Clinical trials: Functional Disorder
Venous Insufficiency
The Effects of Compression Stockings on Pressure Parameters in Patients With Chronic Venous Insufficiency
The main objective of this study is to obtain data to determine, in each individual with and without wearing compression stockings of different strengths and during different postures, the relationship between interface pressure…
- Trial name
- MACIVC (NCT01558024)
- Testing
- Intravenous pressure and intramuscular pressure measurement
- Where
- 2 sites in France
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chronic Renal Insufficiency, Renal Osteodystrophy
Clinical Observation on Bone Metabolism Induced by Chronic Renal Insufficiency
Patients with chronic renal insufficiency usually develop secondary osteoporosis or bone loss, which is called renal osteodystrophy.
- Trial name
- NCT02147782
- Where
- 4 sites in China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
MCI, Mild Cognitive Impairment
The Interactive Physical and Cognitive Exercise System (v3) for Mild Cognitive Impairment (MCI)
The primary purpose of this study is to attempt to replicate and extend promising pilot findings regarding the cognitive benefits of in-home neuro-exergaming with iPACES (interactive Physical and Cognitive Exercise System v3) for…
- Conditions
- MCI, Mild Cognitive Impairment, Alzheimer Disease, Dementia
- Trial name
- iPACES (NCT05009524)
- Testing
- iPACES (interactive Physical and Cognitive Exercise System), PACE (Physical and Cognitive Exercise)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- iPACES LLC
Autism Spectrum Disorders, Mood Disorders
Multidimensional Measurement of Psychopharmacological Treatment Response
The study examines actigraphic, observational, psychometric and associated repeated measurements obtained prior to and during psychopharmacological treatment.
- Conditions
- Autism Spectrum Disorders, Mood Disorders, Sleep Disorders, Attention Deficit Disorders
- Trial name
- NCT01184235
- Testing
- Pharmacological Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Child Psychopharmacology Institute
Respiratory Disease
Pulmonary Function Test Study - Automated Interpretation
A multicentric study to explore variability when clinicians are intrepreting lung function tests. Comparison with results of in-house built software for automatic interpretation.
- Trial name
- NCT03264417
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Cystic Fibrosis
Assessment of Cognitive Function and Exercise Capacity in Cystic Fibrosis
No studies in the literature have investigated the simultaneous effects of cognitive function, exercise capacity and arterial stiffness in adult patients with CF.
- Trial name
- NCT06175182
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Alzheimer Disease, Mild Cognitive Impairment
Software Validation Study-Cognitive Status Indicator
The SPARK Cognitive Status Indicator software uses an algorithm to assess a resting state EEG recording as being consistent with a cognitive status of unimpaired, mild cognitive impairment (MCI; MCI AD- or MCI AD+), or dementia…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Dementia
- Trial name
- REMIND-V (NCT06809725)
- Testing
- SPARK Cognitive Status Indicator (software support data collected via EEG)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Spark Neuro Inc.
Dyslipidemia, Oxidative Stress
Brazil Nut Consumption in Microvascular Endothelial Function, Oxidative Stress and Metabolic Abnormalities
The purpose this research is to check the effect of Brazil Nuts consumption in oxidative stress, metabolic abnormalities and microvascular endothelial function dyslipidemic and hypertensive patients.
- Trial name
- NCT01990391
- Testing
- Brazil nut flour
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Dehydration
Hydration Amongst Nurses and Doctors Oncall
The main purpose of this study is to assess and compare the hydration status of medical and nursing staff and to investigate the relationship between the hydration status, cognitive function and serum cortisol (marker of stress).
- Trial name
- HANDsOn (NCT02230774)
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Liver Fat, Cardiac Function
Short-term Fat Overfeeding on the Effects of Liver Metabolism
Despite work showing the overconsumption of saturated fatty acids (SFA) to be metabolically deleterious, debate continues about whether there is a link between SFA and cardiovascular disease risk.
