Clinical trials: Functional Disorder
Irritable Bowel Syndrome
Effect of MethylceIlulose or Psyllium on Fermentation of Inulin Assessed Using a Gas Sensing Capsule
The investigators plan to measure the local (in vivo) production of hydrogen when methylcellulose is ingested, to see if the investigators can show a shift of the site of fermentation to the distal colon.
- Trial name
- REALISTIC (NCT06551948)
- Testing
- psyllium, methylcellulose, maltodextrin
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Cardiovascular Disease
Fitness and Daily Function in Adults
The purpose of this study is to examine the impact of aerobic fitness on the ability of able and disabled older adults to perform daily functional activities.
- Trial name
- NCT00018265
- Testing
- Task specific endurance training, Tai Chi
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Cocaine Dependence
Measuring Distress Tolerance With Functional MRI
Background: People who are in treatment for substance abuse often feel distress during the withdrawal period and afterward. Some individuals feel distress more acutely than others, and this distress has been linked to poor…
- Trial name
- NCT01038232
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
IUGR, Fetal Growth Retardation
Cardiac Displacement From Third Trimester to Early Childhood
The aim is to increase awareness of the relationship between (IUGR) and cardiac function in the foetus, the development of cardiac function over time after delivery and what significance a possible early disturbed myocardial…
- Conditions
- IUGR, Fetal Growth Retardation, Intrauterine Growth Restriction
- Trial name
- CADETTE (NCT02583763)
- Testing
- Echocardiography, Blood sample
- Where
- 2 sites in Sweden
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Mild Cognitive Impairment, Cognitive Decline
Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging
The study will examine whether 5mg melatonin (over the counter, OTC) over a 9-month period improves Alzheimer's disease (AD) biomarkers and cognitive function in two groups of individuals: those with mild cognitive impairment…
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Healthy Aging
- Trial name
- NCT03954899
- Testing
- melatonin
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Natalie Denburg
Exostoses, Multiple Hereditary
Height, Ulnar Length and Forearm Function in Multiple Hereditary Exostoses
the purpose of the present registry is to describe the epidemiology of forearm deformities in patients with Hereditary Multiple Exostoses and to identify, independent predictors of severity of the disease and potential…
- Trial name
- NCT05914298
- Testing
- blood and buccal swab genetic test, PUL, Range of motion
- Where
- Italy
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4
Physiopathology of Neuromuscular Function Related to Fatigue in Chronic Renal Disease
Chronic Kidney Disease (CKD) induces many metabolic troubles especially for the advanced CKD (stage 3b-5) patients and their prevalence and importance grow with the deterioration of the glomerular filtration rate (GFR).
- Conditions
- Chronic Kidney Disease Stage 3B, Chronic Kidney Disease stage4, Chronic Kidney Disease Stage 5, Fatigue
- Trial name
- PIONEER (NCT04330807)
- Testing
- Handgrip fatigability test, Questionnaires
- Where
- France
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier le Mans
Alzheimer Disease
Enhancing Consent for Alzheimer's Research
The purpose of this study is to evaluate the efficacy of an enhanced consent procedure for patients with mild-to-moderate Alzheimer disease, and to identify factors and patient characteristics that predict the degree to which…
- Trial name
- BWP-AD (NCT00453544)
- Testing
- Enhanced Consent Procedure, Routine Consent Procedure
- Where
- United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Carpal Tunnel Syndrome
Treatment Intervention of Patients With Carpal Tunnel Syndrome (CTS)
The purpose of this study was to investigate the effectiveness of KT versus TENS combining self-myofascial stretching in treatment of CTS through clinical, functional assessment and sensory measurements.
- Trial name
- NCT06464809
- Testing
- kinesio taping (KT)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Stroke
Prognostic Value for Predicting Outcome Using Functional Near-infrared Spectroscopy in Stroke Rehabilitation
To investigate the prognostic value of Functional Near-Infrared Spectroscopy (fNIRS) in stroke rehabilitation with serial measurements.
- Trial name
- NCT04288414
- Testing
- functional near-infrared spectroscopy
- Where
- South Korea
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Stroke, Transcranial Direct Current Stimulation
Hemodynamic Response of Anodal Transcranial Direct Current Stimulation Over the Cerebellar Hemisphere in Healthy Subjects
Upper extremity motor impairment is one of the major sequelae of stroke, resulting in limitation of activities of daily livings.
- Conditions
- Stroke, Transcranial Direct Current Stimulation, Functional Near Infrared Spectroscopy
- Trial name
- NCT04101695
- Testing
- tDCS
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Muscular Atrophy
Biological and Functional Markers for Precision Astronautical Biomedicine
In the current study the investigators will study early biomarkers of human degradation. In 10-day horizontal bed rest the investigators will enroll 10 healthy male subjects (18-30years, BMI 20-28kg/m2).
- Trial name
- MARS-PRE (NCT04081467)
- Testing
- Bed rest
- Where
- Slovenia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Science and Research Centre Koper
Cognitive Decline
Cognitive Training and Social Interaction Effects on Cognitive Performance of Older Adults
Aging is associated with a decline in almost all aspects of cognitive functions, particularly memory. Recent research suggests that combining cognitive training with ongoing social interaction may aid in improving cognitive…
- Trial name
- NCT05016336
- Testing
- Social interaction combined with cognitive training based on mnemonic strategies., Social interaction group
- Where
- Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Obesity
Mobility & Vitality Lifestyle Program
MOVE UP is a weight management program for adults 60-75 in community settings led by trained community health workers.
- Trial name
- MOVE UP (NCT02657239)
- Testing
- MOVE UP
- Where
- United States
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Renal Impairment
Assessment of Renal Function by Multiparametric MRI
Metabolic syndrome is a collection of conditions that affect at least three of the following five criteria: abdominal obesity, high blood pressure, high fasting glucose levels, high triglyceride levels, and low levels of…
- Trial name
- NCT06407375
- Testing
- mpMRI
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Secondary Hypogonadism
Evaluation of Pharmacokinetic and Safety Profile of Androxal in Male Subjects With Impaired Renal Function
To determine and compare the pharmacokinetics (PK) of a single dose of 25 mg Androxal in overweight male subjects with various stages of renal impairment and in volunteers with normal renal function.
- Trial name
- NCT01923857
- Testing
- Androxal 25 mg
- Where
- 2 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Repros Therapeutics Inc.
Down Syndrome (Trisomy 21)
Vascular Function in Adults With Down Syndrome
Adults with Down syndrome (Ds) are often thought to have a lower risk of heart and blood vessel disease because they tend to have lower blood pressure (BP) and fewer heart attacks than people without Ds.
- Trial name
- VDS (NCT07630207)
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Interstitial Cystitis, Irritable Bowel Syndrome
MAPP Investigation of Pelvic Floor-Brain Neurobiologic Axis in IC/IBS and IBS
Hypotheses: 1. The bidirectional signaling between the cortex, and the pelvic floor/gut is deranged in patients with IC and in IBS.
- Trial name
- NCT01280864
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Augusta University
Femoroacetabular Impingement Syndrome, Healthy Participants
Mobility, Strength, and Functional Outcomes Before Surgery, at 3 Months, and at 6 Months After Hip Arthroscopy for Femoroacetabular Impingement Syndrome
The aim of this study is to identify the factors associated with successful rehabilitation following hip arthroscopy for femoroacetabular impingement syndrome and to highlight any persistent functional deficits at different key…
- Trial name
- NCT07472400
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Liege
Idiopathic Pulmonary Fibrosis, Healthy
Determining in Vitro Properties of Epithelial Cells From Individuals With Genetic Variants Associated With Idiopathic Pulmonary Fibrosis
The investigators are trying to understand the role of specific genes in the function of airway surface cells. The investigators know that there are some common genetic markers that are associated with various lung diseases.
- Trial name
- NCT02187393
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver