Clinical trials: Functional Performance Limitation
Charcot Marie Tooth Disease (CMT), Pes Cavovarus
Walking Function Outcomes Following Surgical Correction With Rehabilitation Versus Physical Therapy Alone in Charcot-Marie-Tooth Disease: A Bidirectional Cohort Study
The goal of this study is to compare changes in walking ability in people with Charcot-Marie-Tooth disease (CMT) who receive two different treatment approaches for foot deformities that affect walking.
- Conditions
- Charcot Marie Tooth Disease (CMT), Pes Cavovarus, Surgery, Exercise Training
- Trial name
- CMT-WALK (NCT07432035)
- Testing
- Functional Surgery plus Rehabilitation, Physical Exercise
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Healthy Individuals
Effects of Exercises Combined With Blood Flow Restriction in Healthy Individuals
Purpose of the study is; to investigate the effect of exercises combined with blood flow restriction on strength, proprioception and functional motor performance in healthy individuals.
- Trial name
- NCT03401567
- Testing
- Exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Pediatric Burns, Burn Injury
Plyometrics for Strength and Function After Pediatric Burns
Pediatric burn survivors may experience persistent deficits in lower-limb strength, explosive power, and functional performance after hospital discharge.
- Conditions
- Pediatric Burns, Burn Injury, Post-Burn Rehabilitation, Rehabilitation
- Trial name
- NCT07590557
- Testing
- Plyometric Training, Standard Exercise Program
- Where
- Saudi Arabia
- Volunteers
- 62 people
- Sponsor
- Qassim University
Healthy Individuals
Acute Effects of Exercises Combined With Blood Flow Restriction in Healthy Individuals
Purpose of the study is; to investigate the acute effects of exercises combined with blood flow restriction on strength, proprioception and functional motor performance in healthy individuals.
- Trial name
- NCT04206345
- Testing
- exercise with blood flow restriction, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Caloric Restriction, Body Composition
Short Term Effects of Semaglutide on Body Composition and Performance
Semaglutide, a GLP-1 receptor agonist, has demonstrated significant weight-loss effects in people with obesity and/or type 2 diabetes, but its impact on exercise performance among lean, fit athletes remains unknown.
- Conditions
- Caloric Restriction, Body Composition, Performance
- Trial name
- NCT07874971
- Testing
- Semaglutide (SEMA)
- Where
- Denmark
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Muscle Strength, Athletic Performance
Nordic vs Blood Flow Restriction Nordic Exercise in Elite Female Pole Vaulters
The purpose of this randomized controlled trial is to compare the effects of Nordic Hamstring Exercise (NHE) and Blood Flow Restriction-assisted Nordic Hamstring Exercise (BFR-NHE) on hamstring muscle strength, muscle morphology…
- Conditions
- Muscle Strength, Athletic Performance, Hamstring Adaptation, Sports Injury Prevention
- Trial name
- NCT07705698
- Testing
- Nordic Hamstring Exercise, Blood Flow Restriction-Assisted Nordic Hamstring Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Toros University
Neuromuscular Function, Athletic Performance Enhancement
Effects of Blood Flow Restriction Training on Neuromuscular Function and Performance in Artistic Jump Rope Athletes
The goal of this randomized controlled trial is to investigate whether blood flow restriction training can improve physical function and sports performance in artistic jump rope athletes.
- Trial name
- NCT07750977
- Testing
- Blood Flow Restriction Training, Conventional Artistic Jump Rope Training
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Sport
Mobility Limitations, Aging
A Comparison of Weighted Vest Exercise and Strength Training
The purpose of this study is to evaluate two types of exercise therapy designed to improve muscle power and mobility: weighted vest exercise vs. progressive resistance training.
- Trial name
- NCT00158119
- Testing
- InVEST (Increased Velocity Exercise Specific to Task)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- National Institute on Aging (NIA)
Athletic Performance Enhancement
Effects of Blood Flow Restriction Training on Physical Function, Muscle Adaptations, and Performance in Roller Skaters
This randomized controlled trial evaluates the effects of adding blood flow restriction training to regular roller skating training on neuromuscular function under non-fatigued and fatigued conditions, muscle morphology, body…
- Trial name
- NCT07736157
- Testing
- Blood Flow Restriction Roller Skating Training, Standardized Roller Skating Training
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Sport
Stroke, "Rehabilitation"
Determinants and Practical Significance of Change in Motor Ability, Functional Performance, and HRQOL After Stroke
This study has two purposes. First, the investigators will identify determinants of changes in motor ability, activities of daily living, and HRQOL after distributed Constraint-induced therapy for patients with stroke with the…
- Trial name
- NCT00776386
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Exercise Training, Blood Flow Restriction Training
Blood Flow Rextriction Training in Upper Extremity of Elderly
Our study aims to decrease independence by increasing upper extremity strength and performance by applying blood flow restrictive training, which has entered the literature as a new method, to the upper extremity in the elderly.
- Conditions
- Exercise Training, Blood Flow Restriction Training, Geriatrics
- Trial name
- NCT05803733
- Testing
- Blood flow restriction (BFR) with low load resistance training, Routine strength training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Infection With Coronavirus SARS-CoV2
Long Term Physical Functional Limitations in Daily Living in SARS-CoV2 Infected Patients Hospitalized in the Acute Phase Then Requiring Rehabilitation
Infection with coronavirus SARS-CoV2 (COVID-19 disease) is unique with its speed of propagation, structural medical reorganizations and length of stay in intensive care needed, diversity of the affected population (in particular…
- Trial name
- CAPACoV19 (NCT04356378)
- Testing
- Data record
- Where
- France
- Volunteers
- 149 people
- Sponsor
- CHU de Reims
Caloric Restriction, Body Composition
Long-Term Effects of Semaglutide on Body Composition and Performance in Running
Semaglutide, a GLP-1 receptor agonist, has demonstrated significant weight-loss effects in people with obesity and/or type 2 diabetes, but its impact on exercise performance among lean, fit athletes remains unknown.
- Conditions
- Caloric Restriction, Body Composition, Performance
- Trial name
- NCT07874932
- Testing
- Semaglutide (SEMA)
- Where
- Denmark
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
PHYSIOLOGICAL PHENOMENA, Homeostasis
Truway Whole-Body Digital Twin and Physiologic Resilience Study (TRU-OMNIBODY)
TRU-OMNIBODY is a prospective observational study designed to develop and independently validate a research-only whole-body digital twin.
- Conditions
- PHYSIOLOGICAL PHENOMENA, Homeostasis, Physical Functional Performance, Cardiorespiratory Fitness
- Trial name
- TRU-OMNIBODY (NCT07805044)
- Testing
- Standardized Physiologic Resilience Challenge, Multimodal Whole-Body Physiologic Monitoring, Research-Only Whole-Body Digital Twin Analysis
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Bilateral Spastic Cerebral Palsy, Cerebral Palsy
Effect of Treadmill Gait Training Combined With Conventional Physiotherapy on Gait Performance and Functional Mobility in Children With Bilateral Spastic Cerebral Palsy: A Randomized Controlled Trial
Cerebral palsy is a neurological condition that affects movement, muscle control, and walking ability in children. Children with bilateral spastic cerebral palsy often experience increased muscle stiffness, difficulty with…
- Conditions
- Bilateral Spastic Cerebral Palsy, Cerebral Palsy, Spasticity Due to Cerebral Palsy, Gait Abnormality
- Trial name
- GAIT-CP (NCT07683338)
- Testing
- Treadmill Gait Training, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Syeda Khatoon e Jannat Welfare Foundation
Aging, Walking
Effects of a Powered Lower-Limb Exoskeleton on Walking Performance in Older Adults
The goal of this clinical trial is to learn whether a powered wearable lower-limb exoskeleton can improve walking performance in independently ambulatory older adults aged 65 to 75 years.
- Conditions
- Aging, Walking, Physical Function, Mobility Limitation
- Trial name
- E-WALK (NCT07633093)
- Testing
- Powered Lower-Limb Exoskeleton
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hunan Normal University
Cerebral Palsy
Effects of Forms of Modified CIT on Upper Extremity Performance in Cerebral Palsy
The purpose of this study will employ clinical assessment tools to examine the effects of modified constraint-induced therapy (mCIT) on the more affected upper extremity of children with cerebral palsy.
- Trial name
- NCT01643239
- Testing
- Hospital-based mCIT restraint of the unaffected arm and practice of the affected arm, Hospital-based mCIT, Hospital-based TR
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Hemiparesis
Blood Flow Restriction Training on Upper Limb Performance
Background; Blood flow restriction training (BFRT) is a physical intervention that promotes many beneficial muscular activities and functions when low load/intensity is used in healthy and clinical populations.
- Trial name
- NCT06859905
- Testing
- blood flow restriction training, regular exercises
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- University of Hail
Recovery, Recovery Time
Effect of Blood Flow Restriction on Recovery After Maximal Resistance Exercise
Resistance training has been widely performed due to its health benefits. However, performing this training at high intensity causes significant muscle stress, leading to fatigue and compromising performance.
- Trial name
- NCT07342634
- Testing
- BFR-80%, BFR-60%, BFR-10mmHg
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Paulista University
Acute Mountain Sickness, High Altitude Pulmonary Edema
Sleep and Cerebral Responses to High Altitude
Mechanisms underlying high-altitude intolerance as well as exercise performance limitation in hypoxia still remain to be fully understood.
- Conditions
- Acute Mountain Sickness, High Altitude Pulmonary Edema, High Altitude Cerebral Edema
- Trial name
- VALLOT 2011 (NCT01565603)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble