Clinical trials: Functional Recovery
Knee Osteoarthritis
Comparison of Functional Recovery After Total Knee Arthroplasty Between Low Phase Angle and High Phase Angle Group
The goal of this observational study is to compare the functional outcome of patients with end-stage knee osteoarthritis (OA) before and after total knee arthroplasty based on the phase angle level.
- Trial name
- NCT06701474
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Abdominal Surgery
Development of a Patient-Reported Outcome Measure to Assess Recovery After Abdominal Surgery
As surgery enters the era of value-based care, it is advocated that postoperative recovery be measured using patient-reported outcomes (PROs) as they provide a mean to incorporate the patient's perspectives and experiences into…
- Trial name
- NCT03461497
- Where
- 7 sites in United States, Brazil and 3 more
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Stroke
Effect of a Physiotherapy Protocol for Gait and Functional Recovery After Stroke
The purpose of this study was to identify and evaluate the effect of a new protocol of physiotherapy to retrain walking ability after stroke in subjects older than fifty-five.
- Trial name
- NCT02250040
- Testing
- Conventional physiotherapy, Techniques based on patients' functional level were added.
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- University of Valencia
Hip Fractures
Stronger at Home: Improving Outcomes for Older Adults After Hip Fracture
The goal of this clinical trial is to compare the effectiveness of a new 14-week individually-tailored home-based rehabilitation program called "Stronger at Home" with usual care in improving functional recovery in…
- Trial name
- S@H (NCT05972005)
- Testing
- The Intervention (Stronger at Home Intervention), Usual care (Control)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Dr. Mohammad Auais, PhD
Stroke
Correlation Between Clinical Neurological Biomarkers and Rehabilitation Outcome
Our study purpose is to evaluate the predictive power of various clinical, neurophysiological, and neuroimaging biomarkers-acquired and analyzed using advanced and integrated techniques-on motor functional recovery and disability…
- Trial name
- PREVICTUS (NCT06805929)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS San Raffaele Roma
Postoperative Nausea and Vomiting, Bowel Functions
Menthol Chewing Gum After Laparoscopic Colorectal Surgery
This randomized controlled trial was conducted to evaluate the effect of menthol chewing gum on postoperative nausea and vomiting, bowel function, and recovery in patients undergoing laparoscopic colorectal surgery.
- Conditions
- Postoperative Nausea and Vomiting, Bowel Functions, Postoperative Recovery
- Trial name
- NCT07796529
- Testing
- Menthol Chewing Gum
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sennur Kula Şahin
Cell Migration, Cell Invasion
This Repeated Measures Parallel-group Investigation Will Examine the Influence of Short-term Melatonin Supplementation (5mg, 3 x Day for 72 Hours) on Cellular Responses, Functional Performance and Recovery Following an Acute Bout of Dynamic Resistance Exercise in Resistance Trained Men and Women
Oral Melatonin is a commercially available product available alone and as a constituent in a number of supplements. Previous research suggests that short-term supplementation with oral melatonin may amplify the recovery response…
- Conditions
- Cell Migration, Cell Invasion, Exercise Recovery
- Trial name
- NCT06617351
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Rett Syndrome
Measuring Impact of Computer Gaming on Arm Use in Rett Syndrome
Using a tele-research approach, we will recruit, enroll, guide and support carers and participants to engage in computer based activities (modified virtual reality) with the primary outcome of reducing stereotypies and increasing…
- Trial name
- NCT05012475
- Testing
- Modified Virtual Reality Gaming
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Acromioclavicular Joint Injury, Acromioclavicular Joint Dislocation
Contralateral Resistance Training During Immobilization in Patients With Acromioclavicular Joint Injury
This randomized controlled trial aims to compare the effects of contralateral eccentric and concentric resistance training performed during the immobilization period following acromioclavicular joint injury.
- Trial name
- CROSS-ACD (NCT07628361)
- Testing
- Contralateral Eccentric Resistance Training, Contralateral Concentric Resistance Training
- Where
- Chile
- Volunteers
- 16 people
- Sponsor
- Universidad Nacional Andres Bello
Arthroplasty, Replacement, Knee
Silkeborg Knee Replacement Cohort Study
In this cohort study, we will investigate short and long term outcomes after knee replacement surgery and identify preoperative and early postoperative factors associated with long term outcome.
- Trial name
- NCT03411083
- Testing
- Total or unicompartmental knee replacement
- Where
- Denmark
- Volunteers
- 1,225 people
- Sponsor
- Central Jutland Regional Hospital
Stroke
Transcranial Direct Current Stimulation Combined Sensory Modulation Intervention in Chronic Stroke Patients
Background and purpose: About 30% of people with stroke suffered from severe long-term upper extremity （UE） motor impairment. Severe UE impairment, especially dysfunction of hand, can greatly impact stroke patients' daily living…
- Trial name
- NCT01847157
- Testing
- tDCS, Epidermis anesthesia, Repeated passive movement
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan University Hospital
Repetitive Transcranial Magnetic Stimulation, Stroke
Comparative Effectiveness of Ipsilesional High-frequency rTMS, Contralesional Continuous Burst Theta rTMS, and Sham rTMS, Each Combined With Physiotherapy, in Subacute Ischemic Stroke Upper Limb Recovery : Clinical, Neurophysiological and Radiological
To compare the efficacy of lesional high-frequency rTMS, contralesional cTBS, and sham stimulation in improving motor and cognitive recovery in post-stroke patients undergoing physiotherapy.
- Conditions
- Repetitive Transcranial Magnetic Stimulation, Stroke, Functional MRI
- Trial name
- NCT06799312
- Testing
- Ipsilesional high frequency rTMS combined with physiotherapy, Contralesional Continuous Burst Theta rTMS (cTBS) + Physiotherapy
- Volunteers
- 90 people
- Sponsor
- Assiut University
Elective Valvular Cardiac Surgery
Plasma Biomarkers in Cardiac Valve Surgery
The level of four biomarkers will be measured in the patients' plasma after induction of anaesthesia. There biomarkers are NT-ProBNP, ST2, Galectin-3 and GDF-15.
- Trial name
- NCT02641665
- Testing
- Cardiac valve surgery
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- University of Liege
Muscle Damage, Inflammation
Protein and Recovery From Exercise-induced Muscle Damage
Intense, eccentric resistance exercise causes muscle damage, soreness, inflammation, and a loss of muscle function. Protein-amino acid supplementation before, during, and following damaging resistance exercise may reduce muscle…
- Trial name
- NCT02034721
- Testing
- Protein supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
HIV Infection, Endothelial Dysfunction
RAltegravir Switch STudy: Effects on Endothelial Recovery
Treatment with HIV-infection with protease inhibitors is associated with high blood lipids and higher chance for cardiovascular complications.
- Trial name
- RASSTER (NCT01453933)
- Testing
- raltegravir
- Where
- 2 sites in Netherlands
- Volunteers
- 24 people
- Sponsor
- UMC Utrecht
Stroke
Cortical Reorganization Models for Motor Areas and Inter-hemispheric Equilibrium Post-stroke: a Pilot Study
The main objective is to develop models for the cortical reorganization of motor areas and inter-hemispheric equilibrium in the early phase of post stroke recovery evaluated by the fNIRS technique from day 0 to day 60 (day 0…
- Trial name
- ERASM (NCT02664636)
- Testing
- Physiotherapy, Occupational therapy, Functional near-infrared spectroscopy
- Where
- 2 sites in France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Gastropathy
Gastroplasty and Electrical Impedance Tomography
Worldwide there is a high prevalence of morbid obesity with a progressive increase in incidence in recent years, causing serious consequences for the health services.
- Trial name
- NCT03476863
- Testing
- Alveolar Recruitment Maneuver, Conventional mechanical ventilation
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- Daniella Cunha Brandao
Total Knee Replacement
Innovative Gait Training for People With Knee Osteoarthritis Using Dual Belt Treadmill
Knee osteoarthritis (OA) is the most common form of arthritis and is the leading cause of chronic musculoskeletal pain and functional disability. Gait assessment is essential for the rehabilitation of people with knee OA.
- Trial name
- NCT05958212
- Testing
- Gait training program, Conventional training only
- Where
- Hong Kong
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Peripheral Nerve Injury
Mirror Therapy Combined With Contralaterally Controlled Functional Electrical Stimulation for Peripheral Nerve Injury
The goal of this trial is to evaluate the effects of mirror therapy combined with contralaterally controlled functional electrical stimulation on motor recovery and neuroplasticity in patients with peripheral nerve injury.
- Trial name
- NCT06209632
- Testing
- mirror therapy, contralaterally controlled functional electrical stimulation, conventional physiotherapy
- Where
- Taiwan
- Volunteers
- 7 people
- Sponsor
- National Taiwan University Hospital
OA Knee, TKA
Comparison of Functional Recovery Between Restricted Inverse Kinematic Alignment and Adjusted Mechanical Alignment With Robotic-assisted Unilateral Total Knee Arthroplasty.
The goal of this clinical trial is to learn if restricted inverse kinematic alignment total knee arthroplasty (restricted iKA TKA) improves functional recovery compared to adjusted mechanical alignment total knee arthroplasty…
- Trial name
- NCT06835621
- Testing
- Restricted inverse kinematic alignment Total Knee Arthroplasty, Adjusted Mechanical alignment Total Knee Arthroplasty
- Where
- 2 sites in Thailand
- Volunteers
- 80 people
- Sponsor
- Thammasat University