, Traditional physical therapy program
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Riphah International University
Text Neck Syndrome
Comparing Muscle Energy Technique and Bowen Therapy for Pain, Movement, and Disability in Text Neck Syndrome
This study compared the effects of Muscle Energy Technique and Bowen Therapy on patients with Text Neck Syndrome's pain, function ROM, and posture. Today, text neck syndrome is a growing issue.
- Trial name
- NCT07189351
- Testing
- Bowen Therapy, Muscle Energy Technique (Post-Isometric Relaxation)
- Volunteers
- 78 people
- Sponsor
- University of Lahore
Physical Disability, Cognitive Dysfunction
Study on Cardiovascular Health, Nutrition and Physical Functioning in Older Adults in Spain
Population aging makes it necessary to identify factors related to unhealthy aging. The purpose of this study is to examine the association between ideal cardiovascular health, diet and other lifestyles and biological risk…
- Trial name
- Sen-ENRICAII (NCT03541135)
- Where
- Spain
- Volunteers
- 4,000 people
- Sponsor
- Universidad Autonoma de Madrid