Clinical trials: Functional Motor Disorder
Physical Activity, Sedentary Behavior
Exploring Virtual Reality Adventure Training Exergaming
The current project aims to design and implement an 8-week Virtual Reality Adventure Therapy Exergaming (V-RATE) intervention focused on women veterans.
- Conditions
- Physical Activity, Sedentary Behavior, Depression, Cognitive Function
- Trial name
- V-RATE (NCT05563805)
- Testing
- Virtual Reality-based physical activity intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Androgen Insensitivity Syndrome, Metabolic Parameters in AIS, CAIS, PAIS and MAIS
Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity
Background: Androgen effects in humans are usually (but not always) mediated by the androgen receptor which is coded for by the androgen receptor gene (AR gene).
- Conditions
- Androgen Insensitivity Syndrome, Metabolic Parameters in AIS, CAIS, PAIS and MAIS, Tumor Formation in AIS, CAIS, PAIS and MAIS, Sexual Function AIS, CAIS, PAIS and MAIS
- Trial name
- NCT04708431
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Lifestyle-related Condition
Prevention of Lifestyle-related Disorders Based on Functional Examinations
The goal of this randomised controlled trial is to examine the effects of functional examinations and feedback/support on healthy 40-year-olds.
- Trial name
- PREVFUNKTION (NCT06309342)
- Testing
- PREVFUNKTION, Control
- Where
- 2 sites in Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Lena Bornhoft
Healthy Individuals (Controls), Parkinson Disease
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
- Conditions
- Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
- Trial name
- Allena-mente (NCT07066137)
- Testing
- CAREN, Control group
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Stroke
Proximal Priority Versus Distal Priority Robotic Priming Effects in Patients With Chronic Stroke
This is a single-blind randomized comparative efficacy study involving 54-72 participants with chronic stroke. Participants will be randomized into proximal priority robotic group or distal priority robotic group and receive 18…
- Trial name
- NCT04446273
- Testing
- Bi-Manu-Track
- Where
- 4 sites in Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Type 2 Diabetes Mellitus, Cardiovascular Diseases
Physical Activity, Insulin Resistance and Function of Fat Tissue in the Offspring of Patients With Type 2 Diabetes
Offspring of patients with type 2 diabetes have increased risk of developing diabetes and are typically more insulin resistant than their peers with no diabetes family history.
- Trial name
- NCT00268541
- Testing
- Physical activity
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Juvenile Idiopathic Arthritis
Immersive Virtual Reality Exergaming Program in Adolescents Diagnosed With Juvenile Idiopathic Arthritis
The aim of the study is to investigate the effect of home-based exercise program versus personalized IVR exergame (Fit-XR) program on physical fitness, functional capacity and physical activity in adolescents with Juvenile…
- Trial name
- JiaFiT-XR (NCT06176846)
- Testing
- Immersive Virtual Reality Exergaming Program, Home-Based Exercise Program
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Spinal Muscular Atrophy Type 3, Duchenne Muscular Dystrophy (DMD)
Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders
The purpose of this research is (1) to identify disease specific walking-related digital biomarkers of disease severity, and (2) monitor longitudinal changes in natural environments, for extended periods of time, in DMD and SMA.
- Trial name
- NCT06839469
- Where
- 3 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Columbia University
Back Pain, Low
Effects of Mackenzie and Tailored Mat Exercises in Post-Menopausal Women With Low Back Pain
Group A will receive tailored mat exercises. Group B will receive Mckenzie exercises. A baseline treatment including moist hot pack and TENS will be given to both of these groups.
- Trial name
- NCT06750380
- Testing
- Tailored mat exercise program, McKenzie exercises
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Frailty Syndrome, Cognitive Impairment
Successful Aging and Frailty
Frailty is the term commonly utilized to describe the geriatric syndrome that exposes the elderly to increased risk of negative health-related events.
- Conditions
- Frailty Syndrome, Cognitive Impairment, Sarcopenia
- Trial name
- SAFe (NCT03963050)
- Testing
- Exercise Training, Exercise Training + Cognitive Training, Control
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Spinal Cord Injuries
Functional Interval Training for People With Spinal Cord Injury and Their Care Partners
Functional Interval Training for People with Spinal Cord Injury and Their Care Partners (SCI-FIT) aims to address barriers to physical activity for people with spinal cord injury and their care partners.
- Trial name
- SCI-FIT (NCT05221723)
- Testing
- High Intensity Interval Exercise Training Group
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Parkinson Disease, Physical Activity
Physical Training Induced Plasticity of Motor Control Mechanisms in Parkinson's Disease Patients
There are experimental evidences of the important role of exercise in the PD, that induces similar effects to pharmacotherapy. So far, the mechanisms of the impact of these changes on the brain subcortical and cortical regions…
- Trial name
- NCT03753503
- Testing
- exercise, conventional physical therapy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Agitated; State, Acute Reaction to Stress
Preemptive Chlorepheniramine Maleate Reducing Postoperative Agitation
The aim of the study is to identify the role of preoperative chlorepheniramine maleate on alleviating or reducing the severity of postoperative agitation following FESS procedures.
- Trial name
- NCT04293081
- Testing
- Preemptive chlorepheniramine maleate intravenous injection, normal saline
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Stroke
Motor Relearning Program and Aerobic Exercise in Postural Stability and Lower Limb Function in Subacute Stroke Patients
The aim of the study is to determine combined effects of MRP and aerobic exercise in postural stability and lower limb function in subacute stroke patients
- Trial name
- NCT06476782
- Testing
- Motor Relearning Program(MRP) and aerobic exercise, Motor Relearning Program(MRP)
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Stroke, Stroke with Hemiparesis
Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spectroscopy (fNIRS)
The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy…
- Conditions
- Stroke, Stroke with Hemiparesis, Stroke, Ischemic
- Trial name
- NCT06806397
- Testing
- Stimulus response task
- Where
- 2 sites in Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Intestinal Inflammation, Metabolic Disease
The Role of Regular Physical Activity in Enhancing Metabolic Health, Reducing Inflammation, and Improving Gut Function
The goal of this clinical trial is to learn if regular physical activity can improve metabolic health, reduce inflammation, and decrease gut permeability in individuals aged 50 and older.
- Trial name
- NCT06606678
- Testing
- Exercise
- Where
- Poland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Amyotrophic Lateral Sclerosis
Relationship Between Respiratory Functional Tests and Image Thoracic Techniques in Patients With Neuromuscular Diseases
It is very important monitoring respiratory muscle function in patients with amyotrophic lateral sclerosis (ALS). We have at our disposal Respiratory Functional Tests (forced vital capacity (FVC), maximal mouth-inspiratory force…
- Trial name
- NCT01090674
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Stroke
Non-Invasive Brain Signal Training to Induce Motor Control Recovery After Stroke
The purpose of this trial was to evaluate the benefits of combination motor learning training and brain computer interface training for restoring arm function in people with stroke.
- Trial name
- NCT00746525
- Testing
- Surface functional electrical stimulation (FES), Motor learning, Brain computer interface (BCI) training
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Louis Stokes VA Medical Center
Sedentary Behavior, Affect
Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
The overall objective of this in-lab randomized controlled trial is to test the efficacy of multi-day interruptions in sedentary behavior vs.
- Conditions
- Sedentary Behavior, Affect, Metabolic Disturbance, Anxiety
- Trial name
- NCT04469790
- Testing
- SIT+WALK, EX
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity, Type 2 Diabetes Prevention
The Medical College of Georgia PLAY Project: Exercise Dose and Insulin Sensitivity in Obese Children
The study is a behavioral clinical trial of aerobic exercise to determine dose-response effects on risk for type 2 diabetes, fatness, fitness, blood cholesterol levels, and other cardiovascular risk factors in overweight…
- Conditions
- Obesity, Type 2 Diabetes Prevention, Executive Function (Cognition)
- Trial name
- NCT00108901
- Testing
- Aerobic exercise program
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)