Clinical trials: GAD
Depression, Obsessive-Compulsive Disorder
Pharmacogenetics in Primary Care Psychotropics
Pragmatic trial of pharmacogenetic testing at the time of prescription for a selective serotonin reuptake inhibitor, tricyclic antidepressant or atypical antipsychotic. Does real time intervention improve patient outcomes?
- Conditions
- Depression, Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
- Trial name
- NCT03232502
- Testing
- Pharmacogenetic testing
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Bipolar Disorder, Panic Disorder
Ziprasidone in Bipolar Disorder With Comorbid Lifetime Panic or Generalized Anxiety Disorder(GAD)
The specific aim of this study is to evaluate the efficacy, tolerability, and safety of ziprasidone monotherapy in comparison to placebo in the treatment of ambulatory bipolar disorder with co-morbid lifetime panic disorder or…
- Conditions
- Bipolar Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- PfizerAnxty (NCT01172652)
- Testing
- Ziprasidone
- Where
- 3 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Posttraumatic Stress Disorder, Major Depressive Disorder
An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Personnel
Public safety personnel (PSP; e.g., border services personnel, correctional workers, firefighters, paramedics, police, public safety communicators) are frequently exposed to potentially psychologically traumatic events.
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05530642
- Testing
- Emotional Resilience Skills Training (ERST)
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Regina
Stress, Generalized Anxiety
Enhancing Health in Rural Populations: Music as Therapy
The goal of this clinical trial is to learn whether a music-based intervention can improve mental and physical health and strengthen coping skills among adults living in residential care settings in northern Arizona.
- Conditions
- Stress, Generalized Anxiety, Chronic Pain, Depression Disorder
- Trial name
- NCT07538427
- Testing
- Music Based Intervention
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Anxiety Disorders
Efficacy Study of Abdominal Massage Therapy to Treat Generalized Anxiety Disorder of Deficiency of Both Heart and Spleen Type
Generalized Anxiety Disorder (GAD) is characterized by the presence of persistent worry or fear of no explicit object and fixed content, or things that might occur in real life，which not corresponds with the realities.
- Trial name
- NCT02186366
- Testing
- Abdominal Massage Therapy, Buspirone
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sun Qing
Depression / Major Depressive Disorder, Anxiety
Digital Single-Session Cognitive Behavioural Therapy in Healthy Adults
The goal of this study is to learn if digital single-session cognitive behavioural therapy can treat mental health in adults. The main question it aims to answer is: Does digital single-session cognitive behavioural therapy…
- Conditions
- Depression / Major Depressive Disorder, Anxiety, Anxiety Disorder Generalized
- Trial name
- CBT (NCT07873905)
- Testing
- Digital single-session cognitive behavioural therapy, Digital memory task
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Brunel University
Separation Anxiety Disorder, Generalized Anxiety Disorder
Acoustic Neuromodulation (ANM) for Youth With Anxiety Disorders
The acoustic neuromodulation trial (ANM-T) is a two-phase, single-site, pilot randomized clinical trial examining the feasibility of completing a larger scale efficacy study of a novel treatment of non-linear modulated acoustic…
- Conditions
- Separation Anxiety Disorder, Generalized Anxiety Disorder, Social Phobia
- Trial name
- ANM (NCT02572973)
- Testing
- Acoustic Neuromodulation (ANM)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Anxiety Disorder
Adjunctive Family CBT for Veterans With Anxiety
Despite the prevalence of posttraumatic stress disorder and anxiety disorders among Veterans, there has been limited focus on the development of interventions that include family members in treatments provided to Veterans.
- Trial name
- AF-CBT (NCT05340478)
- Testing
- Adjunctive Family - Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Schizophrenia Disorders, Major Depression
Non-Coding RNAs Gene Expression in Psychiatric Disorders
This study aims to investigate whether specific non-coding RNAs, molecules involved in the regulation of gene expression, are altered in individuals with psychiatric disorders such as schizophrenia, bipolar disorder, major…
- Conditions
- Schizophrenia Disorders, Major Depression, Bipolar Affective Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- PsiRNA26 (NCT07649993)
- Testing
- Reverse Transcription Quantitative Polymerase Chain Reaction
- Where
- 5 sites in Italy
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Carmen Concerto
Healthy Volunteers, Generalized Anxiety Disorder (GAD)
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of ABBV-932 in Healthy Adult Participants, Participants With Generalized Anxiety Disorder (GAD) and Participants With Bipolar Disorder (BPD)
The purpose of this study is to assess the pharmacokinetics, safety, and tolerability following multiple ascending oral doses of ABBV-932 or placebo in healthy adult participants, participants with Generalized Anxiety Disorder…
- Conditions
- Healthy Volunteers, Generalized Anxiety Disorder (GAD), Bipolar Disorder (BPD)
- Trial name
- MAD (NCT06024239)
- Testing
- ABBV-932
- Where
- 3 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- AbbVie
Depression in Adults, Anxiety Disorder Generalized
ACT for Individuals With MNCD and Their Care Partners
This project aims to implement and evaluate a dyadic intervention (i.e., acceptance commitment therapy) for persons with AD/ADRD and their care partners.
- Conditions
- Depression in Adults, Anxiety Disorder Generalized, Grief
- Trial name
- ACT (NCT07239609)
- Testing
- Acceptance Commitment Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Anxiety Disorder (Panic Disorder or GAD), Anxiety Symptoms
Anxiety is One of the Most Frequent Disorders During the Perinatal Stage Which is Associated with Adverse Health Effects for Women and Their Babies. This Study Will Be to Evaluate the Effectiveness of a Telematic Cognitive-behavioral Preventive Intervention to Manage Anxiety During Pregnancy.
Anxiety is one of the most frequent disorders during the perinatal stage which is associated with adverse health effects for women and their babies. In spite of this, preventive interventions during this stage are scarce.
- Trial name
- NCT06609291
- Testing
- Telematic Prenatal Psychological Intervention for Preventing Anxious Symptomatology
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Anxiety Disorders
Transdiagnostic Treatment for Anxiety Disorders in Two Cities of México
This study evaluates the effectiveness of The Unified Transdiagnostic Protocol, a psychological treatment for the intervention of a broad range of anxiety disorders.
- Trial name
- NCT03916315
- Testing
- Transdiagnostic Treatment
- Where
- 2 sites in Mexico
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Generalized Anxiety Disorder, Major Depressive Disorder
Development of Online EMDR Therapy System and Its Comparative Testing With Face-to-Face EMDR Therapy for Treatment of Anxiety and Depressive Disorders in Pakistan
This study aims at developing an online system for the remote delivery of EMDR therapy in Pakistan. Moreover, this study will compare the efficacy of online EMDR therapy with face-to-face EMDR therapy.
- Conditions
- Generalized Anxiety Disorder, Major Depressive Disorder, Social Anxiety Disorder, Somatic Symptom
- Trial name
- NCT05785312
- Testing
- Online EMDR Therapy System, Face to Face Eye Movement Desensitization & Reprocessing Therapy
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Khushal Khan Khattak Univeristy, Karak, Pakistan
Autism, Asperger's Syndrome
Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism spectrum disorders affect as many as 1 out of 150 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT01178385
- Testing
- Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Generalized Anxiety Disorder (GAD)
Effectiveness of Solution-Focused Therapy for Generalized Anxiety Disorder in Emerging Adults
This study will evaluate whether Solution-Focused Therapy (SFT) helps reduce symptoms of Generalized Anxiety Disorder (GAD) in emerging adults in Pakistan.
- Trial name
- NCT07798063
- Testing
- Solution-Focused Therapy
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- International Islamic University, Islamabad
Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD)
Validation of the CIDI 5.0 Against the SCID-5 for Lifetime Mental Disorders
The World Health Organization Composite International Diagnostic Interview (CIDI) is a fully structured diagnostic tool designed for lay interviewers to assess the prevalence of mental and substance use disorders.
- Conditions
- Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT07604753
- Testing
- CIDI-5
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Anxiety, Obsessive Compulsive Disorder
Virtual Reality System to Increase Access to Exposure Therapy for Anxiety and OCD
Cognitive Behavioral Therapy with fear provoking exposures is the most effective therapy for anxiety disorders. Investigators aim to enhance this therapy with the use of virtual reality exposures and to make therapy more…
- Trial name
- NCT02713516
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Major Depressive Disorder, Generalized Anxiety
Scaling Mental Healthcare in COVID-19 With Voice Biomarkers
This study aims to advance research on group sessions for mental health. The first-of-its-kind study measuring various features in a group setting, combining rich metadata in creating state-of-the-art machine learning models, and…
- Trial name
- NCT04510519
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kintsugi Mindful Wellness, Inc.
Anxiety, Generalized Anxiety Disorder
Brain Stimulation & Generalized Anxiety Study
Examine the safety and effectiveness of the Fisher Wallace Cranial Electrotherapy Stimulator (CES) Device on Generalized Anxiety Disorder using two (2) 20-minute per day treatment sessions over eight weeks.
- Conditions
- Anxiety, Generalized Anxiety Disorder, Generalized Anxiety
- Trial name
- NCT04751864
- Testing
- Cranial Electrotherapy Stimulator (CES) Device
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ProofPilot