Clinical trials: Functional Outcomes
Arthropathy, Osteoarthritis, Hip
Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty
The aim of this study is to compare the effectiveness of Virtual Reality therapy (VR therapy), Non-Sleep Deep Rest relaxation (NSDR relaxation) each delivered as an adjunct to standard postoperative rehabilitation, in older…
- Conditions
- Arthropathy, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT07386561
- Testing
- Immersive Virtual Reality Therapy, Non-Sleep Deep Rest Relaxation, Conventional rehabilitation
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Renal Insufficiency,Chronic, Dietary Intake Patterns
Strategies for Proactive Health in People With Kidney Function Decline
This prospective cohort study aims to investigate how kidney function decline affects multiple body systems and how personalized nutrition can help maintain health and slow disease progression.
- Conditions
- Renal Insufficiency,Chronic, Dietary Intake Patterns, Malnutrition, Frailty
- Trial name
- NCT07245186
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Huashan Hospital
Chronic Sinusitis, Postoperative Pain
Opioid-Free Anesthesia in FESS: A Prospective ERAS Study
1. Information for Patients and Families What is this study about? When patients undergo functional endoscopic sinus surgery (FESS), strong pain relievers called opioids are traditionally used during anesthesia.
- Conditions
- Chronic Sinusitis, Postoperative Pain, Postoperative Nausea and Vomiting (PONV), Surgical Field Visibility
- Trial name
- OFA-FESS (NCT07812389)
- Testing
- Dexmedetomidine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Filiz Kaya
Crohn Disease (CD), Dynamic Prediction Model
Development of a Dynamic Prediction Model for Crohn's Disease-Related Intestinal Surgery Using Longitudinal Indices of Routine Blood Tests: A Single-Center Retrospective Cohort Study
This single-center retrospective cohort study aims to develop and internally validate a dynamic prediction model that uses longitudinal data from routinely collected blood tests to continuously assess the risk of Crohn's disease…
- Trial name
- NCT07644390
- Volunteers
- 500 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Social Anxiety Disorder
Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social Anxiety
The purpose of this clinical trial is to answer the question: can the investigators predict which adults with social anxiety disorder (SAD) will successfully respond to treatment? To answer this question, the investigators plan…
- Trial name
- NCT05683223
- Testing
- Group CBT for Social Anxiety Disorder, Sertraline, Individual CBT for Social Anxiety Disorder
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Lumbosacral Radiculopathy
Augmented Posterior Oblique Sling Activation on Lumbopelvic Recruitment Pattern in Lumbosacral Radiculopathy
The current study aims to determine the impact of augmented posterior oblique sling activation on lumbopelvic recruitment pattern and functional outcomes in patients with unilateral lumbosacral radiculopathy.
- Trial name
- NCT06558383
- Testing
- augmented posterior oblique sling activation, selected physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Bone Lengthening, Gait Disorders
Video Feedback-Supported Rehabilitation After Bilateral Femoral Lengthening
This randomized controlled study aims to investigate the effects of adding video feedback-supported gait training to a standard rehabilitation program in individuals undergoing cosmetic bilateral femoral lengthening surgery.
- Trial name
- NCT07731022
- Testing
- Video Feedback-Supported Gait Training, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Stroke
Effects of Intensive Robot-assisted Therapy in Patients With Subacute Stroke
Robot-assisted training (RT) devices developed to date have a significant impact on stroke rehabilitation. Several research groups have developed the robotic devices and examined their efficacy on improving upper limb function…
- Trial name
- RT (NCT01767480)
- Testing
- RT, Conventional rehabilitation (CR)
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Chronic Stroke
Differential Effectiveness of Robotic Assisted Therapy on Upper Extremity Function in Patients With Chronic Stroke
The objectives of this study are to: determine the effects of exoskeleton vs. end effector training systems on upper extremity motor and physiological function, daily functions, quality of life and self-efficacy in patients with…
- Trial name
- NCT04260061
- Testing
- training systems
- Where
- Taiwan
- Sponsor
- Chang Gung Memorial Hospital
Cerebrovascular Accident
Effects and Mechanisms of Treatment Intensity of Mirror Therapy in Patients With Subacute Stroke
The purpose of this study will evaluate the long-term benefits, optimal dose and mechanisms of mirror therapy and its effects on physiological markers.
- Trial name
- NCT01655160
- Testing
- MT with low-intensity group (MT-LI), MT with moderate-intensity group, Mirror therapy with high intensity group
- Where
- Taiwan
- Volunteers
- 2 people
- Sponsor
- Chang Gung Memorial Hospital
Hepatitis C, Alcohol Use Disorder
HCV and Co-morbid Alcohol Use Disorders: A Translational Investigation of Antiviral Therapy Outcomes on CNS Function
The primary objective of this research project is to compare neuropsychiatric functioning, cortical activity, white matter integrity, and immune response among Veterans with and without alcohol use disorder (AUD), before and…
- Trial name
- NCT03902366
- Testing
- Neuropsychological assessment, Neuroimaging
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cervical Adenocarcinoma, Hysterectomy
Effect of Prehabilitation on Recovery Outcomes in Post-Surgical Cervical Cancer Women
This parallel-group randomized controlled trial evaluated the effectiveness of a four-week multimodal prehabilitation programme on pelvic function and quality of life among women with cervical cancer undergoing radical…
- Conditions
- Cervical Adenocarcinoma, Hysterectomy, Cervical Cancer
- Trial name
- PROP-CC (NCT07398313)
- Testing
- Structured Prehabilitation Protocol, Conventional
- Where
- India
- Volunteers
- 34 people
- Sponsor
- Saveetha University
Femoral Neck Fractures, Hip Fractures
Clinical and Functional Outcomes of Lateral vs Posterior Hemiarthroplasty
This prospective, single-center, randomized clinical trial compared the clinical and functional outcomes of hemiarthroplasty performed via lateral versus posterior surgical approaches in elderly patients with displaced…
- Conditions
- Femoral Neck Fractures, Hip Fractures, Hemiarthroplasty
- Trial name
- NCT07345182
- Testing
- Posterior approach hemiarthroplasty, Lateral approach hemiarthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people
- Sponsor
- Umraniye Education and Research Hospital
Myocardial Infarction, Death
Association of Endothelial Function and Clinical Outcomes in Subjects Admitted to Chest Pain Unit
It is recognized that endothelial dysfunction is a major factor contributing to the atherogenic process. Abnormal function of the endothelium is detectable prior to obvious intimal lesions in patients with risk factors for…
- Conditions
- Myocardial Infarction, Death, Cerebrovascular Accident, Congestive Heart Failure
- Trial name
- NCT01618123
- Where
- 2 sites in United States, Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Critical Illness, Enteral Nutrition
Trial of Enteral Glutamine on Clinical Outcomes in Critically Ill Patients
Glutamine supplementation has beneficial effects on morbidity and mortality in critically ill patients, possibly in part through an attenuation of the proinflammatory cytokine response and a Immune function.
- Conditions
- Critical Illness, Enteral Nutrition, Multiple Organ Failure, Infection Complication
- Trial name
- NCT02998931
- Testing
- Glutamin, Maltodextrin
- Where
- 2 sites in Iran
- Volunteers
- 200 people
- Sponsor
- Shahid Beheshti University
Multiple Sclerosis, Exercise
Impact of Exercise Training on Serum Glial Fibrillary Acidic Protein (GFAP), Brain Volumetry, and Functional Outcomes in Multiple Sclerosis
This single-blind, randomized controlled trial will employ a two-arm parallel design (exercise group vs. control group) with a 12-week intervention period.
- Conditions
- Multiple Sclerosis, Exercise, Function
- Trial name
- NCT07521995
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Firat University
Lung Cancer
Effect of Pulmonary Rehabilitation on Surgical Outcomes in the Cancer Setting
The goal of this clinical research study is to see if pulmonary rehabilitation can improve patients' lung function, which would increase their chances of becoming eligible for surgery.
- Trial name
- NCT00618553
- Testing
- Questionnaire, Pulmonary Rehabilitation
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- M.D. Anderson Cancer Center
Sanfilippo Syndrome, Mucopolysaccharidosis III
Study of Cannabidiol in Sanfilippo Syndrome
The goal of this clinical trial is to test cannabidiol in Sanfilippo syndrome. The main questions it aims to answer are: 1) determine the safety of cannabidiol in Sanfilippo syndrome, and 2) explore the efficacy of cannabidiol in…
- Trial name
- NCT06333041
- Testing
- Epidiolex
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Brain Injuries, Traumatic, Cerebrovascular Trauma
A Multidimensional Inpatient Balance Training Class to Improve Functional Outcomes in Rehabilitation Inpatients With ABI
Many survivors of acquired brain injury (ABI) suffer from decreased balance and increased risks of falls. Previous studies indicate that balance training improves balance, reduces falls, and increases walking speed and balance…
- Conditions
- Brain Injuries, Traumatic, Cerebrovascular Trauma, Acute Brain Injuries
- Trial name
- NCT03110237
- Testing
- Control Balance Training (BT) class, Fallproof Balance Training (BT) class
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Advanced Malignant Neoplasm
Enhancing Connections Program in Improving Family Adjustment in Patients With Incurable Cancer
This pilot clinical trial studies how well the Enhancing Connections program improves family adjustment in patients with incurable cancer.
- Trial name
- NCT03049397
- Testing
- Communication Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
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