Clinical trials: Functional Outcomes
Dementia, Cognition
Cognitive and Functional Status and Dialysis Outcomes in Older Hemodialysis Patients
The purpose of this study is to estimate how quickly cognitive status and functional status in older patients on hemodialysis declines.
- Conditions
- Dementia, Cognition, End-stage Renal Disease
- Trial name
- NCT00739843
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Chicago
Tongue Cancer
Normative Ranges of Lingual Strength and Endurance and the Impact of the IOPI Lingual Strength Trainer on Quantitative Functional Outcomes and Patient-Reported Outcomes After Partial Glossectomy or Hemiglossectomy for Oral Tongue Cancer, An Unblinded: Randomized Pilot Study
The purpose of this study is to learn more about tongue strength and endurance by using the Iowa Oral Performance Instrument (IOPI). The IOPI is a device that measures tongue pressure.
- Trial name
- NCT07124520
- Testing
- Iowa Oral Performance Instrument (IOPI)
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Tongue Carcinoma
Improving Therapeutic Outcomes in the Tongue Carcinoma Patient: Assessment of Adaptation Using Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging
The purpose of this study is to see how the brain re-learns to control the tongue in speaking and swallowing when either portions of the tongue have been removed, or when the tongue has been treated with radiation, in order to…
- Trial name
- NCT00594724
- Testing
- MRI
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Interstitial Lung Diseases
The Effects of Whole-Body Vibration Training on Clinical and Functional Outcomes in Individuals Diagnosed With Interstitial Lung Disease
This randomized controlled trial aims to investigate the clinical and functional effects of Whole Body Vibration (WBV) training when added to a standard pulmonary rehabilitation (PR) program in patients with fibrotic interstitial…
- Trial name
- NCT07709260
- Testing
- Inspiratory Muscle Training, Peripheral Muscle Strengthening Exercises, Aerobic Exercise Training (Cycle Ergometer)
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Istinye University
Renal Cell Carcinoma (Kidney Cancer)
Patient Reported Outcomes and Different Renal Artery Clamping Techniques During Robot Assisted Kidney Resection
The target population for this study consists of all patients undergoing kidney surgery at Haukeland University Hospital, Norway, with the primary focus being patients undergoing robot-assisted partial nephrectomy.
- Trial name
- RAPTOR (NCT07853001)
- Testing
- Standard clamping strategy, Early declamping strategy
- Where
- Norway
- Volunteers
- 130 people
- Sponsor
- Bjarte Almas
Aging, Aging Well
100-Year Human Aging Study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo…
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality
- Trial name
- NCT07563777
- Testing
- Comprehensive Multi-System Clinical Screening
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Iliopsoas Syndrome, Eccentric Exercise Training
Eccentric Biased Exercises Effect on Functional Outcomes in Iliopsoas Tendonitis
Hip and pelvis injuries represent 2-5% of all injuries. Among these injuries, groin pain is the most common finding. The most common injuries in the hip, pelvis, and thigh area are musculotendinous, (eg, quadriceps strain…
- Trial name
- NCT07426601
- Testing
- ECCENTRIC BIASED EXERCISES FOR ILIOPSOAS TENDONITIS
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Symptomatic Neuroma, Phantom Limb Pain After Amputation
Evaluation of RPNI for Symptomatic Neuromas in Lower Limb Amputees
This prospective, observational cohort study evaluates the long-term outcomes of Regenerative Peripheral Nerve Interface (RPNI) surgery in patients with major lower extremity amputations suffering from symptomatic neuromas.
- Conditions
- Symptomatic Neuroma, Phantom Limb Pain After Amputation, Residual Limb Pain, Neuropathic Pain
- Trial name
- RPNI-AMPUTEE (NCT07420192)
- Testing
- Regenerative Peripheral Nerve Interface (RPNI) Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Saglik Bilimleri Universitesi
Low Back Pain, Chronic
Comparative Effects of Group Based Exercises with and Without Cognitive Functional Therapy on Clinical Outcomes in Patients with Chronic Low Back Pain
1.1Research objective The objective of the study is to find the comparative effects of group based exercises with and without cognitive functional therapy on clinical outcomes in patients with chronic low back? 1.2 Hypothesis…
- Trial name
- NCT06759675
- Testing
- group based exercise with Cognitive functional therapy, Group based exercise
- Volunteers
- 40 people
- Sponsor
- University of Faisalabad
Dental Crowns, Orthodontics, Interceptive
Clinical Outcomes of Functional Space Maintainers Designed Using CAD/CAM Technology in Early Loss of the First Primary Molar
As passive fixed space maintainers do not replace the lost tooth and therefore do not provide a chewing function, this study aims to evaluate the efficiency of an innovative solution for maintaining space after the premature…
- Conditions
- Dental Crowns, Orthodontics, Interceptive, Orthodontic Appliance
- Trial name
- KOS&MET (NCT06744153)
- Testing
- Space Maintainer
- Where
- Serbia
- Volunteers
- 28 people
- Sponsor
- Rasa Mladenovic
Remote Monitoring of Pain and Recovery Quality in the Immediate Postoperative Period Using a Digital Health Tool, Pain, Postoperative
Remote Assessment of Pain and Recovery Quality After Surgery Using a Digital Form: A Pilot Study
After surgery, doctors need to know how patients are doing, especially in the first hours after they leave the recovery room. This can be hard to track once patients go to a regular hospital room, and some symptoms - like pain or…
- Conditions
- Remote Monitoring of Pain and Recovery Quality in the Immediate Postoperative Period Using a Digital Health Tool, Pain, Postoperative, Postoperative Nausea and Vomiting, Recovery of Function (G11.427.698.620)
- Trial name
- NCT07794267
- Testing
- Digital web-based postoperative follow-up form
- Where
- Brazil
- Volunteers
- 213 people
- Sponsor
- Hospital de Base
Schizophrenia, Schizoaffective Disorder
Add-on HD Hf-tRNS Over Bilateral DLPFC for Treating Patients With Schizophrenia
The study aimed to investigate the effects of high-definition transcranial random noise stimulation over bilateral prefrontal cortex on psychopathological symptoms, other clinical outcomes, autonomic functioning ,and brain…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Psychotic Symptoms, Neurocognitive Dysfunction
- Trial name
- NCT04038788
- Testing
- HD hf-tRNS
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Knee Osteoarthritis
Effectiveness of Exercise Plus Pain Neuroscience Education on Brain Function in Knee Osteoarthritis
A three-arm randomized controlled trial will be conducted. Fifty-nine participants with KOA will be recruited in a 1:1:1 ratio. Assessor, and statistician will be blinded to group allocation.
- Trial name
- NCT06482970
- Testing
- Neuromuscular exercise plus pain neuroscience education, Neuromuscular exercise
- Volunteers
- 57 people
- Sponsor
- Universidad Santo Tomas, Chile
Lumbar Spine Injury, Spinal Fusion
Does Prehabilitation Improve Outcomes in Patients Undergoing Complex Spine Fusion Surgery?
A novel prehabilitation method has been implemented at our institution to decrease perioperative outcome complications for frail complex spine fusion surgery patients.
- Conditions
- Lumbar Spine Injury, Spinal Fusion, Frailty, Prehabilitation
- Trial name
- NCT05034341
- Testing
- Multimodal Prehabilitation, Standard Pre-Surgical Clinical Care
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Florida
Left Branch Bundle Block, RV - Right Ventricular Abnormality
Functional Outcomes in CondUction System Pacing and Right Ventricular Synchrony (FOCUS-Right)
The goal of this prospective single center clinical trial is to evaluate the safety and feasibility of performing simultaneous exercise stress cardiac magnetic resonance (CPET-CMR) and cardiopulmonary exercise testing in patients…
- Trial name
- FOCUS-Right (NCT06601322)
- Testing
- Pacemaker Interrogation and Electrocardiogram (ECG):, Cardiopulmonary Exercise Test (CPET) and Exercise Stress Cardiac Magnetic Resonance (ExeCMR, Continuous pacemaker telemetry (CPT)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Virginia Commonwealth University
Constipation - Functional, Refractory Constipation
Predicting Treatment Outcomes in Refractory Constipation Through Brain Connectivity Evaluation
The goal of this observational study is to identify the characteristics of brain functional connectivity in refractory constipation and fluoxetine-sensitive patients.
- Conditions
- Constipation - Functional, Refractory Constipation, Fluoxetine, fMRI
- Trial name
- NCT06221722
- Testing
- BOLD-fMRI, Regular treatment of functional constipation, fluoxetine
- Where
- 3 sites in China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Diabetic Foot Ulcer
Custom Insole With Transcutaneous Electrical Nerve Stimulation on Clinical Outcomes of Diabetic Foot Ulcers
Diabetic foot ulcers (DFUs) are one of the serious complications of diabetes, typically resulting from neuropathy or peripheral arterial disease, and can often lead to amputation.
- Trial name
- NCT07109895
- Testing
- Standard Care Only, Custom Insole + Standard Care, TENS + Custom Insole + Standard Care
- Where
- Pakistan
- Volunteers
- 159 people
- Sponsor
- University of Lahore
Humeral Fractures, Proximal
Determinants of Function and Clinically Important Outcomes in Proximal Humerus Fractures
The proposed project will be a multi-centre, prospective observational study to determine the prognosis and determinants of functional outcomes of patients with proximal humerus fractures.
- Trial name
- NCT02212600
- Testing
- Observational
- Where
- 2 sites in Canada
- Volunteers
- 500 people
- Sponsor
- London Health Sciences Centre
Chronic Kidney Disease, Peritoneal Dialysis Access
Improving Outcomes in Peritoneal Dialysis
The objective is to understand the best way to place Peritoneal Dialysis (PD) catheters, and the best way to collect data regarding their function in England, Wales and Northern Ireland.
- Trial name
- NCT02207751
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Joint Health
A Decentralized Clinical Study Evaluating the Effectiveness of Two Different Doses of MyCondro™ on Physical Mobility and Joint Health
This study evaluates the effect of two different doses of a consumer-grade product, MyCondro™, on individuals experiencing mobility issues related to knee osteoarthritis.
- Trial name
- NCT07493239
- Testing
- MyCondro 300mg, MyCondro 600mg
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Lesaffre International
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.