Clinical trials: Functional Outcome
Ruptured Anterior Cruciate Ligament, Partial Tear Ligament
Proprioceptive Function, Postural Stability & Clinical Outcome After Stump Preserving Anterior Cruciate Ligament Reconstruction Surgery
Anterior cruciate ligament (ACL) is known to serve a number of functions in the knee joint. Besides providing mechanical stability, it also contributes to proprioceptive function.
- Trial name
- NCT01348945
- Testing
- conventional ACL rehabilitation program
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Chinese University of Hong Kong
Acetabular Fracture
Function Outcome of Impaction Injuries in Acetabular Fractures
Is the anatomical reduction of osteochondral impaction in the acetabular fractures will improve the functional outcome? Despite the increasing amount of literature related to the management of anteromedial dome impactions and…
- Trial name
- NCT03152266
- Testing
- No intervention. Observational study
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
Aortic Stenosis, Hypertension
Transcatheter Aortic Valve Implantation in Western NORway
A prospective study of 600 patients with severe aortic stenosis (AS) and symptoms who underwent TAVI at the Haukeland university hospital, Bergen, Norway.
- Trial name
- TAVI-NOR (NCT04417829)
- Testing
- Biological prosthesis in the aortic valve
- Volunteers
- 600 people
- Sponsor
- Haukeland University Hospital
Frozen Shoulder
Prolotherapy Intervention in Patient With Frozen Shoulder
Introduction : Prolotherapy is regenerative tissue therapy that is considered to be efficacious in reducing symptoms and morbidity of frozen shoulder, but only a few studies demonstrate the effect of prolotherapy at the…
- Trial name
- NCT05131269
- Testing
- Dextrose 15 % in Water, Normal Saline 20 mL Injection
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Bumi Herman
Idiopathic Pulmonary Fibrosis
Reliability of the 4 Metre Gait Speed in Idiopathic Pulmonary Fibrosis
This study is investigating the reliability of the 4 metre gait speed test (4MGS) in patients with a lung disease called Idiopathic Pulmonary Fibrosis (IPF).
- Trial name
- IPFREL (NCT02445157)
- Testing
- 4MGS
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Weight-bearing, Rehabilitation
Influence of an Anti-gravity Treadmill on Functional Outcome in Non-operatively Treated Pelvic Fractures - a Pilot Study
Non-operative treatment of pelvic fractures is possible. Immobilisation implies different adjustment processes. Patients with pelvic ring fractures and partial weight bearing have to obtain theses.
- Trial name
- NCT03206398
- Testing
- anti-gravity treadmill
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Breast Cancer
Quilting Sutures After Mastectomy
The use of wound drains after mastectomy is common practice in Belgium. However, placement of suction drainage has several disadvantages.
- Trial name
- BE-Quilt (NCT06415032)
- Testing
- Mastectomy with Quilting sutures without drain placement, Mastectomy with Conventional sutures with drain placement
- Where
- Belgium
- Volunteers
- 296 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Congestive Heart Failure
Study to Evaluate the Safety of Twice Daily Oral Carvedilol
The objective of this study is to evaluate the long-term safety of carvedilol in pediatric patients with chronic heart failure, who completed the Pediatric Carvedilol Study 321.
- Trial name
- NCT00129363
- Testing
- Carvedilol
- Where
- 17 sites in United States
- Volunteers
- 75 people
- Sponsor
- Shaddy, Robert, M.D.
Spinal Muscular Atrophy
Responsiveness and Validation Study of MFM-20 in SMA Patients Treated With Nusinersen
The Motor Function Measure (MFM), a reliable tool assessing motor function and its progression in most neuromuscular diseases, is widely used in France in many teams.
- Trial name
- RetroNusiMFM (NCT04644393)
- Where
- 8 sites in France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Rotator Cuff Arthropathy or Degeneration of the Glenohumeral Joint with Severe Posterior Wear
Migration and Functional Outcome of DELTA Xtend Reverse Shoulder Lateralized Glenosphere Line Extension System
This is a randomized controlled trial comparing the DELTA Xtend Reverse Shoulder System Lateralized Glenosphere Line Extension (intervention group) with the standard DELTA Xtend Reverse Shoulder System (control group).
- Trial name
- NCT05447819
- Testing
- Reverse shoulder arthroplsaty
- Where
- Denmark
- Volunteers
- 122 people
- Sponsor
- Herlev and Gentofte Hospital
Schizophrenia, Schizoaffective Disorder
Cognitive Remediation in Early Phase Psychosis
The purpose of the study is to investigate the effect of a 30 hour cognitive remediation program for young patients with early phase schizophrenia spectrum disorders on cognitive, clinical and functional outcome measures.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Psychosis NOS
- Trial name
- NCT01546467
- Testing
- Cognitive remediation
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Osteoarthritis of the Knee
Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
The purpose of this study is to test whether surgical insertion of total knee replacement provides further improvement in quality of life, pain and function in addition to an algorithm for systematic non-surgical treatment…
- Trial name
- MEDIC (NCT01410409)
- Testing
- Neuromuscular training (NEMEX-TJR), Paracetamol, Burana
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Psychosocial Functioning, Surgery
Building Resilience for Surgical Recovery
The goal of this clinical trial is to test problem solving therapy (PST) in older adults who are undergoing major surgery. The main question it aims to answer is: What is the feasibility and acceptability of delivering PST to…
- Conditions
- Psychosocial Functioning, Surgery, Older Adults, Physical Function
- Trial name
- BRSR (NCT06174701)
- Testing
- Problem Solving Therapy (PST), Enhanced Usual Care
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- The University of Texas Health Science Center, Houston
Colorectal Disorders
Intra-Corporeal Anastomosis Result in Quicker Return of Bowel Function/Earlier Discharge
Adult patients who are regularly scheduled to undergo a right hemicolectomy via a minimally invasive approach (robotic or laparoscopic) with the creation of an anastomosis.
- Trial name
- RICART (NCT03862781)
- Testing
- Right Hemicolectomy
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Corewell Health West
Geriatric Population, Cognitive Ability
The Cognitive-Functional Relationship in Geriatric Hand-Forearm Injuries
Considering the complex structure of hand-forearm injuries and the long rehabilitation process, it is important to investigate factors associated with recovery in geriatric individuals.
- Conditions
- Geriatric Population, Cognitive Ability, Functional Abilities, Hand Injuries
- Trial name
- NCT07379229
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Pamukkale University
Anti-NMDA (N-Methyl D-Aspartate) Receptor Encephalitis
Predicting Functional Outcome and Response to Therapy of Anti-NMDAR Encephalitis at Diagnosis
The goal of this international cohort study is to develop a prediction model for long-term outcome and response to first-line immunotherapy of anti-NMDAR Encephalitis, already at the moment of diagnosis.
- Trial name
- NEOSII (NCT06023160)
- Where
- Netherlands
- Volunteers
- 714 people
- Sponsor
- Erasmus Medical Center
Prostate Cancer, Metastatic Prostate Cancer
The Effect of a Structured Strength and Endurance Training Program on Quality of Life, Fitness, Blood Parameters and Survival in Prostate Cancer Patients
Prostate cancer is the second most common cancer among men. Many patients experience a significantly reduced quality of life due to either the cancer itself or the side effects of treatment.
- Conditions
- Prostate Cancer, Metastatic Prostate Cancer, Prostate Cancer (Post Prostatectomy), Prostate Cancer Patients Treated by Radiotherapy
- Trial name
- ZMoveMent-1 (NCT07126860)
- Testing
- Structured combined resistance and aerobic training, Standard of Care
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Reflux, Gastroesophageal Reflux Disease (GERD)
RESULT (REflux Surgery in Lung Transplantation) Preliminary Study Protocol
The purpose of the prospective study is to collect information surrounding lung transplant in order to develop a randomized study to determine if prevention of gastroesophageal reflux disease (GERD) related aspiration (stomach…
- Trial name
- RESULT (NCT01406210)
- Where
- 4 sites in United States, Canada
- Volunteers
- 647 people
- Sponsor
- Duke University
Ankle Fractures
Ankle Fracture vs Ankle Fracture-Dislocation
The purpose of this study is to compare outcomes of patients with an ankle fracture to those with ankle fracture-dislocations. We hypothesize that long-term clinical outcomes for patients sustaining ankle fracture dislocations…
- Trial name
- NCT02198768
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Schizophrenia
Brain Image Markers Associated With Cognitive Training and Aerobic Exercise in Schizophrenia
This study evaluates the brain correlates of Cognitive Training and Aerobic Exercise in schizophrenia. A third of participants will receive Cognitive Training plus Standard Care for schizophrenia.
- Trial name
- CORTEX-SP (NCT03509597)
- Testing
- Aerobic Exercise, Cognitive Training, Treatment as usual
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Red Salud Mental Araba