Clinical trials: Functional Motor Disorder
Ketosis, Metabolic, Immune Functions
The Effect of Acute Exogenous Oral Ketone Supplementation on Immune Cells Function and Immune Cells Histone Β-hydroxybutyrylation
To conduct a single-arm pilot study to determine how acute ingestion of an exogenous ketone monoester supplement alters the histone lysine β-hydroxybutyrylation and immune function in healthy human monocytes and lymphocytes.
- Conditions
- Ketosis, Metabolic, Immune Functions, Histone Deacetylase (HDAC) Activity
- Trial name
- Acute_Ketone (NCT06590623)
- Testing
- Ketone Monoester (KE)
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Heart Failure, Diastolic
Respiratory Muscle Function in Heart Failure
This study is being done because investigators are trying to determine how respiratory muscle and lung function influence the exercise responses in heart failure and healthy participants.
- Trial name
- NCT03924479
- Testing
- PowerBreathe (Breathing muscle training)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cerebral Palsy, Infant Development
Neuroimaging of Babies During Natural Sleep to Assess Typical Development and Cerebral Palsy
Background: Early diagnosis of cerebral palsy (CP) is crucial, enabling intervention when neuroplasticity is at its highest. Magnetic resonance imaging (MRI) plays a vital role in CP diagnosis.
- Conditions
- Cerebral Palsy, Infant Development, Development, Infant
- Trial name
- NIBS-CP (NCT06396520)
- Testing
- No intervention, observational
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danish Research Centre for Magnetic Resonance
Neurological Disorders, Cognitive Impairment
Validation of the VIRADIA App for Neurological and Cognitive Diagnostics in Virtual Reality
The VIRADIA study aims to validate and assess the reliability of a newly developed Virtual Reality (VR) diagnostic platform designed for neurological and cognitive testing.
- Conditions
- Neurological Disorders, Cognitive Impairment, Motor Impairment, Neurodegenerative Diseases
- Trial name
- VIRADIA (NCT07268079)
- Testing
- VIRADIA - Virtual Reality Diagnostic Platform
- Where
- Slovakia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Gametherapy
Multiple Sclerosis
Upper Airway Function and Cardiorespiratory Performance in Impair Trunk Motor Control Multiple Sclerosis Patients.
Multiple sclerosis is a chronic and highly disabling disorder with considerable social impact and economic consequences. It is caused by damage to the myelin sheath, the protective covering that surrounds nerve cells.
- Trial name
- NCT04252599
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Down Syndrome, Autonomic Dysfunction
Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome
Down syndrome (DS), the most common genetic cause of intellectual disability, is associated with widespread organ dysfunction, including abnormalities in the autonomic nervous system (ANS).
- Trial name
- DIVE (NCT07238465)
- Testing
- Cold Stress, Maximal Dynamic Exercise, Isometric Handgrip Exercise with Post-Exercise Muscle Ischemia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Primary Immune Deficiency, Exercise Capacity
Evaluation of Adult Patients With Immunodeficiency Within the Scope of the ICF
Primary immunodeficiency is a clinically, immunologically, and genetically heterogeneous group of diseases that occur as a result of quantitative and/or qualitative deficiency of one or more cellular and molecular components…
- Conditions
- Primary Immune Deficiency, Exercise Capacity, Physical Activity, Quality of Life
- Trial name
- NCT06014463
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Unspecified Disorder of Vestibular Function, Bilateral
Biological Rhythms and Vestibular System
The purpose of this study is to study the relationship between the vestibular system and chronobiology
- Trial name
- REHAB_Rn'V (NCT01839409)
- Testing
- vestibular stimulation
- Where
- France
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Lifestyle Risk Reduction
Prevention of Lifestyle-related Ill-health With Early Functional Examinations and Individualized Risk Profiles
Background: Many lifestyle-related health disorders are influenced by physical activity level and physical function. Health examinations which focus on musculoskeletal function of people who have risk factors for…
- Trial name
- PREVFUNKTION (NCT05535296)
- Testing
- Risk profile
- Where
- Sweden
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Lena Bornhoft
Vasodilation, Exercise
Acute Effect of Polyphenols Supplementation on Endothelial Function and Exercise Related Markers, in Physically Active Healthy Volunteers.
To evaluate the effect of acute polyphenols supplementation on vasodilation and related markers along with exercise related markers (notably performance, respiratory exchanges, perceived exertion), before, during and after a…
- Conditions
- Vasodilation, Exercise, Healthy Adults
- Trial name
- PolypOxy (NCT07518758)
- Testing
- Oral administration
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Nexira
Motor Neuron Disease
Brain Function in Primary Lateral Sclerosis
This study will examine whether the motor cortex (the part of the brain that controls movement) works properly in patients with primary lateral sclerosis (PLS), a disorder in which voluntary movements are very slow.
- Trial name
- NCT00071435
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
The Autonomic Nervous System State and Response to Different Stimuli Among Patients Post Stroke: A Follow-up Study
The study describes the autonomic control system function in subjects post stroke in comparison with healthy subjects. Aims: To describe the Autonomic hart rate control system function in post stroke subjects in different…
- Trial name
- NCT01632410
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Medulloblastoma, Childhood, Healthy Volunteers
Child's Study of the Impact of PF Lesion on Motor Skills, Language, Cognitive Functioning and Social Cognition
One of the major complications of posterior fossa surgery is Posterior Fossa Syndrome (PFS). This syndrome is due to a possible complication of surgical excision of a tumor of the cerebellum (4th ventricle) and is characterized…
- Conditions
- Medulloblastoma, Childhood, Healthy Volunteers, Fossa Posterior Tumor, Low-grade Glioma
- Trial name
- CervIRM (NCT04174820)
- Testing
- Functional Magnetic Resonance Imaging (fMRI)
- Where
- 5 sites in France
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Celiac Disease in Children, Celiac Disease in Adolescents
Effect of Adherence to a Gluten-Free Diet on Cognitive and Motor Dual-Task Performance in Adolescents Diagnosed With Celiac Disease
The aim of this cross-sectional observational study is to comprehensively examine the effects of adherence to a gluten-free diet on cognitive, motor, and psychosocial functions in adolescents aged 8-18 years diagnosed with celiac…
- Trial name
- NCT07382999
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Inonu University
Stroke
Comparison of Effectiveness of Virtual Reality With Mirror Therapy in Improving Motor Function of Upper Limb of Stroke Patients
The purpose of the study is to compare the effectiveness of virtual reality and mirror therapy in stroke patients. Different studies has been done to find out the best therapy for stroke patients.
- Trial name
- NCT05441228
- Testing
- Oculus Quest 2, Mirror therapy box
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Shifa Tameer-e-Millat University
Gulf War Illness, Persian Gulf War Syndrome
Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans
Determine if: genetic differences of CNDP1 gene the previously defined GWI/Chronic Fatigue Syndrome (GWI/CFS) cerebrospinal fluid proteome contents psychometric other variables can differentiate between veterans of the 1990-1991…
- Trial name
- NCT00810225
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Spinal Cord Injury
Eccentric Motor Control After SCI
This project will characterize lower extremity eccentric muscle function among individuals who have undergone locomotor training after spinal cord injury and will evaluate the effect of downhill training at slow to moderate…
- Trial name
- NCT02821845
- Testing
- Untrained and Trained SCI Hip or Knee
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Cerebral Palsy, Bilateral Cerebral Palsy
Effects of HABIT-ILE in Adults with Bilateral Cerebral Palsy
This randomized controlled trial (RCT) aims to evaluate the effects of intensive Hand and Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) in improving body structure, function, daily activities, and…
- Trial name
- NCT06767930
- Testing
- Hand and Arm Bimanual Intensive Therapy Including Lower Extremities, Conventional intervention
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Autism
Motor Function Assessment and VR-based Motor Training in Adults With Autism Spectrum Disorder
The goal of this clinical trial is to learn if autism affect motor functions, including muscle strength, balance, and motor control? Additionally, understanding the motor functions, cognitive functions, and brain activation in…
- Trial name
- NCT07134569
- Testing
- VR-based motor training
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Physical Activity, Functional Performance
Additional Effects of Triamcinolone to Hyaluronic Acid on Knee Osteoarthritis
Using a double-blind, randomized controlled design to investigate the additional therapeutic effects of 3 times of combined triamcinolone and hyaluronic acid injections to 3 times of hyaluronic acid injections to patients with…
- Trial name
- NCT02949466
- Testing
- Triamcinolone, Hyaluronic acid
- Where
- Taiwan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University