Clinical trials: Functional Outcomes
Rectal Cancer, Surgery
Assessment of Functional Digestive and Genitourinary Outcomes in Patients With Rectal Cancer.
Total mesorectal excision and neoadjuvant radio-chemotherapy have revolutionized the management of rectal cancer allowing an increase in survival (between 55 and 68% at 5 years) and allowing a decrease of local recurrence (under…
- Trial name
- Rectqol (NCT03459235)
- Testing
- quality of life
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Caen
Renal Cell Carcinoma (Kidney Cancer)
Patient Reported Outcomes and Different Renal Artery Clamping Techniques During Robot Assisted Kidney Resection
The target population for this study consists of all patients undergoing kidney surgery at Haukeland University Hospital, Norway, with the primary focus being patients undergoing robot-assisted partial nephrectomy.
- Trial name
- RAPTOR (NCT07853001)
- Testing
- Standard clamping strategy, Early declamping strategy
- Where
- Norway
- Volunteers
- 130 people
- Sponsor
- Bjarte Almas
Cervical Radiculopathy
To Investigate the Effect of Modified Cawthorne-cooksey Exercises on Cervical Proprioception and Functional Outcomes in Patients With Cervical Radiculopathy. Fifty Four Patients With Cervical Radiculopathy From Both Sexes Will be Selected Randomly and Allocated Into Two Equal Groups.
To investigate the effect of cawthorne-cooksey exercises on cervical proprioception and functional outcomes in patients with cervical radiculopathy
- Trial name
- Cawthorne (NCT07323992)
- Testing
- Cawthorne-Cooksey exercises, Therapeutic Ultrasound
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- German International University
Brain Neoplasm, Metastatic Malignant Neoplasm in the Brain
Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors
This pilot clinical trial studies how well electrocorticography works in mapping functional brain areas during surgery in patients with brain tumors.
- Conditions
- Brain Neoplasm, Metastatic Malignant Neoplasm in the Brain, Recurrent Brain Neoplasm
- Trial name
- NCT02754544
- Testing
- Direct Electrocortical Stimulation, Electrocorticography
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- M.D. Anderson Cancer Center
Maternal Psychological Distress, Prenatal Stress
Roo Study on Mom and Baby Well-Being
This study employs a randomized controlled trial of an established intervention, Mindfulness Based Cognitive Therapy (MBCT) adapted for pregnancy, to examine effects on various aspects of maternal psychological stress during…
- Conditions
- Maternal Psychological Distress, Prenatal Stress, Infant Development, Functional Neuroimaging
- Trial name
- NCT03809598
- Testing
- Mindfulness Based Cognitive Therapy
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Extracorporeal Membrane Oxygenation, Extracorporeal Membrane Oxygenation Complication
PREdiCtIon of Weanability, Survival and Functional outcomEs After ECLS
Extracorporeal life support (ECLS) is used as a last resort intervention in patients with severe cardiac, circulatory and/or respiratory failure with high (>80%) expected mortality.
- Trial name
- PRECISE - ECLS (NCT05444764)
- Where
- 6 sites in Netherlands
- Volunteers
- 800 people
- Sponsor
- UMC Utrecht
Knee Osteoarthritis (OA)
Instrument-Assisted Soft Tissue Mobilization as an Adjunct to Therapeutic Exercises in Individuals With Knee Osteoarthritis
To determine the efficacy of IASTM as an adjunct to therapeutic exercises on pain, range of motion, and functional performance in individuals with knee OA.
- Trial name
- NCT07710209
- Testing
- IATSM, Therapeutic Exercise
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Foundation of Medical Research and Laboratories, Pakistan
COVID-19, Coronavirus Infections
Functional Outcomes in COVID-19 Survivors and Use of a Digital Platform for Rehabilitation
COVID-19, an acute respiratory disease caused by coronavirus-2 (SARS-CoV-2), and in most cases, causes mild to moderate symptoms of fever, cough and dyspnea.
- Conditions
- COVID-19, Coronavirus Infections, Exercise Therapy
- Trial name
- NCT04695301
- Testing
- Rehabilitation protocol through a digital platform
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Hospital Israelita Albert Einstein
Left Branch Bundle Block, RV - Right Ventricular Abnormality
Functional Outcomes in CondUction System Pacing and Right Ventricular Synchrony (FOCUS-Right)
The goal of this prospective single center clinical trial is to evaluate the safety and feasibility of performing simultaneous exercise stress cardiac magnetic resonance (CPET-CMR) and cardiopulmonary exercise testing in patients…
- Trial name
- FOCUS-Right (NCT06601322)
- Testing
- Pacemaker Interrogation and Electrocardiogram (ECG):, Cardiopulmonary Exercise Test (CPET) and Exercise Stress Cardiac Magnetic Resonance (ExeCMR, Continuous pacemaker telemetry (CPT)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Virginia Commonwealth University
Peripheral Nerve Injury Upper Limb
BMAC Nerve Allograft Study
This study is a prospective, multi-center, proof of principle, phase I human safety study evaluating the sequential treatments of the Avance Nerve Graft, a commercially available decellularized processed peripheral nerve…
- Trial name
- NCT03964129
- Testing
- Avance Nerve Graft with Autologous BMAC
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- Brooke Army Medical Center
Kidney Transplant
Study Comparing Sirolimus With Cyclosporine in a Calcineurin Inhibitor (CNI)-Free Regimen in Kidney Transplant Recipients
The purpose of this study is to determine if one drug is superior to another with regard to safety and the preservation of renal function after a kidney transplant.
- Trial name
- NCT00137345
- Testing
- sirolimus
- Where
- 82 sites in United States, Argentina and 19 more
- Volunteers
- 500 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Lung Cancer
Effect of Pulmonary Rehabilitation on Surgical Outcomes in the Cancer Setting
The goal of this clinical research study is to see if pulmonary rehabilitation can improve patients' lung function, which would increase their chances of becoming eligible for surgery.
- Trial name
- NCT00618553
- Testing
- Questionnaire, Pulmonary Rehabilitation
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- M.D. Anderson Cancer Center
Heart Failure With Preserved Ejection Fraction, Heart Failure With Reduced Ejection Fraction
Home-Based Cardiac Rehabilitation for Patients With Heart Failure
The vast majority of individuals with heart failure do not participate in center based cardiac rehabilitation (CBCR). While steps to increase utilization of CBCR are important, many individuals will still not participate for a…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Heart Failure With Reduced Ejection Fraction, Cardiovascular Diseases
- Trial name
- MOBILE HEART (NCT06479876)
- Testing
- HBCR
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Knee Osteoarthritis
Efficacy of High Power Laser Versus Low Level Laser in Ultrasonographic and Functional Outcomes in Patients With Knee Osteoarthritis
this study will be conducted to compare between high power laser and low-intensity laser on ultrasonographic and functional outcomes in patients with knee osteoarthritis
- Trial name
- OA (NCT06419569)
- Testing
- high power laser, low level laser, conventional physical therapy
- Volunteers
- 90 people
- Sponsor
- Cairo University
Preeclampsia, Hypertensive Disorder of Pregnancy
Multiparametric Assessment of Maternal Vascular Function in the Prediction of Hypertensive Disorders of Pregnancy
The present study is a single-centre prospective study that will enrol pregnant women during their first trimester of pregnancy (11+0 - 13+6 weeks of gestation).
- Trial name
- EDIPE (NCT05999851)
- Testing
- Arterial applanation tonometry, In vivo endothelial glycocalyx measurement, Serum markers of angiogenesis and endothelial dysfunction
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Orthopaedic Disorders, Neck of Femur Fracture
Effects of Individualized Physical Therapy and Group Physical Therapy on Functional Outcomes in Patients With Femoral Neck Fracture in Gaza Strip
The research explores how individualized, one-on-one physical therapy programs versus group-based therapy sessions influence recovery in terms of functional mobility, pain reduction, muscle strength, balance, and overall quality…
- Trial name
- neck of femure (NCT07168070)
- Testing
- physical therapy and exercise, group physical therapy vs individualized physical therapy, Group Physical therapy
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University - Gaza
Coronary Artery Disease, CABG
Clinimetric Properties of Performance Based Functional Outcome Measure After (CABG) Surgery
The purpose of this research is to determine which performance based functional outcome test among Time up and go test, Five times sit to stand test, 2 minute walk test and 6 minute walk test has the greatest significance in…
- Trial name
- NCT07060937
- Testing
- Physiotherapy Protocol
- Where
- 2 sites in Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Effect of Different Dosing Regimens of Tadalafil or Tamsulosin Combined With 5α-Reductase Inhibitors on Urinary and Sexual Outcomes in Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a common condition among aging men that causes lower urinary tract symptoms (LUTS) and may negatively affect sexual function.
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms, Erectile Dysfunction
- Trial name
- DTT-BPH (NCT07715448)
- Testing
- Tamsulosin, Tadalafil, 5-Alpha Reductase Inhibitor
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Beni-Suef University
Fibromyalgia
Comparison of Muscle Energy Techniques and Breathing Exercises for Functional Improvement in Fibromyalgia
This study is planned to compare the effects of Muscle Energy Techniques (MET) with breathing exercises for improving functional outcomes in patients with fibromyalgia. A randomized controlled trial will be conducted.
- Trial name
- MET (NCT04674878)
- Testing
- METs, Breathing exercise group
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Soft Tissue Sarcoma of the Lower Extremity, Bone Tumor of the Lower Extremity
Prehabilitation in Childhood Soft Tissue or Bone Sarcomas
This study aims to investigate the feasibility of a prehabilitative training intervention. The intervention includes specific strength and balance exercises during neoadjuvant chemotherapy with children and adolescents diagnosed…
- Conditions
- Soft Tissue Sarcoma of the Lower Extremity, Bone Tumor of the Lower Extremity, Childhood and Adolescent Cancer
- Trial name
- Prehab4Kids (NCT06743958)
- Testing
- Exercise intervention
- Where
- 2 sites in Germany
- Volunteers
- 16 people
- Sponsor
- Technical University of Munich
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