- Conditions
- Liver Fat, Cardiac Function, Lipid Disorder, Adiposity
- Trial name
- FOS (NCT05962190)
- Testing
- Diet
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Hearing Loss, Sensorineural, Bilateral Vestibulopathy
Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects
The world population has been growing and aging dramatically, with a rising prevalence of dementia. Worldwide, around 50 million people have dementia, with 10 million new cases added every year.
- Conditions
- Hearing Loss, Sensorineural, Bilateral Vestibulopathy, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- GECkO (NCT04385225)
- Testing
- Longitudinal follow-up
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Nasal Polyps
Infrazygomatic Versus Intranasal Injection Sphinopalatine Ganglion Blockade Effect on Surgical Field in FESS
This study aimed to show the effect of sphinopalatine ganglion blockade on surgical field, hemodynamics and postoperative pain in FEES operation.
- Trial name
- NCT04996576
- Testing
- infrazygomatic approach sphinopalatine ganglion block, intranasal injection approach of sphinopalatine ganglion block
- Where
- 2 sites in Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Mild Cognitive Impairment (MCI), Major Depressive Disorder, Remitted
Validating the On-line Creyos Cognitive Assessment Platform in Older Adults With Major Depressive Disorder or Mild Cognitive Impairment
The goal of this observational study is to validate the Creyos online cognitive assessment platform in individuals with mild cognitive impairment, or remitted major depressive disorder.
- Conditions
- Mild Cognitive Impairment (MCI), Major Depressive Disorder, Remitted, Healthy Controls Group - Age and Sex-matched
- Trial name
- Creyos-MD (NCT06780917)
- Where
- 3 sites in Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
COVID-19
Brain Function Changes Following COVID-19 Infection
The global COVID-19 pandemic has now led to millions of infections worldwide. It produces long-lasting changes in the general physiology of multiple organs, including the brain.
- Trial name
- NCT05961618
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Hemiplegic Shoulder Pain
"The Effect of Hemiplegic Shoulder Pain on Balance, Upper Extremity Function and Quality of Life"
"The Effect of Hemiplegic Shoulder Pain on Balance, Upper Extremity Function and Quality of Life"
- Trial name
- NCT04292613
- Testing
- "The Effect of Hemiplegic Shoulder Pain on Balance, Upper Extremity Function and Quality of Life"
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Obsessive Compulsive Disorder (OCD)
Transcranial Direct Current Stimulation and Extinction in Obsessive Compulsive Disorder
Obsessive-compulsive disorder (OCD) is associated with substantial impairments in quality of life and is among the most disabling psychiatric disorders.
- Trial name
- NCT06834217
- Testing
- Active transcranial direct current stimulation
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Yale University
HDL
Oral Nutritional Supplement Effect on HDL Function
Evaluate the effects of a proprietary supplement on total HDL, HDL functionality, HDL particle size and HDL particle number (HDL-P)
- Trial name
- NCT04529174
- Testing
- CardioLux™HDL
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Human Cervical Motions
Interexaminer Reliability, Outcomes for Manipulation of Cervical Dysfunction, 3-D Kinematics
The purpose of this project is to quantify 3-dimensional (3-D) cervical motion pattern changes that result from osteopathic manipulation treatment (OMT) in an experimental subject group diagnosed with somatic dysfunction.
- Trial name
- NCT01186718
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Basic Auditory Processes, Emotional Perception
Auditory Processes and Emotional Perception in Schizophrenia
Schizophrenia is a mental illness with a variety of clinical symptoms that can be regrouped into 2 categories: positive and negative symptoms.
- Conditions
- Basic Auditory Processes, Emotional Perception, Source Monitoring Deficits
- Trial name
- AUDISPACE (NCT04768335)
- Testing
- cognitive experiments' session
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Vocal Cord Dysfunction, Vocal Cord Paralysis
Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure
The goal of this prospective, observational study is to evaluate for the presence of vocal fold motion impairment (VFMI) in the children admitted to the pediatric intensive care unit on noninvasive positive pressure ventilation…
- Conditions
- Vocal Cord Dysfunction, Vocal Cord Paralysis, Vocal Cord Paresis, Recurrent Laryngeal Nerve Palsy
- Trial name
- NCT06406725
- Testing
- Point-of-Care Ultrasound of the Airway
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic