Clinical trials: Functional Motor Disorder
Ischemic Stroke
Correlation Between Brain Structure and Activity and Spontaneous Recovery of Motor Function Following Brain Ischemic Stroke
The investigator aims to find a correlation between brain structure and activity and spontaneous recovery of motor function following brain ischemic stroke by Analysis of MRI scans.
- Trial name
- NCT05889429
- Testing
- MRI scans, clinical assessments
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Technion, Israel Institute of Technology
COVID-19 Respiratory Infection
Cardiopulmonary Rehabilitation in Long COVID-19 Patients With Persistent Breathlessness and Fatigue
The objective of this project is to assess the effects of a 2-month cardiopulmonary rehabilitation program on cardiorespiratory fitness in long COVID19 patients.
- Trial name
- COVID-Rehab (NCT05035628)
- Testing
- Cardiopulmonary exercise training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Louis Bherer
Type 2 Diabetes, Muscular Atrophy
Exercise Training as an Intervention to Improve Muscle Function and Recovery Following Bed Rest in Older Adults With Type 2 Diabetes
The purpose of this research is to gather data on how exercise can help recovery of muscle mass, strength, and physical function after bedrest in older adults with pre-diabetes and type 2 diabetes.
- Conditions
- Type 2 Diabetes, Muscular Atrophy, Sedentary Behavior, Exercise
- Trial name
- RECOVER (NCT04057677)
- Testing
- Bed Rest Intervention, Exercise Program
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Neuromuscular Diseases
Controlled Study of Upper and Lower Limb Movements in Patients Patients with Pathologies That Have an Impact on Ambulation or Motor Function
The main aim of the study is to validate the algorithms developed to analyze the signals from the various sensors contained in the magneto-inertial control units and reconstruct upper and lower limb movements under different…
- Trial name
- NCT06439823
- Testing
- ActiMyo®/Syde®
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Laurent Servais
Tourette's Syndrome, Chronic Motor Tic Disorder
Brain Activation in Vocal and Motor Tics
This study will investigate the brain areas that are activated by vocal and motor tics in patients with Tourette's syndrome and other tic disorders. Tics are involuntary repetitive movements similar to voluntary movements.
- Conditions
- Tourette's Syndrome, Chronic Motor Tic Disorder, Chronic Motor Vocal Disorder
- Trial name
- NCT00026000
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dystonia
Brain Function in Focal Dystonia
Objectives The main objectives of this proposal are (1) to characterize motor learning abnormalities in patients with focal dystonia; (2) to show, using transcranial magnetic stimulation, that this abnormal motor learning went…
- Trial name
- NCT00102999
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Motor Imagery, Neck Pain
Motor Imagery Ability and Cervical Discogenic Pain
Background: The purpose of the study was to examine the motor imagery ability and its association with pain, functional status, neck awareness and depression levels in individuals with cervical discogenic pain (CDP).
- Conditions
- Motor Imagery, Neck Pain, Disc Herniation, Functional Status
- Trial name
- NCT06502236
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Parkinson Disease
Exercise and Sleep in Parkinson's Disease
This study will investigate the impact of two common exercise modalities, cardiovascular and resistance training, on sleep quality and architecture in persons with Parkinson's disease (PD), and whether these potential positive…
- Trial name
- NCT04558879
- Testing
- CT, RT
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McGill University
Multiple Sclerosis, Weakness
Effects of the Cross-Training in Patients With Multiple Sclerosis
The purpose of this study is to determine whether, in patients with multiple sclerosis presenting with marked asymmetry of strength, training the less-affected limb with a Cross-Training approach may induce a meaningful transfer…
- Conditions
- Multiple Sclerosis, Weakness, Fatigue
- Trial name
- CTSM (NCT02010398)
- Testing
- Cross-Training healthy subjects, Cross-Training multiple sclerosis, Standard-training multiple sclerosis
- Where
- 3 sites in Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Cognitive Decline, Dementia
Effects of Strengthening Exercise on the Brain for Early Dementia and Normative Older Adults
This study will evaluate the effects of low-intensity strengthening exercise on the brain (thinking and processing speed) for patients with early dementia, compared with normative older adults.
- Conditions
- Cognitive Decline, Dementia, Alzheimer's Disease, Mild Cognitive Impairment
- Trial name
- NCT01264614
- Testing
- Strengthening exercise
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Union College, New York
Overweight, Exercise
Effects of Diet Versus Diet Plus Aerobic and Resistant Exercise Program in Overweight Women
Adult women aged 18-50 years and overweight (preobese) with a BMI of 25-30 kg/m2 will be included in the study. Participants will participate in an eight-week diet and diet plus aerobic and resistance exercise program.
- Trial name
- NCT05591794
- Testing
- Aerobic and resistance exercises, Diet program, Regular walking program
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Barth Syndrome
Resistance Exercise in Barth Syndrome
Barth syndrome (BTHS) is a disorder that is characterized by heart failure, exercise intolerance and skeletal muscle weakness. Preliminary evidence demonstrates that endurance exercise training does not significantly improve…
- Trial name
- NCT01629459
- Testing
- Resistance exercise and protein supplementation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Charcot-Marie-Tooth Disease Type 1A
Identification of Novel Biomarkers in Early Charcot-Marie-Tooth 1A Disease
This is a 2-year follow-up study of a cohort of 35 CMT1A patients and 20 healthy volunteers. The main objective is identifying prognostic markers for CMT1A using multi-omics analysis.
- Trial name
- CMT-MODS (NCT07049588)
- Testing
- Quantitative neuromuscular MRI, Skin biopsy, Clinical scores
- Where
- France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Acute Mountain Sickness, High Altitude Pulmonary Edema
Sleep and Cerebral Responses to High Altitude
Mechanisms underlying high-altitude intolerance as well as exercise performance limitation in hypoxia still remain to be fully understood.
- Conditions
- Acute Mountain Sickness, High Altitude Pulmonary Edema, High Altitude Cerebral Edema
- Trial name
- VALLOT 2011 (NCT01565603)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Traumatic Brain Injury
Home-Based Exergame Motor-Cognitive Rehabilitation for Traumatic Brain Injury
The goal of this clinical trial is to evaluate the effectiveness of a home-based cognitive-motor telerehabilitation program in individuals with traumatic brain injury (TBI) following discharge from intensive inpatient…
- Trial name
- HOME-TBI (NCT07733336)
- Testing
- HOME-EXER telerehabilitation protocol, OUT-REHAB rehabilitation protocol
- Where
- 2 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Traumatic Brain Injury, TBI (Traumatic Brain Injury)
Cervical Transcutaneous SCS for TBI
The goal of this study is to test the effects of non-invasive electrical stimulation of the spinal cord (called transcutaneous spinal cord stimulation, or tSCS) on arm and hand movement in people with motor impairments after a…
- Trial name
- NCT07147816
- Testing
- Transcutaneous electrical stimulation of the cervical spinal cord (tSCS)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Roberto de Freitas
Spinal Muscular Atrophy
A Pilot Study of Biomarkers for Spinal Muscular Atrophy
The goal of this pilot study is to identify a marker or panel of markers in the blood or urine from a wide range of Spinal Muscular Atrophy (SMA) patients that segregates with measures of clinical severity.
- Trial name
- BforSMA (NCT00756821)
- Where
- 18 sites in United States, Canada
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Osteoarthritis, Hip
Relationship of Core Stability on Pain and Functional Levels in Patients Diagnosed With Hip Osteoarthritis
Osteoarthritis (OA) is a common disease that occurs more commonly amongst the elderly and is caused by the destruction of the joint cartilage.
- Trial name
- NCT04771936
- Testing
- Physiotherapy Exercises
- Where
- Malta
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Malta
Autism Spectrum Disorder, Motor Activity
rTMS to Improve Motor Function in Autism
In the current project, investigators have two main goals: i) Testing whether an excessive plasticity, i.e. hyperplasticity in the motor cortex underlies motor function difficulties in autistic adults, and ii) Using repetitive…
- Trial name
- (AMBLE Autism) (NCT06497920)
- Testing
- Active rTMS to the motor cortex
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Mountain Sickness Acute
Breathing Training to Improve Human Performance at High Altitude
Individuals traveling to altitudes above 8,000 feet may suffer from impaired exercise and cognitive performance, and acute mountain sickness (AMS).
- Trial name
- NCT03530163
- Testing
- Respiratory Muscle Training
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver